Shkbp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Shkbp1
Entrez Gene ID	292735
Full Name	Sh3kbp1 binding protein 1
Synonyms	RGD1309281,Sb1
General protein information	Preferred Names Sh3kbp1 binding protein 1 Names SH3KBP1-binding protein 1 SETA-binding protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271080.1	NP_001258009.1	SH3KBP1-binding protein 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Shkbp1	NP_001258009.1
Xenopus tropicalis (tropical clawed frog)	LOC100486587	XP_002938848.1
Pan troglodytes (chimpanzee)	SHKBP1	XP_512668.3
Bos taurus (cattle)	SHKBP1	NP_001076076.1
Mus musculus (house mouse)	Shkbp1	NP_619617.2
Danio rerio (zebrafish)	shkbp1	XP_001920935.4
Homo sapiens (human)	SHKBP1	NP_612401.2
Canis lupus familiaris (dog)	SHKBP1	XP_533665.2

Gene Ontology
Bibliography

Related articles in PubMed

SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex.
Feng L, Wang JT, Jin H, Qian K, Geng JG
Cell biochemistry and function29(7)589-96(2011 Oct)

SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins.
Borinstein SC, Hyatt MA, Sykes VW, Straub RE, Lipkowitz S, Boulter J, Bogler O
Cellular signalling12(11-12)769-79(2000 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Shkbp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Shkbp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10184	NM_001271080.1 Latest version!	Rattus norvegicus Sh3kbp1 binding protein 1 (Shkbp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Shkbp1 ( NM_001271080.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001258009.1 Rattus norvegicus Sh3kbp1 binding protein 1 (Shkbp1), mRNA.

