Pex19 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pex19
Entrez Gene ID	289233
Full Name	peroxisomal biogenesis factor 19
Synonyms	PxF
General protein information	Preferred Names peroxisomal biogenesis factor 19 Names peroxisomal biogenesis factor 19 peroxin-19 peroxisomal farnesylated protein peroxisome biogenesis factor 19
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001134777.1	NP_001128249.1	peroxisomal biogenesis factor 19 isoform 2
NM_001107375.2	NP_001100845.1	peroxisomal biogenesis factor 19 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PEX19	XP_001171920.1
Canis lupus familiaris (dog)	PEX19	XP_536130.2
Mus musculus (house mouse)	Pex19	NP_075528.3
Danio rerio (zebrafish)	pex19	NP_001017399.1
Homo sapiens (human)	PEX19	NP_002848.1
Bos taurus (cattle)	PEX19	NP_001029712.1
Rattus norvegicus (Norway rat)	LOC100911356	XP_003751852.1
Drosophila melanogaster (fruit fly)	Pex19	NP_609547.2
Rattus norvegicus (Norway rat)	Pex19	NP_001100845.1
Rattus norvegicus (Norway rat)	LOC102548286	XP_006255025.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008804	XP_001237621.1
Xenopus tropicalis (tropical clawed frog)	pex19	NP_001120089.1

Gene Ontology
Bibliography

Related articles in PubMed

Peroxisome biogenesis: a novel inducible PEX19 splicing variant is involved in early stages of peroxisome proliferation.
Kinoshita N, Matsuura A, Fujiki Y
Journal of biochemistry161(3)297-308(2017 Mar)

PEX14 is required for microtubule-based peroxisome motility in human cells.
Bharti P, Schliebs W, Schievelbusch T, Neuhaus A, David C, Kock K, Herrmann C, Meyer HE, Wiese S, Warscheid B, Theiss C, Erdmann R
Journal of cell science124(Pt 10)1759-68(2011 May)

The cytosolic domain of PEX3, a protein involved in the biogenesis of peroxisomes, binds membrane lipids.
Pinto MP, Grou CP, Fransen M, S?-Miranda C, Azevedo JE
Biochimica et biophysica acta1793(11)1669-75(2009 Nov)

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
Neufeld C, Filipp FV, Simon B, Neuhaus A, Sch?ller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M
The EMBO journal28(6)745-54(2009 Mar)

The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway.
Matsuzaki T, Fujiki Y
The Journal of cell biology183(7)1275-86(2008 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The PEX19i most likely plays important roles involving the membrane formation at early stages, in prompt response to peroxisome proliferation. Similar types of PEX19 mRNA variants were also elevated in mouse regenerating liver.
Title: Peroxisome biogenesis: a novel inducible PEX19 splicing variant is involved in early stages of peroxisome proliferation.

