LMOD2 cDNA ORF clone, Pelodiscus sinensis(Chinese soft-shelled turtle)

Gene
Clones
gRNAs

Summary

Gene Symbol	LMOD2
Entrez Gene ID	102457699
Full Name	leiomodin 2
Gene Type	protein-coding
Organism	Pelodiscus sinensis(Chinese soft-shelled turtle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_006122591.2	XP_006122653.1	leiomodin-2
XM_006122591.3	XP_006122653.1	leiomodin-2

Pathways from BioSystems
Gene Ontology

The following LMOD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LMOD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OPe28908	XM_006122591.3 Latest version!	Pelodiscus sinensis leiomodin 2 (LMOD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$342.30 $489.00
View Old Accession Versions >>
OPe28908	XM_006122591.2	Pelodiscus sinensis leiomodin 2 (cardiac) (LMOD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$342.30 $489.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LMOD2 ( XM_006122591.2 ) cDNA ORF clone, Pelodiscus sinensis(Chinese soft-shelled turtle) -> XP_006122653.1 Pelodiscus sinensis leiomodin 2 (cardiac) (LMOD2), mRNA.

Price & Availability↑

CloneID	OPe28908
Clone ID Related Accession (Same CDS sequence)	XM_006122591.2 , XM_006122591.3
Accession Version	XM_006122591.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-11-02
Organism	Pelodiscus sinensis(Chinese soft-shelled turtle)
Product	leiomodin-2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_005855045.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Nov 3, 2015 this sequence version replaced XM_006122591.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Pelodiscus sinensis Annotation Release 101 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGACCT TTGGCTATAG AAGAGAGCTT AGTAAATATG AATCCATTGA TGAAGATGAA 
CTCCTCGCTT CTCTGACTGA TGAGGAGCTA AAGGAACTGG AAAGGGAACT AGAAGATATT 
GAGCCTGACC GTAACCTTCC AGTGGGGCAG CGACAAAAGA ATTTAACAGA GAAAACGCCA 
ACAGGAACTT TTAGCAGGGA AGCGTTGATG GCCTATTGGG AAAAAGAGAC CAGAAAACTC 
CTAGAAAAAG AAAGGTTGGG GGCGTGTGAA CAGGATTCAA AGCAAGACGA CAACAATTCA 
GAAGAGACCG AGGAAGAGTA TTTCACAGGA ACTAACAGTG AAATTTCTGA GGAGGTATAC 