Price & Availability↑

CloneID	ORa10184
Clone ID Related Accession (Same CDS sequence)	NM_001271080.1
Accession Version	NM_001271080.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2115bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	SH3KBP1-binding protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123095.4. On Aug 31, 2012 this sequence version replaced XM_214873.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGTCC CGACGACTGC AGTGGAGGGG GTCCGGAGTC GGGGAGCGCC CGGGGAAGTG 
ATTCATCTGA ACGTAGGGGG CAAGCGGTTC AGCACCTCTC GCCAGACGCT AACCTGGATC 
CCAGACTCCT TCTTTTCCAG TCTTTTGAGC GGACGTATCT CAACCCTGAA AGATGAGACC 
GGAGCCATCT TCATCGACCG GGACCCCACT GTCTTTGCCC CCATCCTCAA TTTCCTGAGG 
ACCAAAGAGT TAGACCCCAG GGGTGTCCAT GGTTCCAGCC TCCTCCATGA AGCCCAATTC 
TATGGGCTCA CTCCACTGGT TCGTCGCCTG CAGGTAAGGG AAGAGTTGGA TCGATCTTCC 
TGCGGAAATG TCCTCTTCAA TGGTTATCTA CCTCCTCCAG TGTTCCCAGT GAAGCGGAGA 
AACCGGCACA GCCTGGTGGG GCCCCAGCAA ATAGGGGGAC GCCCAGCCCC TGTTCGACGG 
AGCAACACGA TGCCCCCCAA CTTGGGTAAT GCAGGGCTGC TAGGCCGAAT GCTGGATGAT 
AGAGCACCTC CATCCCCATC AGGCCAACCA GAGGAACCAG GGATGGTGCG GCTGGTGTGT 
GGTCACCACA ACTGGATTGC TGTGGCGTAT ACCCACTTTC TCGTCTGTTA TAGACTGAAG 
GAAGCCTCCG GTTGGCAGCT TGCATTCTCC AGTCCTCGCC TAGACTGGCC CATTGAGCGC 
CTGGCTCTCA CAGCTCGGGT GCTCGGTGGT GCTCCAGGCG AGCATGACAA GATGGTGGCT 
GCAGCCACAG GCAGCGAGAT CCTTCTGTGG GCGCTACAGG CACAAGGTGG TGGCTCTGAG 
ATAGGTGTCT TCCACCTGGG TGTGCCTGTG GAAGCCTTGT TCTTTGTTGG GAACCAGCTC 
ATTGCCACAA GCCACACAGG GCGCATCGGT GTCTGGAACG CCGTGACCAA GCACTGGCAG 
GTCCAGGAGG TCCAGCCTAT CACGAGTTAT GATGCAGCCG GCTCCTTCCT CCTCCTGGGC 
TGCAGCAATG GCTCCATCTA TTATGTAGAT GTGCAGAAAT TCCCCCTGCG CATGAAGGAC 
AACGACCTCC TTGTCAGTGA GCTCTACCGA GACCCAGCAG AAGATGGGGT CACCGCCCTC 
AGCGTCTACC TCACCCCCAA GACCAGTGAC AGTGGGAACT GGATTGAGAT TGCCTATGGC 
ACCAGCTCCG GAGTGGTGCG GGTCATTGTC CAGCACCCCG AGACAGTGGG CTCGGGACCC 
CAGCTCTTCC AGACCTTCAG TGTACACCGC AGCCCTGTCA CCAAGATCAT GCTGTCAGAG 
AAGCACCTCA TCTCTGTGTG TGCCGACAAC AACCATGTTC GGACGTGGTC TGTGACCCGC 
TTTCGAGGCA TGATCTCCAC CCAGCCTGGT TCCACTCCAC TGGCATCCTT CAAGATCCTG 
GCACTTGAAT CAGCCGATGG GCTCGGTGGC TGCAGTGCTG GCAATGACAT TGGTCCCTAT 
GGTGAGCGGG ATGACCAGCA GGTGTTCATC CAGAAGGTGG TACCAAATGC CAGCCAGCTG 
TTTGTGCGTC TCTCCTCCAC TGGGCAGCGG GTGTGTTCTG TACGCTCAGT GGATGGCTCC 
GCTACGACTG CCTTCACAGT GTTGGAGTGT GAGGGCTCCA GGCGGTTGGG CTCCAGACCC 
CGACGCTACC TGCTCACCGG CCAAGCCAAT GGCAGCCTGG CCATGTGGGA CCTGACCACT 
GCCATGGACG GCCTGGGCCA AACCCCTGCA GGCGGCCTGA CCGAAGAAGA GCTGATGGAC 
CAACTGGAGC AGTGTGAACT GAGCCCATTG ACTTCTTCTC GGGCCTCTTT TCCCAGCCCC 
TCACCCAGAA CCTCTCTTAC CAGTCTACAC TCAGCCTCCA GCAACACCTC GCTGTGTGGC 
CACAGAGGGA GCCCCAGCCC ACCGCAGGCA GGGGCCCGGA GCCGCGGGGC AGGAAGCTTC 
GTGGATCGGT TTAAAGAACT GGCAAGGGGT GCACCGGAGC TCCGAGGGCC ACCAACACCA 
GCCCCTCGAC CCTCCACCAG TCTTGGGAAT CCCCTGATAC TTCCCAAAAA CACACTTAAC 
GAAACTTCCT TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258009.1
CDS	1..2115
Translation	MAVPTTAVEGVRSRGAPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQVREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGPQQIGGRPAPVRRSNTMPPNLGNAGLLGRMLDDRAPPSPSGQPEEPGMVRLVCGHHNWIAVAYTHFLVCYRLKEASGWQLAFSSPRLDWPIERLALTARVLGGAPGEHDKMVAAATGSEILLWALQAQGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCSNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTSDSGNWIEIAYGTSSGVVRVIVQHPETVGSGPQLFQTFSVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESADGLGGCSAGNDIGPYGERDDQQVFIQKVVPNASQLFVRLSSTGQRVCSVRSVDGSATTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQTPAGGLTEEELMDQLEQCELSPLTSSRASFPSPSPRTSLTSLHSASSNTSLCGHRGSPSPPQAGARSRGAGSFVDRFKELARGAPELRGPPTPAPRPSTSLGNPLILPKNTLNETSF

Target ORF information:

RefSeq Version	NM_001271080.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Sh3kbp1 binding protein 1 (Shkbp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271080.1

ORF Insert Sequence:

ATGGCTGTCC CGACGACTGC AGTGGAGGGG GTCCGGAGTC GGGGAGCGCC CGGGGAAGTG 
ATTCATCTGA ACGTAGGGGG CAAGCGGTTC AGCACCTCTC GCCAGACGCT AACCTGGATC 
CCAGACTCCT TCTTTTCCAG TCTTTTGAGC GGACGTATCT CAACCCTGAA AGATGAGACC 
GGAGCCATCT TCATCGACCG GGACCCCACT GTCTTTGCCC CCATCCTCAA TTTCCTGAGG 
ACCAAAGAGT TAGACCCCAG GGGTGTCCAT GGTTCCAGCC TCCTCCATGA AGCCCAATTC 
TATGGGCTCA CTCCACTGGT TCGTCGCCTG CAGGTAAGGG AAGAGTTGGA TCGATCTTCC 
TGCGGAAATG TCCTCTTCAA TGGTTATCTA CCTCCTCCAG TGTTCCCAGT GAAGCGGAGA 
AACCGGCACA GCCTGGTGGG GCCCCAGCAA ATAGGGGGAC GCCCAGCCCC TGTTCGACGG 
AGCAACACGA TGCCCCCCAA CTTGGGTAAT GCAGGGCTGC TAGGCCGAAT GCTGGATGAT 
AGAGCACCTC CATCCCCATC AGGCCAACCA GAGGAACCAG GGATGGTGCG GCTGGTGTGT 
GGTCACCACA ACTGGATTGC TGTGGCGTAT ACCCACTTTC TCGTCTGTTA TAGACTGAAG 
GAAGCCTCCG GTTGGCAGCT TGCATTCTCC AGTCCTCGCC TAGACTGGCC CATTGAGCGC 
CTGGCTCTCA CAGCTCGGGT GCTCGGTGGT GCTCCAGGCG AGCATGACAA GATGGTGGCT 
GCAGCCACAG GCAGCGAGAT CCTTCTGTGG GCGCTACAGG CACAAGGTGG TGGCTCTGAG 
ATAGGTGTCT TCCACCTGGG TGTGCCTGTG GAAGCCTTGT TCTTTGTTGG GAACCAGCTC 
ATTGCCACAA GCCACACAGG GCGCATCGGT GTCTGGAACG CCGTGACCAA GCACTGGCAG 
GTCCAGGAGG TCCAGCCTAT CACGAGTTAT GATGCAGCCG GCTCCTTCCT CCTCCTGGGC 
TGCAGCAATG GCTCCATCTA TTATGTAGAT GTGCAGAAAT TCCCCCTGCG CATGAAGGAC 
AACGACCTCC TTGTCAGTGA GCTCTACCGA GACCCAGCAG AAGATGGGGT CACCGCCCTC 
AGCGTCTACC TCACCCCCAA GACCAGTGAC AGTGGGAACT GGATTGAGAT TGCCTATGGC 
ACCAGCTCCG GAGTGGTGCG GGTCATTGTC CAGCACCCCG AGACAGTGGG CTCGGGACCC 
CAGCTCTTCC AGACCTTCAG TGTACACCGC AGCCCTGTCA CCAAGATCAT GCTGTCAGAG 
AAGCACCTCA TCTCTGTGTG TGCCGACAAC AACCATGTTC GGACGTGGTC TGTGACCCGC 
TTTCGAGGCA TGATCTCCAC CCAGCCTGGT TCCACTCCAC TGGCATCCTT CAAGATCCTG 
GCACTTGAAT CAGCCGATGG GCTCGGTGGC TGCAGTGCTG GCAATGACAT TGGTCCCTAT 
GGTGAGCGGG ATGACCAGCA GGTGTTCATC CAGAAGGTGG TACCAAATGC CAGCCAGCTG 
TTTGTGCGTC TCTCCTCCAC TGGGCAGCGG GTGTGTTCTG TACGCTCAGT GGATGGCTCC 
GCTACGACTG CCTTCACAGT GTTGGAGTGT GAGGGCTCCA GGCGGTTGGG CTCCAGACCC 
CGACGCTACC TGCTCACCGG CCAAGCCAAT GGCAGCCTGG CCATGTGGGA CCTGACCACT 
GCCATGGACG GCCTGGGCCA AACCCCTGCA GGCGGCCTGA CCGAAGAAGA GCTGATGGAC 
CAACTGGAGC AGTGTGAACT GAGCCCATTG ACTTCTTCTC GGGCCTCTTT TCCCAGCCCC 
TCACCCAGAA CCTCTCTTAC CAGTCTACAC TCAGCCTCCA GCAACACCTC GCTGTGTGGC 
CACAGAGGGA GCCCCAGCCC ACCGCAGGCA GGGGCCCGGA GCCGCGGGGC AGGAAGCTTC 
GTGGATCGGT TTAAAGAACT GGCAAGGGGT GCACCGGAGC TCCGAGGGCC ACCAACACCA 
GCCCCTCGAC CCTCCACCAG TCTTGGGAAT CCCCTGATAC TTCCCAAAAA CACACTTAAC 
GAAACTTCCT TTTGA