TIMP1 cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	TIMP1
Entrez Gene ID	396862
Full Name	TIMP metallopeptidase inhibitor 1
Synonyms	TIMP-1
Gene Type	protein-coding
Organism	Sus scrofa(pig)
Genome	Chromosome: X Map Location: X\|Xp

mRNA and Protein(s)

mRNA	Protein	Name
NM_213857.1	NP_999022.1	metalloproteinase inhibitor 1 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1.
Ho TY, Rahman KM, Camp ME, Wiley AA, Bartol FF, Bagnell CA
Domestic animal endocrinology591-10(2017 Apr)

Expression and complex formation of MMP9, MMP2, NGAL, and TIMP1 in porcine myocardium but not in skeletal muscles in male pigs with tachycardia-induced systolic heart failure.
Kiczak L, Tomaszek A, Bania J, Paslawska U, Zacharski M, Noszczyk-Nowak A, Janiszewski A, Skrzypczak P, Ardehali H, Jankowska EA, Ponikowski P
BioMed research international2013283856(2013)

Role of a LIF antagonist in LIF and OSM induced MMP-1, MMP-3, and TIMP-1 expression by primary articular chondrocytes.
Upadhyay A, Sharma G, Kivivuori S, Raye WS, Zabihi E, Carroll GJ, Jazayeri JA
Cytokine46(3)332-8(2009 Jun)

Increased shear stress with upregulation of VEGF-A and its receptors and MMP-2, MMP-9, and TIMP-1 in venous stenosis of hemodialysis grafts.
Misra S, Fu AA, Puggioni A, Karimi KM, Mandrekar JN, Glockner JF, Juncos LA, Anwer B, McGuire AM, Mukhopadhyay D
American journal of physiology. Heart and circulatory physiology294(5)H2219-30(2008 May)

An integrated comparative map of the porcine X chromosome.
McCoard SA, Fahrenkrug SC, Alexander LJ, Freking BA, Rohrer GA, Wise TH, Ford JJ
Animal genetics33(3)178-85(2002 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results provide evidence for the utility of MMP9 and TIMP1 as markers of age- and lactocrine-sensitive porcine female reproductive tract development.
Title: Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1.

we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9, TIMP1, and NGAL (also MMP2 in 220 kDa complex) without proteolytic activity.
Title: Expression and complex formation of MMP9, MMP2, NGAL, and TIMP1 in porcine myocardium but not in skeletal muscles in male pigs with tachycardia-induced systolic heart failure.

Results indicate that leukemia inhibitory factor (LIF) and Oncostatin M increase the expression of MMP-1, MMP-3, and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF antagonist MH35-BD.
Title: Role of a LIF antagonist in LIF and OSM induced MMP-1, MMP-3, and TIMP-1 expression by primary articular chondrocytes.

Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A, pro-MMP-9, MMP-2, VEGFR-1, VEGFR-2, and TIMP-1, which may contribute to the development of venous stenosis.
Title: Increased shear stress with upregulation of VEGF-A and its receptors and MMP-2, MMP-9, and TIMP-1 in venous stenosis of hemodialysis grafts.

The following TIMP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TIMP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe00650	NM_213857.1 Latest version!	Sus scrofa TIMP metallopeptidase inhibitor 1 (TIMP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TIMP1 ( NM_213857.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_999022.1 Sus scrofa TIMP metallopeptidase inhibitor 1 (TIMP1), mRNA.

Price & Availability↑

CloneID	OSe00650
Clone ID Related Accession (Same CDS sequence)	NM_213857.1
Accession Version	NM_213857.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Sus scrofa(pig)
Product	metalloproteinase inhibitor 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from S96211.1. ##Evidence-Data-START## Transcript exon combination :: S96211.1, BX674336.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01048241, SAMN01048242 [ECO:0000348] ##Evidence-Data-END##

