TLR8 cDNA ORF clone, Ovis aries(sheep)

Gene
Clones
gRNAs

Summary

Gene Symbol	TLR8
Entrez Gene ID	554259
Full Name	toll like receptor 8
Gene Type	protein-coding
Organism	Ovis aries(sheep)

mRNA and Protein(s)

mRNA	Protein	Name
XM_012106137.2	XP_011961527.1	toll-like receptor 8 isoform X1
XM_012106133.2	XP_011961523.1	toll-like receptor 8 isoform X1
XM_012106133.3	XP_011961523.1	toll-like receptor 8 isoform X1
NM_001135929.1	NP_001129401.1	toll-like receptor 8 precursor
XM_012106138.2	XP_011961528.1	toll-like receptor 8 isoform X1
XM_012106135.2	XP_011961525.1	toll-like receptor 8 isoform X1
XM_012106134.2	XP_011961524.1	toll-like receptor 8 isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.
Ruscanu S, Pascale F, Bourge M, Hemati B, Elhmouzi-Younes J, Urien C, Bonneau M, Takamatsu H, Hope J, Mertens P, Meyer G, Stewart M, Roy P, Meurs EF, Dabo S, Zientara S, Breard E, Sailleau C, Chauveau E, Vitour D, Charley B, Schwartz-Cornil I
Journal of virology86(10)5817-28(2012 May)

Characterization of ovine TLR7 and TLR8 protein coding regions, detection of mutations and Maedi Visna virus infection.
Mikula I, Bhide M, Pastorekova S, Mikula I
Veterinary immunology and immunopathology138(1-2)51-9(2010 Nov)

Molecular cloning and characterization of Toll-like receptors 1-10 in sheep.
Chang JS, Russell GC, Jann O, Glass EJ, Werling D, Haig DM
Veterinary immunology and immunopathology127(1-2)94-105(2009 Jan)

Differential expression of pattern recognition receptors in sheep tissues and leukocyte subsets.
Nalubamba KS, Gossner AG, Dalziel RG, Hopkins J
Veterinary immunology and immunopathology118(3-4)252-62(2007 Aug)

Identification and expression of Toll-like receptors 1-10 in selected bovine and ovine tissues.
Menzies M, Ingham A
Veterinary immunology and immunopathology109(1-2)23-30(2006 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Bluetongue virus induces IFN-alpha/beta in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.
Title: The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.

Both mutations in TLR8, Asn165Lys (P-1.0) and Tyr349His (P-0.700), were present in extra LRR (leucine rich repeat) region. Mutations in TLR8 may play an important role as predisposition factor for Maedi Visna infection.
Title: Characterization of ovine TLR7 and TLR8 protein coding regions, detection of mutations and Maedi Visna virus infection.

The following TLR8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLR8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OSm21196	NM_001135929.1 Latest version!	Ovis aries toll like receptor 8 (TLR8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OSm21966	XM_012106137.2 Latest version!	Ovis aries toll-like receptor 8 (TLR8), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OSm21966	XM_012106133.3 Latest version!	Ovis aries toll like receptor 8 (TLR8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OSm21966	XM_012106135.2 Latest version!	Ovis aries toll-like receptor 8 (TLR8), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OSm21966	XM_012106134.2 Latest version!	Ovis aries toll-like receptor 8 (TLR8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
OSm21966	XM_012106138.2 Latest version!	Ovis aries toll-like receptor 8 (TLR8), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
View Old Accession Versions >>
OSm21966	XM_012106133.2	Ovis aries toll-like receptor 8 (TLR8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TLR8 ( NM_001135929.1 ) cDNA ORF clone, Ovis aries(sheep) -> NP_001129401.1 Ovis aries toll like receptor 8 (TLR8), mRNA.

