| Gene Symbol | TGFB1 |
| Entrez Gene ID | 397078 |
| Full Name | transforming growth factor beta 1 |
| Synonyms | TGF-BETA-1 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
ORF » Species Summary » Sus scrofa » TGFB1 cDNA ORF clone
| Gene Symbol | TGFB1 |
| Entrez Gene ID | 397078 |
| Full Name | transforming growth factor beta 1 |
| Synonyms | TGF-BETA-1 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
| mRNA | Protein | Name |
|---|---|---|
| XM_021093503.1 | XP_020949162.1 | transforming growth factor beta-1 isoform X1 |
| NM_214015.2 | NP_999180.2 | transforming growth factor beta-1 proprotein precursor |
Focal adhesion kinase signaling determines the fate of lung epithelial cells in response to TGF-?.
Ding Q, Subramanian I, Luckhardt TR, Che P, Waghray M, Zhao XK, Bone N, Kurundkar AR, Hecker L, Hu M, Zhou Y, Horowitz JC, Vittal R, Thannickal VJ
American journal of physiology. Lung cellular and molecular physiology312(6)L926-L935(2017 Jun)
TGF-?1 protects intestinal integrity and influences Smads and MAPK signal pathways in IPEC-J2 after TNF-? challenge.
Xiao K, Cao S, Jiao L, Song Z, Lu J, Hu C
Innate immunity23(3)276-284(2017 04)
TGF-? signaling controls FSHR signaling-reduced ovarian granulosa cell apoptosis through the SMAD4/miR-143 axis.
Du X, Zhang L, Li X, Pan Z, Liu H, Li Q
Cell death & disease7(11)e2476(2016 Nov)
TGF-?1 autocrine signalling and enamel matrix components.
Kobayashi-Kinoshita S, Yamakoshi Y, Onuma K, Yamamoto R, Asada Y
Scientific reports633644(2016 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
TGF-beta1-induced epithelial-myofibroblast plasticity is FAK- dependent, whereas TGF-beta1-induced apoptosis is favored when FAK signaling is inhibited.
Title: Focal adhesion kinase signaling determines the fate of lung epithelial cells in response to TGF-?.
this study shows that TGF-beta1 protects intestinal integrity and influences Smad and MAPK signal pathways in intestinal epithelium cells after TNF-alpha challenge
Title: TGF-?1 protects intestinal integrity and influences Smads and MAPK signal pathways in IPEC-J2 after TNF-? challenge.
Activated TGF-beta signaling rescued miR-143-reduced FSHR and intracellular signaling molecules, and miR-143-induced porcine granulosa cell apoptosis.
Title: TGF-? signaling controls FSHR signaling-reduced ovarian granulosa cell apoptosis through the SMAD4/miR-143 axis.
this study shows that anemonin may ameliorate LPS-induced intestinal injury and improve restoration by regulating the TGF-b1 and EGFR signaling pathways
Title: Anemonin improves intestinal barrier restoration and influences TGF-?1 and EGFR signaling pathways in LPS-challenged piglets.
The results indicated that TGF-beta-1 was associated with the restoration of intestinal morphology and barrier function following weaning stress.
Title: Developmental changes of TGF-?1 and Smads signaling pathway in intestinal adaption of weaned pigs.
The following TGFB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGFB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe130690 | |
| Clone ID Related Accession (Same CDS sequence) | NM_214015.2 | |
| Accession Version | NM_214015.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-22 | |
| Organism | Sus scrofa(pig) | |
| Product | transforming growth factor beta-1 proprotein precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from Y00111.1, HX240216.1 and DB806948.1. On Feb 17, 2017 this sequence version replaced NM_214015.1. Sequence Note: This RefSeq record was created from transcripts of different breeds because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end. | |
1 | ATGCCGCCTT CGGGGCTGCG GCTCTTGCCG CTGCTGCTGC CGCTGCTGTG GCTGCTAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_999180.2 |
| CDS | 404..1576 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_214015.2 |
1 | ATGCCGCCTT CGGGGCTGCG GCTCTTGCCG CTGCTGCTGC CGCTGCTGTG GCTGCTAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe250466 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021093503.1 | |
| Accession Version | XM_021093503.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1176bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-05-12 | |
| Organism | Sus scrofa(pig) | |
| Product | transforming growth factor beta-1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010448.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCGCCTT CGGGGCTGCG GCTCTTGCCG CTGCTGCTGC CGCTGCTGTG GCTGCTAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_020949162.1 |
| CDS | 445..1620 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021093503.1 |
1 | ATGCCGCCTT CGGGGCTGCG GCTCTTGCCG CTGCTGCTGC CGCTGCTGTG GCTGCTAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Focal adhesion kinase signaling determines the fate of lung epithelial cells in response to TGF-?. |
TGF-?1 protects intestinal integrity and influences Smads and MAPK signal pathways in IPEC-J2 after TNF-? challenge. |
TGF-? signaling controls FSHR signaling-reduced ovarian granulosa cell apoptosis through the SMAD4/miR-143 axis. |
TGF-?1 autocrine signalling and enamel matrix components. |