The following Pex19 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pex19 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03396	NM_001107375.2 Latest version!	Rattus norvegicus peroxisomal biogenesis factor 19 (Pex19), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa03588	NM_001134777.1 Latest version!	Rattus norvegicus peroxisomal biogenesis factor 19 (Pex19), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pex19 ( NM_001107375.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100845.1 Rattus norvegicus peroxisomal biogenesis factor 19 (Pex19), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa03396
Clone ID Related Accession (Same CDS sequence)	NM_001107375.2
Accession Version	NM_001107375.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	peroxisomal biogenesis factor 19 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB718412.1, CK600534.1, CO573662.1, BF543157.1, AI712677.1 and CK838542.1. On Sep 5, 2008 this sequence version replaced NM_001107375.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FN802327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCTG CTGAAGGAGG TTGCGGTGCT GGGGTCGAAG CGGACCGGGA ATTGGAGGAG 
CTTTTGGAAA GTGCTCTTGA TGATTTTGAT AAAGCCAAAC CCTCCCCAGC ACCCTCTCCT 
ACCATCTCGG CCCCCGATGC TTCAGGGCCC CAGAAGAGAT CGCCAGGAGA CACTGCCAAA 
GATGCTCTCT TTGCCTCCCA AGAGAAATTT TTCCAGGAAC TGTTCGACAG TGAGCTGGCT 
TCCCAAGCCA CCGCAGAGTT TGAGAAGGCA ATGAAGGAGC TGGCTGAGGA AGAGCCCCAT 
CTGGTGGAGC AGTTCCAGAA GCTCTCAGAG GCAGCTGGGA GAGTGGGCAG CGATGCAAGT 
TCTCAACAAG AATTTACTTC TTGCCTAAAG GAGACATTAA GTGGGCTAGC CAAAAATGCC 
ACTGACCTTC AGAACGCAGG CATGTCTGAA GAAGAACTGA CAAAAGCCAT GGAAGGGCTG 
GGCATGGATG AAGGAGACGG GGAAGGGAAC ATTCTCCCCA TCATGCAGAG CCTCATGCAG 
AACCTCTTGT CTAAGGATGT ATTGTATCCA TCCCTGAAGG AGATCACCGA AAAGTATCCA 
GAATGGCTAC AGAGTCACCA GGAGTCTATT CCCCCAGAGC AGTTTGAGAA GTATCAGCAG 
CAGCACAGTG TCATGGGCAA AATCTGCGAG CAGTTCGAGG CAGAGACGCC CACAGACAGC 
GAGGCTACTC ACAGGGCTCG CTTTGAGGCG GTACTCGATC TTATGCAGCA GTTACAGGAC 
TTGGGCCACC CTCCGAAAGA GCTGGCTGGG GAGATGCCTC CTGGCCTCAA CTTTGACCTG 
GATGCCCTCA ATCTATCGGG CCCACCAGGT GCTAATGGCG AACAGTGTCT GATCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100845.1
CDS	27..926
Translation	MAAAEGGCGAGVEADRELEELLESALDDFDKAKPSPAPSPTISAPDASGPQKRSPGDTAKDALFASQEKFFQELFDSELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDASSQQEFTSCLKETLSGLAKNATDLQNAGMSEEELTKAMEGLGMDEGDGEGNILPIMQSLMQNLLSKDVLYPSLKEITEKYPEWLQSHQESIPPEQFEKYQQQHSVMGKICEQFEAETPTDSEATHRARFEAVLDLMQQLQDLGHPPKELAGEMPPGLNFDLDALNLSGPPGANGEQCLIM

Target ORF information:

RefSeq Version	NM_001107375.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus peroxisomal biogenesis factor 19 (Pex19), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107375.2

ORF Insert Sequence:

ATGGCGGCTG CTGAAGGAGG TTGCGGTGCT GGGGTCGAAG CGGACCGGGA ATTGGAGGAG 
CTTTTGGAAA GTGCTCTTGA TGATTTTGAT AAAGCCAAAC CCTCCCCAGC ACCCTCTCCT 
ACCATCTCGG CCCCCGATGC TTCAGGGCCC CAGAAGAGAT CGCCAGGAGA CACTGCCAAA 
GATGCTCTCT TTGCCTCCCA AGAGAAATTT TTCCAGGAAC TGTTCGACAG TGAGCTGGCT 
TCCCAAGCCA CCGCAGAGTT TGAGAAGGCA ATGAAGGAGC TGGCTGAGGA AGAGCCCCAT 
CTGGTGGAGC AGTTCCAGAA GCTCTCAGAG GCAGCTGGGA GAGTGGGCAG CGATGCAAGT 
TCTCAACAAG AATTTACTTC TTGCCTAAAG GAGACATTAA GTGGGCTAGC CAAAAATGCC 
ACTGACCTTC AGAACGCAGG CATGTCTGAA GAAGAACTGA CAAAAGCCAT GGAAGGGCTG 
GGCATGGATG AAGGAGACGG GGAAGGGAAC ATTCTCCCCA TCATGCAGAG CCTCATGCAG 
AACCTCTTGT CTAAGGATGT ATTGTATCCA TCCCTGAAGG AGATCACCGA AAAGTATCCA 
GAATGGCTAC AGAGTCACCA GGAGTCTATT CCCCCAGAGC AGTTTGAGAA GTATCAGCAG 
CAGCACAGTG TCATGGGCAA AATCTGCGAG CAGTTCGAGG CAGAGACGCC CACAGACAGC 
GAGGCTACTC ACAGGGCTCG CTTTGAGGCG GTACTCGATC TTATGCAGCA GTTACAGGAC 
TTGGGCCACC CTCCGAAAGA GCTGGCTGGG GAGATGCCTC CTGGCCTCAA CTTTGACCTG 
GATGCCCTCA ATCTATCGGG CCCACCAGGT GCTAATGGCG AACAGTGTCT GATCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pex19 ( NM_001134777.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001128249.1 Rattus norvegicus peroxisomal biogenesis factor 19 (Pex19), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa03588
Clone ID Related Accession (Same CDS sequence)	NM_001134777.1
Accession Version	NM_001134777.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	peroxisomal biogenesis factor 19 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB718412.1, CK600534.1, BQ782704.1 and BE108398.1. On Sep 6, 2008 this sequence version replaced XM_213930.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCTG CTGAAGGAGG TTGCGGTGCT GGGGTCGAAG CGGACCGGGA ATTGGAGGAG 
CTTTTGGAAA GTGCTCTTGA TGATTTTGAT AAAGCCAAAC CCTCCCCAGC ACCCTCTCCT 
ACCATCTCGG CCCCCGATGC TTCAGGGCCC CAGAAGAGAT CGCCAGGAGA CACTGCCAAA 
GATGCTCTCT TTGCCTCCCA AGAGAAATTT TTCCAGGAAC TGTTCGACAG TGAGCTGGCT 
TCCCAAGCCA CCGCAGAGTT TGAGAAGGCA ATGAAGGAGC TGGCTGAGGA AGAGCCCCAT 
CTGGTGGAGC AGTTCCAGAA GCTCTCAGAG GCAGCTGGGA GAGTGGGCAG CGATGCAAGT 
TCTCAACAAG AATTTACTTC TTGCCTAAAG GAGACATTAA GTGGGCTAGC CAAAAATGCC 
ACTGACCTTC AGAACGCAGG CATGTCTGAA GAAGAACTGA CAAAAGCCAT GGAAGGGCTG 
GGCATGGATG AAGGAGACGG GGAAGGGAAC ATTCTCCCCA TCATGCAGAG CCTCATGCAG 
AACCTCTTGT CTAAGGATGT ATTGTATCCA TCCCTGAAGG AGATCACCGA AAAGTATCCA 
GAATGGCTAC AGAGTCACCA GGAGTCTATT CCCCCAGAGC AGTTTGAGAA GTATCAGCAG 
CAGCACAGTG TCATGGGCAA AATCTGCGAG CAGTTCGAGG CAGAGACGCC CACAGACAGC 
GAGGCTACTC ACAGGGCTCG CTTTGAGGCG GTACTCGATC TTATGCAGCA GTTACAGGAC 
TTGGGCCACC CTCCGAAAGA GCTGGCTGGG GAGATGTACA CTGGACCTTC AGGGTCTTTG 
CTGATCCTTC TGGCTGGAAC ACTTTTTCCC AGTGCTCGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128249.1
CDS	27..908
Translation	MAAAEGGCGAGVEADRELEELLESALDDFDKAKPSPAPSPTISAPDASGPQKRSPGDTAKDALFASQEKFFQELFDSELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDASSQQEFTSCLKETLSGLAKNATDLQNAGMSEEELTKAMEGLGMDEGDGEGNILPIMQSLMQNLLSKDVLYPSLKEITEKYPEWLQSHQESIPPEQFEKYQQQHSVMGKICEQFEAETPTDSEATHRARFEAVLDLMQQLQDLGHPPKELAGEMYTGPSGSLLILLAGTLFPSAR

