IL13 cDNA ORF clone, Ovis aries(sheep)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL13
Entrez Gene ID	664707
Full Name	interleukin 13
Gene Type	protein-coding
Organism	Ovis aries(sheep)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001082594.1	NP_001076063.1	interleukin-13 precursor
XM_012177595.2	XP_012032985.1	interleukin-13 isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Efficacy of IL-13 neutralization in a sheep model of experimental asthma.
Kasaian MT, Donaldson DD, Tchistiakova L, Marquette K, Tan XY, Ahmed A, Jacobson BA, Widom A, Cook TA, Xu X, Barry AB, Goldman SJ, Abraham WM
American journal of respiratory cell and molecular biology36(3)368-76(2007 Mar)

Sequence diversity and rates of molecular evolution between sheep and cattle genes.
Kijas JW, Menzies M, Ingham A
Animal genetics37(2)171-4(2006 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings suggest that IL-13 contributes to allergen-induced airway responses in this sheep model of asthma, and that neutralization of IL-13 is an effective strategy for blocking these A. suum-induced effects
Title: Efficacy of IL-13 neutralization in a sheep model of experimental asthma.

The following IL13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSm21023	NM_001082594.1 Latest version!	Ovis aries interleukin 13 (IL13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OSm22000	XM_012177595.2 Latest version!	Ovis aries interleukin 13 (IL13), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL13 ( NM_001082594.1 ) cDNA ORF clone, Ovis aries(sheep) -> NP_001076063.1 Ovis aries interleukin 13 (IL13), mRNA.

Price & Availability↑

CloneID	OSm21023
Clone ID Related Accession (Same CDS sequence)	NM_001082594.1
Accession Version	NM_001082594.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Ovis aries(sheep)
Product	interleukin-13 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ679798.1. ##Evidence-Data-START## Transcript exon combination :: DQ679798.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA104494983, SAMEA104495017 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCTCT TCTTGACCGT GGTCGTTGTT CTTACCTGCT TTGGTGGCCT CGCCTCCCCA 
AACCCTGTGC CTTCCTCTTC ATCCCTCAAG GAGCTCATTG AAGAGCTGGT TAATATCACC 
CAGAACCAGA AGGTGCCGCT GTGCAATGGC AGCATGGTGT GGAGCCTCAA CCTGACGAGC 
AGCATGTACT GTGCAGCCCT GGACTCCCTG ATCAGCATCT CCAACTGCAG TGTCATCCAC 
AGGACCAAGA GGATGCTGAG TGCGCTCTGT CCTCACAAGC CCTCAGCTAA GCATGTTTCC 
AGTGAGTACG TCCGAGACAC CAAAATTGAA GTGGCCCAGT TCTTAAAAGA CCTGCTCAGA 
CACTCAAGGA TCATTTTTCG CAATGGAAGT TACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001076063.1
CDS	55..453
Translation	MALFLTVVVVLTCFGGLASPNPVPSSSSLKELIEELVNITQNQKVPLCNGSMVWSLNLTSSMYCAALDSLISISNCSVIHRTKRMLSALCPHKPSAKHVSSEYVRDTKIEVAQFLKDLLRHSRIIFRNGSYN

Target ORF information:

RefSeq Version	NM_001082594.1
Organism	Ovis aries(sheep)
Definition	Ovis aries interleukin 13 (IL13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082594.1

ORF Insert Sequence:

ATGGCGCTCT TCTTGACCGT GGTCGTTGTT CTTACCTGCT TTGGTGGCCT CGCCTCCCCA 
AACCCTGTGC CTTCCTCTTC ATCCCTCAAG GAGCTCATTG AAGAGCTGGT TAATATCACC 
CAGAACCAGA AGGTGCCGCT GTGCAATGGC AGCATGGTGT GGAGCCTCAA CCTGACGAGC 
AGCATGTACT GTGCAGCCCT GGACTCCCTG ATCAGCATCT CCAACTGCAG TGTCATCCAC 
AGGACCAAGA GGATGCTGAG TGCGCTCTGT CCTCACAAGC CCTCAGCTAA GCATGTTTCC 
AGTGAGTACG TCCGAGACAC CAAAATTGAA GTGGCCCAGT TCTTAAAAGA CCTGCTCAGA 
CACTCAAGGA TCATTTTTCG CAATGGAAGT TACAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL13 ( XM_012177595.2 ) cDNA ORF clone, Ovis aries(sheep) -> XP_012032985.1 Ovis aries interleukin 13 (IL13), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OSm22000
Clone ID Related Accession (Same CDS sequence)	XM_012177595.2
Accession Version	XM_012177595.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	interleukin-13 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639014.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012177595.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCTCT TCTTGACCGT GGTCGTTGTT CTTACCTGCT TTGGTGGCCT CGCCTCCCCA 
AACCCTGTGC CTTCCTCTTC ATCCCTCAAG GAGCTCATTG AAGAGCTGGT TAATATCACC 
CAGAACCAGA AGGTGCCGCT GTGCAATGGC AGCATGGTGT GGAGCCTCAA CCTGACGAGC 
AGCATGTACT GTGCAGCCCT GGACTCCCTG ATCAGCATCT CCAACTGCAG TGTCATCCAC 
AGGACCAAGA GGATGCTGAG TGCGCTCTGT CCTCACAAGC CCTCAGCTAA GGTAAGGCCC 
CCCTGTCCTT TGACCTGGCA CCCACTTCTG CCAGCCCTGG GCTCACCCTG GGAGCCCCAG 
AGGAACCTGG CTGAGCATCT GAGGCATGTG TCCACAAAGG GGTGGGCCCA CTGTGGAAGC 
AGGGACATGG CTTTGGGATT TCCAAGACAT GGGCTTGAGG GCTCCCAACT CTTAGCTGAG 
CTTCATTCAG CCCCACATCT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_012032985.1
CDS	1330..1833
Translation	MALFLTVVVVLTCFGGLASPNPVPSSSSLKELIEELVNITQNQKVPLCNGSMVWSLNLTSSMYCAALDSLISISNCSVIHRTKRMLSALCPHKPSAKVRPPCPLTWHPLLPALGSPWEPQRNLAEHLRHVSTKGWAHCGSRDMALGFPRHGLEGSQLLAELHSAPHL

Target ORF information:

RefSeq Version	XM_012177595.2
Organism	Ovis aries(sheep)
Definition	Ovis aries interleukin 13 (IL13), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012177595.2

ORF Insert Sequence:

ATGGCGCTCT TCTTGACCGT GGTCGTTGTT CTTACCTGCT TTGGTGGCCT CGCCTCCCCA 
AACCCTGTGC CTTCCTCTTC ATCCCTCAAG GAGCTCATTG AAGAGCTGGT TAATATCACC 
CAGAACCAGA AGGTGCCGCT GTGCAATGGC AGCATGGTGT GGAGCCTCAA CCTGACGAGC 
AGCATGTACT GTGCAGCCCT GGACTCCCTG ATCAGCATCT CCAACTGCAG TGTCATCCAC 
AGGACCAAGA GGATGCTGAG TGCGCTCTGT CCTCACAAGC CCTCAGCTAA GGTAAGGCCC 
CCCTGTCCTT TGACCTGGCA CCCACTTCTG CCAGCCCTGG GCTCACCCTG GGAGCCCCAG 
AGGAACCTGG CTGAGCATCT GAGGCATGTG TCCACAAAGG GGTGGGCCCA CTGTGGAAGC 
AGGGACATGG CTTTGGGATT TCCAAGACAT GGGCTTGAGG GCTCCCAACT CTTAGCTGAG 
CTTCATTCAG CCCCACATCT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Efficacy of IL-13 neutralization in a sheep model of experimental asthma.
American journal of respiratory cell and molecular biology36(3)368-76(2007 Mar)
Kasaian MT,Donaldson DD,Tchistiakova L,Marquette K,Tan XY,Ahmed A,Jacobson BA,Widom A,Cook TA,Xu X,Barry AB,Goldman SJ,Abraham WM

Sequence diversity and rates of molecular evolution between sheep and cattle genes.
Animal genetics37(2)171-4(2006 Apr)
Kijas JW,Menzies M,Ingham A