ACTGAAGAGG AAGAGGAAGA GGAAGCAGAA GAAAAAGAAG AAGAAAAAGA GGAGGAGGAG 
GAAGAAGAAG AAGGAGACAG GGATGAAGGT GACTCAGAAA AAAAGGAAAA TGCTGCAGTT 
TGTGAAAGGA CTGTGACTTG TGAAAGTGGC AGGAGTTCTG ACCACTCCGA ACACAAGAAA 
TGCAACAGCC AAAAGGAAAA GGAAAAGGAA AATGTCATCA ATGGCAATGA CACAGAAGAT 
ATGAGCTTTA AAACAAGTGC CACCCACCTT TGTGGAAACC CAACGGTTAT TGAGGATACT 
TTGGAAAAAG TTCAGAACAA TGACCCTGAC ACCACTGAAG TCAACTTAAA TAACATTGAA 
AACATCACCA TACAGATGCT TACTCATTTC GCGCAAGCGC TCAAGAACAA CACAGTGGTT 
AAGATGTTCA ATCTGGCCAA TACTCGTGCT GATGATAATG CGGCAATTGC TATTGCTGGG 
ATGTTAAAAG TGAATCAGTA TATAACGAGT CTGAATGTAG ATTCAAATTT TATTACCGGC 
AAAGGGATAC TGTCCATCAT GAGAGCTTTG CAGCATAACA AGATTTTAAC AGAACTACGA 
TTCCACAACC AACGGCATAT CATGGGCAGT CAGGTTGAAA TGGACATTGT TAAACTGTTA 
AAAGACAATA CCACATTGGT GAAGCTAGGG TATCATTTTG AGCTTGCTGG ACCAAGAATG 
AGTATGACTA GTATTCTCAC AAGAAACATG GATAAACAAC GGCAAAAACG TATGCAGGAG 
CAAAAACAGC AAGAGTCTGG TTGTAATGGA GCAATCAATC CAAAGACCAA AGCCTTGCAG 
AAAGACACTC TTGGGTCCTC ACCTTACACA TCCCCTAAGA ACTCACCTTG GTCCTCTCCA 
AAACTTCCTA AAAAAGCTCA GCCTGCCAAA AGCCAGCCTC TGGCTCCTCC TTCACCCCCT 
CCTCCTCCTT CCCCACCTCC TCCTCCTCCT CCTCCTCTCA TTGTTCCAGA GAAGAAGGCA 
CCAACTAGGG GTATAGCTGA AGTCATCAAA CAACAAGAGA GCTCCAGGAA TACCTTACAA 
AATGGACACA AAAAGAAAAA AGGCAAAAAA AGCAAAAAGC ATGAAAATAG CATATTGAAA 
GAAATTAAAA ATTCCTTGAG ATCAGTCTCA GACAAGAAAT CAGAAGAAGG ATCACAACCC 
TCTACTCGGC CCTCCACCCC ACAAATATCT CTTCATGATA GCCTTATGGA AGCAATTCGC 
GGAAGCAATA TAAAACAGTT AAAGCGGGTG GAAGTGCCAG AAGCTCTTCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006122653.1
CDS	139..1812
Translation	MSTFGYRRELSKYESIDEDELLASLTDEELKELERELEDIEPDRNLPVGQRQKNLTEKTPTGTFSREALMAYWEKETRKLLEKERLGACEQDSKQDDNNSEETEEEYFTGTNSEISEEVYTEEEEEEEAEEKEEEKEEEEEEEEGDRDEGDSEKKENAAVCERTVTCESGRSSDHSEHKKCNSQKEKEKENVINGNDTEDMSFKTSATHLCGNPTVIEDTLEKVQNNDPDTTEVNLNNIENITIQMLTHFAQALKNNTVVKMFNLANTRADDNAAIAIAGMLKVNQYITSLNVDSNFITGKGILSIMRALQHNKILTELRFHNQRHIMGSQVEMDIVKLLKDNTTLVKLGYHFELAGPRMSMTSILTRNMDKQRQKRMQEQKQQESGCNGAINPKTKALQKDTLGSSPYTSPKNSPWSSPKLPKKAQPAKSQPLAPPSPPPPPSPPPPPPPPLIVPEKKAPTRGIAEVIKQQESSRNTLQNGHKKKKGKKSKKHENSILKEIKNSLRSVSDKKSEEGSQPSTRPSTPQISLHDSLMEAIRGSNIKQLKRVEVPEALR