Price & Availability↑

CloneID	OSm21196
Clone ID Related Accession (Same CDS sequence)	NM_001135929.1
Accession Version	NM_001135929.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3102bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-08-24
Organism	Ovis aries(sheep)
Product	toll-like receptor 8 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AM981306.1. ##Evidence-Data-START## Transcript exon combination :: AM981306.1 [ECO:0000332] ##Evidence-Data-END##

ATGACCCTTC ACTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAATACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129401.1
CDS	1..3102
Translation	MTLHFLLLTSLFLLISDSCEFFTEASYPRSYPCDVKNKNGSFIAECNSRRLQEVPQTVDKAVTEVDLSDNFITRITNESFQGLQNLTKINLNHNAKSQSGNPAVKKAMTITYGAFLNLKHLRELLLEDNQLQEIPAGLPESLKELSLIQNNIITLTKKNTSGLGNLERLYLGWNCYFACNKKFSIENGAFQNLTKLKVLSLSFNPLHSVPPSLPSSLTELYLSNTHIGNVSEEDFKELSNLRVLDLSGNCPRCFNAPFPCVPCQGGASIQIHPLAFQTLTQLRYLNLSSTSLRKVPASWFDNMHNLKVLDLEFNYLMDEIASGEFLTKLPSLEILDLSYNYELKKYPQYINISKNFSKLISLQMLHLRGYVFQELRRKDFKPLQHLSNLTTINLGVNFIKQIDFSIFHWFPNLKIVYLSENRISPLVSDTEQHDANGTFFQSHILKRRSADIQFDPHSNFYHNTHPLIKTECSRLGNALDLSLNSIFFIGVNQFKDFGNISCLNLSSNGNGQVLNGTEFSRLSGIKYLDLTNNRLDFDDDAAFSELPLLEVLDLSYNAHYFRIAGVTHRLGFIEHLTNLRVLNLSNNDIFTLTETQLKSASLGELVFSGNRLDLLWNAQDVRYWQIFQNLTNLTRLDLARNNLQHISSQAFLNLPRTLTDLYINDNMLNFFNWSLLEYFPHLRLLDLSGNQLFFLTNSLSTFASSLETLLLSRNRISHLPSDFLSGASSLIHLDLSSNQLKMLNRSTFETKTATKLTILELGSNPFDCTCDFGDFREWMDRNLNVRVPRLTDVICASPGDQEGKSIVSLDLTTCVSDTIAAIFCFLTFSVTISVMLAALAHHWFYWDAWFIYHVCLAKVKGYRSLSTSQTFYDAYVSYDTKDASVTDWVINELRFHLEESEDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMEENMDVIVFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTANDSRYNNLYVNSIKQY

Target ORF information:

RefSeq Version	NM_001135929.1
Organism	Ovis aries(sheep)
Definition	Ovis aries toll like receptor 8 (TLR8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135929.1

ORF Insert Sequence:

ATGACCCTTC ACTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAATACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_012106137.2 ) cDNA ORF clone, Ovis aries(sheep) -> XP_011961527.1 Ovis aries toll-like receptor 8 (TLR8), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OSm21966
Clone ID Related Accession (Same CDS sequence)	XM_012106137.2 , XM_012106133.2 , XM_012106133.3 , XM_012106138.2 , XM_012106135.2 , XM_012106134.2
Accession Version	XM_012106137.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3102bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	toll-like receptor 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639036.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012106137.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011961527.1
CDS	140..3241
Translation	MTLRFLLLTSLFLLISDSCEFFTEASYPRSYPCDVKNKNGSFIAECNSRRLQEVPQTVDKAVTEVDLSDNFITRITNESFQGLQNLTKINLNHNAKSQSGNPAVKKAMTITYGAFLNLKHLRELLLEDNQLQEIPAGLPESLKELSLIQNNIITLTKKNTSGLGNLERLYLGWNCYFACNKKFSIENGAFQNLTKLKVLSLSFNPLHSVPPSLPSSLTELYLSNTHIGNVSEEDFKELSNLRVLDLSGNCPRCFNAPFPCVPCQGGASIQIHPLAFQTLTQLRYLNLSSTSLRKVPASWFDNMHNLKVLDLEFNYLMDEIASGEFLTKLPSLEILDLSYNYELKKYPQYINISKNFSKLISLQMLHLRGYVFQELRRKDFKPLQHLSNLTTINLGVNFIKQIDFSIFHWFPNLKIVYLSENRISPLVSDTEQHDANGTFFQSHILKRRSADIQFDPHSNFYHNTHPLIKTECSRLGNALDLSLNSIFFIGVNQFKDFGNISCLNLSSNGNGQVLNGTEFSRLSGIKYLDLTNNRLDFDDDAAFSELPLLEVLDLSYNAHYFRIAGVTHRLGFIEHLTNLRVLNLSNNDIFTLTETQLKSASLGELVFSGNRLDLLWNAQDVRYWQIFQNLTNLTRLDLARNNLQHISSQAFLNLPRTLTDLYINDNMLNFFNWSLLEYFPHLRLLDLSGNQLFFLTNSLSTFASSLETLLLSRNRISHLPSDFLSGASSLIHLDLSSNQLKMLNRSTFETKTATKLTILELGSNPFDCTCDFGDFREWMDRNLNVRVPRLTDVICASPGDQEGKSIVSLDLTTCVSDTIAAIFCFLTFSVTISVMLAALAHHWFYWDAWFIYHVCLAKVKGYRSLSTSQTFYDAYVSYDTKDASVTDWVINELRFHLEESEDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMEENMDVIVFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTANDSRYNNLYVNSIKQY

Target ORF information:

RefSeq Version	XM_012106137.2
Organism	Ovis aries(sheep)
Definition	Ovis aries toll-like receptor 8 (TLR8), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012106137.2

ORF Insert Sequence:

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_012106133.2 ) cDNA ORF clone, Ovis aries(sheep) -> XP_011961523.1 Ovis aries toll-like receptor 8 (TLR8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OSm21966
Clone ID Related Accession (Same CDS sequence)	XM_012106137.2 , XM_012106133.2 , XM_012106133.3 , XM_012106138.2 , XM_012106135.2 , XM_012106134.2
Accession Version	XM_012106133.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3102bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	toll-like receptor 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639036.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012106133.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011961523.1
CDS	143..3244
Translation	MTLRFLLLTSLFLLISDSCEFFTEASYPRSYPCDVKNKNGSFIAECNSRRLQEVPQTVDKAVTEVDLSDNFITRITNESFQGLQNLTKINLNHNAKSQSGNPAVKKAMTITYGAFLNLKHLRELLLEDNQLQEIPAGLPESLKELSLIQNNIITLTKKNTSGLGNLERLYLGWNCYFACNKKFSIENGAFQNLTKLKVLSLSFNPLHSVPPSLPSSLTELYLSNTHIGNVSEEDFKELSNLRVLDLSGNCPRCFNAPFPCVPCQGGASIQIHPLAFQTLTQLRYLNLSSTSLRKVPASWFDNMHNLKVLDLEFNYLMDEIASGEFLTKLPSLEILDLSYNYELKKYPQYINISKNFSKLISLQMLHLRGYVFQELRRKDFKPLQHLSNLTTINLGVNFIKQIDFSIFHWFPNLKIVYLSENRISPLVSDTEQHDANGTFFQSHILKRRSADIQFDPHSNFYHNTHPLIKTECSRLGNALDLSLNSIFFIGVNQFKDFGNISCLNLSSNGNGQVLNGTEFSRLSGIKYLDLTNNRLDFDDDAAFSELPLLEVLDLSYNAHYFRIAGVTHRLGFIEHLTNLRVLNLSNNDIFTLTETQLKSASLGELVFSGNRLDLLWNAQDVRYWQIFQNLTNLTRLDLARNNLQHISSQAFLNLPRTLTDLYINDNMLNFFNWSLLEYFPHLRLLDLSGNQLFFLTNSLSTFASSLETLLLSRNRISHLPSDFLSGASSLIHLDLSSNQLKMLNRSTFETKTATKLTILELGSNPFDCTCDFGDFREWMDRNLNVRVPRLTDVICASPGDQEGKSIVSLDLTTCVSDTIAAIFCFLTFSVTISVMLAALAHHWFYWDAWFIYHVCLAKVKGYRSLSTSQTFYDAYVSYDTKDASVTDWVINELRFHLEESEDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMEENMDVIVFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTANDSRYNNLYVNSIKQY

Target ORF information:

RefSeq Version	XM_012106133.2
Organism	Ovis aries(sheep)
Definition	Ovis aries toll-like receptor 8 (TLR8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012106133.2

