Ifrd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ifrd1
Entrez Gene ID	29596
Full Name	interferon-related developmental regulator 1
Synonyms	Pc4
General protein information	Preferred Names interferon-related developmental regulator 1 Names interferon-related developmental regulator 1 IRPR nerve growth factor-inducible protein PC4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q21
Summary	may have a role in signal transduction; necessary for muscle differentiation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019242.1	NP_062115.1	interferon-related developmental regulator 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	IFRD1	NP_001007246.1
Oryza sativa (rice)	Os07g0588000	NP_001060139.1
Arabidopsis thaliana (thale cress)	SAT32	NP_564294.1
Xenopus tropicalis (tropical clawed frog)	ifrd1	NP_001016124.1
Gallus gallus (chicken)	IFRD1	NP_001001468.1
Drosophila melanogaster (fruit fly)	CG31694	NP_722858.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001032	XP_003437180.1
Caenorhabditis elegans (roundworm)	F58B3.6	NP_502197.2
Pan troglodytes (chimpanzee)	IFRD1	XP_001167483.1
	IFRD1	XP_001099740.1
Canis lupus familiaris (dog)	IFRD1	XP_539525.2
Mus musculus (house mouse)	Ifrd1	NP_038590.2
Danio rerio (zebrafish)	ifrd1	NP_001070023.1
Oryza sativa (rice)	Os03g0448700	NP_001050472.1
Bos taurus (cattle)	IFRD1	NP_001029901.1
Rattus norvegicus (Norway rat)	Ifrd1	NP_062115.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression and regulation of the differentiation regulators ERBB Receptor Feedback Inhibitor 1 (ERRFI1) and Interferon-related Developmental Regulator 1 (IFRD1) during the periovulatory period in the rat ovary.
Li FX, Liu Y, Miao XP, Fu GQ, Curry TE Jr
Molecular reproduction and development83(8)714-23(2016 Aug)

The transcriptional corepressor TPA-inducible sequence 7 regulates adult axon growth through cellular retinoic acid binding protein II expression.
Dieplinger B, Schiefermeier N, Juchum-Pasquazzo M, Gstir R, Huber LA, Klimaschewski L, Vietor I
The European journal of neuroscience26(12)3358-67(2007 Dec)

PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C.
Micheli L, Leonardi L, Conti F, Buanne P, Canu N, Caruso M, Tirone F
Molecular and cellular biology25(6)2242-59(2005 Mar)

Muscle regeneration and myogenic differentiation defects in mice lacking TIS7.
Vadivelu SK, Kurzbauer R, Dieplinger B, Zweyer M, Schafer R, Wernig A, Vietor I, Huber LA
Molecular and cellular biology24(8)3514-25(2004 Apr)

Temporal and spatial gene expression patterns after experimental stroke in a rat model and characterization of PC4, a potential regulator of transcription.
Roth A, Gill R, Certa U
Molecular and cellular neurosciences22(3)353-64(2003 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PC4 acts as a coactivator of MyoD and MEF2C by removing the inhibitory effect of HDAC4, thus exerting a pivotal function during myogenesis.
Title: PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C.

PC4 is a regulator of transcription involved in tissue regeneration after ischemic stroke.
Title: Temporal and spatial gene expression patterns after experimental stroke in a rat model and characterization of PC4, a potential regulator of transcription.

The following Ifrd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ifrd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04130	NM_019242.1 Latest version!	Rattus norvegicus interferon-related developmental regulator 1 (Ifrd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ifrd1 ( NM_019242.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062115.1 Rattus norvegicus interferon-related developmental regulator 1 (Ifrd1), mRNA.