Target ORF information:

RefSeq Version	XM_006122591.2
Organism	Pelodiscus sinensis(Chinese soft-shelled turtle)
Definition	Pelodiscus sinensis leiomodin 2 (cardiac) (LMOD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006122591.2

ORF Insert Sequence:

ATGTCGACCT TTGGCTATAG AAGAGAGCTT AGTAAATATG AATCCATTGA TGAAGATGAA 
CTCCTCGCTT CTCTGACTGA TGAGGAGCTA AAGGAACTGG AAAGGGAACT AGAAGATATT 
GAGCCTGACC GTAACCTTCC AGTGGGGCAG CGACAAAAGA ATTTAACAGA GAAAACGCCA 
ACAGGAACTT TTAGCAGGGA AGCGTTGATG GCCTATTGGG AAAAAGAGAC CAGAAAACTC 
CTAGAAAAAG AAAGGTTGGG GGCGTGTGAA CAGGATTCAA AGCAAGACGA CAACAATTCA 
GAAGAGACCG AGGAAGAGTA TTTCACAGGA ACTAACAGTG AAATTTCTGA GGAGGTATAC 
ACTGAAGAGG AAGAGGAAGA GGAAGCAGAA GAAAAAGAAG AAGAAAAAGA GGAGGAGGAG 
GAAGAAGAAG AAGGAGACAG GGATGAAGGT GACTCAGAAA AAAAGGAAAA TGCTGCAGTT 
TGTGAAAGGA CTGTGACTTG TGAAAGTGGC AGGAGTTCTG ACCACTCCGA ACACAAGAAA 
TGCAACAGCC AAAAGGAAAA GGAAAAGGAA AATGTCATCA ATGGCAATGA CACAGAAGAT 
ATGAGCTTTA AAACAAGTGC CACCCACCTT TGTGGAAACC CAACGGTTAT TGAGGATACT 
TTGGAAAAAG TTCAGAACAA TGACCCTGAC ACCACTGAAG TCAACTTAAA TAACATTGAA 
AACATCACCA TACAGATGCT TACTCATTTC GCGCAAGCGC TCAAGAACAA CACAGTGGTT 
AAGATGTTCA ATCTGGCCAA TACTCGTGCT GATGATAATG CGGCAATTGC TATTGCTGGG 
ATGTTAAAAG TGAATCAGTA TATAACGAGT CTGAATGTAG ATTCAAATTT TATTACCGGC 
AAAGGGATAC TGTCCATCAT GAGAGCTTTG CAGCATAACA AGATTTTAAC AGAACTACGA 
TTCCACAACC AACGGCATAT CATGGGCAGT CAGGTTGAAA TGGACATTGT TAAACTGTTA 
AAAGACAATA CCACATTGGT GAAGCTAGGG TATCATTTTG AGCTTGCTGG ACCAAGAATG 
AGTATGACTA GTATTCTCAC AAGAAACATG GATAAACAAC GGCAAAAACG TATGCAGGAG 
CAAAAACAGC AAGAGTCTGG TTGTAATGGA GCAATCAATC CAAAGACCAA AGCCTTGCAG 
AAAGACACTC TTGGGTCCTC ACCTTACACA TCCCCTAAGA ACTCACCTTG GTCCTCTCCA 
AAACTTCCTA AAAAAGCTCA GCCTGCCAAA AGCCAGCCTC TGGCTCCTCC TTCACCCCCT 
CCTCCTCCTT CCCCACCTCC TCCTCCTCCT CCTCCTCTCA TTGTTCCAGA GAAGAAGGCA 
CCAACTAGGG GTATAGCTGA AGTCATCAAA CAACAAGAGA GCTCCAGGAA TACCTTACAA 
AATGGACACA AAAAGAAAAA AGGCAAAAAA AGCAAAAAGC ATGAAAATAG CATATTGAAA 
GAAATTAAAA ATTCCTTGAG ATCAGTCTCA GACAAGAAAT CAGAAGAAGG ATCACAACCC 
TCTACTCGGC CCTCCACCCC ACAAATATCT CTTCATGATA GCCTTATGGA AGCAATTCGC 
GGAAGCAATA TAAAACAGTT AAAGCGGGTG GAAGTGCCAG AAGCTCTTCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMOD2 ( XM_006122591.3 ) cDNA ORF clone, Pelodiscus sinensis(Chinese soft-shelled turtle) -> XP_006122653.1 Pelodiscus sinensis leiomodin 2 (LMOD2), mRNA.

