Crabp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Crabp1
Entrez Gene ID	25061
Full Name	cellular retinoic acid binding protein 1
General protein information	Preferred Names cellular retinoic acid binding protein 1 Names cellular retinoic acid-binding protein 1 CRABP-I cellular retinoic acid-binding protein I
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q24
Summary	cytosolic protein that binds all-trans retinoic acid and may play a role in neurogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001105716.1	NP_001099186.1	cellular retinoic acid-binding protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CRABP1	NP_004369.1
Bos taurus (cattle)	CRABP1	NP_851371.1
Mus musculus (house mouse)	Crabp1	NP_038524.1
Pan troglodytes (chimpanzee)	CRABP1	XP_001142851.2
	CRABP1	XP_001107715.1
Rattus norvegicus (Norway rat)	Crabp1	NP_001099186.1
Gallus gallus (chicken)	CRABP1	NP_001025710.1
Xenopus tropicalis (tropical clawed frog)	crabp1	XP_002934613.1
Danio rerio (zebrafish)	crabp1b	NP_001001842.1
Danio rerio (zebrafish)	crabp1a	NP_878278.1

Gene Ontology
Bibliography

Related articles in PubMed

A mid-life vitamin A supplementation prevents age-related spatial memory deficits and hippocampal neurogenesis alterations through CRABP-I.
Touyarot K, Bonhomme D, Roux P, Alfos S, Lafen?tre P, Richard E, Higueret P, Pallet V
PloS one8(8)e72101(2013)

Physiological insights into all-trans-retinoic acid biosynthesis.
Napoli JL
Biochimica et biophysica acta1821(1)152-67(2012 Jan)

Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity.
Rocha SF, Lopes SS, Gossler A, Henrique D
Developmental biology328(1)54-65(2009 Apr)

Expression of the cellular retinoic acid binding proteins, type II and type I, in mature rat olfactory epithelium.
Asson-Batres MA, Ahmad O, Smith WB
Cell and tissue research312(1)9-19(2003 Apr)

The NH2-terminal amino acid sequence of cellular retinoic-acid binding protein from rat testis.
Eriksson U, Sundelin J, Rask L, Peterson PA
FEBS letters135(1)70-2(1981 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CRABP-I expression controls the intracellular availability of retinoic acid and may be an important regulator of neuronal differentiation processes in the aged hippocampus.
Title: A mid-life vitamin A supplementation prevents age-related spatial memory deficits and hippocampal neurogenesis alterations through CRABP-I.

both CRABP II and CRABP I proteins and the mRNAs that encode them are present in postnatal rat olfactory epithelium
Title: Expression of the cellular retinoic acid binding proteins, type II and type I, in mature rat olfactory epithelium.

The following Crabp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Crabp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12745	NM_001105716.1 Latest version!	Rattus norvegicus cellular retinoic acid binding protein 1 (Crabp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Crabp1 ( NM_001105716.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099186.1 Rattus norvegicus cellular retinoic acid binding protein 1 (Crabp1), mRNA.

Price & Availability↑

CloneID	ORa12745
Clone ID Related Accession (Same CDS sequence)	NM_001105716.1
Accession Version	NM_001105716.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	cellular retinoic acid-binding protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473975.1. On or before Oct 3, 2007 this sequence version replaced XM_001072647.1, XM_236253.3. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCCAACT TCGCCGGTAC CTGGAAGATG CGCAGCAGCG AGAATTTCGA CGAGCTCCTC 
AAGGCTCTGG GTGTGAACGC CATGCTGAGG AAGGTGGCAG TGGCGGCTGC GTCCAAGCCG 
CACGTGGAGA TCCGCCAGGA CGGGGATCAG TTCTACATCA AGACATCCAC TACGGTGCGC 
ACCACGGAGA TCAACTTCAA GGTCGGAGAG GGCTTCGAGG AGGAGACGGT GGACGGACGC 
AAGTGCAGGA GTTTACCCAC TTGGGAGAAT GAGAACAAGA TTCACTGCAC GCAGACGCTT 
CTTGAGGGGG ATGGCCCCAA AACTTACTGG ACCCGAGAGC TGGCCAACGA TGAGCTAATC 
CTGACATTTG GCGCCGATGA TGTGGTGTGC ACAAGAATTT ATGTCCGGGA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099186.1
CDS	108..521
Translation	MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKVGEGFEEETVDGRKCRSLPTWENENKIHCTQTLLEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE

Target ORF information:

RefSeq Version	NM_001105716.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cellular retinoic acid binding protein 1 (Crabp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105716.1

ORF Insert Sequence:

ATGCCCAACT TCGCCGGTAC CTGGAAGATG CGCAGCAGCG AGAATTTCGA CGAGCTCCTC 
AAGGCTCTGG GTGTGAACGC CATGCTGAGG AAGGTGGCAG TGGCGGCTGC GTCCAAGCCG 
CACGTGGAGA TCCGCCAGGA CGGGGATCAG TTCTACATCA AGACATCCAC TACGGTGCGC 
ACCACGGAGA TCAACTTCAA GGTCGGAGAG GGCTTCGAGG AGGAGACGGT GGACGGACGC 
AAGTGCAGGA GTTTACCCAC TTGGGAGAAT GAGAACAAGA TTCACTGCAC GCAGACGCTT 
CTTGAGGGGG ATGGCCCCAA AACTTACTGG ACCCGAGAGC TGGCCAACGA TGAGCTAATC 
CTGACATTTG GCGCCGATGA TGTGGTGTGC ACAAGAATTT ATGTCCGGGA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A mid-life vitamin A supplementation prevents age-related spatial memory deficits and hippocampal neurogenesis alterations through CRABP-I.
PloS one8(8)e72101(2013)
Touyarot K,Bonhomme D,Roux P,Alfos S,Lafen?tre P,Richard E,Higueret P,Pallet V

Physiological insights into all-trans-retinoic acid biosynthesis.
Biochimica et biophysica acta1821(1)152-67(2012 Jan)
Napoli JL

Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity.
Developmental biology328(1)54-65(2009 Apr)
Rocha SF,Lopes SS,Gossler A,Henrique D

Expression of the cellular retinoic acid binding proteins, type II and type I, in mature rat olfactory epithelium.
Cell and tissue research312(1)9-19(2003 Apr)
Asson-Batres MA,Ahmad O,Smith WB

The NH2-terminal amino acid sequence of cellular retinoic-acid binding protein from rat testis.
FEBS letters135(1)70-2(1981 Nov)
Eriksson U,Sundelin J,Rask L,Peterson PA