ORF Insert Sequence:

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_012106133.3 ) cDNA ORF clone, Ovis aries(sheep) -> XP_011961523.1 Ovis aries toll like receptor 8 (TLR8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OSm21966
Clone ID Related Accession (Same CDS sequence)	XM_012106137.2 , XM_012106133.2 , XM_012106133.3 , XM_012106138.2 , XM_012106135.2 , XM_012106134.2
Accession Version	XM_012106133.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3102bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-05
Organism	Ovis aries(sheep)
Product	toll-like receptor 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_040278.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 6, 2019 this sequence version replaced XM_012106133.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Ovis aries Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011961523.1
CDS	76..3177
Translation	MTLRFLLLTSLFLLISDSCEFFTEASYPRSYPCDVKNKNGSFIAECNSRRLQEVPQTVDKAVTEVDLSDNFITRITNESFQGLQNLTKINLNHNAKSQSGNPAVKKAMTITYGAFLNLKHLRELLLEDNQLQEIPAGLPESLKELSLIQNNIITLTKKNTSGLGNLERLYLGWNCYFACNKKFSIENGAFQNLTKLKVLSLSFNPLHSVPPSLPSSLTELYLSNTHIGNVSEEDFKELSNLRVLDLSGNCPRCFNAPFPCVPCQGGASIQIHPLAFQTLTQLRYLNLSSTSLRKVPASWFDNMHNLKVLDLEFNYLMDEIASGEFLTKLPSLEILDLSYNYELKKYPQYINISKNFSKLISLQMLHLRGYVFQELRRKDFKPLQHLSNLTTINLGVNFIKQIDFSIFHWFPNLKIVYLSENRISPLVSDTEQHDANGTFFQSHILKRRSADIQFDPHSNFYHNTHPLIKTECSRLGNALDLSLNSIFFIGVNQFKDFGNISCLNLSSNGNGQVLNGTEFSRLSGIKYLDLTNNRLDFDDDAAFSELPLLEVLDLSYNAHYFRIAGVTHRLGFIEHLTNLRVLNLSNNDIFTLTETQLKSASLGELVFSGNRLDLLWNAQDVRYWQIFQNLTNLTRLDLARNNLQHISSQAFLNLPRTLTDLYINDNMLNFFNWSLLEYFPHLRLLDLSGNQLFFLTNSLSTFASSLETLLLSRNRISHLPSDFLSGASSLIHLDLSSNQLKMLNRSTFETKTATKLTILELGSNPFDCTCDFGDFREWMDRNLNVRVPRLTDVICASPGDQEGKSIVSLDLTTCVSDTIAAIFCFLTFSVTISVMLAALAHHWFYWDAWFIYHVCLAKVKGYRSLSTSQTFYDAYVSYDTKDASVTDWVINELRFHLEESEDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMEENMDVIVFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTANDSRYNNLYVNSIKQY

Target ORF information:

RefSeq Version	XM_012106133.3
Organism	Ovis aries(sheep)
Definition	Ovis aries toll like receptor 8 (TLR8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012106133.3

ORF Insert Sequence:

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_012106138.2 ) cDNA ORF clone, Ovis aries(sheep) -> XP_011961528.1 Ovis aries toll-like receptor 8 (TLR8), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OSm21966
Clone ID Related Accession (Same CDS sequence)	XM_012106137.2 , XM_012106133.2 , XM_012106133.3 , XM_012106138.2 , XM_012106135.2 , XM_012106134.2
Accession Version	XM_012106138.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3102bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	toll-like receptor 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639036.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012106138.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011961528.1
CDS	172..3273
Translation	MTLRFLLLTSLFLLISDSCEFFTEASYPRSYPCDVKNKNGSFIAECNSRRLQEVPQTVDKAVTEVDLSDNFITRITNESFQGLQNLTKINLNHNAKSQSGNPAVKKAMTITYGAFLNLKHLRELLLEDNQLQEIPAGLPESLKELSLIQNNIITLTKKNTSGLGNLERLYLGWNCYFACNKKFSIENGAFQNLTKLKVLSLSFNPLHSVPPSLPSSLTELYLSNTHIGNVSEEDFKELSNLRVLDLSGNCPRCFNAPFPCVPCQGGASIQIHPLAFQTLTQLRYLNLSSTSLRKVPASWFDNMHNLKVLDLEFNYLMDEIASGEFLTKLPSLEILDLSYNYELKKYPQYINISKNFSKLISLQMLHLRGYVFQELRRKDFKPLQHLSNLTTINLGVNFIKQIDFSIFHWFPNLKIVYLSENRISPLVSDTEQHDANGTFFQSHILKRRSADIQFDPHSNFYHNTHPLIKTECSRLGNALDLSLNSIFFIGVNQFKDFGNISCLNLSSNGNGQVLNGTEFSRLSGIKYLDLTNNRLDFDDDAAFSELPLLEVLDLSYNAHYFRIAGVTHRLGFIEHLTNLRVLNLSNNDIFTLTETQLKSASLGELVFSGNRLDLLWNAQDVRYWQIFQNLTNLTRLDLARNNLQHISSQAFLNLPRTLTDLYINDNMLNFFNWSLLEYFPHLRLLDLSGNQLFFLTNSLSTFASSLETLLLSRNRISHLPSDFLSGASSLIHLDLSSNQLKMLNRSTFETKTATKLTILELGSNPFDCTCDFGDFREWMDRNLNVRVPRLTDVICASPGDQEGKSIVSLDLTTCVSDTIAAIFCFLTFSVTISVMLAALAHHWFYWDAWFIYHVCLAKVKGYRSLSTSQTFYDAYVSYDTKDASVTDWVINELRFHLEESEDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMEENMDVIVFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTANDSRYNNLYVNSIKQY

Target ORF information:

RefSeq Version	XM_012106138.2
Organism	Ovis aries(sheep)
Definition	Ovis aries toll-like receptor 8 (TLR8), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012106138.2

ORF Insert Sequence:

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_012106135.2 ) cDNA ORF clone, Ovis aries(sheep) -> XP_011961525.1 Ovis aries toll-like receptor 8 (TLR8), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OSm21966
Clone ID Related Accession (Same CDS sequence)	XM_012106137.2 , XM_012106133.2 , XM_012106133.3 , XM_012106138.2 , XM_012106135.2 , XM_012106134.2
Accession Version	XM_012106135.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3102bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	toll-like receptor 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639036.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012106135.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011961525.1
CDS	168..3269
Translation	MTLRFLLLTSLFLLISDSCEFFTEASYPRSYPCDVKNKNGSFIAECNSRRLQEVPQTVDKAVTEVDLSDNFITRITNESFQGLQNLTKINLNHNAKSQSGNPAVKKAMTITYGAFLNLKHLRELLLEDNQLQEIPAGLPESLKELSLIQNNIITLTKKNTSGLGNLERLYLGWNCYFACNKKFSIENGAFQNLTKLKVLSLSFNPLHSVPPSLPSSLTELYLSNTHIGNVSEEDFKELSNLRVLDLSGNCPRCFNAPFPCVPCQGGASIQIHPLAFQTLTQLRYLNLSSTSLRKVPASWFDNMHNLKVLDLEFNYLMDEIASGEFLTKLPSLEILDLSYNYELKKYPQYINISKNFSKLISLQMLHLRGYVFQELRRKDFKPLQHLSNLTTINLGVNFIKQIDFSIFHWFPNLKIVYLSENRISPLVSDTEQHDANGTFFQSHILKRRSADIQFDPHSNFYHNTHPLIKTECSRLGNALDLSLNSIFFIGVNQFKDFGNISCLNLSSNGNGQVLNGTEFSRLSGIKYLDLTNNRLDFDDDAAFSELPLLEVLDLSYNAHYFRIAGVTHRLGFIEHLTNLRVLNLSNNDIFTLTETQLKSASLGELVFSGNRLDLLWNAQDVRYWQIFQNLTNLTRLDLARNNLQHISSQAFLNLPRTLTDLYINDNMLNFFNWSLLEYFPHLRLLDLSGNQLFFLTNSLSTFASSLETLLLSRNRISHLPSDFLSGASSLIHLDLSSNQLKMLNRSTFETKTATKLTILELGSNPFDCTCDFGDFREWMDRNLNVRVPRLTDVICASPGDQEGKSIVSLDLTTCVSDTIAAIFCFLTFSVTISVMLAALAHHWFYWDAWFIYHVCLAKVKGYRSLSTSQTFYDAYVSYDTKDASVTDWVINELRFHLEESEDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMEENMDVIVFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTANDSRYNNLYVNSIKQY

Target ORF information:

RefSeq Version	XM_012106135.2
Organism	Ovis aries(sheep)
Definition	Ovis aries toll-like receptor 8 (TLR8), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012106135.2

ORF Insert Sequence:

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_012106134.2 ) cDNA ORF clone, Ovis aries(sheep) -> XP_011961524.1 Ovis aries toll-like receptor 8 (TLR8), transcript variant X2, mRNA.

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CloneID	OSm21966
Clone ID Related Accession (Same CDS sequence)	XM_012106137.2 , XM_012106133.2 , XM_012106133.3 , XM_012106138.2 , XM_012106135.2 , XM_012106134.2
Accession Version	XM_012106134.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3102bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-16
Organism	Ovis aries(sheep)
Product	toll-like receptor 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639036.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012106134.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011961524.1
CDS	148..3249
Translation	MTLRFLLLTSLFLLISDSCEFFTEASYPRSYPCDVKNKNGSFIAECNSRRLQEVPQTVDKAVTEVDLSDNFITRITNESFQGLQNLTKINLNHNAKSQSGNPAVKKAMTITYGAFLNLKHLRELLLEDNQLQEIPAGLPESLKELSLIQNNIITLTKKNTSGLGNLERLYLGWNCYFACNKKFSIENGAFQNLTKLKVLSLSFNPLHSVPPSLPSSLTELYLSNTHIGNVSEEDFKELSNLRVLDLSGNCPRCFNAPFPCVPCQGGASIQIHPLAFQTLTQLRYLNLSSTSLRKVPASWFDNMHNLKVLDLEFNYLMDEIASGEFLTKLPSLEILDLSYNYELKKYPQYINISKNFSKLISLQMLHLRGYVFQELRRKDFKPLQHLSNLTTINLGVNFIKQIDFSIFHWFPNLKIVYLSENRISPLVSDTEQHDANGTFFQSHILKRRSADIQFDPHSNFYHNTHPLIKTECSRLGNALDLSLNSIFFIGVNQFKDFGNISCLNLSSNGNGQVLNGTEFSRLSGIKYLDLTNNRLDFDDDAAFSELPLLEVLDLSYNAHYFRIAGVTHRLGFIEHLTNLRVLNLSNNDIFTLTETQLKSASLGELVFSGNRLDLLWNAQDVRYWQIFQNLTNLTRLDLARNNLQHISSQAFLNLPRTLTDLYINDNMLNFFNWSLLEYFPHLRLLDLSGNQLFFLTNSLSTFASSLETLLLSRNRISHLPSDFLSGASSLIHLDLSSNQLKMLNRSTFETKTATKLTILELGSNPFDCTCDFGDFREWMDRNLNVRVPRLTDVICASPGDQEGKSIVSLDLTTCVSDTIAAIFCFLTFSVTISVMLAALAHHWFYWDAWFIYHVCLAKVKGYRSLSTSQTFYDAYVSYDTKDASVTDWVINELRFHLEESEDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTIFVLTKKYAKNWNFKTAFYLALQRLMEENMDVIVFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQSLKNVVLTANDSRYNNLYVNSIKQY

Target ORF information:

RefSeq Version	XM_012106134.2
Organism	Ovis aries(sheep)
Definition	Ovis aries toll-like receptor 8 (TLR8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012106134.2

ORF Insert Sequence:

ATGACCCTTC GCTTTTTGCT TCTGACCTCC CTTTTCCTGC TCATCTCCGA TTCCTGTGAG 
TTCTTCACTG AAGCCAGTTA TCCCCGAAGC TATCCTTGCG ATGTGAAAAA CAAAAATGGC 
TCTTTTATTG CAGAATGTAA CAGTCGTCGA TTACAGGAAG TACCCCAAAC AGTGGACAAA 
GCTGTGACAG AAGTAGACCT GTCTGATAAT TTCATCACAC GTATAACGAA TGAATCCTTT 
CAAGGGCTGC AAAATCTGAC TAAAATCAAC CTGAACCATA ATGCCAAGTC CCAGAGTGGA 
AATCCTGCTG TAAAGAAAGC TATGACTATT ACATACGGGG CATTTCTCAA CCTCAAACAC 
CTAAGGGAGT TGCTGCTGGA AGACAACCAG TTACAAGAAA TACCGGCTGG TTTGCCAGAA 
TCTTTGAAAG AACTTAGTCT AATTCAAAAC AACATAATTA CGTTAACGAA AAAGAACACT 
TCTGGACTTG GGAACCTGGA ACGTCTCTAT TTGGGCTGGA ACTGTTATTT TGCTTGTAAT 
AAAAAATTTA GCATAGAAAA TGGAGCATTC CAAAACCTTA CCAAGTTGAA GGTGCTGTCA 
TTATCTTTTA ATCCCCTTCA CAGCGTGCCA CCGAGTCTGC CAAGCTCGCT AACAGAACTC 
TACCTTAGCA ATACCCATAT TGGAAACGTC AGTGAAGAAG ACTTCAAGGA ACTGAGCAAT 
TTAAGAGTAC TAGATTTAAG CGGAAACTGC CCGAGATGTT TTAACGCTCC GTTTCCCTGT 
GTACCTTGCC AAGGAGGTGC TTCAATTCAG ATACACCCTC TTGCTTTTCA AACCCTGACC 
CAACTTCGCT ACCTAAACCT CTCTAGCACT TCGCTCCGGA AGGTTCCTGC CAGCTGGTTT 
GACAACATGC ACAATCTGAA GGTGTTGGAT CTTGAATTCA ACTATTTAAT GGACGAAATA 
GCCTCGGGGG AATTTTTGAC AAAATTGCCC TCCTTAGAAA TACTTGATTT ATCTTACAAC 
TACGAACTGA AAAAATATCC TCAGTACATT AACATTTCCA AAAATTTCTC GAAGCTTATA 
TCTCTCCAGA TGTTGCATTT AAGAGGTTAT GTGTTCCAGG AACTTAGAAG GAAAGATTTC 
AAGCCCCTGC AGCACCTCTC AAATTTAACG ACTATCAACT TGGGCGTTAA CTTTATTAAG 
CAGATTGATT TTAGCATTTT CCACTGGTTC CCCAACCTGA AAATCGTTTA CTTGTCAGAA 
AACAGAATAT CGCCCTTGGT CAGTGATACT GAGCAACATG ATGCAAATGG GACCTTTTTC 
CAGAGTCACA TCCTGAAGCG ACGCTCAGCT GATATTCAAT TTGACCCACA TTCGAATTTT 
TATCATAACA CCCATCCTTT AATAAAGACA GAATGTTCAC GTCTTGGCAA TGCCTTAGAT 
TTAAGCTTGA ACAGTATTTT CTTTATTGGG GTAAACCAGT TTAAAGATTT TGGAAACATT 
TCCTGTTTAA ATCTGTCTTC AAATGGCAAT GGCCAGGTGT TAAATGGAAC GGAATTTTCA 
CGCTTGTCTG GTATCAAGTA TTTGGATTTG ACAAACAATA GACTAGACTT TGATGATGAT 
GCTGCTTTCA GTGAGTTGCC GTTGTTGGAA GTTCTCGATC TCAGCTACAA TGCGCACTAT 
TTCCGAATAG CAGGGGTAAC GCACCGTCTA GGGTTTATTG AACATTTAAC TAACCTGAGA 
GTTTTAAACT TGAGCAACAA TGACATTTTT ACTTTAACAG AAACACAACT GAAAAGTGCG 
TCCCTAGGAG AATTAGTTTT CAGTGGGAAC CGCCTTGACC TTCTGTGGAA TGCTCAAGAT 
GTCAGGTACT GGCAAATTTT TCAAAATCTC ACCAATCTGA CCCGGCTTGA CTTAGCCCGT 
AATAACCTTC AGCATATCTC CAGTCAGGCC TTCCTTAACT TGCCCAGGAC TCTCACTGAC 
CTATATATAA ATGATAACAT GTTAAATTTC TTTAACTGGT CATTACTGGA ATACTTCCCT 
CACCTCAGGT TGCTTGACTT AAGTGGAAAC CAGCTGTTCT TTTTAACCAA TAGCCTATCT 
ACATTTGCAT CTTCTCTTGA GACACTACTA CTGAGTCGAA ACAGAATTTC CCACCTGCCA 
