| Gene Symbol | IL6 |
| Entrez Gene ID | 100008733 |
| Full Name | interleukin 6 |
| Synonyms | IL-6 |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
ORF » Species Summary » Oryctolagus cuniculus » IL6 cDNA ORF clone
| Gene Symbol | IL6 |
| Entrez Gene ID | 100008733 |
| Full Name | interleukin 6 |
| Synonyms | IL-6 |
| Gene Type | protein-coding |
| Organism | Oryctolagus cuniculus(rabbit) |
| mRNA | Protein | Name |
|---|---|---|
| NM_001082064.2 | NP_001075533.1 | interleukin-6 precursor |
Convergent evolution of IL-6 in two leporids (Oryctolagus and Pentalagus) originated an extended protein.
Neves F, Abrantes J, Pinheiro A, Almeida T, Costa PP, Esteves PJ
Immunogenetics66(9-10)589-95(2014 Oct)
Heat effect induces production of inflammatory cytokines through heat shock protein 90 pathway in cornea cells.
Tsai MJ, Hsu YL, Wu KY, Yang RC, Chen YJ, Yu HS, Kuo PL
Current eye research38(4)464-71(2013 Apr)
The complete cDNA sequences of IL-2, IL-4, IL-6 AND IL-10 from the European rabbit (Oryctolagus cuniculus).
Perkins HD, van Leeuwen BH, Hardy CM, Kerr PJ
Cytokine12(6)555-65(2000 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 in rabbit cornea cells.
Title: Heat effect induces production of inflammatory cytokines through heat shock protein 90 pathway in cornea cells.
The following IL6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OOb30137 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001082064.2 | |
| Accession Version | NM_001082064.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Oryctolagus cuniculus(rabbit) | |
| Product | interleukin-6 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF169176.1. On Aug 31, 2012 this sequence version replaced NM_001082064.1. ##Evidence-Data-START## Transcript exon combination :: AF169176.1, DQ680161.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00013641, SAMN03328718 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAACTCCT TCACAAGCGC CCTCCGCCCA GGTCCCCTCG GCTGCTCGCT GGCGCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001075533.1 |
| CDS | 52..777 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001082064.2 |
1 | ATGAACTCCT TCACAAGCGC CCTCCGCCCA GGTCCCCTCG GCTGCTCGCT GGCGCTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Convergent evolution of IL-6 in two leporids (Oryctolagus and Pentalagus) originated an extended protein. |
Heat effect induces production of inflammatory cytokines through heat shock protein 90 pathway in cornea cells. |
The complete cDNA sequences of IL-2, IL-4, IL-6 AND IL-10 from the European rabbit (Oryctolagus cuniculus). |