Rsad2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rsad2
Entrez Gene ID	65190
Full Name	radical S-adenosyl methionine domain containing 2
Synonyms	Best5,Vig1
General protein information	Preferred Names radical S-adenosyl methionine domain containing 2 Names radical S-adenosyl methionine domain-containing protein 2 bone-expressed sequence tag 5 protein viperin virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q16
Summary	protein involved in bone formation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_138881.1	NP_620236.1	radical S-adenosyl methionine domain-containing protein 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RSAD2	XP_851276.1
Danio rerio (zebrafish)	rsad2	NP_001020727.1
Pan troglodytes (chimpanzee)	RSAD2	XP_515283.2
	RSAD2	XP_001099610.1
Bos taurus (cattle)	RSAD2	NP_001039406.1
Mus musculus (house mouse)	Rsad2	NP_067359.2
Xenopus tropicalis (tropical clawed frog)	rsad2	XP_002935073.1
Rattus norvegicus (Norway rat)	Rsad2	NP_620236.1
Gallus gallus (chicken)	RSAD2	XP_426208.2
Homo sapiens (human)	RSAD2	NP_542388.2

Gene Ontology
Bibliography

Related articles in PubMed

Viperin restricts chikungunya virus replication and pathology.
Teng TS, Foo SS, Simamarta D, Lum FM, Teo TH, Lulla A, Yeo NK, Koh EG, Chow A, Leo YS, Merits A, Chin KC, Ng LF
The Journal of clinical investigation122(12)4447-60(2012 Dec)

Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33.
Wang S, Wu X, Pan T, Song W, Wang Y, Zhang F, Yuan Z
The Journal of general virology93(Pt 1)83-92(2012 Jan)

The interferon-inducible gene viperin restricts West Nile virus pathogenesis.
Szretter KJ, Brien JD, Thackray LB, Virgin HW, Cresswell P, Diamond MS
Journal of virology85(22)11557-66(2011 Nov)

Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity.
Seo JY, Yaneva R, Hinson ER, Cresswell P
Science (New York, N.Y.)332(6033)1093-7(2011 May)

Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells.
Saitoh T, Satoh T, Yamamoto N, Uematsu S, Takeuchi O, Kawai T, Akira S
Immunity34(3)352-63(2011 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Rsad2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rsad2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01858	NM_138881.1 Latest version!	Rattus norvegicus radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rsad2 ( NM_138881.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_620236.1 Rattus norvegicus radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA.

Price & Availability↑

CloneID	ORa01858
Clone ID Related Accession (Same CDS sequence)	NM_138881.1
Accession Version	NM_138881.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	radical S-adenosyl methionine domain-containing protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y07704.1. On Jan 12, 2005 this sequence version replaced XM_346761.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y07704.1, FQ181363.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906356 [ECO:0000348] ##Evidence-Data-END##

ATGCTAGTGC CTACTGCGCT GGCTGCTCGG CTGCTGAGCC TGTTCCAGCA ACAGCTGGGT 
TCCCTCTGGA GTGGCCTGGC CATGCTGTTC TGCTGGCTGA GAATAGCATT GGGGTGGCCA 
GATCCTGGAA AGGGACAGCC ACGGGTCCGG GGTGAGCCCA AGGAGACTCA GGAGACCCAC 
GAAGATCCAG GCAGTGCTCA GCCCACAACC CCCGTTAGTG TCAACTACCA CTTCACGCGT 
CAGTGCAACT ACAAATGTGG CTTCTGCTTC CACACGGCCA AGACATCCTT CGTGCTGCCC 
CTGGAGGAGG CCAAGCGAGG ACTGCTTCTG CTCAAACAGG CTGGTATGGA GAAGATCAAC 
TTTTCAGGAG GAGAACCCTT CCTACAGGAC AGGGGTGAAT ACTTGGGCAA GCTCGTGAGA 
TTCTGCAAGG AGGAGCTAGC CCTGCCCTCT GTGAGCATAG TGAGCAATGG CAGCCTTATC 
CGAGAGAGAT GGTTCAAGGA CTATGGAGAC TATTTGGACA TTCTTGCTAT CTCCTGTGAC 
AGCTTTGATG AGCAGGTTAA TGTTCTCATT GGTCGTGGCC AAGGGAAAAA GAACCATGTG 
GAAAACCTTC AAAAGCTGCG GAAGTGGTGC AGGGATTACA AGGTGGCTTT CAAGATCAAT 
TCCGTCATTA ATCGCTTCAA CGTGGACGAA GATATGAATG AGCACATCAA GGCGCTGAGC 
CCTGTCCGCT GGAAGGTTTT CCAATGCCTC CTGATTGAGG GTGAGAACTC AGGAGAAGAT 
GCCCTGAGGG AAGCAGAAAG ATTTCTTATA AGCAATGAAG AATTTGAAGC ATTCTTACAG 
CGTCACAAAG ATGTGTCCTG CTTGGTGCCT GAATCTAACC AGAAGATGAA AGACTCCTAC 
CTTATCCTGG ATGAATATAT GCGCTTTTTG AACTGTACCG GTGGCCGGAA GGACCCTTCC 
AGGTCCATCC TGGATGTTGG CGTGGAGGAA GCGATCAAAT TCAGTGGGTT TGATGAGAAG 
ATGTTTCTGA AGCGCGGGGG GAAGTATGTA TGGAGTAAGG CTGACCTGAA GCTAGACTGG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620236.1
CDS	6..1088
Translation	MLVPTALAARLLSLFQQQLGSLWSGLAMLFCWLRIALGWPDPGKGQPRVRGEPKETQETHEDPGSAQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGMEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGDYLDILAISCDSFDEQVNVLIGRGQGKKNHVENLQKLRKWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFEAFLQRHKDVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSRSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW

Target ORF information:

RefSeq Version	NM_138881.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus radical S-adenosyl methionine domain containing 2 (Rsad2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138881.1

ORF Insert Sequence:

ATGCTAGTGC CTACTGCGCT GGCTGCTCGG CTGCTGAGCC TGTTCCAGCA ACAGCTGGGT 
TCCCTCTGGA GTGGCCTGGC CATGCTGTTC TGCTGGCTGA GAATAGCATT GGGGTGGCCA 
GATCCTGGAA AGGGACAGCC ACGGGTCCGG GGTGAGCCCA AGGAGACTCA GGAGACCCAC 
GAAGATCCAG GCAGTGCTCA GCCCACAACC CCCGTTAGTG TCAACTACCA CTTCACGCGT 
CAGTGCAACT ACAAATGTGG CTTCTGCTTC CACACGGCCA AGACATCCTT CGTGCTGCCC 
CTGGAGGAGG CCAAGCGAGG ACTGCTTCTG CTCAAACAGG CTGGTATGGA GAAGATCAAC 
TTTTCAGGAG GAGAACCCTT CCTACAGGAC AGGGGTGAAT ACTTGGGCAA GCTCGTGAGA 
TTCTGCAAGG AGGAGCTAGC CCTGCCCTCT GTGAGCATAG TGAGCAATGG CAGCCTTATC 
CGAGAGAGAT GGTTCAAGGA CTATGGAGAC TATTTGGACA TTCTTGCTAT CTCCTGTGAC 
AGCTTTGATG AGCAGGTTAA TGTTCTCATT GGTCGTGGCC AAGGGAAAAA GAACCATGTG 
GAAAACCTTC AAAAGCTGCG GAAGTGGTGC AGGGATTACA AGGTGGCTTT CAAGATCAAT 
TCCGTCATTA ATCGCTTCAA CGTGGACGAA GATATGAATG AGCACATCAA GGCGCTGAGC 
CCTGTCCGCT GGAAGGTTTT CCAATGCCTC CTGATTGAGG GTGAGAACTC AGGAGAAGAT 
GCCCTGAGGG AAGCAGAAAG ATTTCTTATA AGCAATGAAG AATTTGAAGC ATTCTTACAG 
CGTCACAAAG ATGTGTCCTG CTTGGTGCCT GAATCTAACC AGAAGATGAA AGACTCCTAC 
CTTATCCTGG ATGAATATAT GCGCTTTTTG AACTGTACCG GTGGCCGGAA GGACCCTTCC 
AGGTCCATCC TGGATGTTGG CGTGGAGGAA GCGATCAAAT TCAGTGGGTT TGATGAGAAG 
ATGTTTCTGA AGCGCGGGGG GAAGTATGTA TGGAGTAAGG CTGACCTGAA GCTAGACTGG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Viperin restricts chikungunya virus replication and pathology.
The Journal of clinical investigation122(12)4447-60(2012 Dec)
Teng TS,Foo SS,Simamarta D,Lum FM,Teo TH,Lulla A,Yeo NK,Koh EG,Chow A,Leo YS,Merits A,Chin KC,Ng LF

Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33.
The Journal of general virology93(Pt 1)83-92(2012 Jan)
Wang S,Wu X,Pan T,Song W,Wang Y,Zhang F,Yuan Z

The interferon-inducible gene viperin restricts West Nile virus pathogenesis.
Journal of virology85(22)11557-66(2011 Nov)
Szretter KJ,Brien JD,Thackray LB,Virgin HW,Cresswell P,Diamond MS

Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity.
Science (New York, N.Y.)332(6033)1093-7(2011 May)
Seo JY,Yaneva R,Hinson ER,Cresswell P

Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells.
Immunity34(3)352-63(2011 Mar)
Saitoh T,Satoh T,Yamamoto N,Uematsu S,Takeuchi O,Kawai T,Akira S