Chp2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Chp2
Entrez Gene ID	70261
Full Name	calcineurin-like EF hand protein 2
Synonyms	2010110P09Rik,Cbhp2
General protein information	Preferred Names calcineurin-like EF hand protein 2 Names calcineurin B homologous protein 2 hepatocellular carcinoma-associated antigen 520 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F2

mRNA and Protein(s)

mRNA	Protein	Name
XM_011241899.1	XP_011240201.1	calcineurin B homologous protein 2 isoform X1
NM_027363.1	NP_081639.1	calcineurin B homologous protein 2

Pathways from BioSystems

Homologies

	CHP2	XP_001095666.1
Bos taurus (cattle)	CHP2	NP_001179334.1
Pan troglodytes (chimpanzee)	CHP2	XP_523319.3
Mus musculus (house mouse)	Chp2	NP_081639.1
Caenorhabditis elegans (roundworm)	pbo-1	NP_497601.1
Homo sapiens (human)	CHP2	NP_071380.1
Danio rerio (zebrafish)	chp2	NP_956130.1
Rattus norvegicus (Norway rat)	Chp2	NP_877402.1

Gene Ontology
Bibliography

Related articles in PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger.
Pang T, Wakabayashi S, Shigekawa M
The Journal of biological chemistry277(46)43771-7(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Chp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04087	NM_027363.1 Latest version!	Mus musculus calcineurin-like EF hand protein 2 (Chp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu04087	XM_011241899.1 Latest version!	Mus musculus calcineurin-like EF hand protein 2 (Chp2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Chp2 ( NM_027363.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081639.1 Mus musculus calcineurin-like EF hand protein 2 (Chp2), mRNA.

Price & Availability↑

CloneID	OMu04087
Clone ID Related Accession (Same CDS sequence)	XM_011241899.1 , NM_027363.1
Accession Version	NM_027363.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 591bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	calcineurin B homologous protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC119204.1. On or before Sep 4, 2006 this sequence version replaced XM_355937.3, XM_991424.1, XM_923713.2, XM_982088.1, XM_982049.1, XM_982014.1. ##Evidence-Data-START## Transcript exon combination :: BC119202.1, AK008392.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTCAC GAAGCTCTCA TATCGCGCTC ATTCCAGACG TGGAGCACAT TCGCAGAGAG 
ACAGGCTTCT CGCAAGCCAG CCTGCTCCGC CTCTACCACC GGTTCCAAGC CCTGGACAGG 
GATGAAAAGG GCTTCCTAAG CCGCCTAGAC CTCCAGCAGA TCGGAGCACT GGCTGTGAAT 
CCACTGGGTG ACCGCATTAT AGACAGCTTC TTCCCCAACG GAAGTCAGAG ACTGTATTTC 
GCAGGCTTTG CCAGGGTCCT GGCTTATTTT CGACCTATAG ATGAAGAAGA TGCCACACTC 
CGAGACCCCA AGCAACCTGA ACCCCTAAAC AGCAGAATGA ACAAACTGCG CTTTGCATTT 
CAGCTCTATG ATCTGGATCG GGATGGGAAG ATCTCCAGGA ATGAAATGCT ACAGGTTCTC 
CGCCTCATGG TTGGGGTCCA GGTGACGGAT GAGCAGCTGG AGAGCATCAC AGACCGTACA 
GTGCAGGAAG CTGATGAGGA CGGGGATGGG GCTGTGTCCT TCCTGGAGTT CACCAAGTCC 
TTAGAGAAGA TGAACATCGA ACAAAAAATG AGCATCCGGA TCCTGAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081639.1
CDS	217..807
Translation	MGSRSSHIALIPDVEHIRRETGFSQASLLRLYHRFQALDRDEKGFLSRLDLQQIGALAVNPLGDRIIDSFFPNGSQRLYFAGFARVLAYFRPIDEEDATLRDPKQPEPLNSRMNKLRFAFQLYDLDRDGKISRNEMLQVLRLMVGVQVTDEQLESITDRTVQEADEDGDGAVSFLEFTKSLEKMNIEQKMSIRILK

Target ORF information:

RefSeq Version	NM_027363.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus calcineurin-like EF hand protein 2 (Chp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027363.1

ORF Insert Sequence:

ATGGGCTCAC GAAGCTCTCA TATCGCGCTC ATTCCAGACG TGGAGCACAT TCGCAGAGAG 
ACAGGCTTCT CGCAAGCCAG CCTGCTCCGC CTCTACCACC GGTTCCAAGC CCTGGACAGG 
GATGAAAAGG GCTTCCTAAG CCGCCTAGAC CTCCAGCAGA TCGGAGCACT GGCTGTGAAT 
CCACTGGGTG ACCGCATTAT AGACAGCTTC TTCCCCAACG GAAGTCAGAG ACTGTATTTC 
GCAGGCTTTG CCAGGGTCCT GGCTTATTTT CGACCTATAG ATGAAGAAGA TGCCACACTC 
CGAGACCCCA AGCAACCTGA ACCCCTAAAC AGCAGAATGA ACAAACTGCG CTTTGCATTT 
CAGCTCTATG ATCTGGATCG GGATGGGAAG ATCTCCAGGA ATGAAATGCT ACAGGTTCTC 
CGCCTCATGG TTGGGGTCCA GGTGACGGAT GAGCAGCTGG AGAGCATCAC AGACCGTACA 
GTGCAGGAAG CTGATGAGGA CGGGGATGGG GCTGTGTCCT TCCTGGAGTT CACCAAGTCC 
TTAGAGAAGA TGAACATCGA ACAAAAAATG AGCATCCGGA TCCTGAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Chp2 ( XM_011241899.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011240201.1 Mus musculus calcineurin-like EF hand protein 2 (Chp2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu04087
Clone ID Related Accession (Same CDS sequence)	XM_011241899.1 , NM_027363.1
Accession Version	XM_011241899.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 591bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	calcineurin B homologous protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTCAC GAAGCTCTCA TATCGCGCTC ATTCCAGACG TGGAGCACAT TCGCAGAGAG 
ACAGGCTTCT CGCAAGCCAG CCTGCTCCGC CTCTACCACC GGTTCCAAGC CCTGGACAGG 
GATGAAAAGG GCTTCCTAAG CCGCCTAGAC CTCCAGCAGA TCGGAGCACT GGCTGTGAAT 
CCACTGGGTG ACCGCATTAT AGACAGCTTC TTCCCCAACG GAAGTCAGAG ACTGTATTTC 
GCAGGCTTTG CCAGGGTCCT GGCTTATTTT CGACCTATAG ATGAAGAAGA TGCCACACTC 
CGAGACCCCA AGCAACCTGA ACCCCTAAAC AGCAGAATGA ACAAACTGCG CTTTGCATTT 
CAGCTCTATG ATCTGGATCG GGATGGGAAG ATCTCCAGGA ATGAAATGCT ACAGGTTCTC 
CGCCTCATGG TTGGGGTCCA GGTGACGGAT GAGCAGCTGG AGAGCATCAC AGACCGTACA 
GTGCAGGAAG CTGATGAGGA CGGGGATGGG GCTGTGTCCT TCCTGGAGTT CACCAAGTCC 
TTAGAGAAGA TGAACATCGA ACAAAAAATG AGCATCCGGA TCCTGAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011240201.1
CDS	323..913
Translation	MGSRSSHIALIPDVEHIRRETGFSQASLLRLYHRFQALDRDEKGFLSRLDLQQIGALAVNPLGDRIIDSFFPNGSQRLYFAGFARVLAYFRPIDEEDATLRDPKQPEPLNSRMNKLRFAFQLYDLDRDGKISRNEMLQVLRLMVGVQVTDEQLESITDRTVQEADEDGDGAVSFLEFTKSLEKMNIEQKMSIRILK

Target ORF information:

RefSeq Version	XM_011241899.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus calcineurin-like EF hand protein 2 (Chp2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241899.1

ORF Insert Sequence:

ATGGGCTCAC GAAGCTCTCA TATCGCGCTC ATTCCAGACG TGGAGCACAT TCGCAGAGAG 
ACAGGCTTCT CGCAAGCCAG CCTGCTCCGC CTCTACCACC GGTTCCAAGC CCTGGACAGG 
GATGAAAAGG GCTTCCTAAG CCGCCTAGAC CTCCAGCAGA TCGGAGCACT GGCTGTGAAT 
CCACTGGGTG ACCGCATTAT AGACAGCTTC TTCCCCAACG GAAGTCAGAG ACTGTATTTC 
GCAGGCTTTG CCAGGGTCCT GGCTTATTTT CGACCTATAG ATGAAGAAGA TGCCACACTC 
CGAGACCCCA AGCAACCTGA ACCCCTAAAC AGCAGAATGA ACAAACTGCG CTTTGCATTT 
CAGCTCTATG ATCTGGATCG GGATGGGAAG ATCTCCAGGA ATGAAATGCT ACAGGTTCTC 
CGCCTCATGG TTGGGGTCCA GGTGACGGAT GAGCAGCTGG AGAGCATCAC AGACCGTACA 
GTGCAGGAAG CTGATGAGGA CGGGGATGGG GCTGTGTCCT TCCTGGAGTT CACCAAGTCC 
TTAGAGAAGA TGAACATCGA ACAAAAAATG AGCATCCGGA TCCTGAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
PloS one12(7)e0180682(2017)
Sundberg JP,Dadras SS,Silva KA,Kennedy VE,Garland G,Murray SA,Sundberg BA,Schofield PN,Pratt CH

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger.
The Journal of biological chemistry277(46)43771-7(2002 Nov)
Pang T,Wakabayashi S,Shigekawa M