POLE cDNA ORF clone, Ochotona princeps(American pika)

Gene
Clones
gRNAs

Summary

Gene Symbol	POLE
Entrez Gene ID	101523960
Full Name	DNA polymerase epsilon, catalytic subunit
Gene Type	protein-coding
Organism	Ochotona princeps(American pika)

mRNA and Protein(s)

mRNA	Protein	Name
XM_012929854.1	XP_012785308.1	DNA polymerase epsilon catalytic subunit A

Pathways from BioSystems
Gene Ontology

The following POLE gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POLE cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OOc84630	XM_012929854.1 Latest version!	Ochotona princeps polymerase (DNA directed), epsilon, catalytic subunit (POLE), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	29-31	$1161.30 $1659.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

POLE ( XM_012929854.1 ) cDNA ORF clone, Ochotona princeps(American pika) -> XP_012785308.1 Ochotona princeps polymerase (DNA directed), epsilon, catalytic subunit (POLE), mRNA.

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CloneID	OOc84630
Clone ID Related Accession (Same CDS sequence)	XM_012929854.1
Accession Version	XM_012929854.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6435bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-06-18
Organism	Ochotona princeps(American pika)
Product	DNA polymerase epsilon catalytic subunit A
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_004535511.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ochotona princeps Annotation Release 101 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.3 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END##

ATGGACTTGC GGTTTGGATT TGAGAGGTTG AAAGAGCCTG GTGAGAAGAC GGGCTGGCTC 
ATCAACATGC ACCCTACTGA AATCTTAGAT GAAGATAAAC GCTTAATCAG TGCGGTGGAT 
TACTACTTTA TTCAAGATGA TGGGAGCAGA TTTAAGCAAA GTGTGTTGCA GGGGGGTGGT 
GTGATTACTG ATGAAGAGGA AGCCTCTAAG AAGATAGCCA ACCAACTGGA CAACATAGTG 
GACATGCGGG AGTATGACGT CCCCTATCAT ATCCGCCTCT CCATTGACCT CAAAATACAC 
GTGGCCCATT GGTATAACGT CAGATTCCGA GGAAACGCTT TTCCAGTGGA AATTGCCCGC 
CGAGATGACC TTGTTGAACG ACCTGACCCT GTGGTTCTGG CATTTGACAT CGAGACGACC 
AAACTACCCC TCAAATTTCC TGATGCTGAG ACGGACCAGA TCATGATGAT TTCTTACATG 
ATTGATGGCC AGGGCTACCT CATCACCAAC AGGGAGATTG TTTCAGAAGA CATTGAAGAC 
TTCGAGTTTA CCCCCAAGCA AGAATACGAG GGGCCCTTTT GTGTCTTCAA TGAACCTGAT 