TCTGACTTTC TTTCTGGAGC CAGCAGCCTG ATACACCTCG ATTTGAGCTC CAACCAGCTC 
AAGATGCTCA ACAGATCCAC GTTTGAAACG AAGACCGCCA CCAAGTTAAC CATTTTGGAA 
CTAGGGAGTA ACCCTTTTGA CTGTACCTGT GACTTCGGAG ATTTTCGAGA ATGGATGGAC 
AGAAATCTGA ATGTCAGGGT TCCCAGACTG ACTGATGTCA TTTGTGCCAG TCCTGGGGAT 
CAAGAAGGCA AGAGCATTGT GAGTCTAGAC CTCACCACTT GTGTTTCAGA TACCATTGCG 
GCCATATTCT GTTTCTTAAC CTTTTCTGTC ACCATCTCAG TGATGCTGGC TGCCCTGGCC 
CACCACTGGT TTTACTGGGA TGCTTGGTTT ATCTACCATG TGTGCTTAGC TAAGGTCAAA 
GGCTACAGGT CTCTGTCCAC ATCCCAGACT TTCTACGATG CTTACGTTTC TTATGACACC 
AAAGACGCTT CTGTCACGGA CTGGGTGATC AATGAATTGC GCTTCCACCT GGAAGAGAGT 
GAGGACAAGA ACGTGCTCCT GTGTTTAGAG GAAAGGGATT GGGACCCGGG TCTAGCCATC 
ATCGACAACC TCATGCAGAG CATCAACCAA AGCAAGAAAA CAATATTTGT TTTAACCAAA 
AAATATGCCA AAAACTGGAA TTTTAAAACG GCATTCTACT TGGCCTTGCA GAGGCTAATG 
GAGGAGAATA TGGATGTGAT TGTCTTTATT CTGCTGGAGC CAGTGTTGCA GCATTCGCAG 
TATTTGAGGC TGCGGCAGAG GATCTGCAAG AGTTCCATCC TCCAGTGGCC TGATAACCCC 
AAGGCAGAAG GCTTGTTTTG GCAGAGTCTG AAAAATGTCG TCCTAACAGC CAACGATTCA 
CGGTATAACA ACTTGTATGT CAATTCCATT AAGCAGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.
Journal of virology86(10)5817-28(2012 May)
Ruscanu S,Pascale F,Bourge M,Hemati B,Elhmouzi-Younes J,Urien C,Bonneau M,Takamatsu H,Hope J,Mertens P,Meyer G,Stewart M,Roy P,Meurs EF,Dabo S,Zientara S,Breard E,Sailleau C,Chauveau E,Vitour D,Charley B,Schwartz-Cornil I

Characterization of ovine TLR7 and TLR8 protein coding regions, detection of mutations and Maedi Visna virus infection.
Veterinary immunology and immunopathology138(1-2)51-9(2010 Nov)
Mikula I,Bhide M,Pastorekova S,Mikula I

Molecular cloning and characterization of Toll-like receptors 1-10 in sheep.
Veterinary immunology and immunopathology127(1-2)94-105(2009 Jan)
Chang JS,Russell GC,Jann O,Glass EJ,Werling D,Haig DM

Differential expression of pattern recognition receptors in sheep tissues and leukocyte subsets.
Veterinary immunology and immunopathology118(3-4)252-62(2007 Aug)
Nalubamba KS,Gossner AG,Dalziel RG,Hopkins J

Identification and expression of Toll-like receptors 1-10 in selected bovine and ovine tissues.
Veterinary immunology and immunopathology109(1-2)23-30(2006 Jan)
Menzies M,Ingham A

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TLR8 cDNA ORF clone, Ovis aries(sheep)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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