The following Ern2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ern2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa08636 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001108919.1 | |
| Accession Version | NM_001108919.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2784bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | serine/threonine-protein kinase/endoribonuclease IRE2 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473956.2. On or before Oct 4, 2007 this sequence version replaced XM_001079523.1, XM_344959.3. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGGCGAGAC CAGTCCAGAG TTTCCAACTG TGGTCTGCCC TCGGGTTCCT GCTGCAGCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001102389.1 |
| CDS | 26..2809 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001108919.1 |
1 | ATGGCGAGAC CAGTCCAGAG TTTCCAACTG TGGTCTGCCC TCGGGTTCCT GCTGCAGCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa56757 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017589492.1 | |
| Accession Version | XM_017589492.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2862bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCGAGAC CAGTCCAGAG TTTCCAACTG TGGTCTGCCC TCGGGTTCCT GCTGCAGCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017444981.1 |
| CDS | 37..2898 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017589492.1 |
1 | ATGGCGAGAC CAGTCCAGAG TTTCCAACTG TGGTCTGCCC TCGGGTTCCT GCTGCAGCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. |
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. |
Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress. |
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. |
Cloning of mammalian Ire1 reveals diversity in the ER stress responses. |
