Psmc3ip cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Psmc3ip
Entrez Gene ID	140938
Full Name	PSMC3 interacting protein
Synonyms	Gt198,Tbpip
General protein information	Preferred Names PSMC3 interacting protein Names homologous-pairing protein 2 homolog nuclear receptor coactivator GT198 proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein proteasome 26S ATPase subunit 3-interacting protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31
Summary	interacts with nuclear receptors, estrogen receptor alpha and beta, thyroid hormone receptor beta1, androgen receptor, glucocorticoid receptor, and progesterone receptor [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_134458.2	NP_604453.2	homologous-pairing protein 2 homolog
XM_006247249.3	XP_006247311.1	homologous-pairing protein 2 homolog isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LOC789362	XP_005220859.1
Mus musculus (house mouse)	Psmc3ip	NP_032975.1
Homo sapiens (human)	PSMC3IP	NP_057640.1
	LOC710658	XP_002808173.1
Rattus norvegicus (Norway rat)	Psmc3ip	NP_604453.2
Xenopus tropicalis (tropical clawed frog)	psmc3ip	NP_001124002.1
Pan troglodytes (chimpanzee)	PSMC3IP	XP_001164255.1
Arabidopsis thaliana (thale cress)	AHP2	NP_172791.1
Canis lupus familiaris (dog)	PSMC3IP	XP_005624503.1
Danio rerio (zebrafish)	psmc3ip	NP_001002124.1

Gene Ontology
Bibliography

Related articles in PubMed

XX ovarian dysgenesis is caused by a PSMC3IP/HOP2 mutation that abolishes coactivation of estrogen-driven transcription.
Zangen D, Kaufman Y, Zeligson S, Perlberg S, Fridman H, Kanaan M, Abdulhadi-Atwan M, Abu Libdeh A, Gussow A, Kisslov I, Carmel L, Renbaum P, Levy-Lahad E
American journal of human genetics89(4)572-9(2011 Oct)

Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors.
Ko L, Cardona GR, Henrion-Caude A, Chin WW
Molecular and cellular biology22(1)357-69(2002 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Psmc3ip gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Psmc3ip cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01426	NM_134458.2 Latest version!	Rattus norvegicus PSMC3 interacting protein (Psmc3ip), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa33640	XM_006247249.3 Latest version!	Rattus norvegicus PSMC3 interacting protein (Psmc3ip), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Psmc3ip ( NM_134458.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_604453.2 Rattus norvegicus PSMC3 interacting protein (Psmc3ip), mRNA.

Price & Availability↑

CloneID	ORa01426
Clone ID Related Accession (Same CDS sequence)	NM_134458.2
Accession Version	NM_134458.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	homologous-pairing protein 2 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF352812.1 and CK840952.1. On Oct 13, 2005 this sequence version replaced NM_134458.1. ##Evidence-Data-START## Transcript exon combination :: AF352812.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGTAAAA GCCGGGCCGA AGCTGCGGCT GGAGCCCCCG GGATCGTCCT AAGGTACCTG 
CAGGAACAAA ACCGGCCCTA CAGCGCCCAG GACGTGTTCG GGAACCTGCA GAAGGAACAT 
GGACTGGGCA AGGCGGCGGT GGTGAAGGCA CTCGATCAGC TGGCCCAGCA AGGCAAGATC 
AAAGAGAAGA CTTACGGCAA GCAGAAGATA TATTTTGCCG ATCAGGACCA GTTTGACACA 
GTGAGTGATG CGGACCTCCA CAGTCTGGAT GCCAGTATCA TGGCCCTCAC TGCCAAGGTG 
CAGGGCTTAC AGCAGAGCTG CCGGCACATG GAGGCTGAGC TGAAGGAATT AACAAGTGCG 
CTGACCACTC CTGAGATGCA GACAGAGATT CAGGAGTTGA AGAAGGAGTG TGCTCGCTAC 
ACAGAGAGAC TGAAAAACAT CAAAGCAGCT ACCAACCATG TCACTCCAGA AGAGAAGGAG 
AAGGTGTACA GGGAGAGACA GAAGTACTGT AAAGAGTGGA GGAAGCGGAA GAGAATGACC 
ACAGAGCTGT GCGATGCGAT CCTTGAAGGT TACCCCAAGA GCAAGAAGCA GTTCTTTGAA 
GAAGTTGGGA TAGAGACAGA TGAAGATCAT AATGTTACGC TCCCAGACCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_604453.2
CDS	23..676
Translation	MSKSRAEAAAGAPGIVLRYLQEQNRPYSAQDVFGNLQKEHGLGKAAVVKALDQLAQQGKIKEKTYGKQKIYFADQDQFDTVSDADLHSLDASIMALTAKVQGLQQSCRHMEAELKELTSALTTPEMQTEIQELKKECARYTERLKNIKAATNHVTPEEKEKVYRERQKYCKEWRKRKRMTTELCDAILEGYPKSKKQFFEEVGIETDEDHNVTLPDP