GAGGTTCATC TGATCCAGAG GTGGTTTGAA CATATCCAGG AAACCAAACC CAGCATCATG 
GTCACCTACA ATGGAGACTT CTTTGATTGG CCATTTGTGG AGGCCAGGGC AGCAGTCCAT 
GGCCTGAGCA TGTATCAGGA GATCGGCTTC CAGAAGGACA ACCAGGGGGA GTACAAGGCG 
CCCCAGTGCA TCCACATGGA TTGTCTCAGG TGGGTGAAGA GAGACAGCTA TCTTCCTGTG 
GGCAGTCATA ATCTTAAGGC AGCTGCTAAG GCCAAGCTGG GCTATGACCC TGTAGAGCTG 
GACCCTGAGG ACATGTGCCG AATGGCCACT GAGCAACCCC AGACTCTGGC TACATATTCA 
GTGTCAGATG CTGTTGCTAC TTACTACCTG TACATGAAGT ATGTCCACCC TTTCATATTT 
GCCCTCTGCA CCATTATTCC CATGGAGCCC GATGAGGTGC TGCGGAAGGG CTCTGGCACG 
CTGTGCGAGG CCTTGCTGAT GGTGCAGGCC TACCATGCCA ACATCATCTT CCCCAACAAG 
CAGGAGCAAG AGTTCAACAA GCTGACAGAT GATGGCCATG TCCTGGACGC TGAGACCTAC 
GTTGGGGGGC ATGTGGAGGC GCTGGAATCT GGGGTCTTCC GAAGTGACAT CCCCTGCCGG 
TTTAGGATGA ATCCTGCCGC CTTTGACTCC CTGCTGCAGC GAGTTGAGAA GACCTTGCGT 
CATGCCATTG AAGAAGAGGA GAAGGTGCCA ATGGAGCAAG TCACCAACTT CCAGGAGGTG 
TGTGATCAGA TTAAGACCAA GCTTAGCTCC CTGAAAGATG TCCCTAACCG AATCGAGTGT 
CCCCTTATCT ACCACCTGGA TGTGGGAGCA ATGTACCCCA ACATTATCCT GACAAACCGC 
CTACAGCCCT CAGCCATGGT GGATGAGGCC ACCTGTGCTG CATGTGACTT CAACAAGCCT 
GGAGCCAACT GCCAGAGGAA GATGGCTTGG CAGTGGAGGG GCGAGTTTAT GCCTGCCAGT 
CGCAGTGAAT ATCATCGGAT TCAGCACCAG TTGGAGTCAG AAAAGTTTCC CCCCTTGTTC 
CCAGAGGGAC CCGCTCGAGC CTTTCACGAA CTGTCACGTG AGGAACAAGC TAAATATGAG 
AAGAGGAGGC TGGCAGATTA CTGCCGGAAA GCCTACAAAA AGATCCACAT CACTAAGGTG 
GAGGAGCGCC TCACCACCAT CTGCCAACGG GAGAACTCCT TCTACGTGGA CACAGTGCGA 
GCCTTTCGGG ACAGGCGCTA CGAGTTCAAA GGGCTTCACA AGGTGTGGAA AAAGAAGCTT 
TCAGCAGCTG TGGAGGTGGG TGACGCAGCT GAGGTGAAGC GCTGCAAGAA CATGGAGGTG 
CTGTATGACT CCCTGCAGCT GGCCCACAAG TGCATCCTCA ACTCCTTCTA CGGCTATGTT 
ATGCGCAAAG GAGCTCGCTG GTACTCCATG GAGATGGCTG GCATCGTCTG TTTCACAGGG 
GCCAACCTCA TCACTCAGGC CCGGGAGCTC ATTGAGCAGA TCGGGAGGCC CTTGGAACTG 
GACACAGATG GAATATGGTG TGTCCTGCCG AATAGCTTCC CAGAAAATTT TGTCATCAAG 
ACGACTAATG CGAAGAAGCC CAAGGTGACC ATTTCCTACC CTGGAGCCAT GTTGAACATC 
ATGGTCAAGG AAGGTTTCAC CAATCACCAG TACCAGGAGC TGGCAGAACC TTCCTCCCTC 
ACCTATGTCA CCCGCTCAGA GAACAGCATC TTTTTTGAGG TTGATGGGCC CTACCTCGCC 
ATGATCCTTC CAGCCTCCAA GGAAGAAGGC AAGAAACTGA AGAAGAGGTA TGCTGTGTTC 
AATGAAGATG GATCTCTGGC TGAGCTAAAG GGCTTTGAGG TGAAACGCCG TGGGGAGCTG 
CAGCTGATTA AAATCTTCCA GTCCTCGGTA TTTGAGGCCT TCCTCAAGGG TAGCACGCTG 
GAGGAGGTAT ACGGTTCTGT TGCCAAGGTG GCCGACTACT GGCTGGATGT GCTGTACAGT 