Price & Availability↑

CloneID	OPe28908
Clone ID Related Accession (Same CDS sequence)	XM_006122591.2 , XM_006122591.3
Accession Version	XM_006122591.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-03
Organism	Pelodiscus sinensis(Chinese soft-shelled turtle)
Product	leiomodin-2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_005855045.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 4, 2018 this sequence version replaced XM_006122591.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pelodiscus sinensis Annotation Release 102 Annotation Version :: 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGACCT TTGGCTATAG AAGAGAGCTT AGTAAATATG AATCCATTGA TGAAGATGAA 
CTCCTCGCTT CTCTGACTGA TGAGGAGCTA AAGGAACTGG AAAGGGAACT AGAAGATATT 
GAGCCTGACC GTAACCTTCC AGTGGGGCAG CGACAAAAGA ATTTAACAGA GAAAACGCCA 
ACAGGAACTT TTAGCAGGGA AGCGTTGATG GCCTATTGGG AAAAAGAGAC CAGAAAACTC 
CTAGAAAAAG AAAGGTTGGG GGCGTGTGAA CAGGATTCAA AGCAAGACGA CAACAATTCA 
GAAGAGACCG AGGAAGAGTA TTTCACAGGA ACTAACAGTG AAATTTCTGA GGAGGTATAC 
ACTGAAGAGG AAGAGGAAGA GGAAGCAGAA GAAAAAGAAG AAGAAAAAGA GGAGGAGGAG 
GAAGAAGAAG AAGGAGACAG GGATGAAGGT GACTCAGAAA AAAAGGAAAA TGCTGCAGTT 
TGTGAAAGGA CTGTGACTTG TGAAAGTGGC AGGAGTTCTG ACCACTCCGA ACACAAGAAA 
TGCAACAGCC AAAAGGAAAA GGAAAAGGAA AATGTCATCA ATGGCAATGA CACAGAAGAT 
ATGAGCTTTA AAACAAGTGC CACCCACCTT TGTGGAAACC CAACGGTTAT TGAGGATACT 
TTGGAAAAAG TTCAGAACAA TGACCCTGAC ACCACTGAAG TCAACTTAAA TAACATTGAA 
AACATCACCA TACAGATGCT TACTCATTTC GCGCAAGCGC TCAAGAACAA CACAGTGGTT 
AAGATGTTCA ATCTGGCCAA TACTCGTGCT GATGATAATG CGGCAATTGC TATTGCTGGG 
ATGTTAAAAG TGAATCAGTA TATAACGAGT CTGAATGTAG ATTCAAATTT TATTACCGGC 
AAAGGGATAC TGTCCATCAT GAGAGCTTTG CAGCATAACA AGATTTTAAC AGAACTACGA 
TTCCACAACC AACGGCATAT CATGGGCAGT CAGGTTGAAA TGGACATTGT TAAACTGTTA 
AAAGACAATA CCACATTGGT GAAGCTAGGG TATCATTTTG AGCTTGCTGG ACCAAGAATG 
AGTATGACTA GTATTCTCAC AAGAAACATG GATAAACAAC GGCAAAAACG TATGCAGGAG 
CAAAAACAGC AAGAGTCTGG TTGTAATGGA GCAATCAATC CAAAGACCAA AGCCTTGCAG 
AAAGACACTC TTGGGTCCTC ACCTTACACA TCCCCTAAGA ACTCACCTTG GTCCTCTCCA 
AAACTTCCTA AAAAAGCTCA GCCTGCCAAA AGCCAGCCTC TGGCTCCTCC TTCACCCCCT 
CCTCCTCCTT CCCCACCTCC TCCTCCTCCT CCTCCTCTCA TTGTTCCAGA GAAGAAGGCA 
CCAACTAGGG GTATAGCTGA AGTCATCAAA CAACAAGAGA GCTCCAGGAA TACCTTACAA 
AATGGACACA AAAAGAAAAA AGGCAAAAAA AGCAAAAAGC ATGAAAATAG CATATTGAAA 
GAAATTAAAA ATTCCTTGAG ATCAGTCTCA GACAAGAAAT CAGAAGAAGG ATCACAACCC 
TCTACTCGGC CCTCCACCCC ACAAATATCT CTTCATGATA GCCTTATGGA AGCAATTCGC 
GGAAGCAATA TAAAACAGTT AAAGCGGGTG GAAGTGCCAG AAGCTCTTCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006122653.1
CDS	141..1814
Translation	MSTFGYRRELSKYESIDEDELLASLTDEELKELERELEDIEPDRNLPVGQRQKNLTEKTPTGTFSREALMAYWEKETRKLLEKERLGACEQDSKQDDNNSEETEEEYFTGTNSEISEEVYTEEEEEEEAEEKEEEKEEEEEEEEGDRDEGDSEKKENAAVCERTVTCESGRSSDHSEHKKCNSQKEKEKENVINGNDTEDMSFKTSATHLCGNPTVIEDTLEKVQNNDPDTTEVNLNNIENITIQMLTHFAQALKNNTVVKMFNLANTRADDNAAIAIAGMLKVNQYITSLNVDSNFITGKGILSIMRALQHNKILTELRFHNQRHIMGSQVEMDIVKLLKDNTTLVKLGYHFELAGPRMSMTSILTRNMDKQRQKRMQEQKQQESGCNGAINPKTKALQKDTLGSSPYTSPKNSPWSSPKLPKKAQPAKSQPLAPPSPPPPPSPPPPPPPPLIVPEKKAPTRGIAEVIKQQESSRNTLQNGHKKKKGKKSKKHENSILKEIKNSLRSVSDKKSEEGSQPSTRPSTPQISLHDSLMEAIRGSNIKQLKRVEVPEALR

