Klk1c9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Klk1c9
Entrez Gene ID	292868
Full Name	kallikrein 1-related peptidase C9
Synonyms	Klk9,Klks3,Klna2,rGK-9,rK9
General protein information	Preferred Names kallikrein 1-related peptidase C9 Names submandibular glandular kallikrein-9 KLK-S3 S3 kallikrein SEV kallikrein a2 kallikrein, submaxillary gland S3 submandibular enzymatic vasoconstrictor submaxillary gland S3 kallikrein tissue kallikrein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22
Summary	a kallikrein-related serine protease; first isolated from the rat submaxillary gland; acts as a potent enzymatic vasoconstrictor [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_175759.2	NP_786935.1	submandibular glandular kallikrein-9 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Klk1c2	NP_036809.1
Rattus norvegicus (Norway rat)	Klk1c9	NP_786935.1
Rattus norvegicus (Norway rat)	LOC100911689	XP_003748896.1
Homo sapiens (human)	KLK1	NP_002248.1
Canis lupus familiaris (dog)	KLK1	NP_001003262.1
Rattus norvegicus (Norway rat)	Klk1c7	NP_036725.1
Rattus norvegicus (Norway rat)	Klk1c10	NP_001128645.1
Rattus norvegicus (Norway rat)	LOC100911764	XP_003748897.1
Bos taurus (cattle)	KLK1	NP_001008416.1
Rattus norvegicus (Norway rat)	Klk1	NP_113711.1
Rattus norvegicus (Norway rat)	Klk1c12	NP_001005382.1
Rattus norvegicus (Norway rat)	Klk1c6	NP_001003977.1
Rattus norvegicus (Norway rat)	LOC687880	XP_006229230.1
Rattus norvegicus (Norway rat)	Klk1c8	NP_001013085.1
Rattus norvegicus (Norway rat)	Klk1c3	NP_001258244.1

Gene Ontology
Bibliography

Related articles in PubMed

Klk1 as one of the genes contributing to hypertension in Dahl salt-sensitive rat.
Iwai N, Yasui N, Naraba H, Tago N, Yamawaki H, Sumiya H
Hypertension (Dallas, Tex. : 1979)45(5)947-53(2005 May)

Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.
Olsson AY, Lilja H, Lundwall A
Genomics84(1)147-56(2004 Jul)

The transcriptional regulatory strategy of the rat tissue kallikrein gene family.
Kroon E, MacDonald RJ, Hammer RE
Genes and function1(5-6)309-19(1997 Dec)

A novel serine protease with vasoconstrictor activity coded by the kallikrein gene S3.
Yamaguchi T, Carretero OA, Scicli AG
The Journal of biological chemistry266(8)5011-7(1991 Mar)

Kallikrein-related mRNAs of the rat submaxillary gland: nucleotide sequences of four distinct types including tonin.
Ashley PL, MacDonald RJ
Biochemistry24(17)4512-20(1985 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Klks3 rat gene was expressed at high levels in the submandibular glands of transgenic mice.
Title: The transcriptional regulatory strategy of the rat tissue kallikrein gene family.

The following Klk1c9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Klk1c9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03944	NM_175759.2 Latest version!	Rattus norvegicus kallikrein 1-related peptidase C9 (Klk1c9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Klk1c9 ( NM_175759.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_786935.1 Rattus norvegicus kallikrein 1-related peptidase C9 (Klk1c9), mRNA.

Price & Availability↑

CloneID	ORa03944
Clone ID Related Accession (Same CDS sequence)	NM_175759.2
Accession Version	NM_175759.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	submandibular glandular kallikrein-9 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M11566.1. On Jun 3, 2003 this sequence version replaced NM_175759.1. ##Evidence-Data-START## Transcript exon combination :: M11566.1, BC061771.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMN02642749 [ECO:0000348] ##Evidence-Data-END##

ATGTGGTTCC TGATCCTGTT CCTCGCCCTG TCCCTGGGAC AGATTGATGC TGCACCTCCT 
GGCCAGTCTC GGGTTGTTGG AGGATATAAC TGTGAGACGA ATTCCCAACC CTGGCAAGTG 
GCTGTCATTG GTACAACTTT CTGCGGGGGT GTCCTGATAG ACCCCAGCTG GGTGATCACA 
GCTGCCCACT GCTATAGCAA GAATTATCGT GTTTTGCTGG GCCGAAACAA CCTAGTTAAA 
GATGAACCCT TTGCTCAGCG CCGGCTTGTC AGCCAAAGCT TCCAACACCC TGACTACATC 
CCAGTCTTCA TGAGGAACCA CACCCGACAA CGTGCGTATG ACCACAACAA TGACCTGATG 
CTGCTCCACC TCAGCAAGCC TGCTGACATC ACAGGTGGTG TGAAGGTCAT CGATCTGCCC 
ACTGAGGAGC CCAAAGTGGG GAGCATCTGC CTTGCCTCAG GCTGGGGCAT GACCAACCCC 
TCTGAGATGA AATTAAGTCA TGATCTCCAG TGTGTGAACA TCCACCTTCT GTCTAATGAG 
AAGTGCATCG AAACCTACAA AAACATTGAG ACAGATGTCA CGCTGTGTGC AGGAGAGATG 
GATGGGGGCA AAGACACTTG CACGGGTGAC TCAGGAGGCC CCCTCATCTG TGATGGTGTG 
CTCCAGGGCC TCACATCGGG GGGCGCTACC CCATGCGCTA AACCCAAAAC ACCGGCAATC 
TATGCCAAAC TTATTAAGTT CACCTCCTGG ATAAAAAAAG TTATGAAGGA AAACCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_786935.1
CDS	37..816
Translation	MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP

Target ORF information:

RefSeq Version	NM_175759.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus kallikrein 1-related peptidase C9 (Klk1c9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175759.2

ORF Insert Sequence:

ATGTGGTTCC TGATCCTGTT CCTCGCCCTG TCCCTGGGAC AGATTGATGC TGCACCTCCT 
GGCCAGTCTC GGGTTGTTGG AGGATATAAC TGTGAGACGA ATTCCCAACC CTGGCAAGTG 
GCTGTCATTG GTACAACTTT CTGCGGGGGT GTCCTGATAG ACCCCAGCTG GGTGATCACA 
GCTGCCCACT GCTATAGCAA GAATTATCGT GTTTTGCTGG GCCGAAACAA CCTAGTTAAA 
GATGAACCCT TTGCTCAGCG CCGGCTTGTC AGCCAAAGCT TCCAACACCC TGACTACATC 
CCAGTCTTCA TGAGGAACCA CACCCGACAA CGTGCGTATG ACCACAACAA TGACCTGATG 
CTGCTCCACC TCAGCAAGCC TGCTGACATC ACAGGTGGTG TGAAGGTCAT CGATCTGCCC 
ACTGAGGAGC CCAAAGTGGG GAGCATCTGC CTTGCCTCAG GCTGGGGCAT GACCAACCCC 
TCTGAGATGA AATTAAGTCA TGATCTCCAG TGTGTGAACA TCCACCTTCT GTCTAATGAG 
AAGTGCATCG AAACCTACAA AAACATTGAG ACAGATGTCA CGCTGTGTGC AGGAGAGATG 
GATGGGGGCA AAGACACTTG CACGGGTGAC TCAGGAGGCC CCCTCATCTG TGATGGTGTG 
CTCCAGGGCC TCACATCGGG GGGCGCTACC CCATGCGCTA AACCCAAAAC ACCGGCAATC 
TATGCCAAAC TTATTAAGTT CACCTCCTGG ATAAAAAAAG TTATGAAGGA AAACCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Klk1 as one of the genes contributing to hypertension in Dahl salt-sensitive rat.
Hypertension (Dallas, Tex. : 1979)45(5)947-53(2005 May)
Iwai N,Yasui N,Naraba H,Tago N,Yamawaki H,Sumiya H

Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.
Genomics84(1)147-56(2004 Jul)
Olsson AY,Lilja H,Lundwall A

The transcriptional regulatory strategy of the rat tissue kallikrein gene family.
Genes and function1(5-6)309-19(1997 Dec)
Kroon E,MacDonald RJ,Hammer RE

A novel serine protease with vasoconstrictor activity coded by the kallikrein gene S3.
The Journal of biological chemistry266(8)5011-7(1991 Mar)
Yamaguchi T,Carretero OA,Scicli AG

Kallikrein-related mRNAs of the rat submaxillary gland: nucleotide sequences of four distinct types including tonin.
Biochemistry24(17)4512-20(1985 Aug)
Ashley PL,MacDonald RJ