AAGGCTGCCA ACATGCCAGA TTCTGAGCTG TTCGAGCTCA TCTCCGAGAA CCGGTCCATG 
TCACGGAAGC TGGAAGACTA CGGGGAGCAG AAGTCCACGT CCATCAGCAC TGCCAAGCGC 
CTGGCCGAGT TCCTGGGAGA CCAGATGGTC AAGGACGCGG GCCTCAGCTG CCGCTATATC 
ATCTCCCGAA AGCCCGAGGG CTCTCCTGTC ACTGAGAGGG CCATCCCACT TGCCATTTTC 
CAAGCAGAGC CTACAGTAAG GAAGCACTTT CTCCGGAAAT GGCTTAAGAG CTCGTCTCTT 
CAGGACTTTG ATATTCGGAC AATCCTTGAC TGGGACTACT ACATCGAACG GCTGGGCAGT 
GCCATCCAGA AGATCATCAC CATCCCCGCC GCTCTGCAGC AGGTGAAGAA TCCTGTGCCA 
CGTGTGAAAC ACCCTGACTG GCTGCACAAA AAGCTGCTGG AGAAGACTGA TGTCTACAAG 
CAGAAGAAGA TCAGCGAGCT CTTCACTCTG GAGGGCAGGA GACAGGTTAT GTTGGCACAG 
GTCCCTGACA GCAGTCCAAG GCCAGACACT CCTGACATGG AGGACTTTGG CCTCCAAAAA 
TTGCCCTCCT CAGTGGTCCC TGTTGCAACC AAGAGGAAGC GAATCCTGTG GGAAAGCCAG 
GAGGAGTCTC AGGACCCAGC ATTGATTGTG CCCTGGCAGG AGATCTTGGG GCAGCCCCCT 
GCCCTTGGAA CCACCCAGGA GGAGTGGCTG GTCTGGCTCG GCTTCCACAA GAAGAAGTGG 
CAACTGCAGG CCCGGCAGCG CATGGCTCGC AGAAAGAAGC GGCGTTTAGA GCCAGAGCAG 
GGTACTTCGA GGCCTGTGGC CGTTCGAGAC GGGCCTGCCA CGGGGCTGGG GAGCTTCTTG 
CGAAGAACTG CCCGCAGTGT GCTGGACCTT CCGTGGCAGA TTGTGCAGAT CAGTGAGACC 
AGCCAGGCTG GCTTCTTCAG GCTGTGGGCC ATCATTGGCA GTGACTTGCA CTGCATCAAG 
CTGAATATTT CCCGTGTGTT CTATGTGAAC CAGCGAGTGG CCAAAGCAGA GGAGGGGCCT 
TCGTATCGAA AGGTGAATCG ATTCCTTCCT CGTTCCAACA TGGTCTACAA TCTCTATGAG 
TACTCAGTGC CAGAGGAGCT GTACCAAGAA CACATCAACG AAATCAATAC CGAGCTGTCA 
GCACCAGATA TTGAGGGTGT CTACGAGACT CAGGTTCCTT TGTTGTTCCG AGCCATTGTG 
CAGCTGGGCT GTGTGTGTGT CGTCAACAAG CAGCTGGCAA GGCACCTGTC AGGCTGGGAA 
ACCGAAACCT TTGCTCTGGA GCACCTGGAA ATGCGTTCTC TAGCTCAATT CAGCTACCTG 
GAGCCAGGGA GCATCCGCCA CATCTACCTC TACCACCACT CACAGGGCCA CAAAGCACTC 
TTTGGGATCT TCATCCCCTC ACAGCGCAGA GCGTCTGTAT TTGTGCTGGA CACGGTGCGC 
AGCAACCAAA TGCCCAATCT CAGTGCGCTC TACTCAGCGG AGCACAGCCT CCTGCTGGAG 
AAGGTGGGCC CCGATCTCCT GCCACCCCCA AAACACACCT TTGAAGTGCG CGCAGAGACA 
GACCTGAAGA CCATCTGCAG AGCCATACAG CGTTTTCTGC TCGCCTACAA GGAAGAGCGT 
CGAGGGCCTA CCCTAGTGGC CATCCAGTCC AGCTGGGAAC TGAAGCGGCT AGTAGGTGAG 
ATTCCTATCT TGGAGGAATT CCCACTGGTA CCTGTGCATG TGGCTGACAA GATCAGCTAT 
GGAGTCCTGG ACTGGCAGCG GCATGGAGCC CGACGAATGA TCCGACACTA CCTCAACCTC 
GACACGTGCT TGTCCCAGGC CTTTGAGATG AGCAGGTACT TTCACATTCC CATTGGGAAT 
CTGCCAGAGG ACATCTCCAC CTTTGGCTCT GACCTCTTCT TCGCACGCCA CCTCCAGCGC 
CACAACCACC TGCTCTGGTT GTCTCCTACA GCCCGCCCTG ACTTAGGCGG GAAGGAGGCT 
