Steap4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Steap4
Entrez Gene ID	499991
Full Name	STEAP4 metalloreductase
General protein information	Preferred Names STEAP4 metalloreductase Names metalloreductase STEAP4 Ab1-219 STEAP family member 4 six-transmembrane epithelial antigen of prostate 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001044265.1	NP_001037730.1	metalloreductase STEAP4

Pathways from BioSystems

Homologies

Bos taurus (cattle)	STEAP4	XP_002686905.1
Danio rerio (zebrafish)	steap4	XP_005158128.1
Rattus norvegicus (Norway rat)	Steap4	NP_001037730.1
Pan troglodytes (chimpanzee)	STEAP4	XP_001164605.1
	STEAP4	XP_001104041.1
Xenopus tropicalis (tropical clawed frog)	LOC100145516	NP_001120430.1
Mus musculus (house mouse)	Steap4	NP_473439.2
Homo sapiens (human)	STEAP4	NP_001192244.1
Canis lupus familiaris (dog)	STEAP4	XP_005628536.1
Gallus gallus (chicken)	STEAP4	XP_001235257.3
Xenopus tropicalis (tropical clawed frog)	steap4	NP_001015852.1

Gene Ontology
Bibliography

Related articles in PubMed

The crystal structure of six-transmembrane epithelial antigen of the prostate 4 (Steap4), a ferri/cuprireductase, suggests a novel interdomain flavin-binding site.
Gauss GH, Kleven MD, Sendamarai AK, Fleming MD, Lawrence CM
The Journal of biological chemistry288(28)20668-82(2013 Jul)

The Steap proteins are metalloreductases.
Ohgami RS, Campagna DR, McDonald A, Fleming MD
Blood108(4)1388-94(2006 Aug)

Tumor necrosis factor-alpha-induced adipose-related protein (TIARP), a cell-surface protein that is highly induced by tumor necrosis factor-alpha and adipose conversion.
Moldes M, Lasnier F, Gauthereau X, Klein C, Pairault J, F?ve B, Chambaut-Gu?rin AM
The Journal of biological chemistry276(36)33938-46(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that Steap4 utilizes an interdomain flavin-binding site to shuttle electrons between the oxidoreductase and transmembrane domains.
Title: The crystal structure of six-transmembrane epithelial antigen of the prostate 4 (Steap4), a ferri/cuprireductase, suggests a novel interdomain flavin-binding site.

The following Steap4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Steap4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06332	NM_001044265.1 Latest version!	Rattus norvegicus STEAP4 metalloreductase (Steap4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$279.30 $399.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Steap4 ( NM_001044265.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001037730.1 Rattus norvegicus STEAP4 metalloreductase (Steap4), mRNA.

Price & Availability↑

CloneID	ORa06332
Clone ID Related Accession (Same CDS sequence)	NM_001044265.1
Accession Version	NM_001044265.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1413bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	metalloreductase STEAP4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097353.1. On or before Aug 24, 2006 this sequence version replaced XM_575346.2, XM_001067033.1. ##Evidence-Data-START## Transcript exon combination :: BC097353.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906357 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGA CGTGTGCAGA TGAGTTTCCT CTGACTGTGG ATTCCTCAGA AAAGCAAGGC 
GTTGTCTGCA TTTTCGGAAC AGGGGATTTC GGGAAATCAT TGGGGTTGAA AATGCTTCAG 
TGTGGCTATT CTGTTGTTTT CGGGAGTCGA AACCCCCAGG TATCCAGCCT TCTGCCCAGG 
GGAGCAGAGG TCCTGTGCTA CTCAGAAGCA GCATCGAGGT CTGACGTCAT AGTCCTGGCC 
GTGCACAGAG AGCATTATGA TTTCCTCGCA GAATTAGCTG ATTCTCTCAA AGGAAGAGTA 
TTGATAGATG TCAGTAACAA CCAAAAAATG AATCAGTATC CAGAATCAAA CGCCGAGTAC 
CTTGCTCAGC TGGTACCAGG AGCCCACGTG GTCAAGGCAT TTAACACCAT CTCAGCCTGG 
GCTCTCCAGT CAGGAACACT AGATGCAAGT CGGCAGGTGT TTGTCTGTGG AAATGACAGC 
AAAGCCAAGG ACAGAGTGAT GGACATTGCT CGCACTCTTG GGCTCACTCC ACTGGATCAA 
GGATCTCTCG TGGCAGCCAA GGAAATTGAA AACTACCCTC TGCAACTATT TCCCATGTGG 
AGGTTCCCTT TCTACTTGTC CTCTGGGCTG TGCGTCTTCT TCTTTGTGTA CTGCGCTATA 
CGGGAAGTGA TATACCCCTA CGTGACTGGG AAGACAGATA GTACGTACCG CCTGGTTGTT 
TCCATCCCGA ATCGTGTCTT TCCTATAACA GCACTTACCC TGCTGGCGTT GGTGTACCTC 
CCTGGTATTC TCGCCGCCAT TTTGCAGCTC TACCGAGGCA CAAAGTACCG CCGATTCCCA 
AACTGGCTTG ACCATTGGAT GCTTTGCAGA AAGCAACTGG GCTTGGTAGC TCTGGGATTT 
GCCTTCCTTC ACGCCATCTA CACCCTTGTG ATTCCTATTC GTTACTACGT ACGATGGAGG 
CTGAGAAACG CGACCATTAC TCAGGCCCTA ACTAATAAAG ACAGCCCATT CAGTTCCTCT 
ACTGCCTGGC TCAGTGATTC CTATCTGGCC CTGGGAATTC TGGGATTTTT TCTGTTTCTT 
CTCTTGGGAA TCACTTCCTT GCCATCAGTA AGCAACATGG TCAACTGGAG AGAGTTCCGG 
TTTGTCCAGT CCAAACTGGG TTATCTGACC CTGGTCTTGT GCACAGCCCA CACTTTGGTG 
TATGGTGGAA AGAGATTCCT CAGCCCTTCA ATTCTAATAT GGAGCCTTCC TTCAGCCTAT 
ATTCTGGCGC TCATCATCCC CTGCACAGTG TTGGTGATGA AGTTTATCCT CATCATGCCG 
TGCATAGACA AGACCCTCAC GCGCATCCGC CAGGGCTGGG AAAGGAAGTC AAAATATGCA 
CAATCAACAC TGAACGGAAA ATCGGATATT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001037730.1
CDS	129..1541
Translation	MEKTCADEFPLTVDSSEKQGVVCIFGTGDFGKSLGLKMLQCGYSVVFGSRNPQVSSLLPRGAEVLCYSEAASRSDVIVLAVHREHYDFLAELADSLKGRVLIDVSNNQKMNQYPESNAEYLAQLVPGAHVVKAFNTISAWALQSGTLDASRQVFVCGNDSKAKDRVMDIARTLGLTPLDQGSLVAAKEIENYPLQLFPMWRFPFYLSSGLCVFFFVYCAIREVIYPYVTGKTDSTYRLVVSIPNRVFPITALTLLALVYLPGILAAILQLYRGTKYRRFPNWLDHWMLCRKQLGLVALGFAFLHAIYTLVIPIRYYVRWRLRNATITQALTNKDSPFSSSTAWLSDSYLALGILGFFLFLLLGITSLPSVSNMVNWREFRFVQSKLGYLTLVLCTAHTLVYGGKRFLSPSILIWSLPSAYILALIIPCTVLVMKFILIMPCIDKTLTRIRQGWERKSKYAQSTLNGKSDI

