Nat8b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nat8b
Entrez Gene ID	171084
Full Name	N-acetyltransferase 8B
Synonyms	Cml1,Cml6,Nat8,RGD621605
General protein information	Preferred Names N-acetyltransferase 8B Names probable N-acetyltransferase CML6 camello-like 1 like camello-like protein 1 camello-like protein 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q34
Summary	may act as an N-acetyltransferase; Xenopus laevis homolog camello inhibits gastrulation and may regulate cell surface adhesion [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133558.1	NP_598242.1	probable N-acetyltransferase CML6

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Nat8b	NP_598242.1
Rattus norvegicus (Norway rat)	LOC100910982	XP_006236873.1
Danio rerio (zebrafish)	LOC100002956	XP_001342614.1
Xenopus tropicalis (tropical clawed frog)	nat8b	NP_001096360.1

Gene Ontology
Bibliography

Related articles in PubMed

Post-translational regulation of CD133 by ATase1/ATase2-mediated lysine acetylation.
Mak AB, Pehar M, Nixon AM, Williams RA, Uetrecht AC, Puglielli L, Moffat J
Journal of molecular biology426(11)2175-82(2014 May)

Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels.
Ko MH, Puglielli L
The Journal of biological chemistry284(4)2482-92(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nat8b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nat8b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00931	NM_133558.1 Latest version!	Rattus norvegicus N-acetyltransferase 8B (Nat8b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nat8b ( NM_133558.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_598242.1 Rattus norvegicus N-acetyltransferase 8B (Nat8b), mRNA.

Price & Availability↑

CloneID	ORa00931
Clone ID Related Accession (Same CDS sequence)	NM_133558.1
Accession Version	NM_133558.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	probable N-acetyltransferase CML6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF163318.1. ##Evidence-Data-START## Transcript exon combination :: AF163318.1, BC081733.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGTTTCTT ATCACATCTG CGAGTACCAA GACAGCGACT ATAAAAGTGT TGTGGATGTG 
TTTACCAAGG GTGCAGAAGA GTACATCCCC TCCACCTTCC GCCACTTGCT GCTGCTGCCC 
CGAACCCTCC TACTCTTACT TGGGGTGTCC CTTGCCCTGG TCCTGGTGTC TGGCTCCTGG 
CTGCTGGCTG TTGTATGCAT CTTTTTTCTG CTCCCATTTT TGTGGTTCCT TGCTGGACAG 
CCCTGGAAGA ATTATGTGTC CAAATGTTTA CACACAGATA TGGCTGACAT CACCAAGTCT 
TATCTGAGTG ATCGTGGCTC AGGTTTCTGG GTGGCTGAGT CTGGGGAGCA GGTAGTGGGC 
ACAGTGGGTG CTCTGCCAGT CAAGGAGCCT CCATCAGGGA GGAAGCAGTT GCAGCTCTTC 
CACCTGGCTG TGTCCTCACA GCATCGAGGA CAGGGGATAG CGAAAGCACT GGTCAGAACT 
GTGCTCCAGT TTGCACGGGA CCAGGGCTAC ACTGATGTTG TCCTTGAGAC TAGCACCATG 
CAGATAGGTG CTGTGACCCT CTACCTGGGC ATGGGTTTCC AGAAGACAGG CCAATACTTC 
CCGAGTATGC TCTGGAGGTT AGTGGGTATT CGTTTTGTTC AACTAAATTA CTCCTTCCCT 
TCTGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598242.1
CDS	132..800
Translation	MVSYHICEYQDSDYKSVVDVFTKGAEEYIPSTFRHLLLLPRTLLLLLGVSLALVLVSGSWLLAVVCIFFLLPFLWFLAGQPWKNYVSKCLHTDMADITKSYLSDRGSGFWVAESGEQVVGTVGALPVKEPPSGRKQLQLFHLAVSSQHRGQGIAKALVRTVLQFARDQGYTDVVLETSTMQIGAVTLYLGMGFQKTGQYFPSMLWRLVGIRFVQLNYSFPSA

Target ORF information:

RefSeq Version	NM_133558.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus N-acetyltransferase 8B (Nat8b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133558.1

ORF Insert Sequence:

ATGGTTTCTT ATCACATCTG CGAGTACCAA GACAGCGACT ATAAAAGTGT TGTGGATGTG 
TTTACCAAGG GTGCAGAAGA GTACATCCCC TCCACCTTCC GCCACTTGCT GCTGCTGCCC 
CGAACCCTCC TACTCTTACT TGGGGTGTCC CTTGCCCTGG TCCTGGTGTC TGGCTCCTGG 
CTGCTGGCTG TTGTATGCAT CTTTTTTCTG CTCCCATTTT TGTGGTTCCT TGCTGGACAG 
CCCTGGAAGA ATTATGTGTC CAAATGTTTA CACACAGATA TGGCTGACAT CACCAAGTCT 
TATCTGAGTG ATCGTGGCTC AGGTTTCTGG GTGGCTGAGT CTGGGGAGCA GGTAGTGGGC 
ACAGTGGGTG CTCTGCCAGT CAAGGAGCCT CCATCAGGGA GGAAGCAGTT GCAGCTCTTC 
CACCTGGCTG TGTCCTCACA GCATCGAGGA CAGGGGATAG CGAAAGCACT GGTCAGAACT 
GTGCTCCAGT TTGCACGGGA CCAGGGCTAC ACTGATGTTG TCCTTGAGAC TAGCACCATG 
CAGATAGGTG CTGTGACCCT CTACCTGGGC ATGGGTTTCC AGAAGACAGG CCAATACTTC 
CCGAGTATGC TCTGGAGGTT AGTGGGTATT CGTTTTGTTC AACTAAATTA CTCCTTCCCT 
TCTGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Post-translational regulation of CD133 by ATase1/ATase2-mediated lysine acetylation.
Journal of molecular biology426(11)2175-82(2014 May)
Mak AB,Pehar M,Nixon AM,Williams RA,Uetrecht AC,Puglielli L,Moffat J

Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels.
The Journal of biological chemistry284(4)2482-92(2009 Jan)
Ko MH,Puglielli L