Pank1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pank1
Entrez Gene ID	75735
Full Name	pantothenate kinase 1
Synonyms	Pank,Pank1b
General protein information	Preferred Names pantothenate kinase 1 Names pantothenate kinase 1 pantothenic acid kinase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19 C1\|19

mRNA and Protein(s)

mRNA	Protein	Name
NM_001114339.2	NP_001107811.1	pantothenate kinase 1 isoform 1
NM_023792.2	NP_076281.1	pantothenate kinase 1 isoform 2
XM_006527427.4	XP_006527490.1	pantothenate kinase 1 isoform X1
XM_030251126.1	XP_030106986.1	pantothenate kinase 1 isoform X2
XM_006527427.3	XP_006527490.1	pantothenate kinase 1 isoform X1

Pathways from BioSystems

Homologies

	PANK1	XP_001087260.1
Bos taurus (cattle)	PANK1	XP_002698391.1
Rattus norvegicus (Norway rat)	Pank1	NP_001099843.1
Danio rerio (zebrafish)	pank1b	NP_001077310.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011715	XP_320797.3
Mus musculus (house mouse)	Pank1	NP_001107811.1
Pan troglodytes (chimpanzee)	PANK1	XP_001143095.1
Drosophila melanogaster (fruit fly)	fbl	NP_524870.1
Xenopus tropicalis (tropical clawed frog)	pank1	XP_004915939.1
Homo sapiens (human)	PANK1	NP_683878.1

Gene Ontology
Bibliography

Related articles in PubMed

Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.
Zano SP, Pate C, Frank M, Rock CO, Jackowski S
Molecular genetics and metabolism116(4)281-8(2015 Dec)

Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance.
Leonardi R, Rock CO, Jackowski S
Diabetologia57(7)1466-75(2014 Jul)

p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene.
Wang SJ, Yu G, Jiang L, Li T, Lin Q, Tang Y, Gu W
Cell cycle (Georgetown, Tex.)12(5)753-61(2013 Mar)

Identification of novel markers of mouse fetal ovary development.
Chen H, Palmer JS, Thiagarajan RD, Dinger ME, Lesieur E, Chiu H, Schulz A, Spiller C, Grimmond SM, Little MH, Koopman P, Wilhelm D
PloS one7(7)e41683(2012)

Compartmentalization of mammalian pantothenate kinases.
Alfonso-Pecchio A, Garcia M, Leonardi R, Jackowski S
PloS one7(11)e49509(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Pank1 genetic deficiency can be corrected using phosphopantothenate diet replacement therapy.
Title: Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.

The results indicate that Pank1 deficiency drives a whole-body metabolic adaptation that improves aspects of the diabetic phenotype and uncouples hyperglycaemia and hyperinsulinaemia from obesity in leptin-deficient mice.
Title: Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance.

p53 plays an important role in regulating energy homeostasis through transcriptional control of PANK1.
Title: p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene.

The data indicate that PanK1 and PanK2 can compensate for each other to supply tissue CoA.
Title: Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.

data illustrate the importance of PanK1 and elevated liver CoA levels during fasting to support the metabolic transition from glucose utilization and fatty acid synthesis to gluconeogenesis and fatty acid oxidation
Title: Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state.

