Hs3st2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hs3st2
Entrez Gene ID	293451
Full Name	heparan sulfate-glucosamine 3-sulfotransferase 2
General protein information	Preferred Names heparan sulfate-glucosamine 3-sulfotransferase 2 Names heparan sulfate glucosamine 3-O-sulfotransferase 2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 heparan sulfate 3-O-sulfotransferase 2 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q36
Summary	catalyzes the transfer of sulfate groups onto the 3-OH site of glucosamine groups in heparan sulfate proteoglycans [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_181370.2	NP_852035.1	heparan sulfate glucosamine 3-O-sulfotransferase 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Hs3st2	NP_001074796.1
Gallus gallus (chicken)	HS3ST2	XP_414882.4
Homo sapiens (human)	HS3ST2	NP_006034.1
Danio rerio (zebrafish)	hs3st2	NP_001074077.1
	HS3ST2	XP_001093356.1
Rattus norvegicus (Norway rat)	Hs3st2	NP_852035.1
Bos taurus (cattle)	HS3ST2	NP_001192923.1
Xenopus tropicalis (tropical clawed frog)	hs3st2	XP_002932036.2
Pan troglodytes (chimpanzee)	HS3ST2	XP_523317.2
Canis lupus familiaris (dog)	HS3ST2	XP_547095.2

Gene Ontology
Bibliography

Related articles in PubMed

Light-induced 3-O-sulfotransferase expression alters pineal heparan sulfate fine structure. A surprising link to circadian rhythm.
Kuberan B, Lech M, Borjigin J, Rosenberg RD
The Journal of biological chemistry279(7)5053-4(2004 Feb)

Diurnal pineal 3-O-sulphotransferase 2 expression controlled by beta-adrenergic repression.
Borjigin J, Deng J, Sun X, De Jesus M, Liu T, Wang MM
The Journal of biological chemistry278(18)16315-9(2003 May)

Methylation-associated silencing of heparan sulfate D-glucosaminyl 3-O-sulfotransferase-2 (3-OST-2) in human breast, colon, lung and pancreatic cancers.
Miyamoto K, Asada K, Fukutomi T, Okochi E, Yagi Y, Hasegawa T, Asahara T, Sugimura T, Ushijima T
Oncogene22(2)274-80(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

3-O sulfation catalyzed by HS 3-O-sulfotransferase (3-OST2) is predominantly restricted to daytime pineal glands in rats
Title: Light-induced 3-O-sulfotransferase expression alters pineal heparan sulfate fine structure. A surprising link to circadian rhythm.

The following Hs3st2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hs3st2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04269	NM_181370.2 Latest version!	Rattus norvegicus heparan sulfate-glucosamine 3-sulfotransferase 2 (Hs3st2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hs3st2 ( NM_181370.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_852035.1 Rattus norvegicus heparan sulfate-glucosamine 3-sulfotransferase 2 (Hs3st2), mRNA.

