Nhp2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nhp2
Entrez Gene ID	287273
Full Name	NHP2 ribonucleoprotein
Synonyms	Nola2
General protein information	Preferred Names NHP2 ribonucleoprotein Names NHP2 ribonucleoprotein H/ACA ribonucleoprotein complex subunit 2-like nucleolar protein family A, member 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q21

mRNA and Protein(s)

mRNA	Protein	Name
XM_003750818.4	XP_003750866.1	NHP2 ribonucleoprotein isoform X1
NM_001105779.1	NP_001099249.1	NHP2 ribonucleoprotein

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.
Freund A, Zhong FL, Venteicher AS, Meng Z, Veenstra TD, Frydman J, Artandi SE
Cell159(6)1389-403(2014 Dec)

An enhanced H/ACA RNP assembly mechanism for human telomerase RNA.
Egan ED, Collins K
Molecular and cellular biology32(13)2428-39(2012 Jul)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA.
Watkins NJ, Bohnsack MT
Wiley interdisciplinary reviews. RNA3(3)397-414(2012 May-Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nhp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nhp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41791	NM_001105779.1 Latest version!	Rattus norvegicus NHP2 ribonucleoprotein (Nhp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa33007	XM_003750818.4 Latest version!	Rattus norvegicus NHP2 ribonucleoprotein (Nhp2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nhp2 ( NM_001105779.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099249.1 Rattus norvegicus NHP2 ribonucleoprotein (Nhp2), mRNA.

Price & Availability↑

CloneID	ORa41791
Clone ID Related Accession (Same CDS sequence)	NM_001105779.1
Accession Version	NM_001105779.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	NHP2 ribonucleoprotein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 3, 2007 this sequence version replaced XM_213293.3, XM_001071992.1.

ATGACCAAAA TAAAGGTGGT TCCCGAGGAA TCTGAGGCGC AGCTTTACAA ATGCATCAAG 
AAGGCCGTAA AGCAGAAGCA GATTCGTCGC GGGGTGAAGG AAGTTCAGAA ATTTGTCAAC 
AAGGGCGAGA AAGGGATCAT GGTCTTGGCA GGAGATACGT TGCCGATTGA GGTGTACTGC 
CATCTTCCAG TTATGTGCGA GGACCAGAAC TTGCCCTACG TCTATATTCC CTCTAAGACG 
GACTTGGGTG CAGCTACAGG ATCGAAACGT CCCACTTGTG TGATCATGGT GAAGCCCCAT 
GAAGACTATC AGGAGGCCTA TGACAAGTGC CTGGAGGAGG TGCAGGCACT GCCTACACCT 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099249.1
CDS	68..433
Translation	MTKIKVVPEESEAQLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVMCEDQNLPYVYIPSKTDLGAATGSKRPTCVIMVKPHEDYQEAYDKCLEEVQALPTPL

Target ORF information:

RefSeq Version	NM_001105779.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NHP2 ribonucleoprotein (Nhp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105779.1

ORF Insert Sequence:

ATGACCAAAA TAAAGGTGGT TCCCGAGGAA TCTGAGGCGC AGCTTTACAA ATGCATCAAG 
AAGGCCGTAA AGCAGAAGCA GATTCGTCGC GGGGTGAAGG AAGTTCAGAA ATTTGTCAAC 
AAGGGCGAGA AAGGGATCAT GGTCTTGGCA GGAGATACGT TGCCGATTGA GGTGTACTGC 
CATCTTCCAG TTATGTGCGA GGACCAGAAC TTGCCCTACG TCTATATTCC CTCTAAGACG 
GACTTGGGTG CAGCTACAGG ATCGAAACGT CCCACTTGTG TGATCATGGT GAAGCCCCAT 
GAAGACTATC AGGAGGCCTA TGACAAGTGC CTGGAGGAGG TGCAGGCACT GCCTACACCT 
CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nhp2 ( XM_003750818.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_003750866.1 Rattus norvegicus NHP2 ribonucleoprotein (Nhp2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa33007
Clone ID Related Accession (Same CDS sequence)	XM_003750818.4
Accession Version	XM_003750818.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	NHP2 ribonucleoprotein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_003750818.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCAAAA TAAAGGTGGT TCCCGAGGAA TCTGAGGCGC AGGCGGAGGG CTGCAGCGAG 
GAGCGCACGT ACGAAGAGCT GCTGGTCAAC CTGAACCCCA TCGCGCAGCC CCTGGCTTCC 
CGCCGCCTGA CGCGCAAGCT TTACAAATGC ATCAAGAAGG CCGTAAAGCA GAAGCAGATT 
CGTCGCGGGG TGAAGGAAGT TCAGAAATTT GTCAACAAGG GCGAGAAAGG GATCATGGTC 
TTGGCAGGAG ATACGTTGCC GATTGAGGTG TACTGCCATC TTCCAGTTAT GTGCGAGGAC 
CAGAACTTGC CCTACGTCTA TATTCCCTCT AAGACGGACT TGGGTGCAGC TACAGGATCG 
AAACGTCCCA CTTGTGTGAT CATGGTGAAG CCCCATGAAG ACTATCAGGA GGCCTATGAC 
AAGTGCCTGG AGGAGGTGCA GGCACTGCCT ACACCTCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_003750866.1
CDS	75..536
Translation	MTKIKVVPEESEAQAEGCSEERTYEELLVNLNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVMCEDQNLPYVYIPSKTDLGAATGSKRPTCVIMVKPHEDYQEAYDKCLEEVQALPTPL

Target ORF information:

RefSeq Version	XM_003750818.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NHP2 ribonucleoprotein (Nhp2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_003750818.4

ORF Insert Sequence:

ATGACCAAAA TAAAGGTGGT TCCCGAGGAA TCTGAGGCGC AGGCGGAGGG CTGCAGCGAG 
GAGCGCACGT ACGAAGAGCT GCTGGTCAAC CTGAACCCCA TCGCGCAGCC CCTGGCTTCC 
CGCCGCCTGA CGCGCAAGCT TTACAAATGC ATCAAGAAGG CCGTAAAGCA GAAGCAGATT 
CGTCGCGGGG TGAAGGAAGT TCAGAAATTT GTCAACAAGG GCGAGAAAGG GATCATGGTC 
TTGGCAGGAG ATACGTTGCC GATTGAGGTG TACTGCCATC TTCCAGTTAT GTGCGAGGAC 
CAGAACTTGC CCTACGTCTA TATTCCCTCT AAGACGGACT TGGGTGCAGC TACAGGATCG 
AAACGTCCCA CTTGTGTGAT CATGGTGAAG CCCCATGAAG ACTATCAGGA GGCCTATGAC 
AAGTGCCTGG AGGAGGTGCA GGCACTGCCT ACACCTCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.
Cell159(6)1389-403(2014 Dec)
Freund A,Zhong FL,Venteicher AS,Meng Z,Veenstra TD,Frydman J,Artandi SE

An enhanced H/ACA RNP assembly mechanism for human telomerase RNA.
Molecular and cellular biology32(13)2428-39(2012 Jul)
Egan ED,Collins K

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA.
Wiley interdisciplinary reviews. RNA3(3)397-414(2012 May-Jun)
Watkins NJ,Bohnsack MT