GACGACAGCC GCCTCGTCAT GGAGTTCGAT GATCAAGCCA CAGTGGAGAT CAACAATTCA 
GGCTGCTACT CCACGGTGTG TGTAGAGCTG GACATGCAGA ACCTGGCCGT CAACACCATC 
CTTCAGTCTC ACCACGTCAA CGACATGGAG GGGACTGACA GTGTGAGCGT CAGCTTCGAT 
GCAGTCGCCC AGGCCTCCCT TGAGGAAATG GTCACAGGCA TTCAAGCCAC CAGCACCCCA 
GCCAGCTATG ATGAGACTGC TCTCCGCCCC AGCACATTCA GGATTCTGAA GAGCATGGTG 
GTGGGCTGGG TCAAGGAGAT CACGCAGTAC CACAATGTGT ACGCGGACAA CCAGGTAATG 
CACTTTTACC GCTGGATCCG GTCACCGTCA TCCCTGCTCC ATGACCCTGC TCTTCACCGG 
ACTCTGCACA ACATGATGAA GAAGCTTTTC CTGCAGCTCA TCTCTGAGTT CAAGCGCCTG 
GGGTCTTCAG TTGTCTATGC CAACTTCAAC CGCATCATCC TCTGTACAAA AAAGCGCCGG 
ATTGAAGATG CTATTGCCTA CATAGAGTAC ATCACCAACA GTATCCACTC CAAAGAAATC 
TTCCATTCCC TGACAATTTC CTTCTCACGG TGCTGGGAAT TTCTTCTCTG GATGGATCCG 
TCCAACTATG GTGGAATCAA GGGCAAAGTG TCCTCCCGTG TTCACTGTGG ACAGGTGAGA 
GCTAGTGATC CTCAGGAAGG AGAGGCAGTG GAGGATGACG AGGAGGAAGA TTCAGAGGAG 
GACGATGTGG AGGAGTCCCA GTCCGATGTG GAGGACTTAC TAGAAAACAA CTGGAATATC 
CTGCAGTTCT TGCCCCAGGC AGCCTCCTGC CAAAGCTACT TCCTCATGAT TGTTTCAGCA 
TACATTGTGG CTGTGTACCA CAGCATGAAG GACGAGCTGA GGCGCACTGC CCCAGGGAGC 
ACCCCTGTGA AGAAGAGAAA CTCCAGCCAG CTCTCCCAGG AAGCTGAAGG GGCAGCTGGA 
GCCCTTCCTG GAATGATCAC CTTCTCTCAG GATTATGTGG CAAATGAGCT GACTCAGAGC 
TTTTTCACCA TAACCCAGAA AATCCAGAAG AAAGTCACAG GATCTCGGAA CTCGACAGAG 
CCTTCAGACA TGTTCCCTGT GCTCCCTGGT TCTCATTTGG TGCTCAGCAA TCCTGCTCTG 
GAGTTCATCA AATGCGTATG CAAGGTCCTG TCCCTGGACA CCAACATCAC TAACCAGGTG 
AATAAGCTGA ACCGAGACCT ACTGCGCCTG GTAGGTGTCG GCGAGTTCTC CGAGGAGGCC 
CAGTTCAGAG ACCCCTGCCG CTCCTATGTG CTCGCGGAGG TCATCTGCCG CAGCTGTAAT 
TTCTGCCGGG ACTTGGACTT GTGCAAAGAC TCTGCCTTCT CTCAGGATGG GGCCATCTTG 
CCTCAGTGGC TCTGCTCCAA CTGTCAGGCC GCCTATGACT CATCTGTCAT CGAGATGGCC 
CTGGTGGAGG CCCTGCAGAG GAAGCTGATG GCCTTCACCC TGCAGGACCT GGTCTGTGTG 
AAGTGCCGTG GAGTGAAGGA GACCCACATG CCCGTGTACT GCAGCTGCGC TGGAGACTTC 
TCCCTCACCA TCCGCACTCA GATCTTCATG GAGCAGATTG GAATCTTCCA GAACATTGCC 
CAGCACTATG GCATGTCGTA TCTCATGGAA ACCTTGGAGT GGCTGATGCA GAAAAGCCCT 
CAGCTAGGCC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_012785308.1
CDS	76..6510
