Pnrc2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pnrc2
Entrez Gene ID	52830
Full Name	proline-rich nuclear receptor coactivator 2
Synonyms	0610011E17Rik,D4Bwg0593e
General protein information	Preferred Names proline-rich nuclear receptor coactivator 2 Names proline-rich nuclear receptor coactivator 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 D3\|4 68.01 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006539038.1	XP_006539101.1	proline-rich nuclear receptor coactivator 2 isoform X1
NM_026383.3	NP_080659.1	proline-rich nuclear receptor coactivator 2
XM_006539039.1	XP_006539102.1	proline-rich nuclear receptor coactivator 2 isoform X1

Pathways from BioSystems

Homologies

	LOC719213	XP_001113083.2
Pan troglodytes (chimpanzee)	PNRC2	NP_001238931.1
Bos taurus (cattle)	PNRC2	NP_001070425.1
Xenopus tropicalis (tropical clawed frog)	pnrc2	NP_001008433.1
Homo sapiens (human)	PNRC2	NP_060231.1
Mus musculus (house mouse)	Pnrc2	NP_080659.1
Gallus gallus (chicken)	PNRC2	NP_001006315.1
Rattus norvegicus (Norway rat)	Pnrc2	NP_001096830.1
Danio rerio (zebrafish)	pnrc2	NP_001123664.1

Gene Ontology
Bibliography

Related articles in PubMed

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S
Proceedings of the National Academy of Sciences of the United States of America110(6)E507-16(2013 Feb)

Staufen1-mediated mRNA decay functions in adipogenesis.
Cho H, Kim KM, Han S, Choe J, Park SG, Choi SS, Kim YK
Molecular cell46(4)495-506(2012 May)

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H
BMC genomics9511(2008 Oct)

Nuclear receptor coactivator PNRC2 regulates energy expenditure and adiposity.
Zhou D, Shen R, Ye JJ, Li Y, Tsark W, Isbell D, Tso P, Chen S
The Journal of biological chemistry283(1)541-53(2008 Jan)

eae36, a locus on mouse chromosome 4, controls susceptibility to experimental allergic encephalomyelitis in older mice and mice immunized in the winter.
Teuscher C, Doerge RW, Fillmore PD, Blankenhorn EP
Genetics172(2)1147-53(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study provides evidence that PNRC2 plays one or more important roles in controlling the energy balance between energy storage and energy expenditure. PNRC2 may be a new target in the treatment of obesity and related metabolic diseases.
Title: Nuclear receptor coactivator PNRC2 regulates energy expenditure and adiposity.

The finding that the PNRC2 promoter is activated by NFY and repressed by E2F1 indicates that in addition to functioning as nuclear receptor coactivator, PNRC2 may also play a role in the cell cycle.
Title: Transcriptional regulation of the mouse PNRC2 promoter by the nuclear factor Y (NFY) and E2F1.

The following Pnrc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pnrc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02145	NM_026383.3 Latest version!	Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu02145	XM_006539039.1 Latest version!	Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu02145	XM_006539038.1 Latest version!	Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pnrc2 ( NM_026383.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080659.1 Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), mRNA.

Price & Availability↑

CloneID	OMu02145
Clone ID Related Accession (Same CDS sequence)	XM_006539038.1 , NM_026383.3 , XM_006539039.1
Accession Version	NM_026383.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	proline-rich nuclear receptor coactivator 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672076.10, AK012073.1 and AK011192.1. On Jul 30, 2009 this sequence version replaced NM_026383.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK011192.1, AK013163.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386, SAMN00849389 [ECO:0000348] ##Evidence-Data-END##

ATGGGTGGCG GAGAGAGGTA TAACATTCCA GACCCTCAAT CTAGAAATGC TAGTAAGAAC 
CAAGAACAGC AAAATAGACA GAAGAGCAAG GATCAGAATT CTTCCCAGAC GAAGATTGCT 
CATAAGAAAA AGGAACGAGG ACATGGGTAC AATCCAGCAG CAGCAGCATG GCAGGCCATG 
CAAAATGGGG GAAAGACCAA GAGCCTTTCT AACAACTCCA ACTGGAATGC TGGTTTATCA 
AGTCCTAGCT TGCTTTTTAA GTCTCAAGCT AGTCAGAACT ATGCTGGAGC CAAATTTAGT 
GAACCACCAT CACCAAGTGT TCTCCCCAAG CCACCAAGCC ACTGGGTTCA TGTTTCCTTG 
AACCCTTCAG ATAAGGAAAC GATGACATTT CAACTTAAAA CCTTACTTAA GGTACAGGTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080659.1
CDS	397..819
Translation	MGGGERYNIPDPQSRNASKNQEQQNRQKSKDQNSSQTKIAHKKKERGHGYNPAAAAWQAMQNGGKTKSLSNNSNWNAGLSSPSLLFKSQASQNYAGAKFSEPPSPSVLPKPPSHWVHVSLNPSDKETMTFQLKTLLKVQV

Target ORF information:

RefSeq Version	NM_026383.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026383.3

ORF Insert Sequence:

ATGGGTGGCG GAGAGAGGTA TAACATTCCA GACCCTCAAT CTAGAAATGC TAGTAAGAAC 
CAAGAACAGC AAAATAGACA GAAGAGCAAG GATCAGAATT CTTCCCAGAC GAAGATTGCT 
CATAAGAAAA AGGAACGAGG ACATGGGTAC AATCCAGCAG CAGCAGCATG GCAGGCCATG 
CAAAATGGGG GAAAGACCAA GAGCCTTTCT AACAACTCCA ACTGGAATGC TGGTTTATCA 
AGTCCTAGCT TGCTTTTTAA GTCTCAAGCT AGTCAGAACT ATGCTGGAGC CAAATTTAGT 
GAACCACCAT CACCAAGTGT TCTCCCCAAG CCACCAAGCC ACTGGGTTCA TGTTTCCTTG 
AACCCTTCAG ATAAGGAAAC GATGACATTT CAACTTAAAA CCTTACTTAA GGTACAGGTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pnrc2 ( XM_006539038.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539101.1 Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu02145
Clone ID Related Accession (Same CDS sequence)	XM_006539038.1 , NM_026383.3 , XM_006539039.1
Accession Version	XM_006539038.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	proline-rich nuclear receptor coactivator 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTGGCG GAGAGAGGTA TAACATTCCA GACCCTCAAT CTAGAAATGC TAGTAAGAAC 
CAAGAACAGC AAAATAGACA GAAGAGCAAG GATCAGAATT CTTCCCAGAC GAAGATTGCT 
CATAAGAAAA AGGAACGAGG ACATGGGTAC AATCCAGCAG CAGCAGCATG GCAGGCCATG 
CAAAATGGGG GAAAGACCAA GAGCCTTTCT AACAACTCCA ACTGGAATGC TGGTTTATCA 
AGTCCTAGCT TGCTTTTTAA GTCTCAAGCT AGTCAGAACT ATGCTGGAGC CAAATTTAGT 
GAACCACCAT CACCAAGTGT TCTCCCCAAG CCACCAAGCC ACTGGGTTCA TGTTTCCTTG 
AACCCTTCAG ATAAGGAAAC GATGACATTT CAACTTAAAA CCTTACTTAA GGTACAGGTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539101.1
CDS	615..1037
Translation	MGGGERYNIPDPQSRNASKNQEQQNRQKSKDQNSSQTKIAHKKKERGHGYNPAAAAWQAMQNGGKTKSLSNNSNWNAGLSSPSLLFKSQASQNYAGAKFSEPPSPSVLPKPPSHWVHVSLNPSDKETMTFQLKTLLKVQV

Target ORF information:

RefSeq Version	XM_006539038.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539038.1

ORF Insert Sequence:

ATGGGTGGCG GAGAGAGGTA TAACATTCCA GACCCTCAAT CTAGAAATGC TAGTAAGAAC 
CAAGAACAGC AAAATAGACA GAAGAGCAAG GATCAGAATT CTTCCCAGAC GAAGATTGCT 
CATAAGAAAA AGGAACGAGG ACATGGGTAC AATCCAGCAG CAGCAGCATG GCAGGCCATG 
CAAAATGGGG GAAAGACCAA GAGCCTTTCT AACAACTCCA ACTGGAATGC TGGTTTATCA 
AGTCCTAGCT TGCTTTTTAA GTCTCAAGCT AGTCAGAACT ATGCTGGAGC CAAATTTAGT 
GAACCACCAT CACCAAGTGT TCTCCCCAAG CCACCAAGCC ACTGGGTTCA TGTTTCCTTG 
AACCCTTCAG ATAAGGAAAC GATGACATTT CAACTTAAAA CCTTACTTAA GGTACAGGTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pnrc2 ( XM_006539039.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006539102.1 Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu02145
Clone ID Related Accession (Same CDS sequence)	XM_006539038.1 , NM_026383.3 , XM_006539039.1
Accession Version	XM_006539039.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	proline-rich nuclear receptor coactivator 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTGGCG GAGAGAGGTA TAACATTCCA GACCCTCAAT CTAGAAATGC TAGTAAGAAC 
CAAGAACAGC AAAATAGACA GAAGAGCAAG GATCAGAATT CTTCCCAGAC GAAGATTGCT 
CATAAGAAAA AGGAACGAGG ACATGGGTAC AATCCAGCAG CAGCAGCATG GCAGGCCATG 
CAAAATGGGG GAAAGACCAA GAGCCTTTCT AACAACTCCA ACTGGAATGC TGGTTTATCA 
AGTCCTAGCT TGCTTTTTAA GTCTCAAGCT AGTCAGAACT ATGCTGGAGC CAAATTTAGT 
GAACCACCAT CACCAAGTGT TCTCCCCAAG CCACCAAGCC ACTGGGTTCA TGTTTCCTTG 
AACCCTTCAG ATAAGGAAAC GATGACATTT CAACTTAAAA CCTTACTTAA GGTACAGGTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006539102.1
CDS	628..1050
Translation	MGGGERYNIPDPQSRNASKNQEQQNRQKSKDQNSSQTKIAHKKKERGHGYNPAAAAWQAMQNGGKTKSLSNNSNWNAGLSSPSLLFKSQASQNYAGAKFSEPPSPSVLPKPPSHWVHVSLNPSDKETMTFQLKTLLKVQV

Target ORF information:

RefSeq Version	XM_006539039.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus proline-rich nuclear receptor coactivator 2 (Pnrc2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006539039.1

ORF Insert Sequence:

ATGGGTGGCG GAGAGAGGTA TAACATTCCA GACCCTCAAT CTAGAAATGC TAGTAAGAAC 
CAAGAACAGC AAAATAGACA GAAGAGCAAG GATCAGAATT CTTCCCAGAC GAAGATTGCT 
CATAAGAAAA AGGAACGAGG ACATGGGTAC AATCCAGCAG CAGCAGCATG GCAGGCCATG 
CAAAATGGGG GAAAGACCAA GAGCCTTTCT AACAACTCCA ACTGGAATGC TGGTTTATCA 
AGTCCTAGCT TGCTTTTTAA GTCTCAAGCT AGTCAGAACT ATGCTGGAGC CAAATTTAGT 
GAACCACCAT CACCAAGTGT TCTCCCCAAG CCACCAAGCC ACTGGGTTCA TGTTTCCTTG 
AACCCTTCAG ATAAGGAAAC GATGACATTT CAACTTAAAA CCTTACTTAA GGTACAGGTA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Proceedings of the National Academy of Sciences of the United States of America110(6)E507-16(2013 Feb)
Lumayag S,Haldin CE,Corbett NJ,Wahlin KJ,Cowan C,Turturro S,Larsen PE,Kovacs B,Witmer PD,Valle D,Zack DJ,Nicholson DA,Xu S

Staufen1-mediated mRNA decay functions in adipogenesis.
Molecular cell46(4)495-506(2012 May)
Cho H,Kim KM,Han S,Choe J,Park SG,Choi SS,Kim YK

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
BMC genomics9511(2008 Oct)
Tamplin OJ,Kinzel D,Cox BJ,Bell CE,Rossant J,Lickert H

Nuclear receptor coactivator PNRC2 regulates energy expenditure and adiposity.
The Journal of biological chemistry283(1)541-53(2008 Jan)
Zhou D,Shen R,Ye JJ,Li Y,Tsark W,Isbell D,Tso P,Chen S

eae36, a locus on mouse chromosome 4, controls susceptibility to experimental allergic encephalomyelitis in older mice and mice immunized in the winter.
Genetics172(2)1147-53(2006 Feb)
Teuscher C,Doerge RW,Fillmore PD,Blankenhorn EP