Price & Availability↑

CloneID	ORa04130
Clone ID Related Accession (Same CDS sequence)	NM_019242.1
Accession Version	NM_019242.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Rattus norvegicus(Norway rat)
Product	interferon-related developmental regulator 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J04511.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J04511.1, BC083560.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCCGAAGA ACAAGAAGCG GAACGCTCCC CACCGCGGTG GCGGGGGTGG CGGCGGCTCC 
GGGGCAGCGA CGTCGGCGGC CACGACAGGT GGCCCGCATC GGACTGTTCA ACCTTTCAGT 
GATGAAGACG CATCCATTGA AACAATGAGC CACTGCAGTG GCTATAGCGA TCCTTCCAGT 
TTCGCGGAGG ATGGACCAGA AGTTCTTGAT GAGGAAGGAA CTCAGGAAGA CTTAGAGTAC 
AAGTTGAAGG GATTAATTGA CCTAACCCTT GATAAGAGTG CGAAGACAAG ACAGGCAGCT 
CTTGAAGGTG TTAAAAATGC GCTGTCTTCA AAAGTGCTGT ATGAGTTTGT TCTCGAGAGA 
AGAATGACTT TAACTGATAG CATTGAGCGC TGTCTGAAAA AAGGAAAGAG TGATGGGCAG 
CGCGCAGCTG CAGCGCTCGC GTCCGTTCTT TGTATTCAGT TGGGCCCTGG ATTGGAAAGT 
GAAGAGATTT TAAAGACTCT TGGACCAATC CTAAAAAAAA TAATTTGTGA TGGAACAGCG 
AGTATCCAGG CTAGGCAGAC TTGTGCAACT TGCTTTGGTG TTTGCTGTTT TATTGCCACA 
GATGACATCA CTGAGCTGTA TTCAACTCTG GAGTGCTTGG AAGGTATCTT CACCAAGTCC 
TACCTTAAAG AGAAAGACAC GAACGTTCCT TGCAGCACTC CTAATACAGT GCTTCACATC 
AGCTCGCTTC TCGCATGGAC GCTACTGCTG ACCATATGCC CAATCAGTGA AGTGAAGAAA 
AAGCTGGAGC TGCATTTCCA TAAACTTCCA AGCCTCCTTT CTTGTGATGA TGTAAACATG 
AGAATTGCTG CTGGCGAATC TTTGGCACTT CTGTTTGAAT TGGCCAGAGG AATGGAGAGT 
GACTTTTTTT ATGAAGATAT GGATTCTTTG ACCCAGATGC TCCGGGCTCT GGCTACAGAT 
GGAAATAAAC ACCGTGCCAA AGTGGACAAG AGAAAGCAGC GCTCTGTCTT CAGAGACGTC 
CTGAGGGCTG TGGAGGAACG GGATTTTCCA ACAGAAACTG TTAAATTCGG TCCTGAGCGC 
ATGTATATTG ATAGCTGGGT CAAAAAGCAC ACCTATGACA CGTTTAAAGA GGCTCTTGGA 
TCAGGGATGC AGTACCACTT GCAGACAAAT GAATTCCTTC GCAATGTATT TGAGCTGGGG 
CCCCCTGTGA TGCTCGATGC TGCAACACTT AAAACCATGA AGATTCCTCG TTTTGAAAGG 
CATTTATATA ACTCTGCAGC TTTCAAAGCT CGAACAAAAG CCCGAAGCAA ATGCCGAGAT 
AAGAGAGCAG ATGTTGGAGA ATTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062115.1
CDS	146..1495
Translation	MPKNKKRNAPHRGGGGGGGSGAATSAATTGGPHRTVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGVKNALSSKVLYEFVLERRMTLTDSIERCLKKGKSDGQRAAAALASVLCIQLGPGLESEEILKTLGPILKKIICDGTASIQARQTCATCFGVCCFIATDDITELYSTLECLEGIFTKSYLKEKDTNVPCSTPNTVLHISSLLAWTLLLTICPISEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARGMESDFFYEDMDSLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETVKFGPERMYIDSWVKKHTYDTFKEALGSGMQYHLQTNEFLRNVFELGPPVMLDAATLKTMKIPRFERHLYNSAAFKARTKARSKCRDKRADVGEFF

Target ORF information:

RefSeq Version	NM_019242.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interferon-related developmental regulator 1 (Ifrd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019242.1

ORF Insert Sequence:

ATGCCGAAGA ACAAGAAGCG GAACGCTCCC CACCGCGGTG GCGGGGGTGG CGGCGGCTCC 
GGGGCAGCGA CGTCGGCGGC CACGACAGGT GGCCCGCATC GGACTGTTCA ACCTTTCAGT 
GATGAAGACG CATCCATTGA AACAATGAGC CACTGCAGTG GCTATAGCGA TCCTTCCAGT 
TTCGCGGAGG ATGGACCAGA AGTTCTTGAT GAGGAAGGAA CTCAGGAAGA CTTAGAGTAC 
AAGTTGAAGG GATTAATTGA CCTAACCCTT GATAAGAGTG CGAAGACAAG ACAGGCAGCT 
CTTGAAGGTG TTAAAAATGC GCTGTCTTCA AAAGTGCTGT ATGAGTTTGT TCTCGAGAGA 
AGAATGACTT TAACTGATAG CATTGAGCGC TGTCTGAAAA AAGGAAAGAG TGATGGGCAG 
CGCGCAGCTG CAGCGCTCGC GTCCGTTCTT TGTATTCAGT TGGGCCCTGG ATTGGAAAGT 
GAAGAGATTT TAAAGACTCT TGGACCAATC CTAAAAAAAA TAATTTGTGA TGGAACAGCG 
AGTATCCAGG CTAGGCAGAC TTGTGCAACT TGCTTTGGTG TTTGCTGTTT TATTGCCACA 
GATGACATCA CTGAGCTGTA TTCAACTCTG GAGTGCTTGG AAGGTATCTT CACCAAGTCC 
TACCTTAAAG AGAAAGACAC GAACGTTCCT TGCAGCACTC CTAATACAGT GCTTCACATC 
AGCTCGCTTC TCGCATGGAC GCTACTGCTG ACCATATGCC CAATCAGTGA AGTGAAGAAA 
AAGCTGGAGC TGCATTTCCA TAAACTTCCA AGCCTCCTTT CTTGTGATGA TGTAAACATG 
AGAATTGCTG CTGGCGAATC TTTGGCACTT CTGTTTGAAT TGGCCAGAGG AATGGAGAGT 
GACTTTTTTT ATGAAGATAT GGATTCTTTG ACCCAGATGC TCCGGGCTCT GGCTACAGAT 
GGAAATAAAC ACCGTGCCAA AGTGGACAAG AGAAAGCAGC GCTCTGTCTT CAGAGACGTC 
CTGAGGGCTG TGGAGGAACG GGATTTTCCA ACAGAAACTG TTAAATTCGG TCCTGAGCGC 
ATGTATATTG ATAGCTGGGT CAAAAAGCAC ACCTATGACA CGTTTAAAGA GGCTCTTGGA 
TCAGGGATGC AGTACCACTT GCAGACAAAT GAATTCCTTC GCAATGTATT TGAGCTGGGG 
CCCCCTGTGA TGCTCGATGC TGCAACACTT AAAACCATGA AGATTCCTCG TTTTGAAAGG 
CATTTATATA ACTCTGCAGC TTTCAAAGCT CGAACAAAAG CCCGAAGCAA ATGCCGAGAT 
AAGAGAGCAG ATGTTGGAGA ATTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression and regulation of the differentiation regulators ERBB Receptor Feedback Inhibitor 1 (ERRFI1) and Interferon-related Developmental Regulator 1 (IFRD1) during the periovulatory period in the rat ovary.
Molecular reproduction and development83(8)714-23(2016 Aug)
Li FX,Liu Y,Miao XP,Fu GQ,Curry TE Jr

The transcriptional corepressor TPA-inducible sequence 7 regulates adult axon growth through cellular retinoic acid binding protein II expression.
The European journal of neuroscience26(12)3358-67(2007 Dec)
Dieplinger B,Schiefermeier N,Juchum-Pasquazzo M,Gstir R,Huber LA,Klimaschewski L,Vietor I

PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C.
Molecular and cellular biology25(6)2242-59(2005 Mar)
Micheli L,Leonardi L,Conti F,Buanne P,Canu N,Caruso M,Tirone F

Muscle regeneration and myogenic differentiation defects in mice lacking TIS7.
Molecular and cellular biology24(8)3514-25(2004 Apr)
Vadivelu SK,Kurzbauer R,Dieplinger B,Zweyer M,Schafer R,Wernig A,Vietor I,Huber LA

Temporal and spatial gene expression patterns after experimental stroke in a rat model and characterization of PC4, a potential regulator of transcription.
Molecular and cellular neurosciences22(3)353-64(2003 Mar)
Roth A,Gill R,Certa U