Wdr12 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Wdr12
Entrez Gene ID	363237
Full Name	WD repeat domain 12
General protein information	Preferred Names WD repeat domain 12 Names ribosome biogenesis protein WDR12 WD repeat-containing protein 12
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q32
Summary	mouse homolog is a propeller-folded protein containing seven WD repeat units which appears to bind Notch1 and may be involved in Notch signalling activity [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_199410.2	NP_955442.1	ribosome biogenesis protein WDR12
XM_017596520.1	XP_017452009.1	ribosome biogenesis protein WDR12 isoform X1
XM_017596519.1	XP_017452008.1	ribosome biogenesis protein WDR12 isoform X1
XM_017596518.1	XP_017452007.1	ribosome biogenesis protein WDR12 isoform X1
XM_017596521.1	XP_017452010.1	ribosome biogenesis protein WDR12 isoform X1

Pathways from BioSystems

Homologies

	WDR12	XP_001105358.1
Gallus gallus (chicken)	WDR12	XP_421945.4
Danio rerio (zebrafish)	wdr12	NP_955851.1
Eremothecium gossypii	AGOS_AER337W	NP_985193.2
Arabidopsis thaliana (thale cress)	AT5G15550	NP_197059.1
Xenopus tropicalis (tropical clawed frog)	wdr12	NP_001025628.1
Drosophila melanogaster (fruit fly)	CG6724	NP_609452.1
Canis lupus familiaris (dog)	WDR12	XP_536036.3
Mus musculus (house mouse)	Wdr12	NP_067287.1
Rattus norvegicus (Norway rat)	Wdr12	NP_955442.1
Caenorhabditis elegans (roundworm)	tag-345	NP_491655.1
Saccharomyces cerevisiae (baker's yeast)	YTM1	NP_014915.3
Oryza sativa (rice)	Os07g0600400	NP_001060197.1
Homo sapiens (human)	WDR12	NP_060726.3
Pan troglodytes (chimpanzee)	WDR12	NP_001233440.1
Bos taurus (cattle)	WDR12	NP_001069375.1
Anopheles gambiae (African malaria mosquito)	WDR12_ANOGA	XP_308556.3
Kluyveromyces lactis	KLLA0C07425g	XP_452530.1
Schizosaccharomyces pombe (fission yeast)	SPAC890.04c	NP_594822.1

Gene Ontology
Bibliography

Related articles in PubMed

WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function.
Moilanen AM, Rys? J, Kaikkonen L, Karvonen T, Mustonen E, Serpi R, Szab? Z, Tenhunen O, Bagyura Z, N?p?nkangas J, Ohukainen P, Tavi P, Kerkel? R, Le?sd?ttir M, Wahlstrand B, Hedner T, Melander O, Ruskoaho H
PloS one10(4)e0124907(2015)

Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.
Rohrmoser M, H?lzel M, Grimm T, Malamoussi A, Harasim T, Orban M, Pfisterer I, Gruber-Eber A, Kremmer E, Eick D
Molecular and cellular biology27(10)3682-94(2007 May)

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.
Grimm T, H?lzel M, Rohrmoser M, Harasim T, Malamoussi A, Gruber-Eber A, Kremmer E, Eick D
Nucleic acids research34(10)3030-43(2006)

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation.
H?lzel M, Rohrmoser M, Schlee M, Grimm T, Harasim T, Malamoussi A, Gruber-Eber A, Kremmer E, Hiddemann W, Bornkamm GW, Eick D
The Journal of cell biology170(3)367-78(2005 Aug)

Wdr12, a mouse gene encoding a novel WD-Repeat Protein with a notchless-like amino-terminal domain.
Nal B, Mohr E, Silva MI, Tagett R, Navarro C, Carroll P, Depetris D, Verthuy C, Jordan BR, Ferrier P
Genomics79(1)77-86(2002 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

WDR12 triggers distinct deterioration of cardiac function in adult rat heart.
Title: WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function.

The following Wdr12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wdr12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05359	NM_199410.2 Latest version!	Rattus norvegicus WD repeat domain 12 (Wdr12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa62809	XM_017596520.1 Latest version!	Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa62809	XM_017596518.1 Latest version!	Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa62809	XM_017596521.1 Latest version!	Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa62809	XM_017596519.1 Latest version!	Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Wdr12 ( NM_199410.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_955442.1 Rattus norvegicus WD repeat domain 12 (Wdr12), mRNA.

Price & Availability↑

CloneID	ORa05359
Clone ID Related Accession (Same CDS sequence)	NM_199410.2
Accession Version	NM_199410.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1272bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	ribosome biogenesis protein WDR12
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC063180.1. On Aug 30, 2012 this sequence version replaced NM_199410.1. ##Evidence-Data-START## Transcript exon combination :: BC063180.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CACACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_955442.1
CDS	124..1395
Translation	MAQLQARFYTENKKYAVDDVPFSIPATSEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRMPLVKHMELEDISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWSTVPTDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDADEVCSASWDHTVRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA

Target ORF information:

RefSeq Version	NM_199410.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat domain 12 (Wdr12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199410.2

ORF Insert Sequence:

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CACACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Wdr12 ( XM_017596520.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452009.1 Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa62809
Clone ID Related Accession (Same CDS sequence)	XM_017596520.1 , XM_017596519.1 , XM_017596518.1 , XM_017596521.1
Accession Version	XM_017596520.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1272bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ribosome biogenesis protein WDR12 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CATACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452009.1
CDS	339..1610
Translation	MAQLQARFYTENKKYAVDDVPFSIPATSEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRMPLVKHMELEDISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWSTVPTDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDADEVCSASWDHTVRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA

Target ORF information:

RefSeq Version	XM_017596520.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596520.1

ORF Insert Sequence:

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CATACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Wdr12 ( XM_017596519.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452008.1 Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa62809
Clone ID Related Accession (Same CDS sequence)	XM_017596520.1 , XM_017596519.1 , XM_017596518.1 , XM_017596521.1
Accession Version	XM_017596519.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1272bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ribosome biogenesis protein WDR12 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CATACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452008.1
CDS	285..1556
Translation	MAQLQARFYTENKKYAVDDVPFSIPATSEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRMPLVKHMELEDISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWSTVPTDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDADEVCSASWDHTVRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA

Target ORF information:

RefSeq Version	XM_017596519.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596519.1

ORF Insert Sequence:

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CATACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Wdr12 ( XM_017596518.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452007.1 Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X1, mRNA.

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CloneID	ORa62809
Clone ID Related Accession (Same CDS sequence)	XM_017596520.1 , XM_017596519.1 , XM_017596518.1 , XM_017596521.1
Accession Version	XM_017596518.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1272bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ribosome biogenesis protein WDR12 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CATACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452007.1
CDS	269..1540
Translation	MAQLQARFYTENKKYAVDDVPFSIPATSEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRMPLVKHMELEDISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWSTVPTDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDADEVCSASWDHTVRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA

Target ORF information:

RefSeq Version	XM_017596518.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596518.1

ORF Insert Sequence:

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CATACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Wdr12 ( XM_017596521.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452010.1 Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X4, mRNA.

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CloneID	ORa62809
Clone ID Related Accession (Same CDS sequence)	XM_017596520.1 , XM_017596519.1 , XM_017596518.1 , XM_017596521.1
Accession Version	XM_017596521.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1272bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ribosome biogenesis protein WDR12 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CATACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452010.1
CDS	312..1583
Translation	MAQLQARFYTENKKYAVDDVPFSIPATSEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRMPLVKHMELEDISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWSTVPTDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDADEVCSASWDHTVRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA

Target ORF information:

RefSeq Version	XM_017596521.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat domain 12 (Wdr12), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596521.1

ORF Insert Sequence:

ATGGCACAAC TCCAGGCACG TTTCTACACG GAGAACAAGA AATATGCAGT AGATGATGTT 
CCTTTCTCAA TCCCTGCCAC CTCAGAAGTT GCTGACCTTA GTAATATTAT CAATAAATTG 
CTGGAGACCA AAAATGAGCT CCACAAACAT GTCGAGTTTG ATTTCCTCAT CAAGGGCCAG 
TTTCTTCGAA TGCCCTTGGT CAAACACATG GAACTGGAAG ACATTTCATC GGAAGAGGTT 
GTGGAACTAG AATATGTGGA AAAATACACC GCACCCCAGC CAGAGCAATG CATGTTCCAC 
GATGACTGGA TCAGCTCAAT TAAAGGGGCA GAAGAATGGA TCCTGTCTGG TTCTTATGAT 
AAGACTTCTC GAATCTGGTC CTTGGAAGGA AAGTCAATAA TGACAATTGT GGGACATACA 
GATGTTGTGA AAGATGTGGC TTGGGTGAAA AAAGACAGTC TGTCTTGCCT ACTCCTGACG 
GCCTCGATGG ACCAGACTAT TCTCTTATGG GAGTGGAACA TAGAGAGGAA CAAAGTGAAG 
GCTCTTCACT GCTGCAGAGG GCATGCTGGG AGTGTGGACG CCATAGCAGT TGATAGCTCT 
GGAACTAAAT TCTGCAGTGG CTCCTGGGAT AAGATGCTGA AGATCTGGTC TACAGTCCCT 
ACAGATGAGG AAGATGAAAT ACAAGAACCC ACAAATCGAC CAAGAAAGAA GCAGAAAACA 
GAACAATTGG GACTGACAAG AACACCCTTG GTGACCCTCT CTGGCCACAC AGAAGCAATT 
TCCTCAGTAC TCTGGTCAGA TGCTGACGAA GTCTGCAGTG CCTCTTGGGA TCACACAGTC 
AGAGTGTGGG ATGTTGAGTC CGGAGGTCTT AAGTCAACTC TGACAGGAAA TAAGGTGTTC 
AATTGTATTT CCTATTCTCC CCTCTGTAAA CGTTTGGCGT CTGGAAGCAC AGACAGGCAC 
ATTAGGCTGT GGGATCCCCG AACTAAAGAT GGCTCTTTGG TGTCGCTGTC CCTCACCTCA 
CATACAGGCT GGGTAACATC AGTGAAGTGG TCACCTACCC ATGATCAGCA GCTGATCTCA 
GGCTCTTTAG ATAACATGGT GAAGCTATGG GATACGAGAA GTTGTAAGGC TCCTCTCTAC 
GACCTAGCTG CACATGAAGA CAAAGTTCTA AGTGTGGACT GGACAGACAC AGGGCTACTT 
CTGAGTGGAG GAGCAGACAA TAAATTGTAT TCCTACAGAT ATTCCCCTAC CACTTCCCAT 
GTGGGGGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function.
PloS one10(4)e0124907(2015)
Moilanen AM,Rys? J,Kaikkonen L,Karvonen T,Mustonen E,Serpi R,Szab? Z,Tenhunen O,Bagyura Z,N?p?nkangas J,Ohukainen P,Tavi P,Kerkel? R,Le?sd?ttir M,Wahlstrand B,Hedner T,Melander O,Ruskoaho H

Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.
Molecular and cellular biology27(10)3682-94(2007 May)
Rohrmoser M,H?lzel M,Grimm T,Malamoussi A,Harasim T,Orban M,Pfisterer I,Gruber-Eber A,Kremmer E,Eick D

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.
Nucleic acids research34(10)3030-43(2006)
Grimm T,H?lzel M,Rohrmoser M,Harasim T,Malamoussi A,Gruber-Eber A,Kremmer E,Eick D

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation.
The Journal of cell biology170(3)367-78(2005 Aug)
H?lzel M,Rohrmoser M,Schlee M,Grimm T,Harasim T,Malamoussi A,Gruber-Eber A,Kremmer E,Hiddemann W,Bornkamm GW,Eick D

Wdr12, a mouse gene encoding a novel WD-Repeat Protein with a notchless-like amino-terminal domain.
Genomics79(1)77-86(2002 Jan)
Nal B,Mohr E,Silva MI,Tagett R,Navarro C,Carroll P,Depetris D,Verthuy C,Jordan BR,Ferrier P

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Wdr12 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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