Translation	MDLRFGFERLKEPGEKTGWLINMHPTEILDEDKRLISAVDYYFIQDDGSRFKQSVLQGGGVITDEEEASKKIANQLDNIVDMREYDVPYHIRLSIDLKIHVAHWYNVRFRGNAFPVEIARRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKQEYEGPFCVFNEPDEVHLIQRWFEHIQETKPSIMVTYNGDFFDWPFVEARAAVHGLSMYQEIGFQKDNQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAYHANIIFPNKQEQEFNKLTDDGHVLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAFDSLLQRVEKTLRHAIEEEEKVPMEQVTNFQEVCDQIKTKLSSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPGANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANLITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTNAKKPKVTISYPGAMLNIMVKEGFTNHQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKTDVYKQKKISELFTLEGRRQVMLAQVPDSSPRPDTPDMEDFGLQKLPSSVVPVATKRKRILWESQEESQDPALIVPWQEILGQPPALGTTQEEWLVWLGFHKKKWQLQARQRMARRKKRRLEPEQGTSRPVAVRDGPATGLGSFLRRTARSVLDLPWQIVQISETSQAGFFRLWAIIGSDLHCIKLNISRVFYVNQRVAKAEEGPSYRKVNRFLPRSNMVYNLYEYSVPEELYQEHINEINTELSAPDIEGVYETQVPLLFRAIVQLGCVCVVNKQLARHLSGWETETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHSQGHKALFGIFIPSQRRASVFVLDTVRSNQMPNLSALYSAEHSLLLEKVGPDLLPPPKHTFEVRAETDLKTICRAIQRFLLAYKEERRGPTLVAIQSSWELKRLVGEIPILEEFPLVPVHVADKISYGVLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRHNHLLWLSPTARPDLGGKEADDSRLVMEFDDQATVEINNSGCYSTVCVELDMQNLAVNTILQSHHVNDMEGTDSVSVSFDAVAQASLEEMVTGIQATSTPASYDETALRPSTFRILKSMVVGWVKEITQYHNVYADNQVMHFYRWIRSPSSLLHDPALHRTLHNMMKKLFLQLISEFKRLGSSVVYANFNRIILCTKKRRIEDAIAYIEYITNSIHSKEIFHSLTISFSRCWEFLLWMDPSNYGGIKGKVSSRVHCGQVRASDPQEGEAVEDDEEEDSEEDDVEESQSDVEDLLENNWNILQFLPQAASCQSYFLMIVSAYIVAVYHSMKDELRRTAPGSTPVKKRNSSQLSQEAEGAAGALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTEPSDMFPVLPGSHLVLSNPALEFIKCVCKVLSLDTNITNQVNKLNRDLLRLVGVGEFSEEAQFRDPCRSYVLAEVICRSCNFCRDLDLCKDSAFSQDGAILPQWLCSNCQAAYDSSVIEMALVEALQRKLMAFTLQDLVCVKCRGVKETHMPVYCSCAGDFSLTIRTQIFMEQIGIFQNIAQHYGMSYLMETLEWLMQKSPQLGP

Target ORF information:

RefSeq Version	XM_012929854.1
Organism	Ochotona princeps(American pika)
Definition	Ochotona princeps polymerase (DNA directed), epsilon, catalytic subunit (POLE), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_012929854.1

ORF Insert Sequence:

ATGGACTTGC GGTTTGGATT TGAGAGGTTG AAAGAGCCTG GTGAGAAGAC GGGCTGGCTC 
ATCAACATGC ACCCTACTGA AATCTTAGAT GAAGATAAAC GCTTAATCAG TGCGGTGGAT 
TACTACTTTA TTCAAGATGA TGGGAGCAGA TTTAAGCAAA GTGTGTTGCA GGGGGGTGGT 
GTGATTACTG ATGAAGAGGA AGCCTCTAAG AAGATAGCCA ACCAACTGGA CAACATAGTG 
GACATGCGGG AGTATGACGT CCCCTATCAT ATCCGCCTCT CCATTGACCT CAAAATACAC 
GTGGCCCATT GGTATAACGT CAGATTCCGA GGAAACGCTT TTCCAGTGGA AATTGCCCGC 