Target ORF information:

RefSeq Version	NM_134458.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PSMC3 interacting protein (Psmc3ip), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134458.2

ORF Insert Sequence:

ATGAGTAAAA GCCGGGCCGA AGCTGCGGCT GGAGCCCCCG GGATCGTCCT AAGGTACCTG 
CAGGAACAAA ACCGGCCCTA CAGCGCCCAG GACGTGTTCG GGAACCTGCA GAAGGAACAT 
GGACTGGGCA AGGCGGCGGT GGTGAAGGCA CTCGATCAGC TGGCCCAGCA AGGCAAGATC 
AAAGAGAAGA CTTACGGCAA GCAGAAGATA TATTTTGCCG ATCAGGACCA GTTTGACACA 
GTGAGTGATG CGGACCTCCA CAGTCTGGAT GCCAGTATCA TGGCCCTCAC TGCCAAGGTG 
CAGGGCTTAC AGCAGAGCTG CCGGCACATG GAGGCTGAGC TGAAGGAATT AACAAGTGCG 
CTGACCACTC CTGAGATGCA GACAGAGATT CAGGAGTTGA AGAAGGAGTG TGCTCGCTAC 
ACAGAGAGAC TGAAAAACAT CAAAGCAGCT ACCAACCATG TCACTCCAGA AGAGAAGGAG 
AAGGTGTACA GGGAGAGACA GAAGTACTGT AAAGAGTGGA GGAAGCGGAA GAGAATGACC 
ACAGAGCTGT GCGATGCGAT CCTTGAAGGT TACCCCAAGA GCAAGAAGCA GTTCTTTGAA 
GAAGTTGGGA TAGAGACAGA TGAAGATCAT AATGTTACGC TCCCAGACCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psmc3ip ( XM_006247249.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247311.1 Rattus norvegicus PSMC3 interacting protein (Psmc3ip), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa33640
Clone ID Related Accession (Same CDS sequence)	XM_006247249.3
Accession Version	XM_006247249.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	homologous-pairing protein 2 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247249.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTAAAA GCCGGGCCGA AGCTGCGGCT GGAGCCCCCG GGATCGTCCT AAGGTACCTG 
CAGGAACAAA ACCGGCCCTA CAGCGCCCAG GACGTGTTCG GGAACCTGCA GAAGGAACAT 
GGACTGGGCA AGGCGGCGGT GGTGAAGGCA CTCGATCAGC TGGCCCAGCA AGGCAAGATC 
AAAGAGAAGA CTTACGGCAA GCAGAAGATA TATTTTGCCG ATCAGGACCA GTTTGACACA 
GTGAGTGATG CGGACCTCCA CAGTCTGGAT GCCAGTATCA TGGCCCTCAC TGCCAAGGTG 
CAGGGCTTAC AGCAGAGCTG CCGGCACATG GAGGCTGAGC TGAAGGAATT AACAAGTGCG 
CTGACCACTC CTGAGATGCA GACAGAGATT CAGGAGTTGA AGGAGGAGTG TGCTCGCTAC 
ACAGAGAGAC TGAAAAACAT CAAAGCAGCT ACCAACCATG TCACTCCAGA AGAGAAGGAG 
AAGGTGTACA GGGAGAGACA GAAGTACTGT AAAGAGTGGA GGAAGCGGAA GAGAATGACC 
ACAGAGCTGT GCGATGCGAT CCTTGAAGGT TACCCCAAGA GCAAGAAGCA GTTCTTTGTA 
AGTGACTTTC CTCTCTTGCT CCCCTGGGAT CTTTGCCCAG GGGACTCTTC ACTGCTTTCC 
TTTCACAGGA AGAAGTTGGG ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247311.1
CDS	885..1568
Translation	MSKSRAEAAAGAPGIVLRYLQEQNRPYSAQDVFGNLQKEHGLGKAAVVKALDQLAQQGKIKEKTYGKQKIYFADQDQFDTVSDADLHSLDASIMALTAKVQGLQQSCRHMEAELKELTSALTTPEMQTEIQELKEECARYTERLKNIKAATNHVTPEEKEKVYRERQKYCKEWRKRKRMTTELCDAILEGYPKSKKQFFVSDFPLLLPWDLCPGDSSLLSFHRKKLG