Target ORF information:

RefSeq Version	NM_001044265.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus STEAP4 metalloreductase (Steap4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001044265.1

ORF Insert Sequence:

ATGGAGAAGA CGTGTGCAGA TGAGTTTCCT CTGACTGTGG ATTCCTCAGA AAAGCAAGGC 
GTTGTCTGCA TTTTCGGAAC AGGGGATTTC GGGAAATCAT TGGGGTTGAA AATGCTTCAG 
TGTGGCTATT CTGTTGTTTT CGGGAGTCGA AACCCCCAGG TATCCAGCCT TCTGCCCAGG 
GGAGCAGAGG TCCTGTGCTA CTCAGAAGCA GCATCGAGGT CTGACGTCAT AGTCCTGGCC 
GTGCACAGAG AGCATTATGA TTTCCTCGCA GAATTAGCTG ATTCTCTCAA AGGAAGAGTA 
TTGATAGATG TCAGTAACAA CCAAAAAATG AATCAGTATC CAGAATCAAA CGCCGAGTAC 
CTTGCTCAGC TGGTACCAGG AGCCCACGTG GTCAAGGCAT TTAACACCAT CTCAGCCTGG 
GCTCTCCAGT CAGGAACACT AGATGCAAGT CGGCAGGTGT TTGTCTGTGG AAATGACAGC 
AAAGCCAAGG ACAGAGTGAT GGACATTGCT CGCACTCTTG GGCTCACTCC ACTGGATCAA 
GGATCTCTCG TGGCAGCCAA GGAAATTGAA AACTACCCTC TGCAACTATT TCCCATGTGG 
AGGTTCCCTT TCTACTTGTC CTCTGGGCTG TGCGTCTTCT TCTTTGTGTA CTGCGCTATA 
CGGGAAGTGA TATACCCCTA CGTGACTGGG AAGACAGATA GTACGTACCG CCTGGTTGTT 
TCCATCCCGA ATCGTGTCTT TCCTATAACA GCACTTACCC TGCTGGCGTT GGTGTACCTC 
CCTGGTATTC TCGCCGCCAT TTTGCAGCTC TACCGAGGCA CAAAGTACCG CCGATTCCCA 
AACTGGCTTG ACCATTGGAT GCTTTGCAGA AAGCAACTGG GCTTGGTAGC TCTGGGATTT 
GCCTTCCTTC ACGCCATCTA CACCCTTGTG ATTCCTATTC GTTACTACGT ACGATGGAGG 
CTGAGAAACG CGACCATTAC TCAGGCCCTA ACTAATAAAG ACAGCCCATT CAGTTCCTCT 
ACTGCCTGGC TCAGTGATTC CTATCTGGCC CTGGGAATTC TGGGATTTTT TCTGTTTCTT 
CTCTTGGGAA TCACTTCCTT GCCATCAGTA AGCAACATGG TCAACTGGAG AGAGTTCCGG 
TTTGTCCAGT CCAAACTGGG TTATCTGACC CTGGTCTTGT GCACAGCCCA CACTTTGGTG 
TATGGTGGAA AGAGATTCCT CAGCCCTTCA ATTCTAATAT GGAGCCTTCC TTCAGCCTAT 
ATTCTGGCGC TCATCATCCC CTGCACAGTG TTGGTGATGA AGTTTATCCT CATCATGCCG 
TGCATAGACA AGACCCTCAC GCGCATCCGC CAGGGCTGGG AAAGGAAGTC AAAATATGCA 
CAATCAACAC TGAACGGAAA ATCGGATATT TAA