CGAGATGACC TTGTTGAACG ACCTGACCCT GTGGTTCTGG CATTTGACAT CGAGACGACC 
AAACTACCCC TCAAATTTCC TGATGCTGAG ACGGACCAGA TCATGATGAT TTCTTACATG 
ATTGATGGCC AGGGCTACCT CATCACCAAC AGGGAGATTG TTTCAGAAGA CATTGAAGAC 
TTCGAGTTTA CCCCCAAGCA AGAATACGAG GGGCCCTTTT GTGTCTTCAA TGAACCTGAT 
GAGGTTCATC TGATCCAGAG GTGGTTTGAA CATATCCAGG AAACCAAACC CAGCATCATG 
GTCACCTACA ATGGAGACTT CTTTGATTGG CCATTTGTGG AGGCCAGGGC AGCAGTCCAT 
GGCCTGAGCA TGTATCAGGA GATCGGCTTC CAGAAGGACA ACCAGGGGGA GTACAAGGCG 
CCCCAGTGCA TCCACATGGA TTGTCTCAGG TGGGTGAAGA GAGACAGCTA TCTTCCTGTG 
GGCAGTCATA ATCTTAAGGC AGCTGCTAAG GCCAAGCTGG GCTATGACCC TGTAGAGCTG 
GACCCTGAGG ACATGTGCCG AATGGCCACT GAGCAACCCC AGACTCTGGC TACATATTCA 
GTGTCAGATG CTGTTGCTAC TTACTACCTG TACATGAAGT ATGTCCACCC TTTCATATTT 
GCCCTCTGCA CCATTATTCC CATGGAGCCC GATGAGGTGC TGCGGAAGGG CTCTGGCACG 
CTGTGCGAGG CCTTGCTGAT GGTGCAGGCC TACCATGCCA ACATCATCTT CCCCAACAAG 
CAGGAGCAAG AGTTCAACAA GCTGACAGAT GATGGCCATG TCCTGGACGC TGAGACCTAC 
GTTGGGGGGC ATGTGGAGGC GCTGGAATCT GGGGTCTTCC GAAGTGACAT CCCCTGCCGG 
TTTAGGATGA ATCCTGCCGC CTTTGACTCC CTGCTGCAGC GAGTTGAGAA GACCTTGCGT 
CATGCCATTG AAGAAGAGGA GAAGGTGCCA ATGGAGCAAG TCACCAACTT CCAGGAGGTG 
TGTGATCAGA TTAAGACCAA GCTTAGCTCC CTGAAAGATG TCCCTAACCG AATCGAGTGT 
CCCCTTATCT ACCACCTGGA TGTGGGAGCA ATGTACCCCA ACATTATCCT GACAAACCGC 
CTACAGCCCT CAGCCATGGT GGATGAGGCC ACCTGTGCTG CATGTGACTT CAACAAGCCT 
GGAGCCAACT GCCAGAGGAA GATGGCTTGG CAGTGGAGGG GCGAGTTTAT GCCTGCCAGT 
CGCAGTGAAT ATCATCGGAT TCAGCACCAG TTGGAGTCAG AAAAGTTTCC CCCCTTGTTC 
CCAGAGGGAC CCGCTCGAGC CTTTCACGAA CTGTCACGTG AGGAACAAGC TAAATATGAG 
AAGAGGAGGC TGGCAGATTA CTGCCGGAAA GCCTACAAAA AGATCCACAT CACTAAGGTG 
GAGGAGCGCC TCACCACCAT CTGCCAACGG GAGAACTCCT TCTACGTGGA CACAGTGCGA 
GCCTTTCGGG ACAGGCGCTA CGAGTTCAAA GGGCTTCACA AGGTGTGGAA AAAGAAGCTT 
TCAGCAGCTG TGGAGGTGGG TGACGCAGCT GAGGTGAAGC GCTGCAAGAA CATGGAGGTG 
CTGTATGACT CCCTGCAGCT GGCCCACAAG TGCATCCTCA ACTCCTTCTA CGGCTATGTT 
ATGCGCAAAG GAGCTCGCTG GTACTCCATG GAGATGGCTG GCATCGTCTG TTTCACAGGG 
GCCAACCTCA TCACTCAGGC CCGGGAGCTC ATTGAGCAGA TCGGGAGGCC CTTGGAACTG 
GACACAGATG GAATATGGTG TGTCCTGCCG AATAGCTTCC CAGAAAATTT TGTCATCAAG 
ACGACTAATG CGAAGAAGCC CAAGGTGACC ATTTCCTACC CTGGAGCCAT GTTGAACATC 
ATGGTCAAGG AAGGTTTCAC CAATCACCAG TACCAGGAGC TGGCAGAACC TTCCTCCCTC 