Target ORF information:

RefSeq Version	NM_001134777.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus peroxisomal biogenesis factor 19 (Pex19), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134777.1

ORF Insert Sequence:

ATGGCGGCTG CTGAAGGAGG TTGCGGTGCT GGGGTCGAAG CGGACCGGGA ATTGGAGGAG 
CTTTTGGAAA GTGCTCTTGA TGATTTTGAT AAAGCCAAAC CCTCCCCAGC ACCCTCTCCT 
ACCATCTCGG CCCCCGATGC TTCAGGGCCC CAGAAGAGAT CGCCAGGAGA CACTGCCAAA 
GATGCTCTCT TTGCCTCCCA AGAGAAATTT TTCCAGGAAC TGTTCGACAG TGAGCTGGCT 
TCCCAAGCCA CCGCAGAGTT TGAGAAGGCA ATGAAGGAGC TGGCTGAGGA AGAGCCCCAT 
CTGGTGGAGC AGTTCCAGAA GCTCTCAGAG GCAGCTGGGA GAGTGGGCAG CGATGCAAGT 
TCTCAACAAG AATTTACTTC TTGCCTAAAG GAGACATTAA GTGGGCTAGC CAAAAATGCC 
ACTGACCTTC AGAACGCAGG CATGTCTGAA GAAGAACTGA CAAAAGCCAT GGAAGGGCTG 
GGCATGGATG AAGGAGACGG GGAAGGGAAC ATTCTCCCCA TCATGCAGAG CCTCATGCAG 
AACCTCTTGT CTAAGGATGT ATTGTATCCA TCCCTGAAGG AGATCACCGA AAAGTATCCA 
GAATGGCTAC AGAGTCACCA GGAGTCTATT CCCCCAGAGC AGTTTGAGAA GTATCAGCAG 
CAGCACAGTG TCATGGGCAA AATCTGCGAG CAGTTCGAGG CAGAGACGCC CACAGACAGC 
GAGGCTACTC ACAGGGCTCG CTTTGAGGCG GTACTCGATC TTATGCAGCA GTTACAGGAC 
TTGGGCCACC CTCCGAAAGA GCTGGCTGGG GAGATGTACA CTGGACCTTC AGGGTCTTTG 
CTGATCCTTC TGGCTGGAAC ACTTTTTCCC AGTGCTCGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Peroxisome biogenesis: a novel inducible PEX19 splicing variant is involved in early stages of peroxisome proliferation.
Journal of biochemistry161(3)297-308(2017 Mar)
Kinoshita N,Matsuura A,Fujiki Y

PEX14 is required for microtubule-based peroxisome motility in human cells.
Journal of cell science124(Pt 10)1759-68(2011 May)
Bharti P,Schliebs W,Schievelbusch T,Neuhaus A,David C,Kock K,Herrmann C,Meyer HE,Wiese S,Warscheid B,Theiss C,Erdmann R

The cytosolic domain of PEX3, a protein involved in the biogenesis of peroxisomes, binds membrane lipids.
Biochimica et biophysica acta1793(11)1669-75(2009 Nov)
Pinto MP,Grou CP,Fransen M,S?-Miranda C,Azevedo JE

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
The EMBO journal28(6)745-54(2009 Mar)
Neufeld C,Filipp FV,Simon B,Neuhaus A,Sch?ller N,David C,Kooshapur H,Madl T,Erdmann R,Schliebs W,Wilmanns M,Sattler M

The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway.
The Journal of cell biology183(7)1275-86(2008 Dec)
Matsuzaki T,Fujiki Y