Slc22a20 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc22a20
Entrez Gene ID	381203
Full Name	solute carrier family 22 (organic anion transporter), member 20
Synonyms	Gm963,OAT1-L,mOAT6
General protein information	Preferred Names solute carrier family 22 (organic anion transporter), member 20 Names solute carrier family 22 member 20 OAT1-like organic anion transporter SLC22 organic anion transporter organic anion transporter 6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 A

mRNA and Protein(s)

mRNA	Protein	Name
NM_198650.2	NP_941052.1	solute carrier family 22 member 20

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC22A20	XP_001169267.2
Canis lupus familiaris (dog)	LOC612044	XP_854865.2
Bos taurus (cattle)	SLC22A20	XP_002699386.1
Mus musculus (house mouse)	Slc22a20	NP_941052.1
Xenopus tropicalis (tropical clawed frog)	LOC100489586	XP_004913725.1

Gene Ontology
Bibliography

Related articles in PubMed

Organic anion transporter 6 (Slc22a20) specificity and Sertoli cell-specific expression provide new insight on potential endogenous roles.
Schnabolk GW, Gupta B, Mulgaonkar A, Kulkarni M, Sweet DH
The Journal of pharmacology and experimental therapeutics334(3)927-35(2010 Sep)

Interaction of organic cations with organic anion transporters.
Ahn SY, Eraly SA, Tsigelny I, Nigam SK
The Journal of biological chemistry284(45)31422-30(2009 Nov)

Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination.
Truong DM, Kaler G, Khandelwal A, Swaan PW, Nigam SK
The Journal of biological chemistry283(13)8654-63(2008 Mar)

Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, Nigam SK
The Journal of biological chemistry282(33)23841-53(2007 Aug)

Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions.
Kaler G, Truong DM, Sweeney DE, Logan DW, Nagle M, Wu W, Eraly SA, Nigam SK
Biochemical and biophysical research communications351(4)872-6(2006 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

expression in Sertoli cells suggests Oat6 may be an important determinant of blood-testis barrier function
Title: Organic anion transporter 6 (Slc22a20) specificity and Sertoli cell-specific expression provide new insight on potential endogenous roles.

Oat1, Oat3, and Oat6 function largely in organic anion transport but also bind and transport organic cations.
Title: Interaction of organic cations with organic anion transporters.

despite sharing close overall sequence homology, Oat1, Oat3, and Oat6 have signficantly different binding pockets
Title: Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination.

the substrate binding preferences and transport function of olfactory organic anion transporter, Oat6, in comparison with the more broadly expressed transporter, Oat1
Title: Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.

Oat6 might play a direct or indirect role in olfaction, such as modulation of the availability of odorant organic anions at the mucosal surface.
Title: Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions.

The following Slc22a20 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc22a20 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09129	NM_198650.2 Latest version!	Mus musculus solute carrier family 22 (organic anion transporter), member 20 (Slc22a20), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$328.30 $469.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc22a20 ( NM_198650.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_941052.1 Mus musculus solute carrier family 22 (organic anion transporter), member 20 (Slc22a20), mRNA.

Price & Availability↑

CloneID	OMu09129
Clone ID Related Accession (Same CDS sequence)	NM_198650.2
Accession Version	NM_198650.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	solute carrier family 22 member 20
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC127271.3. On Nov 17, 2006 this sequence version replaced NM_198650.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC046588.1, AY194118.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849377, SAMN00849383 [ECO:0000350] ##Evidence-Data-END##

