Scd4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scd4
Entrez Gene ID	329065
Full Name	stearoyl-coenzyme A desaturase 4
Synonyms	ACOD4
General protein information	Preferred Names stearoyl-coenzyme A desaturase 4 Names acyl-CoA desaturase 4 delta(9)-desaturase 4 fatty acid desaturase 4 stearoyl-CoA desaturase 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_183216.3	NP_899039.2	acyl-CoA desaturase 4

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Scd4	NP_899039.2
Rattus norvegicus (Norway rat)	Scd4	XP_574671.5
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004572	XP_313877.5

Gene Ontology
Bibliography

Related articles in PubMed

Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity.
Escobedo N, Contreras O, Mu?oz R, Far?as M, Carrasco H, Hill C, Tran U, Pryor SE, Wessely O, Copp AJ, Larra?n J
Development (Cambridge, England)140(14)3008-17(2013 Jul)

Identification of mouse palmitoyl-coenzyme A Delta9-desaturase.
Miyazaki M, Bruggink SM, Ntambi JM
Journal of lipid research47(4)700-4(2006 Apr)

Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors.
Miyazaki M, Jacobson MJ, Man WC, Cohen P, Asilmaz E, Friedman JM, Ntambi JM
The Journal of biological chemistry278(36)33904-11(2003 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show that mouse stearoyl-coenzyme A desaturase (SCD)1, 2, and 4 desaturate both C18:0 and C16:0, whereas mouse SCD3 uses C16:0 but not C18:0.
Title: Identification of mouse palmitoyl-coenzyme A Delta9-desaturase.

SCD4 demonstrates tissue-specific regulation by leptin and dietary factors.
Title: Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors.

The following Scd4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scd4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16082	NM_183216.3 Latest version!	Mus musculus stearoyl-coenzyme A desaturase 4 (Scd4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scd4 ( NM_183216.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_899039.2 Mus musculus stearoyl-coenzyme A desaturase 4 (Scd4), mRNA.

Price & Availability↑

CloneID	OMu16082
Clone ID Related Accession (Same CDS sequence)	NM_183216.3
Accession Version	NM_183216.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	acyl-CoA desaturase 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123853.2. On Nov 17, 2006 this sequence version replaced NM_183216.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AY430080.1, BC141234.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGACGGCCC ACTTGCCACA AGAGATCTCC AGCAGGTGTA GCACTACCAA CATCATGGAA 
CCCCACTCCC GGAGACAGCA GGATGGAGAA GAGAAGATGC CCCTCCAGGC AGAAGATATC 
CGGCCTGAAA TAAAAGATGA TCTGTATGAC CCCAGCTACC AGGATGAGGA GGGACCCCCG 
CCCAAGCTGG AGTACGTCTG GAGGAACATC ATCTTCATGG CCCTGCTGCA CGTGGGAGCC 
CTGTACGGGA TCACACTGGT TCCCTCCTGC AAGGTCTACA CCTGGCTCTT GGGAGTATTC 
TACAACGTGG TTGCCGGTTT GGGCATCACA GCCGGAGCGC ATCGCTTGTG GAGCCACCGA 
ACCTATAAAG CAAGGCTGCC CCTACGCATC TTCCTCATCA TGGCCAATAC CATGGCTTTC 
CAGAATGACG TGTATGAATG GGCCCGAGAT CACCGCGCCC ACCACAAGTT CTCAGAAACA 
CACGCCGACC CTCACAATTC CCGCCGTGGC TTCTTCTTCT CTCACGTGGG TTGGCTGCTT 
GTGCGCAAAC ATCCGGCTGT CAAAGAGAAG GGCAAAAACC TGGACATGTC TGACCTGAAA 
GCCGAGAAGC TGGTGATGTT CCAGAGGAGG TACTACAAGC TAGCTGTCAC GCTCATGTTC 
ATCATTCTGC CCACACTGGT ACCCTGGTAC TTGTGGGGTG AGACTTTTCA ACACAGCTTA 
TGCGTCTCGA ATTTCCTGCG GTATGCTGTG CTTCTAAACT TCACTTGGCT GGTGAACAGT 
GCGGCCCACC TCTACGGATA CCGGCCCTAT GACAGGGGCA TTGGTGCCCG GGAGAATCCC 
TTCGTTTCAA TGGCATCTTT AGGCGAGGGC TTCCACAACT ACCATCACAC GTTCCCCTAC 
GATTACTCTG TCAGTGAGTA CCGCTGGCAC ATCAACTTCA CCACGTTTTT CATCGACTGC 
ATGGCTGCCC TGGGCCTGGC TTACGACCGG AAGAAAGTAT CTAAGGCCGT TGTCTTAGCC 
AGGATTAAGA GAACTGGAGA TGGGAGTCAC AAGAGTAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_899039.2
CDS	167..1228
Translation	MTAHLPQEISSRCSTTNIMEPHSRRQQDGEEKMPLQAEDIRPEIKDDLYDPSYQDEEGPPPKLEYVWRNIIFMALLHVGALYGITLVPSCKVYTWLLGVFYNVVAGLGITAGAHRLWSHRTYKARLPLRIFLIMANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGKNLDMSDLKAEKLVMFQRRYYKLAVTLMFIILPTLVPWYLWGETFQHSLCVSNFLRYAVLLNFTWLVNSAAHLYGYRPYDRGIGARENPFVSMASLGEGFHNYHHTFPYDYSVSEYRWHINFTTFFIDCMAALGLAYDRKKVSKAVVLARIKRTGDGSHKSS

Target ORF information:

RefSeq Version	NM_183216.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus stearoyl-coenzyme A desaturase 4 (Scd4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183216.3

ORF Insert Sequence:

ATGACGGCCC ACTTGCCACA AGAGATCTCC AGCAGGTGTA GCACTACCAA CATCATGGAA 
CCCCACTCCC GGAGACAGCA GGATGGAGAA GAGAAGATGC CCCTCCAGGC AGAAGATATC 
CGGCCTGAAA TAAAAGATGA TCTGTATGAC CCCAGCTACC AGGATGAGGA GGGACCCCCG 
CCCAAGCTGG AGTACGTCTG GAGGAACATC ATCTTCATGG CCCTGCTGCA CGTGGGAGCC 
CTGTACGGGA TCACACTGGT TCCCTCCTGC AAGGTCTACA CCTGGCTCTT GGGAGTATTC 
TACAACGTGG TTGCCGGTTT GGGCATCACA GCCGGAGCGC ATCGCTTGTG GAGCCACCGA 
ACCTATAAAG CAAGGCTGCC CCTACGCATC TTCCTCATCA TGGCCAATAC CATGGCTTTC 
CAGAATGACG TGTATGAATG GGCCCGAGAT CACCGCGCCC ACCACAAGTT CTCAGAAACA 
CACGCCGACC CTCACAATTC CCGCCGTGGC TTCTTCTTCT CTCACGTGGG TTGGCTGCTT 
GTGCGCAAAC ATCCGGCTGT CAAAGAGAAG GGCAAAAACC TGGACATGTC TGACCTGAAA 
GCCGAGAAGC TGGTGATGTT CCAGAGGAGG TACTACAAGC TAGCTGTCAC GCTCATGTTC 
ATCATTCTGC CCACACTGGT ACCCTGGTAC TTGTGGGGTG AGACTTTTCA ACACAGCTTA 
TGCGTCTCGA ATTTCCTGCG GTATGCTGTG CTTCTAAACT TCACTTGGCT GGTGAACAGT 
GCGGCCCACC TCTACGGATA CCGGCCCTAT GACAGGGGCA TTGGTGCCCG GGAGAATCCC 
TTCGTTTCAA TGGCATCTTT AGGCGAGGGC TTCCACAACT ACCATCACAC GTTCCCCTAC 
GATTACTCTG TCAGTGAGTA CCGCTGGCAC ATCAACTTCA CCACGTTTTT CATCGACTGC 
ATGGCTGCCC TGGGCCTGGC TTACGACCGG AAGAAAGTAT CTAAGGCCGT TGTCTTAGCC 
AGGATTAAGA GAACTGGAGA TGGGAGTCAC AAGAGTAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity.
Development (Cambridge, England)140(14)3008-17(2013 Jul)
Escobedo N,Contreras O,Mu?oz R,Far?as M,Carrasco H,Hill C,Tran U,Pryor SE,Wessely O,Copp AJ,Larra?n J

Identification of mouse palmitoyl-coenzyme A Delta9-desaturase.
Journal of lipid research47(4)700-4(2006 Apr)
Miyazaki M,Bruggink SM,Ntambi JM

Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors.
The Journal of biological chemistry278(36)33904-11(2003 Sep)
Miyazaki M,Jacobson MJ,Man WC,Cohen P,Asilmaz E,Friedman JM,Ntambi JM