Price & Availability↑

CloneID	ORa04269
Clone ID Related Accession (Same CDS sequence)	NM_181370.2
Accession Version	NM_181370.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	heparan sulfate glucosamine 3-O-sulfotransferase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY240873.1. On Jun 3, 2003 this sequence version replaced NM_181370.1. ##Evidence-Data-START## Transcript exon combination :: AY240873.1, BG670456.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTATA GGGTCCTGGG CCGCGCGGGG CCACCTCAGC CGCGGAGAGC GCGCAGGCTG 
CTCTTCGCCT TCACACTGTC CTTGTCCTGC ACTTACCTGT GTTACAGCTT CCTGTGCTGC 
TGCGACGGTC TGGGCCAGAG CCGCCTGCTC GGCGCGCCGC GCTGCCTCCG CGGCCCCAGC 
GCAAGCGGCC AGAAACTTCT GGCGAAGTCC CGCCCGTGTG ATCCCCCGGG GCCGACGCCC 
AGTGAGCCCA GCGCTCCCAG CGCGCCCGCC GCTGCCGCGC CAGCACCGCG CCTCTCCGGA 
TCCAACCACT CTGGCTCCCC GAAGCCAGGC ACCAAACGGC TGCCCCAAGC CCTCATTGTG 
GGCGTTAAGA AAGGTGGTAC CCGAGCAGTG CTGGAGTTTA TCCGAGTGCA CCCGGACGTT 
CGAGCCCTGG GCACCGAGCC CCACTTCTTC GACAGGAATT ACGGCCGAGG GCTGGACTGG 
TACAGGAGCC TGATGCCGAG GACCTTGGAG ACCCAGATCA CACTGGAGAA GACGCCTAGC 
TACTTCGTCA CTCAAGAAGC CCCTCGGAGG ATCTTCAACA TGTCTCGAGA CACCAAGCTG 
ATAGTGGTGG TGCGGAACCC GGTGACCCGA GCCATCTCTG ACTACACGCA GACGCTTTCC 
AAGAAGCCGG ACATCCCCAC CTTCGAGGGC TTGTCCTTCC GCAACCGCAG CCTGGGCCTG 
GTGGATGTGT CTTGGAACGC CATCCGCATC GGCATGTACG CACTGCACCT GGAGAGCTGG 
CTCCGGTACT TCCCGCTGGC CCAGATCCAC TTCGTCAGTG GTGAGCGGCT CATCACCGAC 
CCAGCTGGTG AGATGGGGCG CATTCAGGAC TTCCTGGGCA TCAAGAGATT CATCACAGAC 
AAGCACTTCT ACTTCAACAA GACCAAAGGA TTCCCTTGCT TGAAAAAACC AGAGTCAACC 
CTCCTGCCTC GATGCCTGGG CAAATCAAAA GGGAGAACTC ATGTACAGAT CGACCCTGAA 
GTTATAGACC AGCTCCGGGA ATTTTATAGA CCTTATAATA TTAAATTTTA TGAAACTGTT 
GGGCAGGACT TCCGGTGGGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_852035.1
CDS	440..1543
Translation	MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDGLGQSRLLGAPRCLRGPSASGQKLLAKSRPCDPPGPTPSEPSAPSAPAAAAPAPRLSGSNHSGSPKPGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLETQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRSLGLVDVSWNAIRIGMYALHLESWLRYFPLAQIHFVSGERLITDPAGEMGRIQDFLGIKRFITDKHFYFNKTKGFPCLKKPESTLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE

Target ORF information:

RefSeq Version	NM_181370.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus heparan sulfate-glucosamine 3-sulfotransferase 2 (Hs3st2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181370.2

ORF Insert Sequence:

ATGGCCTATA GGGTCCTGGG CCGCGCGGGG CCACCTCAGC CGCGGAGAGC GCGCAGGCTG 
CTCTTCGCCT TCACACTGTC CTTGTCCTGC ACTTACCTGT GTTACAGCTT CCTGTGCTGC 
TGCGACGGTC TGGGCCAGAG CCGCCTGCTC GGCGCGCCGC GCTGCCTCCG CGGCCCCAGC 
GCAAGCGGCC AGAAACTTCT GGCGAAGTCC CGCCCGTGTG ATCCCCCGGG GCCGACGCCC 
AGTGAGCCCA GCGCTCCCAG CGCGCCCGCC GCTGCCGCGC CAGCACCGCG CCTCTCCGGA 
TCCAACCACT CTGGCTCCCC GAAGCCAGGC ACCAAACGGC TGCCCCAAGC CCTCATTGTG 
GGCGTTAAGA AAGGTGGTAC CCGAGCAGTG CTGGAGTTTA TCCGAGTGCA CCCGGACGTT 
CGAGCCCTGG GCACCGAGCC CCACTTCTTC GACAGGAATT ACGGCCGAGG GCTGGACTGG 
TACAGGAGCC TGATGCCGAG GACCTTGGAG ACCCAGATCA CACTGGAGAA GACGCCTAGC 
TACTTCGTCA CTCAAGAAGC CCCTCGGAGG ATCTTCAACA TGTCTCGAGA CACCAAGCTG 
ATAGTGGTGG TGCGGAACCC GGTGACCCGA GCCATCTCTG ACTACACGCA GACGCTTTCC 
AAGAAGCCGG ACATCCCCAC CTTCGAGGGC TTGTCCTTCC GCAACCGCAG CCTGGGCCTG 
GTGGATGTGT CTTGGAACGC CATCCGCATC GGCATGTACG CACTGCACCT GGAGAGCTGG 
CTCCGGTACT TCCCGCTGGC CCAGATCCAC TTCGTCAGTG GTGAGCGGCT CATCACCGAC 
CCAGCTGGTG AGATGGGGCG CATTCAGGAC TTCCTGGGCA TCAAGAGATT CATCACAGAC 
AAGCACTTCT ACTTCAACAA GACCAAAGGA TTCCCTTGCT TGAAAAAACC AGAGTCAACC 
CTCCTGCCTC GATGCCTGGG CAAATCAAAA GGGAGAACTC ATGTACAGAT CGACCCTGAA 
GTTATAGACC AGCTCCGGGA ATTTTATAGA CCTTATAATA TTAAATTTTA TGAAACTGTT 
GGGCAGGACT TCCGGTGGGA GTGA