Kcnmb3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnmb3
Entrez Gene ID	310303
Full Name	potassium calcium-activated channel subfamily M regulatory beta subunit 3
General protein information	Preferred Names potassium calcium-activated channel subfamily M regulatory beta subunit 3 Names calcium-activated potassium channel subunit beta-3 calcium-activated potassium channel subfamily M subunit beta-3 maxi K channel subunit beta-3 potassium channel subfamily M regulatory beta subunit 3 potassium large conductance calcium-activated channel, subfamily M beta member 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001104560.2	NP_001098030.1	calcium-activated potassium channel subunit beta-3

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	kcnmb3	XP_004914476.1
Homo sapiens (human)	KCNMB3	NP_741979.1
Pan troglodytes (chimpanzee)	KCNMB3	XP_003310165.1
Mus musculus (house mouse)	Kcnmb3	NP_001182003.1
Rattus norvegicus (Norway rat)	Kcnmb3	NP_001098030.1
Bos taurus (cattle)	KCNMB3	NP_001178213.1

Gene Ontology
Bibliography

Related articles in PubMed

Rat GnRH neurons exhibit large conductance voltage- and Ca2+-Activated K+ (BK) currents and express BK channel mRNAs.
Hiraizumi Y, Nishimura I, Ishii H, Tanaka N, Takeshita T, Sakuma Y, Kato M
The journal of physiological sciences : JPS58(1)21-9(2008 Feb)

Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.
Brenner R, Jegla TJ, Wickenden A, Liu Y, Aldrich RW
The Journal of biological chemistry275(9)6453-61(2000 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kcnmb3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnmb3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00012	NM_001104560.2 Latest version!	Rattus norvegicus potassium calcium-activated channel subfamily M regulatory beta subunit 3 (Kcnmb3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnmb3 ( NM_001104560.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001098030.1 Rattus norvegicus potassium calcium-activated channel subfamily M regulatory beta subunit 3 (Kcnmb3), mRNA.

Price & Availability↑

CloneID	ORa00012
Clone ID Related Accession (Same CDS sequence)	NM_001104560.2
Accession Version	NM_001104560.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	calcium-activated potassium channel subunit beta-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB297662.1. On Aug 31, 2012 this sequence version replaced NM_001104560.1. ##Evidence-Data-START## Transcript exon combination :: AB297662.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN02642603, SAMN02642640 [ECO:0000350] ##Evidence-Data-END##

ATGCAGCCCT TCAGCATCCC GGTCCAAATC ACACTACAGG GTGGTCGGAG GCGCCAAGGG 
AGGACAGCAC TTCCGGCCTC AGGCATAAGC AATGGAGATC CCCTGAAGGT GCACCCAAAA 
CTTCCATCGA GCGCTGGTGA GGACCGGGCC ACGCTGCTGG GCATCGCCAT GATGGCCTCC 
TCCGTGCTGA TGTTCTTCCT GCTGGGGACC ACTGTGTTGA AGCCCTTCAT GCTCAGCTCT 
CCCAGAGAAG AATCAAACTG CACCACTGTC CACACACACA TTGCAGATGA TTGGCTGGAC 
TTTGCCTTCA CCTGTGAGGG TAGCTGCCAG GGCCAGGGGA CATACCCTTG CCTGCAGGTG 
TTCGTCAACC TTAGCCACTC GGGACAGAAA GTGCTTCTCC ATTACGATGA GGAGGCCATC 
AGGACCAACC CCAAGTGCTT TTACACACCC AAGTGTCACG GAGACAGGGA TCATCTGCTC 
AACAGTGCCC TGGACATCAA GGAATTCTTC GATCACAACA ATGGAACTTT CCCCTGCTTC 
TACAGTCCTG ACGGGCCCCT GGGAGTGGTC CTGAGGAAGT CTGGCCACAA GGTTGTCTTT 
CACTGCTTAT TTTGGCCTTT ACTGACATTG CTGGGAGGCG CTCTGATTGT TGGTTTGGTT 
AGGCTAACAC AACATCTGTC CTTTCAGTGT GAAAAGTATA GAGCAGTGGT AAGAGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001098030.1
CDS	261..980
Translation	MQPFSIPVQITLQGGRRRQGRTALPASGISNGDPLKVHPKLPSSAGEDRATLLGIAMMASSVLMFFLLGTTVLKPFMLSSPREESNCTTVHTHIADDWLDFAFTCEGSCQGQGTYPCLQVFVNLSHSGQKVLLHYDEEAIRTNPKCFYTPKCHGDRDHLLNSALDIKEFFDHNNGTFPCFYSPDGPLGVVLRKSGHKVVFHCLFWPLLTLLGGALIVGLVRLTQHLSFQCEKYRAVVRA

Target ORF information:

RefSeq Version	NM_001104560.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium calcium-activated channel subfamily M regulatory beta subunit 3 (Kcnmb3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001104560.2

ORF Insert Sequence:

ATGCAGCCCT TCAGCATCCC GGTCCAAATC ACACTACAGG GTGGTCGGAG GCGCCAAGGG 
AGGACAGCAC TTCCGGCCTC AGGCATAAGC AATGGAGATC CCCTGAAGGT GCACCCAAAA 
CTTCCATCGA GCGCTGGTGA GGACCGGGCC ACGCTGCTGG GCATCGCCAT GATGGCCTCC 
TCCGTGCTGA TGTTCTTCCT GCTGGGGACC ACTGTGTTGA AGCCCTTCAT GCTCAGCTCT 
CCCAGAGAAG AATCAAACTG CACCACTGTC CACACACACA TTGCAGATGA TTGGCTGGAC 
TTTGCCTTCA CCTGTGAGGG TAGCTGCCAG GGCCAGGGGA CATACCCTTG CCTGCAGGTG 
TTCGTCAACC TTAGCCACTC GGGACAGAAA GTGCTTCTCC ATTACGATGA GGAGGCCATC 
AGGACCAACC CCAAGTGCTT TTACACACCC AAGTGTCACG GAGACAGGGA TCATCTGCTC 
AACAGTGCCC TGGACATCAA GGAATTCTTC GATCACAACA ATGGAACTTT CCCCTGCTTC 
TACAGTCCTG ACGGGCCCCT GGGAGTGGTC CTGAGGAAGT CTGGCCACAA GGTTGTCTTT 
CACTGCTTAT TTTGGCCTTT ACTGACATTG CTGGGAGGCG CTCTGATTGT TGGTTTGGTT 
AGGCTAACAC AACATCTGTC CTTTCAGTGT GAAAAGTATA GAGCAGTGGT AAGAGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rat GnRH neurons exhibit large conductance voltage- and Ca2+-Activated K+ (BK) currents and express BK channel mRNAs.
The journal of physiological sciences : JPS58(1)21-9(2008 Feb)
Hiraizumi Y,Nishimura I,Ishii H,Tanaka N,Takeshita T,Sakuma Y,Kato M

Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.
The Journal of biological chemistry275(9)6453-61(2000 Mar)
Brenner R,Jegla TJ,Wickenden A,Liu Y,Aldrich RW