Prm1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prm1
Entrez Gene ID	24685
Full Name	protamine 1
General protein information	Preferred Names protamine 1 Names sperm protamine P1 cysteine-rich protamine protamine P1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q11
Summary	mouse homolog associates with sperm chromatin during spermatogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001002850.1	NP_001002850.1	sperm protamine P1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Role of follitropin receptor signaling in nuclear protein transitions and chromatin condensation during spermatogenesis.
Xing W, Krishnamurthy H, Sairam MR
Biochemical and biophysical research communications312(3)697-701(2003 Dec)

Haploinsufficiency of protamine-1 or -2 causes infertility in mice.
Cho C, Willis WD, Goulding EH, Jung-Ha H, Choi YC, Hecht NB, Eddy EM
Nature genetics28(1)82-6(2001 May)

A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells.
Zhong J, Peters AH, Lee K, Braun RE
Nature genetics22(2)171-4(1999 Jun)

Sequence analysis of the conserved protamine gene cluster shows that it contains a fourth expressed gene.
Schl?ter G, Celik A, Obata R, Schlicker M, Hofferbert S, Schlung A, Adham IM, Engel W
Molecular reproduction and development43(1)1-6(1996 Jan)

Premature translation of protamine 1 mRNA causes precocious nuclear condensation and arrests spermatid differentiation in mice.
Lee K, Haugen HS, Clegg CH, Braun RE
Proceedings of the National Academy of Sciences of the United States of America92(26)12451-5(1995 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Prm1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prm1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09824	NM_001002850.1 Latest version!	Rattus norvegicus protamine 1 (Prm1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prm1 ( NM_001002850.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001002850.1 Rattus norvegicus protamine 1 (Prm1), mRNA.

Price & Availability↑

CloneID	ORa09824
Clone ID Related Accession (Same CDS sequence)	NM_001002850.1
Accession Version	NM_001002850.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 156bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	sperm protamine P1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z46939.1. ##Evidence-Data-START## Transcript exon combination :: BC126070.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689595, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END##

1
61
121

ATGGCCAGAT ACCGATGCTG CCGCAGCAAA AGCAGGAGCA GATGCCGCCG CCGCAGGCGA 
AGATGTCGCA GACGGAGGAG GCGGTGCTGC AGGCGGAGGC GGCGAAGGTG CTGCCGCCGC 
CGCCGCTCAT ACACCTTTAG GTGTAAAAGA TACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002850.1
CDS	1..156
Translation	MARYRCCRSKSRSRCRRRRRRCRRRRRRCCRRRRRRCCRRRRSYTFRCKRY

Target ORF information:

RefSeq Version	NM_001002850.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protamine 1 (Prm1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002850.1

ORF Insert Sequence:

1
61
121

ATGGCCAGAT ACCGATGCTG CCGCAGCAAA AGCAGGAGCA GATGCCGCCG CCGCAGGCGA 
AGATGTCGCA GACGGAGGAG GCGGTGCTGC AGGCGGAGGC GGCGAAGGTG CTGCCGCCGC 
CGCCGCTCAT ACACCTTTAG GTGTAAAAGA TACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of follitropin receptor signaling in nuclear protein transitions and chromatin condensation during spermatogenesis.
Biochemical and biophysical research communications312(3)697-701(2003 Dec)
Xing W,Krishnamurthy H,Sairam MR

Haploinsufficiency of protamine-1 or -2 causes infertility in mice.
Nature genetics28(1)82-6(2001 May)
Cho C,Willis WD,Goulding EH,Jung-Ha H,Choi YC,Hecht NB,Eddy EM

A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells.
Nature genetics22(2)171-4(1999 Jun)
Zhong J,Peters AH,Lee K,Braun RE

Sequence analysis of the conserved protamine gene cluster shows that it contains a fourth expressed gene.
Molecular reproduction and development43(1)1-6(1996 Jan)
Schl?ter G,Celik A,Obata R,Schlicker M,Hofferbert S,Schlung A,Adham IM,Engel W

Premature translation of protamine 1 mRNA causes precocious nuclear condensation and arrests spermatid differentiation in mice.
Proceedings of the National Academy of Sciences of the United States of America92(26)12451-5(1995 Dec)
Lee K,Haugen HS,Clegg CH,Braun RE