The following Mypn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mypn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu08266 | |
| Clone ID Related Accession (Same CDS sequence) | NM_182992.2 | |
| Accession Version | NM_182992.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3948bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-26 | |
| Organism | Mus musculus(house mouse) | |
| Product | myopalladin | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC155909.9. On or before Apr 9, 2009 this sequence version replaced XM_905765.2, XM_483911.3, NM_182992.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK220521.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGCAAGAAG ACAGCATAGA GGCATCCACT TCCATCTCTC AACTCCTGAG AGAAAGTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_892037.2 |
| CDS | 237..4184 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_182992.2 |
1 | ATGCAAGAAG ACAGCATAGA GGCATCCACT TCCATCTCTC AACTCCTGAG AGAAAGTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins. |
Biallelic Mutations in MYPN, Encoding Myopalladin, Are Associated with Childhood-Onset, Slowly Progressive Nemaline Myopathy. |
Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers. |
Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy. |
Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease. |