ACCTATGTCA CCCGCTCAGA GAACAGCATC TTTTTTGAGG TTGATGGGCC CTACCTCGCC 
ATGATCCTTC CAGCCTCCAA GGAAGAAGGC AAGAAACTGA AGAAGAGGTA TGCTGTGTTC 
AATGAAGATG GATCTCTGGC TGAGCTAAAG GGCTTTGAGG TGAAACGCCG TGGGGAGCTG 
CAGCTGATTA AAATCTTCCA GTCCTCGGTA TTTGAGGCCT TCCTCAAGGG TAGCACGCTG 
GAGGAGGTAT ACGGTTCTGT TGCCAAGGTG GCCGACTACT GGCTGGATGT GCTGTACAGT 
AAGGCTGCCA ACATGCCAGA TTCTGAGCTG TTCGAGCTCA TCTCCGAGAA CCGGTCCATG 
TCACGGAAGC TGGAAGACTA CGGGGAGCAG AAGTCCACGT CCATCAGCAC TGCCAAGCGC 
CTGGCCGAGT TCCTGGGAGA CCAGATGGTC AAGGACGCGG GCCTCAGCTG CCGCTATATC 
ATCTCCCGAA AGCCCGAGGG CTCTCCTGTC ACTGAGAGGG CCATCCCACT TGCCATTTTC 
CAAGCAGAGC CTACAGTAAG GAAGCACTTT CTCCGGAAAT GGCTTAAGAG CTCGTCTCTT 
CAGGACTTTG ATATTCGGAC AATCCTTGAC TGGGACTACT ACATCGAACG GCTGGGCAGT 
GCCATCCAGA AGATCATCAC CATCCCCGCC GCTCTGCAGC AGGTGAAGAA TCCTGTGCCA 
CGTGTGAAAC ACCCTGACTG GCTGCACAAA AAGCTGCTGG AGAAGACTGA TGTCTACAAG 
CAGAAGAAGA TCAGCGAGCT CTTCACTCTG GAGGGCAGGA GACAGGTTAT GTTGGCACAG 
GTCCCTGACA GCAGTCCAAG GCCAGACACT CCTGACATGG AGGACTTTGG CCTCCAAAAA 
TTGCCCTCCT CAGTGGTCCC TGTTGCAACC AAGAGGAAGC GAATCCTGTG GGAAAGCCAG 
GAGGAGTCTC AGGACCCAGC ATTGATTGTG CCCTGGCAGG AGATCTTGGG GCAGCCCCCT 
GCCCTTGGAA CCACCCAGGA GGAGTGGCTG GTCTGGCTCG GCTTCCACAA GAAGAAGTGG 
CAACTGCAGG CCCGGCAGCG CATGGCTCGC AGAAAGAAGC GGCGTTTAGA GCCAGAGCAG 
GGTACTTCGA GGCCTGTGGC CGTTCGAGAC GGGCCTGCCA CGGGGCTGGG GAGCTTCTTG 
CGAAGAACTG CCCGCAGTGT GCTGGACCTT CCGTGGCAGA TTGTGCAGAT CAGTGAGACC 
AGCCAGGCTG GCTTCTTCAG GCTGTGGGCC ATCATTGGCA GTGACTTGCA CTGCATCAAG 
CTGAATATTT CCCGTGTGTT CTATGTGAAC CAGCGAGTGG CCAAAGCAGA GGAGGGGCCT 
TCGTATCGAA AGGTGAATCG ATTCCTTCCT CGTTCCAACA TGGTCTACAA TCTCTATGAG 
TACTCAGTGC CAGAGGAGCT GTACCAAGAA CACATCAACG AAATCAATAC CGAGCTGTCA 
GCACCAGATA TTGAGGGTGT CTACGAGACT CAGGTTCCTT TGTTGTTCCG AGCCATTGTG 
CAGCTGGGCT GTGTGTGTGT CGTCAACAAG CAGCTGGCAA GGCACCTGTC AGGCTGGGAA 
ACCGAAACCT TTGCTCTGGA GCACCTGGAA ATGCGTTCTC TAGCTCAATT CAGCTACCTG 
GAGCCAGGGA GCATCCGCCA CATCTACCTC TACCACCACT CACAGGGCCA CAAAGCACTC 
TTTGGGATCT TCATCCCCTC ACAGCGCAGA GCGTCTGTAT TTGTGCTGGA CACGGTGCGC 
AGCAACCAAA TGCCCAATCT CAGTGCGCTC TACTCAGCGG AGCACAGCCT CCTGCTGGAG 
AAGGTGGGCC CCGATCTCCT GCCACCCCCA AAACACACCT TTGAAGTGCG CGCAGAGACA 
GACCTGAAGA CCATCTGCAG AGCCATACAG CGTTTTCTGC TCGCCTACAA GGAAGAGCGT 
CGAGGGCCTA CCCTAGTGGC CATCCAGTCC AGCTGGGAAC TGAAGCGGCT AGTAGGTGAG 