ATGGCCTTCA CAGACCTGCT GGATGCCCTG GGAGGCGTGG GTCGCTTCCA GCTTGTCTAT 
ACAGCCTTGC TGCTGCTGCC CTGTGGGCTG CTGGCTTGCC ATACCTTCCT ACAGAACTTC 
ACGGCTGCTG CACCCCCTCA CCACTGCCAA CATCCTGCCA ACTACACAGA ACCTACCACC 
AATGTCTCAG GGGTCTGGCT GAGGGCTGCC ATACCCCTGA ACCAGCATGG GGACCCCGAG 
CCGTGCCGGC GCTATGTAGA ACCTCAGTGG GCCCTTCTGA AACCCAACGC CTCCTCCCAT 
GGGGTGGCCA CCGAGGGCTG CAAGGATGGT TGGGTCTACG ACCGAAGCAT TTTCCCATCT 
ACCATTGTGA TGGAGTGGGA CCTGGTGTGT GAGGCCCGCA CCCTTCGTGA CCTGGCTCAG 
TCCATCTACA TGTCCGGGGT GTTGGTGGGA GCCGCCTTGT TTGGTGGTCT TGCTGACAGG 
TTGGGTCGCA AGGCCCCACT GGTGTGGTCG TACCTGCAGC TGGCAGTTTC GGGGGCTGCC 
ACAGCGTATG TGGGCTCCTT CAGTGCCTAC TGCGTCTTCC GCTTCCTGAT GGGCATGACC 
TTCTCCGGCA TCATCCTTAA CTCCCTCTCC CTGGTTGTAG AATGGATGCC AACCAGAGGC 
CGTACAGTAG CAGGCATCTT GTTGGGTTTC TCCTTCACCT TGGGCCAGCT CATCCTGGCT 
GGCGTGGCAT ACCTGATCCG GCCCTGGCGG TGGCTGCAGT TTGCTGTGTC TGCTCCTTTT 
CTGGTCTTTT TCCTCTATTC TTGGTGGCTT CCAGAGTCAT CCCGATGGCT CCTCCTTCAC 
GGCAAGGCCC AGCAAGCTGT GCAGAACCTT CAGAAGGTGG CCATGATGAA TGGCAGGAAG 
GCGGAAGGGG AGAGGCTGAC TACAGAGGTG GTGAGCTCCT ACATCCAGGA TGAGTTTGCA 
AGTGTCCGCA CCTCCAACTC CATCTTGGAC CTCTTTAGAA CCCCTGCCAT CAGAAGGGTC 
ACGTGCTGTC TCATGGGGGT CTGGTTCTCT AATTCTGTGG CTTACTACGG CCTGGCCATG 
GACCTGCAGA AGTTTGGGCT CAGCATCTAC CTGGTACAGG CTCTGTTTGG GATCATCGAT 
ATCCCGGCCA TGCTGGTCGC CACCACCACG ATGATTTATG TGGGACGACG GGCCACAGTG 
TCCTCCTTCC TCATACTAGC TGGGCTCATG GTCATTGCCA ACATGTTTAT GCCTGAGGAT 
CTGCAGACCT TGCGGACAGT GCAGGCAGCG CTGGGCAAAG GCTGCCTGGC CAGCTCCTTC 
ATCTGCGTGT ATCTGTTCAC GGGAGAACTC TATCCCACAG AGATCAGGCA GATGGGGATG 
GGATTTGCTT CTGTCAATGC CCGCCTCGGA GGCTTGGTGG CACCCCTGAT CACCACACTT 
GGCGAGATCA GTCCAGTTCT GCCACCTGTA TCCTTTGGTG CCACTTCAGT CTTGGCTGGA 
ATGGCTGTCG CCTGCTTCCT GACTGAGACC CGCAATGTGC CACTGGTAGA AACTATTGCT 
GCAATGGAGA GACGAGTCAA ACAAGGCCGT TCCAAAAGAG ACACAGAACA GAAGAGTGAA 
GAAATTTCTC TTCAGCAGCT GGGGGCTTCA CCCCTCAAAG AAACCATTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_941052.1
CDS	4..1674
Translation	MAFTDLLDALGGVGRFQLVYTALLLLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEPTTNVSGVWLRAAIPLNQHGDPEPCRRYVEPQWALLKPNASSHGVATEGCKDGWVYDRSIFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAATAYVGSFSAYCVFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERLTTEVVSSYIQDEFASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDIPAMLVATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGKGCLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAGMAVACFLTETRNVPLVETIAAMERRVKQGRSKRDTEQKSEEISLQQLGASPLKETI

Target ORF information:

RefSeq Version	NM_198650.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 22 (organic anion transporter), member 20 (Slc22a20), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198650.2

ORF Insert Sequence:

ATGGCCTTCA CAGACCTGCT GGATGCCCTG GGAGGCGTGG GTCGCTTCCA GCTTGTCTAT 
ACAGCCTTGC TGCTGCTGCC CTGTGGGCTG CTGGCTTGCC ATACCTTCCT ACAGAACTTC 
ACGGCTGCTG CACCCCCTCA CCACTGCCAA CATCCTGCCA ACTACACAGA ACCTACCACC 
AATGTCTCAG GGGTCTGGCT GAGGGCTGCC ATACCCCTGA ACCAGCATGG GGACCCCGAG 
CCGTGCCGGC GCTATGTAGA ACCTCAGTGG GCCCTTCTGA AACCCAACGC CTCCTCCCAT 
GGGGTGGCCA CCGAGGGCTG CAAGGATGGT TGGGTCTACG ACCGAAGCAT TTTCCCATCT 
ACCATTGTGA TGGAGTGGGA CCTGGTGTGT GAGGCCCGCA CCCTTCGTGA CCTGGCTCAG 
TCCATCTACA TGTCCGGGGT GTTGGTGGGA GCCGCCTTGT TTGGTGGTCT TGCTGACAGG 
TTGGGTCGCA AGGCCCCACT GGTGTGGTCG TACCTGCAGC TGGCAGTTTC GGGGGCTGCC 
ACAGCGTATG TGGGCTCCTT CAGTGCCTAC TGCGTCTTCC GCTTCCTGAT GGGCATGACC 
TTCTCCGGCA TCATCCTTAA CTCCCTCTCC CTGGTTGTAG AATGGATGCC AACCAGAGGC 
CGTACAGTAG CAGGCATCTT GTTGGGTTTC TCCTTCACCT TGGGCCAGCT CATCCTGGCT 
GGCGTGGCAT ACCTGATCCG GCCCTGGCGG TGGCTGCAGT TTGCTGTGTC TGCTCCTTTT 
CTGGTCTTTT TCCTCTATTC TTGGTGGCTT CCAGAGTCAT CCCGATGGCT CCTCCTTCAC 
GGCAAGGCCC AGCAAGCTGT GCAGAACCTT CAGAAGGTGG CCATGATGAA TGGCAGGAAG 
GCGGAAGGGG AGAGGCTGAC TACAGAGGTG GTGAGCTCCT ACATCCAGGA TGAGTTTGCA 
AGTGTCCGCA CCTCCAACTC CATCTTGGAC CTCTTTAGAA CCCCTGCCAT CAGAAGGGTC 
ACGTGCTGTC TCATGGGGGT CTGGTTCTCT AATTCTGTGG CTTACTACGG CCTGGCCATG 
GACCTGCAGA AGTTTGGGCT CAGCATCTAC CTGGTACAGG CTCTGTTTGG GATCATCGAT 
ATCCCGGCCA TGCTGGTCGC CACCACCACG ATGATTTATG TGGGACGACG GGCCACAGTG 
TCCTCCTTCC TCATACTAGC TGGGCTCATG GTCATTGCCA ACATGTTTAT GCCTGAGGAT 
CTGCAGACCT TGCGGACAGT GCAGGCAGCG CTGGGCAAAG GCTGCCTGGC CAGCTCCTTC 
ATCTGCGTGT ATCTGTTCAC GGGAGAACTC TATCCCACAG AGATCAGGCA GATGGGGATG 
GGATTTGCTT CTGTCAATGC CCGCCTCGGA GGCTTGGTGG CACCCCTGAT CACCACACTT 
GGCGAGATCA GTCCAGTTCT GCCACCTGTA TCCTTTGGTG CCACTTCAGT CTTGGCTGGA 
ATGGCTGTCG CCTGCTTCCT GACTGAGACC CGCAATGTGC CACTGGTAGA AACTATTGCT 
GCAATGGAGA GACGAGTCAA ACAAGGCCGT TCCAAAAGAG ACACAGAACA GAAGAGTGAA 
GAAATTTCTC TTCAGCAGCT GGGGGCTTCA CCCCTCAAAG AAACCATTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Organic anion transporter 6 (Slc22a20) specificity and Sertoli cell-specific expression provide new insight on potential endogenous roles.
The Journal of pharmacology and experimental therapeutics334(3)927-35(2010 Sep)
Schnabolk GW,Gupta B,Mulgaonkar A,Kulkarni M,Sweet DH

Interaction of organic cations with organic anion transporters.
The Journal of biological chemistry284(45)31422-30(2009 Nov)
Ahn SY,Eraly SA,Tsigelny I,Nigam SK

Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination.
The Journal of biological chemistry283(13)8654-63(2008 Mar)
Truong DM,Kaler G,Khandelwal A,Swaan PW,Nigam SK

Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
The Journal of biological chemistry282(33)23841-53(2007 Aug)
Kaler G,Truong DM,Khandelwal A,Nagle M,Eraly SA,Swaan PW,Nigam SK

Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions.
Biochemical and biophysical research communications351(4)872-6(2006 Dec)
Kaler G,Truong DM,Sweeney DE,Logan DW,Nagle M,Wu W,Eraly SA,Nigam SK