Target ORF information:

RefSeq Version	XM_006122591.3
Organism	Pelodiscus sinensis(Chinese soft-shelled turtle)
Definition	Pelodiscus sinensis leiomodin 2 (LMOD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006122591.3

ORF Insert Sequence:

ATGTCGACCT TTGGCTATAG AAGAGAGCTT AGTAAATATG AATCCATTGA TGAAGATGAA 
CTCCTCGCTT CTCTGACTGA TGAGGAGCTA AAGGAACTGG AAAGGGAACT AGAAGATATT 
GAGCCTGACC GTAACCTTCC AGTGGGGCAG CGACAAAAGA ATTTAACAGA GAAAACGCCA 
ACAGGAACTT TTAGCAGGGA AGCGTTGATG GCCTATTGGG AAAAAGAGAC CAGAAAACTC 
CTAGAAAAAG AAAGGTTGGG GGCGTGTGAA CAGGATTCAA AGCAAGACGA CAACAATTCA 
GAAGAGACCG AGGAAGAGTA TTTCACAGGA ACTAACAGTG AAATTTCTGA GGAGGTATAC 
ACTGAAGAGG AAGAGGAAGA GGAAGCAGAA GAAAAAGAAG AAGAAAAAGA GGAGGAGGAG 
GAAGAAGAAG AAGGAGACAG GGATGAAGGT GACTCAGAAA AAAAGGAAAA TGCTGCAGTT 
TGTGAAAGGA CTGTGACTTG TGAAAGTGGC AGGAGTTCTG ACCACTCCGA ACACAAGAAA 
TGCAACAGCC AAAAGGAAAA GGAAAAGGAA AATGTCATCA ATGGCAATGA CACAGAAGAT 
ATGAGCTTTA AAACAAGTGC CACCCACCTT TGTGGAAACC CAACGGTTAT TGAGGATACT 
TTGGAAAAAG TTCAGAACAA TGACCCTGAC ACCACTGAAG TCAACTTAAA TAACATTGAA 
AACATCACCA TACAGATGCT TACTCATTTC GCGCAAGCGC TCAAGAACAA CACAGTGGTT 
AAGATGTTCA ATCTGGCCAA TACTCGTGCT GATGATAATG CGGCAATTGC TATTGCTGGG 
ATGTTAAAAG TGAATCAGTA TATAACGAGT CTGAATGTAG ATTCAAATTT TATTACCGGC 
AAAGGGATAC TGTCCATCAT GAGAGCTTTG CAGCATAACA AGATTTTAAC AGAACTACGA 
TTCCACAACC AACGGCATAT CATGGGCAGT CAGGTTGAAA TGGACATTGT TAAACTGTTA 
AAAGACAATA CCACATTGGT GAAGCTAGGG TATCATTTTG AGCTTGCTGG ACCAAGAATG 
AGTATGACTA GTATTCTCAC AAGAAACATG GATAAACAAC GGCAAAAACG TATGCAGGAG 
CAAAAACAGC AAGAGTCTGG TTGTAATGGA GCAATCAATC CAAAGACCAA AGCCTTGCAG 
AAAGACACTC TTGGGTCCTC ACCTTACACA TCCCCTAAGA ACTCACCTTG GTCCTCTCCA 
AAACTTCCTA AAAAAGCTCA GCCTGCCAAA AGCCAGCCTC TGGCTCCTCC TTCACCCCCT 
CCTCCTCCTT CCCCACCTCC TCCTCCTCCT CCTCCTCTCA TTGTTCCAGA GAAGAAGGCA 
CCAACTAGGG GTATAGCTGA AGTCATCAAA CAACAAGAGA GCTCCAGGAA TACCTTACAA 
AATGGACACA AAAAGAAAAA AGGCAAAAAA AGCAAAAAGC ATGAAAATAG CATATTGAAA 
GAAATTAAAA ATTCCTTGAG ATCAGTCTCA GACAAGAAAT CAGAAGAAGG ATCACAACCC 
TCTACTCGGC CCTCCACCCC ACAAATATCT CTTCATGATA GCCTTATGGA AGCAATTCGC 
GGAAGCAATA TAAAACAGTT AAAGCGGGTG GAAGTGCCAG AAGCTCTTCG ATGA