ATTCCTATCT TGGAGGAATT CCCACTGGTA CCTGTGCATG TGGCTGACAA GATCAGCTAT 
GGAGTCCTGG ACTGGCAGCG GCATGGAGCC CGACGAATGA TCCGACACTA CCTCAACCTC 
GACACGTGCT TGTCCCAGGC CTTTGAGATG AGCAGGTACT TTCACATTCC CATTGGGAAT 
CTGCCAGAGG ACATCTCCAC CTTTGGCTCT GACCTCTTCT TCGCACGCCA CCTCCAGCGC 
CACAACCACC TGCTCTGGTT GTCTCCTACA GCCCGCCCTG ACTTAGGCGG GAAGGAGGCT 
GACGACAGCC GCCTCGTCAT GGAGTTCGAT GATCAAGCCA CAGTGGAGAT CAACAATTCA 
GGCTGCTACT CCACGGTGTG TGTAGAGCTG GACATGCAGA ACCTGGCCGT CAACACCATC 
CTTCAGTCTC ACCACGTCAA CGACATGGAG GGGACTGACA GTGTGAGCGT CAGCTTCGAT 
GCAGTCGCCC AGGCCTCCCT TGAGGAAATG GTCACAGGCA TTCAAGCCAC CAGCACCCCA 
GCCAGCTATG ATGAGACTGC TCTCCGCCCC AGCACATTCA GGATTCTGAA GAGCATGGTG 
GTGGGCTGGG TCAAGGAGAT CACGCAGTAC CACAATGTGT ACGCGGACAA CCAGGTAATG 
CACTTTTACC GCTGGATCCG GTCACCGTCA TCCCTGCTCC ATGACCCTGC TCTTCACCGG 
ACTCTGCACA ACATGATGAA GAAGCTTTTC CTGCAGCTCA TCTCTGAGTT CAAGCGCCTG 
GGGTCTTCAG TTGTCTATGC CAACTTCAAC CGCATCATCC TCTGTACAAA AAAGCGCCGG 
ATTGAAGATG CTATTGCCTA CATAGAGTAC ATCACCAACA GTATCCACTC CAAAGAAATC 
TTCCATTCCC TGACAATTTC CTTCTCACGG TGCTGGGAAT TTCTTCTCTG GATGGATCCG 
TCCAACTATG GTGGAATCAA GGGCAAAGTG TCCTCCCGTG TTCACTGTGG ACAGGTGAGA 
GCTAGTGATC CTCAGGAAGG AGAGGCAGTG GAGGATGACG AGGAGGAAGA TTCAGAGGAG 
GACGATGTGG AGGAGTCCCA GTCCGATGTG GAGGACTTAC TAGAAAACAA CTGGAATATC 
CTGCAGTTCT TGCCCCAGGC AGCCTCCTGC CAAAGCTACT TCCTCATGAT TGTTTCAGCA 
TACATTGTGG CTGTGTACCA CAGCATGAAG GACGAGCTGA GGCGCACTGC CCCAGGGAGC 
ACCCCTGTGA AGAAGAGAAA CTCCAGCCAG CTCTCCCAGG AAGCTGAAGG GGCAGCTGGA 
GCCCTTCCTG GAATGATCAC CTTCTCTCAG GATTATGTGG CAAATGAGCT GACTCAGAGC 
TTTTTCACCA TAACCCAGAA AATCCAGAAG AAAGTCACAG GATCTCGGAA CTCGACAGAG 
CCTTCAGACA TGTTCCCTGT GCTCCCTGGT TCTCATTTGG TGCTCAGCAA TCCTGCTCTG 
GAGTTCATCA AATGCGTATG CAAGGTCCTG TCCCTGGACA CCAACATCAC TAACCAGGTG 
AATAAGCTGA ACCGAGACCT ACTGCGCCTG GTAGGTGTCG GCGAGTTCTC CGAGGAGGCC 
CAGTTCAGAG ACCCCTGCCG CTCCTATGTG CTCGCGGAGG TCATCTGCCG CAGCTGTAAT 
TTCTGCCGGG ACTTGGACTT GTGCAAAGAC TCTGCCTTCT CTCAGGATGG GGCCATCTTG 
CCTCAGTGGC TCTGCTCCAA CTGTCAGGCC GCCTATGACT CATCTGTCAT CGAGATGGCC 
CTGGTGGAGG CCCTGCAGAG GAAGCTGATG GCCTTCACCC TGCAGGACCT GGTCTGTGTG 
AAGTGCCGTG GAGTGAAGGA GACCCACATG CCCGTGTACT GCAGCTGCGC TGGAGACTTC 
TCCCTCACCA TCCGCACTCA GATCTTCATG GAGCAGATTG GAATCTTCCA GAACATTGCC 
CAGCACTATG GCATGTCGTA TCTCATGGAA ACCTTGGAGT GGCTGATGCA GAAAAGCCCT 
CAGCTAGGCC CCTAG