Target ORF information:

RefSeq Version	XM_006247249.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PSMC3 interacting protein (Psmc3ip), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247249.3

ORF Insert Sequence:

ATGAGTAAAA GCCGGGCCGA AGCTGCGGCT GGAGCCCCCG GGATCGTCCT AAGGTACCTG 
CAGGAACAAA ACCGGCCCTA CAGCGCCCAG GACGTGTTCG GGAACCTGCA GAAGGAACAT 
GGACTGGGCA AGGCGGCGGT GGTGAAGGCA CTCGATCAGC TGGCCCAGCA AGGCAAGATC 
AAAGAGAAGA CTTACGGCAA GCAGAAGATA TATTTTGCCG ATCAGGACCA GTTTGACACA 
GTGAGTGATG CGGACCTCCA CAGTCTGGAT GCCAGTATCA TGGCCCTCAC TGCCAAGGTG 
CAGGGCTTAC AGCAGAGCTG CCGGCACATG GAGGCTGAGC TGAAGGAATT AACAAGTGCG 
CTGACCACTC CTGAGATGCA GACAGAGATT CAGGAGTTGA AGGAGGAGTG TGCTCGCTAC 
ACAGAGAGAC TGAAAAACAT CAAAGCAGCT ACCAACCATG TCACTCCAGA AGAGAAGGAG 
AAGGTGTACA GGGAGAGACA GAAGTACTGT AAAGAGTGGA GGAAGCGGAA GAGAATGACC 
ACAGAGCTGT GCGATGCGAT CCTTGAAGGT TACCCCAAGA GCAAGAAGCA GTTCTTTGTA 
AGTGACTTTC CTCTCTTGCT CCCCTGGGAT CTTTGCCCAG GGGACTCTTC ACTGCTTTCC 
TTTCACAGGA AGAAGTTGGG ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

XX ovarian dysgenesis is caused by a PSMC3IP/HOP2 mutation that abolishes coactivation of estrogen-driven transcription.
American journal of human genetics89(4)572-9(2011 Oct)
Zangen D,Kaufman Y,Zeligson S,Perlberg S,Fridman H,Kanaan M,Abdulhadi-Atwan M,Abu Libdeh A,Gussow A,Kisslov I,Carmel L,Renbaum P,Levy-Lahad E

Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors.
Molecular and cellular biology22(1)357-69(2002 Jan)
Ko L,Cardona GR,Henrion-Caude A,Chin WW