The following Pank1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pank1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu14044	NM_023792.2 Latest version!	Mus musculus pantothenate kinase 1 (Pank1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu55794	XM_006527427.4 Latest version!	Mus musculus pantothenate kinase 1 (Pank1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu87628	XM_030251126.1 Latest version!	Mus musculus pantothenate kinase 1 (Pank1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu13781	NM_001114339.2 Latest version!	Mus musculus pantothenate kinase 1 (Pank1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$321.30 $459.00
View Old Accession Versions >>
OMu55794	XM_006527427.3	Mus musculus pantothenate kinase 1 (Pank1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pank1 ( NM_023792.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_076281.1 Mus musculus pantothenate kinase 1 (Pank1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu14044
Clone ID Related Accession (Same CDS sequence)	NM_023792.2
Accession Version	NM_023792.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Mus musculus(house mouse)
Product	pantothenate kinase 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF200357.1 and AC125259.8. On Nov 7, 2013 this sequence version replaced NM_023792.1. Transcript Variant: This variant (2) uses an alternate 5'-terminal exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2, also known as beta) has a shorter and distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF200357.1, AK050222.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTTG TAAATGGCAG AAAGCAAACA TTCCCGTGGT TTGGTATGGA TATCGGTGGA 
ACCCTGGTTA AGCTGGTTTA CTTTGAACCG AAGGATATCA CGGCAGAGGA AGAACAGGAA 
GAAGTGGAGA ACCTGAAGAG CATCCGGAAG TATTTAACTT CTAACACTGC CTACGGCAAA 
ACTGGGATCC GGGACGTCCA TCTGGAACTG AAAAACCTGA CCATGTGTGG GCGCAAAGGG 
AACCTGCACT TCATCCGCTT CCCGACCTGT GCCATGCACT TGTTCATCCA GATGGGCAGC 
GAGAAGAACT TCTCCAGCCT CCACACCACC CTCTGTGCCA CGGGAGGTGG GGCTTTCAAG 
TTTGAGGAGG ACTTCCGAAT GATTGCGGAC CTGCAGCTGC ATAAACTGGA TGAGCTGGAC 
TGTTTGATTC AGGGCCTTCT TTACGTTGAC TCGGTTGGCT TCAATGGCAA GCCAGAATGT 
TACTATTTCG AAAACCCCAC AAATCCCGAG TTGTGTCAAA AAAAGCCATA CTGTTTGGAT 
AACCCGTACC CTATGTTGCT GGTTAACATG GGCTCAGGCG TCAGCATCCT GGCAGTGTAC 
TCCAAGGACA ACTACAAAAG AGTGACGGGG ACCAGTCTTG GAGGTGGGAC ATTCCTAGGC 
CTATGTTGCT TGCTGACTGG TTGTGAGACC TTTGAAGAAG CTCTGGACAT GGCAGCTAAA 
GGCGACAGCA CCAATGTGGA TAAGCTGGTG AAGGACATTT ACGGAGGAGA CTATGAGCGA 
TTTGGCCTTC AAGGATCTGC TGTAGCATCA AGCTTTGGCA ACATGATGAG CAAAGAAAAG 
AGAGAGTCCA TCAGCAAAGA AGACCTCGCC CGGGCCACAT TGGTCACCAT CACCAACAAC 
ATTGGCTCCA TTGCTCGGAT GTGTGCACTG AATGAGAATA TTGACAGAGT TGTGTTTGTT 
GGGAACTTTC TCAGAATCAA TATGGTCTCA ATGAAGTTGC TAGCATATGC CATGGACTTT 
TGGTCTAAAG GACAGCTGAA AGCACTGTTT TTGGAACATG AGGGTTATTT TGGAGCTGTT 
GGGGCCCTGT TGGAACTGTT CAAAATGACC GATACACAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076281.1
CDS	205..1326
Translation	MKLVNGRKQTFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALDMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELFKMTDTQ

Target ORF information:

RefSeq Version	NM_023792.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus pantothenate kinase 1 (Pank1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023792.2

ORF Insert Sequence:

ATGAAGCTTG TAAATGGCAG AAAGCAAACA TTCCCGTGGT TTGGTATGGA TATCGGTGGA 
ACCCTGGTTA AGCTGGTTTA CTTTGAACCG AAGGATATCA CGGCAGAGGA AGAACAGGAA 
GAAGTGGAGA ACCTGAAGAG CATCCGGAAG TATTTAACTT CTAACACTGC CTACGGCAAA 
ACTGGGATCC GGGACGTCCA TCTGGAACTG AAAAACCTGA CCATGTGTGG GCGCAAAGGG 
AACCTGCACT TCATCCGCTT CCCGACCTGT GCCATGCACT TGTTCATCCA GATGGGCAGC 
GAGAAGAACT TCTCCAGCCT CCACACCACC CTCTGTGCCA CGGGAGGTGG GGCTTTCAAG 
TTTGAGGAGG ACTTCCGAAT GATTGCGGAC CTGCAGCTGC ATAAACTGGA TGAGCTGGAC 
TGTTTGATTC AGGGCCTTCT TTACGTTGAC TCGGTTGGCT TCAATGGCAA GCCAGAATGT 
TACTATTTCG AAAACCCCAC AAATCCCGAG TTGTGTCAAA AAAAGCCATA CTGTTTGGAT 
AACCCGTACC CTATGTTGCT GGTTAACATG GGCTCAGGCG TCAGCATCCT GGCAGTGTAC 
TCCAAGGACA ACTACAAAAG AGTGACGGGG ACCAGTCTTG GAGGTGGGAC ATTCCTAGGC 
CTATGTTGCT TGCTGACTGG TTGTGAGACC TTTGAAGAAG CTCTGGACAT GGCAGCTAAA 
GGCGACAGCA CCAATGTGGA TAAGCTGGTG AAGGACATTT ACGGAGGAGA CTATGAGCGA 
TTTGGCCTTC AAGGATCTGC TGTAGCATCA AGCTTTGGCA ACATGATGAG CAAAGAAAAG 
AGAGAGTCCA TCAGCAAAGA AGACCTCGCC CGGGCCACAT TGGTCACCAT CACCAACAAC 
ATTGGCTCCA TTGCTCGGAT GTGTGCACTG AATGAGAATA TTGACAGAGT TGTGTTTGTT 
GGGAACTTTC TCAGAATCAA TATGGTCTCA ATGAAGTTGC TAGCATATGC CATGGACTTT 
TGGTCTAAAG GACAGCTGAA AGCACTGTTT TTGGAACATG AGGGTTATTT TGGAGCTGTT 
GGGGCCCTGT TGGAACTGTT CAAAATGACC GATACACAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pank1 ( XM_006527427.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006527490.1 Mus musculus pantothenate kinase 1 (Pank1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu55794
Clone ID Related Accession (Same CDS sequence)	XM_006527427.4 , XM_006527427.3
Accession Version	XM_006527427.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	pantothenate kinase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006527427.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGGGGA GGCGGGCTCC CCGGCCGGGG TCCACCGAGG TTCCCGCAGC TGCGCGCGAT 
GCCGACACGC TGCGGGCGAG AGCAGCAAGC CCGGTGCGCG GGGCCCAGCT CGCCGAAGAC 
GTGGGGACGC CGACGGGAGG AGGGGAGGAG CGCCGGGGCC ACCAGCTCCC GACCGCGGCG 
CCGAGGCTGC GGGAGAGCAA GCCCCAGGGT GGATCGGAAG ATCGGGGAAC GGCCGACCGT 
GACCTCCAGC GAGGCTGCCA GAGCCGGAGC CCGCGCACCG CTCCGCCGGT CCCGGGCATG 
GGCGACCGCG GCGCGCAACA CGAGCGCGCG GCCCTGCAGT CCCCGGGGGC CCCCGAGGGC 
GCCGCGGCCG CCGTGAACGG GCTGCTGCAC AACGGCTTCC ACCCGTCGGC CGCCAGCAGC 
CGCGACCCGC CGGCCCCACG CTTCCAGCTC CCGTCCGAGC TGCAGCCGCA GCCGCTGTTC 
GCCCAGCATG ATTCTCCGGC CAAGAAATGC CGGCTGCGGA GGAGGATGGA CTCCGGGAGG 
AAGAACAGGC CGCCATTCCC GTGGTTTGGT ATGGATATCG GTGGAACCCT GGTTAAGCTG 
GTTTACTTTG AACCGAAGGA TATCACGGCA GAGGAAGAAC AGGAAGAAGT GGAGAACCTG 
AAGAGCATCC GGAAGTATTT AACTTCTAAC ACTGCCTACG GCAAAACTGG GATCCGGGAC 
GTCCATCTGG AACTGAAAAA CCTGACCATG TGTGGGCGCA AAGGGAACCT GCACTTCATC 
CGCTTCCCGA CCTGTGCCAT GCACTTGTTC ATCCAGATGG GCAGCGAGAA GAACTTCTCC 
AGCCTCCACA CCACCCTCTG TGCCACGGGA GGTGGGGCTT TCAAGTTTGA GGAGGACTTC 
CGAATGATTG CGGACCTGCA GCTGCATAAA CTGGATGAGC TGGACTGTTT GATTCAGGGC 
CTTCTTTACG TTGACTCGGT TGGCTTCAAT GGCAAGCCAG AATGTTACTA TTTCGAAAAC 
CCCACAAATC CCGAGTTGTG TCAAAAAAAG CCATACTGTT TGGATAACCC GTACCCTATG 
TTGCTGGTTA ACATGGGCTC AGGCGTCAGC ATCCTGGCAG TGTACTCCAA GGACAACTAC 
AAAAGAGTGA CGGGGACCAG CTTTGGCAAC ATGATGAGCA AAGAAAAGAG AGAGTCCATC 
AGCAAAGAAG ACCTCGCCCG GGCCACATTG GTCACCATCA CCAACAACAT TGGCTCCATT 
GCTCGGATGT GTGCACTGAA TGAGAATATT GACAGAGTTG TGTTTGTTGG GAACTTTCTC 
AGAATCAATA TGGTCTCAAT GAAGTTGCTA GCATATGCCA TGGACTTTTG GTCTAAAGGA 
CAGCTGAAAG CACTGTTTTT GGAACATGAG GGTTATTTTG GAGCTGTTGG GGCCCTGTTG 
GAACTGTTCA AAATGACCGA TACACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006527490.1
CDS	4348..5817
Translation	MRGRRAPRPGSTEVPAAARDADTLRARAASPVRGAQLAEDVGTPTGGGEERRGHQLPTAAPRLRESKPQGGSEDRGTADRDLQRGCQSRSPRTAPPVPGMGDRGAQHERAALQSPGAPEGAAAAVNGLLHNGFHPSAASSRDPPAPRFQLPSELQPQPLFAQHDSPAKKCRLRRRMDSGRKNRPPFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELFKMTDTQ

Target ORF information:

RefSeq Version	XM_006527427.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus pantothenate kinase 1 (Pank1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006527427.4

ORF Insert Sequence:

ATGAGGGGGA GGCGGGCTCC CCGGCCGGGG TCCACCGAGG TTCCCGCAGC TGCGCGCGAT 
GCCGACACGC TGCGGGCGAG AGCAGCAAGC CCGGTGCGCG GGGCCCAGCT CGCCGAAGAC 
GTGGGGACGC CGACGGGAGG AGGGGAGGAG CGCCGGGGCC ACCAGCTCCC GACCGCGGCG 
CCGAGGCTGC GGGAGAGCAA GCCCCAGGGT GGATCGGAAG ATCGGGGAAC GGCCGACCGT 
GACCTCCAGC GAGGCTGCCA GAGCCGGAGC CCGCGCACCG CTCCGCCGGT CCCGGGCATG 
GGCGACCGCG GCGCGCAACA CGAGCGCGCG GCCCTGCAGT CCCCGGGGGC CCCCGAGGGC 
GCCGCGGCCG CCGTGAACGG GCTGCTGCAC AACGGCTTCC ACCCGTCGGC CGCCAGCAGC 
CGCGACCCGC CGGCCCCACG CTTCCAGCTC CCGTCCGAGC TGCAGCCGCA GCCGCTGTTC 
GCCCAGCATG ATTCTCCGGC CAAGAAATGC CGGCTGCGGA GGAGGATGGA CTCCGGGAGG 
AAGAACAGGC CGCCATTCCC GTGGTTTGGT ATGGATATCG GTGGAACCCT GGTTAAGCTG 
GTTTACTTTG AACCGAAGGA TATCACGGCA GAGGAAGAAC AGGAAGAAGT GGAGAACCTG 
AAGAGCATCC GGAAGTATTT AACTTCTAAC ACTGCCTACG GCAAAACTGG GATCCGGGAC 
GTCCATCTGG AACTGAAAAA CCTGACCATG TGTGGGCGCA AAGGGAACCT GCACTTCATC 
CGCTTCCCGA CCTGTGCCAT GCACTTGTTC ATCCAGATGG GCAGCGAGAA GAACTTCTCC 
AGCCTCCACA CCACCCTCTG TGCCACGGGA GGTGGGGCTT TCAAGTTTGA GGAGGACTTC 
CGAATGATTG CGGACCTGCA GCTGCATAAA CTGGATGAGC TGGACTGTTT GATTCAGGGC 
CTTCTTTACG TTGACTCGGT TGGCTTCAAT GGCAAGCCAG AATGTTACTA TTTCGAAAAC 
CCCACAAATC CCGAGTTGTG TCAAAAAAAG CCATACTGTT TGGATAACCC GTACCCTATG 
TTGCTGGTTA ACATGGGCTC AGGCGTCAGC ATCCTGGCAG TGTACTCCAA GGACAACTAC 
AAAAGAGTGA CGGGGACCAG CTTTGGCAAC ATGATGAGCA AAGAAAAGAG AGAGTCCATC 
AGCAAAGAAG ACCTCGCCCG GGCCACATTG GTCACCATCA CCAACAACAT TGGCTCCATT 
GCTCGGATGT GTGCACTGAA TGAGAATATT GACAGAGTTG TGTTTGTTGG GAACTTTCTC 
AGAATCAATA TGGTCTCAAT GAAGTTGCTA GCATATGCCA TGGACTTTTG GTCTAAAGGA 
CAGCTGAAAG CACTGTTTTT GGAACATGAG GGTTATTTTG GAGCTGTTGG GGCCCTGTTG 
GAACTGTTCA AAATGACCGA TACACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pank1 ( XM_030251126.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106986.1 Mus musculus pantothenate kinase 1 (Pank1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu87628
Clone ID Related Accession (Same CDS sequence)	XM_030251126.1
Accession Version	XM_030251126.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	pantothenate kinase 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTTG TAAATGGCAG AAAGCAAACA TTCCCGTGGT TTGGTATGGA TATCGGTGGA 
ACCCTGGTTA AGCTGGTTTA CTTTGAACCG AAGGATATCA CGGCAGAGGA AGAACAGGAA 
GAAGTGGAGA ACCTGAAGAG CATCCGGAAG TATTTAACTT CTAACACTGC CTACGGCAAA 
ACTGGGATCC GGGACGTCCA TCTGGAACTG AAAAACCTGA CCATGTGTGG GCGCAAAGGG 
AACCTGCACT TCATCCGCTT CCCGACCTGT GCCATGCACT TGTTCATCCA GATGGGCAGC 
GAGAAGAACT TCTCCAGCCT CCACACCACC CTCTGTGCCA CGGGAGGTGG GGCTTTCAAG 
TTTGAGGAGG ACTTCCGAAT GATTGCGGAC CTGCAGCTGC ATAAACTGGA TGAGCTGGAC 
TGTTTGATTC AGGGCCTTCT TTACGTTGAC TCGGTTGGCT TCAATGGCAA GCCAGAATGT 
TACTATTTCG AAAACCCCAC AAATCCCGAG TTGTGTCAAA AAAAGCCATA CTGTTTGGAT 
AACCCGTACC CTATGTTGCT GGTTAACATG GGCTCAGGCG TCAGCATCCT GGCAGTGTAC 
TCCAAGGACA ACTACAAAAG AGTGACGGGG ACCAGCTTTG GCAACATGAT GAGCAAAGAA 
AAGAGAGAGT CCATCAGCAA AGAAGACCTC GCCCGGGCCA CATTGGTCAC CATCACCAAC 
AACATTGGCT CCATTGCTCG GATGTGTGCA CTGAATGAGA ATATTGACAG AGTTGTGTTT 
GTTGGGAACT TTCTCAGAAT CAATATGGTC TCAATGAAGT TGCTAGCATA TGCCATGGAC 
TTTTGGTCTA AAGGACAGCT GAAAGCACTG TTTTTGGAAC ATGAGGGTTA TTTTGGAGCT 
GTTGGGGCCC TGTTGGAACT GTTCAAAATG ACCGATACAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106986.1
CDS	5711..6655
Translation	MKLVNGRKQTFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELFKMTDTQ

Target ORF information:

RefSeq Version	XM_030251126.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus pantothenate kinase 1 (Pank1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030251126.1

ORF Insert Sequence:

ATGAAGCTTG TAAATGGCAG AAAGCAAACA TTCCCGTGGT TTGGTATGGA TATCGGTGGA 
ACCCTGGTTA AGCTGGTTTA CTTTGAACCG AAGGATATCA CGGCAGAGGA AGAACAGGAA 
GAAGTGGAGA ACCTGAAGAG CATCCGGAAG TATTTAACTT CTAACACTGC CTACGGCAAA 
ACTGGGATCC GGGACGTCCA TCTGGAACTG AAAAACCTGA CCATGTGTGG GCGCAAAGGG 
AACCTGCACT TCATCCGCTT CCCGACCTGT GCCATGCACT TGTTCATCCA GATGGGCAGC 
GAGAAGAACT TCTCCAGCCT CCACACCACC CTCTGTGCCA CGGGAGGTGG GGCTTTCAAG 
TTTGAGGAGG ACTTCCGAAT GATTGCGGAC CTGCAGCTGC ATAAACTGGA TGAGCTGGAC 
TGTTTGATTC AGGGCCTTCT TTACGTTGAC TCGGTTGGCT TCAATGGCAA GCCAGAATGT 
TACTATTTCG AAAACCCCAC AAATCCCGAG TTGTGTCAAA AAAAGCCATA CTGTTTGGAT 
AACCCGTACC CTATGTTGCT GGTTAACATG GGCTCAGGCG TCAGCATCCT GGCAGTGTAC 
TCCAAGGACA ACTACAAAAG AGTGACGGGG ACCAGCTTTG GCAACATGAT GAGCAAAGAA 
AAGAGAGAGT CCATCAGCAA AGAAGACCTC GCCCGGGCCA CATTGGTCAC CATCACCAAC 
AACATTGGCT CCATTGCTCG GATGTGTGCA CTGAATGAGA ATATTGACAG AGTTGTGTTT 
GTTGGGAACT TTCTCAGAAT CAATATGGTC TCAATGAAGT TGCTAGCATA TGCCATGGAC 
TTTTGGTCTA AAGGACAGCT GAAAGCACTG TTTTTGGAAC ATGAGGGTTA TTTTGGAGCT 
GTTGGGGCCC TGTTGGAACT GTTCAAAATG ACCGATACAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pank1 ( NM_001114339.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001107811.1 Mus musculus pantothenate kinase 1 (Pank1), transcript variant 1, mRNA.

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CloneID	OMu13781
Clone ID Related Accession (Same CDS sequence)	NM_001114339.2
Accession Version	NM_001114339.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Mus musculus(house mouse)
Product	pantothenate kinase 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113244.19, AK017345.1, AF200357.1 and AC125259.8. On Nov 7, 2013 this sequence version replaced NM_001114339.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1, also known as alpha). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF347700.1, AK017345.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGGGGA GGCGGGCTCC CCGGCCGGGG TCCACCGAGG TTCCCGCAGC TGCGCGCGAT 
GCCGACACGC TGCGGGCGAG AGCAGCAAGC CCGGTGCGCG GGGCCCAGCT CGCCGAAGAC 
GTGGGGACGC CGACGGGAGG AGGGGAGGAG CGCCGGGGCC ACCAGCTCCC GACCGCGGCG 
CCGAGGCTGC GGGAGAGCAA GCCCCAGGGT GGATCGGAAG ATCGGGGAAC GGCCGACCGT 
GACCTCCAGC GAGGCTGCCA GAGCCGGAGC CCGCGCACCG CTCCGCCGGT CCCGGGCATG 
GGCGACCGCG GCGCGCAACA CGAGCGCGCG GCCCTGCAGT CCCCGGGGGC CCCCGAGGGC 
GCCGCGGCCG CCGTGAACGG GCTGCTGCAC AACGGCTTCC ACCCGTCGGC CGCCAGCAGC 
CGCGACCCGC CGGCCCCACG CTTCCAGCTC CCGTCCGAGC TGCAGCCGCA GCCGCTGTTC 
GCCCAGCATG ATTCTCCGGC CAAGAAATGC CGGCTGCGGA GGAGGATGGA CTCCGGGAGG 
AAGAACAGGC CGCCATTCCC GTGGTTTGGT ATGGATATCG GTGGAACCCT GGTTAAGCTG 
GTTTACTTTG AACCGAAGGA TATCACGGCA GAGGAAGAAC AGGAAGAAGT GGAGAACCTG 
AAGAGCATCC GGAAGTATTT AACTTCTAAC ACTGCCTACG GCAAAACTGG GATCCGGGAC 
GTCCATCTGG AACTGAAAAA CCTGACCATG TGTGGGCGCA AAGGGAACCT GCACTTCATC 
CGCTTCCCGA CCTGTGCCAT GCACTTGTTC ATCCAGATGG GCAGCGAGAA GAACTTCTCC 
AGCCTCCACA CCACCCTCTG TGCCACGGGA GGTGGGGCTT TCAAGTTTGA GGAGGACTTC 
CGAATGATTG CGGACCTGCA GCTGCATAAA CTGGATGAGC TGGACTGTTT GATTCAGGGC 
CTTCTTTACG TTGACTCGGT TGGCTTCAAT GGCAAGCCAG AATGTTACTA TTTCGAAAAC 
CCCACAAATC CCGAGTTGTG TCAAAAAAAG CCATACTGTT TGGATAACCC GTACCCTATG 
TTGCTGGTTA ACATGGGCTC AGGCGTCAGC ATCCTGGCAG TGTACTCCAA GGACAACTAC 
AAAAGAGTGA CGGGGACCAG TCTTGGAGGT GGGACATTCC TAGGCCTATG TTGCTTGCTG 
ACTGGTTGTG AGACCTTTGA AGAAGCTCTG GACATGGCAG CTAAAGGCGA CAGCACCAAT 
GTGGATAAGC TGGTGAAGGA CATTTACGGA GGAGACTATG AGCGATTTGG CCTTCAAGGA 
TCTGCTGTAG CATCAAGCTT TGGCAACATG ATGAGCAAAG AAAAGAGAGA GTCCATCAGC 
AAAGAAGACC TCGCCCGGGC CACATTGGTC ACCATCACCA ACAACATTGG CTCCATTGCT 
CGGATGTGTG CACTGAATGA GAATATTGAC AGAGTTGTGT TTGTTGGGAA CTTTCTCAGA 
ATCAATATGG TCTCAATGAA GTTGCTAGCA TATGCCATGG ACTTTTGGTC TAAAGGACAG 
CTGAAAGCAC TGTTTTTGGA ACATGAGGGT TATTTTGGAG CTGTTGGGGC CCTGTTGGAA 
CTGTTCAAAA TGACCGATAC ACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001107811.1
CDS	380..2026
Translation	MRGRRAPRPGSTEVPAAARDADTLRARAASPVRGAQLAEDVGTPTGGGEERRGHQLPTAAPRLRESKPQGGSEDRGTADRDLQRGCQSRSPRTAPPVPGMGDRGAQHERAALQSPGAPEGAAAAVNGLLHNGFHPSAASSRDPPAPRFQLPSELQPQPLFAQHDSPAKKCRLRRRMDSGRKNRPPFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALDMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELFKMTDTQ

Target ORF information:

RefSeq Version	NM_001114339.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus pantothenate kinase 1 (Pank1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001114339.2

ORF Insert Sequence:

ATGAGGGGGA GGCGGGCTCC CCGGCCGGGG TCCACCGAGG TTCCCGCAGC TGCGCGCGAT 
GCCGACACGC TGCGGGCGAG AGCAGCAAGC CCGGTGCGCG GGGCCCAGCT CGCCGAAGAC 
GTGGGGACGC CGACGGGAGG AGGGGAGGAG CGCCGGGGCC ACCAGCTCCC GACCGCGGCG 
CCGAGGCTGC GGGAGAGCAA GCCCCAGGGT GGATCGGAAG ATCGGGGAAC GGCCGACCGT 
GACCTCCAGC GAGGCTGCCA GAGCCGGAGC CCGCGCACCG CTCCGCCGGT CCCGGGCATG 
GGCGACCGCG GCGCGCAACA CGAGCGCGCG GCCCTGCAGT CCCCGGGGGC CCCCGAGGGC 
GCCGCGGCCG CCGTGAACGG GCTGCTGCAC AACGGCTTCC ACCCGTCGGC CGCCAGCAGC 
CGCGACCCGC CGGCCCCACG CTTCCAGCTC CCGTCCGAGC TGCAGCCGCA GCCGCTGTTC 
GCCCAGCATG ATTCTCCGGC CAAGAAATGC CGGCTGCGGA GGAGGATGGA CTCCGGGAGG 
AAGAACAGGC CGCCATTCCC GTGGTTTGGT ATGGATATCG GTGGAACCCT GGTTAAGCTG 
GTTTACTTTG AACCGAAGGA TATCACGGCA GAGGAAGAAC AGGAAGAAGT GGAGAACCTG 
AAGAGCATCC GGAAGTATTT AACTTCTAAC ACTGCCTACG GCAAAACTGG GATCCGGGAC 
GTCCATCTGG AACTGAAAAA CCTGACCATG TGTGGGCGCA AAGGGAACCT GCACTTCATC 
CGCTTCCCGA CCTGTGCCAT GCACTTGTTC ATCCAGATGG GCAGCGAGAA GAACTTCTCC 
AGCCTCCACA CCACCCTCTG TGCCACGGGA GGTGGGGCTT TCAAGTTTGA GGAGGACTTC 
CGAATGATTG CGGACCTGCA GCTGCATAAA CTGGATGAGC TGGACTGTTT GATTCAGGGC 
CTTCTTTACG TTGACTCGGT TGGCTTCAAT GGCAAGCCAG AATGTTACTA TTTCGAAAAC 
CCCACAAATC CCGAGTTGTG TCAAAAAAAG CCATACTGTT TGGATAACCC GTACCCTATG 
TTGCTGGTTA ACATGGGCTC AGGCGTCAGC ATCCTGGCAG TGTACTCCAA GGACAACTAC 
AAAAGAGTGA CGGGGACCAG TCTTGGAGGT GGGACATTCC TAGGCCTATG TTGCTTGCTG 
ACTGGTTGTG AGACCTTTGA AGAAGCTCTG GACATGGCAG CTAAAGGCGA CAGCACCAAT 
GTGGATAAGC TGGTGAAGGA CATTTACGGA GGAGACTATG AGCGATTTGG CCTTCAAGGA 
TCTGCTGTAG CATCAAGCTT TGGCAACATG ATGAGCAAAG AAAAGAGAGA GTCCATCAGC 
AAAGAAGACC TCGCCCGGGC CACATTGGTC ACCATCACCA ACAACATTGG CTCCATTGCT 
CGGATGTGTG CACTGAATGA GAATATTGAC AGAGTTGTGT TTGTTGGGAA CTTTCTCAGA 
ATCAATATGG TCTCAATGAA GTTGCTAGCA TATGCCATGG ACTTTTGGTC TAAAGGACAG 
CTGAAAGCAC TGTTTTTGGA ACATGAGGGT TATTTTGGAG CTGTTGGGGC CCTGTTGGAA 
CTGTTCAAAA TGACCGATAC ACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pank1 ( XM_006527427.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006527490.1 Mus musculus pantothenate kinase 1 (Pank1), transcript variant X1, mRNA.