ATGAGCCCCT TTGCACCCCT GGCCTCTGGC ATCCTGCTGC TGCTGTGGCT GACTGCCCCC 
AGCCGAGCCT GTACCTGCGT CCCACCCCAC CCACAGACGG CCTTCTGCAG CTCCGACCTG 
GTCATCAGGG CCAAGTTTGT GGGAGCCCCA GAGTTCAACC AGACCGCCTC GTACCAGCGT 
TATGAGATCA AGATGACCAA GATGTTCAAA GGGTTCAATG CCTTGGGGGA TGCCCCTGAC 
ATCCGGTTCA TCTACACCCC CGCCATGGAG AGCGTCTGCG GATACTTCCA CAGGTCCCAG 
AACCGCAGCC AGGAGTTTCT CATAGCTGGA CAACTGTGGA ACGGGCACCT GCACATCACC 
ACCTGCAGTT TTGTGGCTCC CTGGAACAGT CTGAGCTCAG CTCAGCGCCA GGGCTTCACC 
GAGATCTATG CTGCTGGCTG TGAGGAATGC ACAGTGTTTC CCTGCACATC CATCCCCTGC 
AAACTGCAGA GTGACACTCA CTGCTTGTGG ACAGACCAGC TCCTCACAGG CTCTGACAAG 
GGCTTCCAGA GCCGCCACCT TGCCTGCATG CCCCGGGAGC CAGGAATGTG CACCTGGCAG 
TCCTTGCGGC CCCGGGTGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_999022.1
CDS	13..636
Translation	MSPFAPLASGILLLLWLTAPSRACTCVPPHPQTAFCSSDLVIRAKFVGAPEFNQTASYQRYEIKMTKMFKGFNALGDAPDIRFIYTPAMESVCGYFHRSQNRSQEFLIAGQLWNGHLHITTCSFVAPWNSLSSAQRQGFTEIYAAGCEECTVFPCTSIPCKLQSDTHCLWTDQLLTGSDKGFQSRHLACMPREPGMCTWQSLRPRVA

Target ORF information:

RefSeq Version	NM_213857.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa TIMP metallopeptidase inhibitor 1 (TIMP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213857.1

ORF Insert Sequence:

ATGAGCCCCT TTGCACCCCT GGCCTCTGGC ATCCTGCTGC TGCTGTGGCT GACTGCCCCC 
AGCCGAGCCT GTACCTGCGT CCCACCCCAC CCACAGACGG CCTTCTGCAG CTCCGACCTG 
GTCATCAGGG CCAAGTTTGT GGGAGCCCCA GAGTTCAACC AGACCGCCTC GTACCAGCGT 
TATGAGATCA AGATGACCAA GATGTTCAAA GGGTTCAATG CCTTGGGGGA TGCCCCTGAC 
ATCCGGTTCA TCTACACCCC CGCCATGGAG AGCGTCTGCG GATACTTCCA CAGGTCCCAG 
AACCGCAGCC AGGAGTTTCT CATAGCTGGA CAACTGTGGA ACGGGCACCT GCACATCACC 
ACCTGCAGTT TTGTGGCTCC CTGGAACAGT CTGAGCTCAG CTCAGCGCCA GGGCTTCACC 
GAGATCTATG CTGCTGGCTG TGAGGAATGC ACAGTGTTTC CCTGCACATC CATCCCCTGC 
AAACTGCAGA GTGACACTCA CTGCTTGTGG ACAGACCAGC TCCTCACAGG CTCTGACAAG 
GGCTTCCAGA GCCGCCACCT TGCCTGCATG CCCCGGGAGC CAGGAATGTG CACCTGGCAG 
TCCTTGCGGC CCCGGGTGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1.
Domestic animal endocrinology591-10(2017 Apr)
Ho TY,Rahman KM,Camp ME,Wiley AA,Bartol FF,Bagnell CA

Expression and complex formation of MMP9, MMP2, NGAL, and TIMP1 in porcine myocardium but not in skeletal muscles in male pigs with tachycardia-induced systolic heart failure.
BioMed research international2013283856(2013)
Kiczak L,Tomaszek A,Bania J,Paslawska U,Zacharski M,Noszczyk-Nowak A,Janiszewski A,Skrzypczak P,Ardehali H,Jankowska EA,Ponikowski P

Role of a LIF antagonist in LIF and OSM induced MMP-1, MMP-3, and TIMP-1 expression by primary articular chondrocytes.
Cytokine46(3)332-8(2009 Jun)
Upadhyay A,Sharma G,Kivivuori S,Raye WS,Zabihi E,Carroll GJ,Jazayeri JA

Increased shear stress with upregulation of VEGF-A and its receptors and MMP-2, MMP-9, and TIMP-1 in venous stenosis of hemodialysis grafts.
American journal of physiology. Heart and circulatory physiology294(5)H2219-30(2008 May)
Misra S,Fu AA,Puggioni A,Karimi KM,Mandrekar JN,Glockner JF,Juncos LA,Anwer B,McGuire AM,Mukhopadhyay D

An integrated comparative map of the porcine X chromosome.
Animal genetics33(3)178-85(2002 Jun)
McCoard SA,Fahrenkrug SC,Alexander LJ,Freking BA,Rohrer GA,Wise TH,Ford JJ

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

[email protected]

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

TIMP1 cDNA ORF clone, Sus scrofa(pig)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム