Vamp3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vamp3
Entrez Gene ID	22319
Full Name	vesicle-associated membrane protein 3
Synonyms	D130027G05Rik,VAMP-3,ceb
General protein information	Preferred Names vesicle-associated membrane protein 3 Names vesicle-associated membrane protein 3 cellubrevin synaptobrevin-3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_009498.4	NP_033524.1	vesicle-associated membrane protein 3

Pathways from BioSystems

Homologies

	VAMP3	XP_001095950.1
Danio rerio (zebrafish)	vamp3	NP_001002073.1
Gallus gallus (chicken)	VAMP3	NP_001034578.1
Homo sapiens (human)	VAMP3	NP_004772.1
Canis lupus familiaris (dog)	VAMP3	XP_005620536.1
Mus musculus (house mouse)	Vamp3	NP_033524.1
Bos taurus (cattle)	VAMP3	NP_001039380.1
Pan troglodytes (chimpanzee)	VAMP3	NP_001233512.1
Rattus norvegicus (Norway rat)	Vamp3	NP_476438.1
Xenopus tropicalis (tropical clawed frog)	vamp3	NP_001016972.1

Gene Ontology
Bibliography

Related articles in PubMed

Cellubrevin/vesicle-associated membrane protein-3-mediated endocytosis and trafficking regulate platelet functions.
Banerjee M, Joshi S, Zhang J, Moncman CL, Yadav S, Bouchard BA, Storrie B, Whiteheart SW
Blood130(26)2872-2883(2017 12)

VAMP3 and SNAP23 mediate the disturbed flow-induced endothelial microRNA secretion and smooth muscle hyperplasia.
Zhu JJ, Liu YF, Zhang YP, Zhao CR, Yao WJ, Li YS, Wang KC, Huang TS, Pang W, Wang XF, Wang X, Chien S, Zhou J
Proceedings of the National Academy of Sciences of the United States of America114(31)8271-8276(2017 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

VAMP3 is required for normal NKCC2 expression, renal function, and blood pressure.
Title: Vesicle-associated Membrane Protein 3 (VAMP3) Mediates Constitutive Trafficking of the Renal Co-transporter NKCC2 in Thick Ascending Limbs: ROLE IN RENAL FUNCTION AND BLOOD PRESSURE.

The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse.
Title: The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse.

Protein kinase D activates GLUT4 translocation via a VAMP3-dependent trafficking step.
Title: Overexpression of vesicle-associated membrane protein (VAMP) 3, but not VAMP2, protects glucose transporter (GLUT) 4 protein translocation in an in vitro model of cardiac insulin resistance.

Although a slight decrease in the rate of recovery of surviving bacteria was observed between 12 h and 36 h post-infection with Brucella melitensis, this was not significant indicating that VAMP3 is not involved in Brucella survival.
Title: Silencing of VAMP3 expression does not affect Brucella melitensis infection in mouse macrophages.

This important SNARE complex facilitates macrophage adhesion, spreading, and persistent macrophage migration on fibronectin through the delivery of VAMP3-positive membrane with its cargo to expand the plasma membrane.
Title: VAMP3 regulates podosome organisation in macrophages and together with Stx4/SNAP23 mediates adhesion, cell spreading and persistent migration.

The following Vamp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vamp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04290	NM_009498.4 Latest version!	Mus musculus vesicle-associated membrane protein 3 (Vamp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vamp3 ( NM_009498.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033524.1 Mus musculus vesicle-associated membrane protein 3 (Vamp3), mRNA.

Price & Availability↑

CloneID	OMu04290
Clone ID Related Accession (Same CDS sequence)	NM_009498.4
Accession Version	NM_009498.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Mus musculus(house mouse)
Product	vesicle-associated membrane protein 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK051272.1. On Apr 6, 2007 this sequence version replaced NM_009498.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK051272.1, SRR1660815.121912.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGTCTACAG GTGTGCCTTC GGGGTCAAGT GCTGCCACTG GCAGTAATCG AAGACTCCAG 
CAGACACAAA ATCAAGTAGA TGAGGTGGTT GACATCATGA GAGTCAATGT GGATAAGGTG 
TTAGAAAGAG ACCAGAAGCT CTCGGAGCTA GATGACCGCG CAGATGCACT GCAGGCAGGT 
GCCTCGCAGT TTGAAACAAG TGCTGCCAAG TTGAAGAGAA AGTATTGGTG GAAGAACTGC 
AAGATGTGGG CGATAGGGAT CAGTGTCCTG GTGATCATTG TCATCATCAT CATCGTGTGG 
TGTGTCTCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033524.1
CDS	79..390
Translation	MSTGVPSGSSAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGISVLVIIVIIIIVWCVS

Target ORF information:

RefSeq Version	NM_009498.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus vesicle-associated membrane protein 3 (Vamp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009498.4

ORF Insert Sequence:

ATGTCTACAG GTGTGCCTTC GGGGTCAAGT GCTGCCACTG GCAGTAATCG AAGACTCCAG 
CAGACACAAA ATCAAGTAGA TGAGGTGGTT GACATCATGA GAGTCAATGT GGATAAGGTG 
TTAGAAAGAG ACCAGAAGCT CTCGGAGCTA GATGACCGCG CAGATGCACT GCAGGCAGGT 
GCCTCGCAGT TTGAAACAAG TGCTGCCAAG TTGAAGAGAA AGTATTGGTG GAAGAACTGC 
AAGATGTGGG CGATAGGGAT CAGTGTCCTG GTGATCATTG TCATCATCAT CATCGTGTGG 
TGTGTCTCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cellubrevin/vesicle-associated membrane protein-3-mediated endocytosis and trafficking regulate platelet functions.
Blood130(26)2872-2883(2017 12)
Banerjee M,Joshi S,Zhang J,Moncman CL,Yadav S,Bouchard BA,Storrie B,Whiteheart SW

VAMP3 and SNAP23 mediate the disturbed flow-induced endothelial microRNA secretion and smooth muscle hyperplasia.
Proceedings of the National Academy of Sciences of the United States of America114(31)8271-8276(2017 Aug)
Zhu JJ,Liu YF,Zhang YP,Zhao CR,Yao WJ,Li YS,Wang KC,Huang TS,Pang W,Wang XF,Wang X,Chien S,Zhou J

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Vamp3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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