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CloneID	OMu55794
Clone ID Related Accession (Same CDS sequence)	XM_006527427.4 , XM_006527427.3
Accession Version	XM_006527427.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	pantothenate kinase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006527427.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGGGGA GGCGGGCTCC CCGGCCGGGG TCCACCGAGG TTCCCGCAGC TGCGCGCGAT 
GCCGACACGC TGCGGGCGAG AGCAGCAAGC CCGGTGCGCG GGGCCCAGCT CGCCGAAGAC 
GTGGGGACGC CGACGGGAGG AGGGGAGGAG CGCCGGGGCC ACCAGCTCCC GACCGCGGCG 
CCGAGGCTGC GGGAGAGCAA GCCCCAGGGT GGATCGGAAG ATCGGGGAAC GGCCGACCGT 
GACCTCCAGC GAGGCTGCCA GAGCCGGAGC CCGCGCACCG CTCCGCCGGT CCCGGGCATG 
GGCGACCGCG GCGCGCAACA CGAGCGCGCG GCCCTGCAGT CCCCGGGGGC CCCCGAGGGC 
GCCGCGGCCG CCGTGAACGG GCTGCTGCAC AACGGCTTCC ACCCGTCGGC CGCCAGCAGC 
CGCGACCCGC CGGCCCCACG CTTCCAGCTC CCGTCCGAGC TGCAGCCGCA GCCGCTGTTC 
GCCCAGCATG ATTCTCCGGC CAAGAAATGC CGGCTGCGGA GGAGGATGGA CTCCGGGAGG 
AAGAACAGGC CGCCATTCCC GTGGTTTGGT ATGGATATCG GTGGAACCCT GGTTAAGCTG 
GTTTACTTTG AACCGAAGGA TATCACGGCA GAGGAAGAAC AGGAAGAAGT GGAGAACCTG 
AAGAGCATCC GGAAGTATTT AACTTCTAAC ACTGCCTACG GCAAAACTGG GATCCGGGAC 
GTCCATCTGG AACTGAAAAA CCTGACCATG TGTGGGCGCA AAGGGAACCT GCACTTCATC 
CGCTTCCCGA CCTGTGCCAT GCACTTGTTC ATCCAGATGG GCAGCGAGAA GAACTTCTCC 
AGCCTCCACA CCACCCTCTG TGCCACGGGA GGTGGGGCTT TCAAGTTTGA GGAGGACTTC 
CGAATGATTG CGGACCTGCA GCTGCATAAA CTGGATGAGC TGGACTGTTT GATTCAGGGC 
CTTCTTTACG TTGACTCGGT TGGCTTCAAT GGCAAGCCAG AATGTTACTA TTTCGAAAAC 
CCCACAAATC CCGAGTTGTG TCAAAAAAAG CCATACTGTT TGGATAACCC GTACCCTATG 
TTGCTGGTTA ACATGGGCTC AGGCGTCAGC ATCCTGGCAG TGTACTCCAA GGACAACTAC 
AAAAGAGTGA CGGGGACCAG CTTTGGCAAC ATGATGAGCA AAGAAAAGAG AGAGTCCATC 
AGCAAAGAAG ACCTCGCCCG GGCCACATTG GTCACCATCA CCAACAACAT TGGCTCCATT 
GCTCGGATGT GTGCACTGAA TGAGAATATT GACAGAGTTG TGTTTGTTGG GAACTTTCTC 
AGAATCAATA TGGTCTCAAT GAAGTTGCTA GCATATGCCA TGGACTTTTG GTCTAAAGGA 
CAGCTGAAAG CACTGTTTTT GGAACATGAG GGTTATTTTG GAGCTGTTGG GGCCCTGTTG 
GAACTGTTCA AAATGACCGA TACACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006527490.1
CDS	518..1987
Translation	MRGRRAPRPGSTEVPAAARDADTLRARAASPVRGAQLAEDVGTPTGGGEERRGHQLPTAAPRLRESKPQGGSEDRGTADRDLQRGCQSRSPRTAPPVPGMGDRGAQHERAALQSPGAPEGAAAAVNGLLHNGFHPSAASSRDPPAPRFQLPSELQPQPLFAQHDSPAKKCRLRRRMDSGRKNRPPFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSFGNMMSKEKRESISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALLELFKMTDTQ

Target ORF information:

RefSeq Version	XM_006527427.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus pantothenate kinase 1 (Pank1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006527427.3

ORF Insert Sequence:

ATGAGGGGGA GGCGGGCTCC CCGGCCGGGG TCCACCGAGG TTCCCGCAGC TGCGCGCGAT 
GCCGACACGC TGCGGGCGAG AGCAGCAAGC CCGGTGCGCG GGGCCCAGCT CGCCGAAGAC 
GTGGGGACGC CGACGGGAGG AGGGGAGGAG CGCCGGGGCC ACCAGCTCCC GACCGCGGCG 
CCGAGGCTGC GGGAGAGCAA GCCCCAGGGT GGATCGGAAG ATCGGGGAAC GGCCGACCGT 
GACCTCCAGC GAGGCTGCCA GAGCCGGAGC CCGCGCACCG CTCCGCCGGT CCCGGGCATG 
GGCGACCGCG GCGCGCAACA CGAGCGCGCG GCCCTGCAGT CCCCGGGGGC CCCCGAGGGC 
GCCGCGGCCG CCGTGAACGG GCTGCTGCAC AACGGCTTCC ACCCGTCGGC CGCCAGCAGC 
CGCGACCCGC CGGCCCCACG CTTCCAGCTC CCGTCCGAGC TGCAGCCGCA GCCGCTGTTC 
GCCCAGCATG ATTCTCCGGC CAAGAAATGC CGGCTGCGGA GGAGGATGGA CTCCGGGAGG 
AAGAACAGGC CGCCATTCCC GTGGTTTGGT ATGGATATCG GTGGAACCCT GGTTAAGCTG 
GTTTACTTTG AACCGAAGGA TATCACGGCA GAGGAAGAAC AGGAAGAAGT GGAGAACCTG 
AAGAGCATCC GGAAGTATTT AACTTCTAAC ACTGCCTACG GCAAAACTGG GATCCGGGAC 
GTCCATCTGG AACTGAAAAA CCTGACCATG TGTGGGCGCA AAGGGAACCT GCACTTCATC 
CGCTTCCCGA CCTGTGCCAT GCACTTGTTC ATCCAGATGG GCAGCGAGAA GAACTTCTCC 
AGCCTCCACA CCACCCTCTG TGCCACGGGA GGTGGGGCTT TCAAGTTTGA GGAGGACTTC 
CGAATGATTG CGGACCTGCA GCTGCATAAA CTGGATGAGC TGGACTGTTT GATTCAGGGC 
CTTCTTTACG TTGACTCGGT TGGCTTCAAT GGCAAGCCAG AATGTTACTA TTTCGAAAAC 
CCCACAAATC CCGAGTTGTG TCAAAAAAAG CCATACTGTT TGGATAACCC GTACCCTATG 
TTGCTGGTTA ACATGGGCTC AGGCGTCAGC ATCCTGGCAG TGTACTCCAA GGACAACTAC 
AAAAGAGTGA CGGGGACCAG CTTTGGCAAC ATGATGAGCA AAGAAAAGAG AGAGTCCATC 
AGCAAAGAAG ACCTCGCCCG GGCCACATTG GTCACCATCA CCAACAACAT TGGCTCCATT 
GCTCGGATGT GTGCACTGAA TGAGAATATT GACAGAGTTG TGTTTGTTGG GAACTTTCTC 
AGAATCAATA TGGTCTCAAT GAAGTTGCTA GCATATGCCA TGGACTTTTG GTCTAAAGGA 
CAGCTGAAAG CACTGTTTTT GGAACATGAG GGTTATTTTG GAGCTGTTGG GGCCCTGTTG 
GAACTGTTCA AAATGACCGA TACACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.
Molecular genetics and metabolism116(4)281-8(2015 Dec)
Zano SP,Pate C,Frank M,Rock CO,Jackowski S

Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance.
Diabetologia57(7)1466-75(2014 Jul)
Leonardi R,Rock CO,Jackowski S

p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene.
Cell cycle (Georgetown, Tex.)12(5)753-61(2013 Mar)
Wang SJ,Yu G,Jiang L,Li T,Lin Q,Tang Y,Gu W

Identification of novel markers of mouse fetal ovary development.
PloS one7(7)e41683(2012)
Chen H,Palmer JS,Thiagarajan RD,Dinger ME,Lesieur E,Chiu H,Schulz A,Spiller C,Grimmond SM,Little MH,Koopman P,Wilhelm D

Compartmentalization of mammalian pantothenate kinases.
PloS one7(11)e49509(2012)
Alfonso-Pecchio A,Garcia M,Leonardi R,Jackowski S

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Pank1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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