Mageb18 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mageb18
Entrez Gene ID	215641
Full Name	melanoma antigen family B, 18
Synonyms	B430216B18Rik
General protein information	Preferred Names melanoma antigen family B, 18 Names melanoma-associated antigen B18 MAGE-B18 antigen
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X\|X C2-C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_173783.3	NP_776144.1	melanoma-associated antigen B18

Pathways from BioSystems

Homologies

	MAGEB18	XP_001092141.1
Homo sapiens (human)	MAGEB18	NP_775970.1
Pan troglodytes (chimpanzee)	MAGEB18	XP_528911.1
Canis lupus familiaris (dog)	MAGEB18	XP_005641273.1
Mus musculus (house mouse)	Mageb18	NP_776144.1
Rattus norvegicus (Norway rat)	Mageb18	NP_001037711.1
Bos taurus (cattle)	MAGEB18	XP_005228419.1

Gene Ontology
Bibliography

Related articles in PubMed

The mouse Mageb18 gene encodes a ubiquitously expressed type?I MAGE protein and regulates cell proliferation and apoptosis in melanoma B16-F0 cells.
Lin Y, Wen T, Meng X, Wu Z, Zhao L, Wang P, Hong Z, Yin Z
The Biochemical journal443(3)779-88(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

demonstrate that knockdown of MAGEB18 inhibits the growth of B16-F0 cells and induces apoptosis, which correlates with increased levels of TP53 (tumour protein 53), p21, Bax and caspase 3
Title: The mouse Mageb18 gene encodes a ubiquitously expressed type?I MAGE protein and regulates cell proliferation and apoptosis in melanoma B16-F0 cells.

The following Mageb18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mageb18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04539	NM_173783.3 Latest version!	Mus musculus melanoma antigen family B, 18 (Mageb18), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mageb18 ( NM_173783.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_776144.1 Mus musculus melanoma antigen family B, 18 (Mageb18), mRNA.

Price & Availability↑

CloneID	OMu04539
Clone ID Related Accession (Same CDS sequence)	NM_173783.3
Accession Version	NM_173783.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-19
Organism	Mus musculus(house mouse)
Product	melanoma-associated antigen B18
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK046641.1. On Apr 6, 2007 this sequence version replaced NM_173783.2. ##Evidence-Data-START## Transcript exon combination :: AK046641.1, BB645562.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849381 [ECO:0000350] ##Evidence-Data-END##

ATGCCCCGTG GCCAGAAAAG CAAACTCCGT GCCCGTGAGA AGCGCCGCCA GGCCCGTGCT 
AAAAATGCAC AGGAGAAAGA AGCCTCTCCA GGTCCTTTCT ATGGGTGTCC ACATCAGGCT 
AGTCCTGTTG CCAGTATGCC TACATCTCCC AACATGCCAA TGGGAGAGCA GTCTACCTTT 
TCACACTCAT ATACAAGTAC AAGTGACCAA AACCTAGATG AGAAAAGTTC AGATGACTCT 
GAGGACACTG AGGACTGGTG TAAAGATCCT ATTAACCACA AAGTAGTTTT ACTGGTGCAG 
TTCCTGATGG AGAAGTATCA AAAGAAAGAG GTTATTACTA AGGCAGATAT GCTGAAGTAT 
GTTATCAAAA CATCTAAAAA CCACTTCAAT GAGATCCTAA AGAGAGCCTC AGAGCACATG 
GAACTGGCAT TTGGTATTGA TCTGAAGGAA GTTGATCCAA ACAGGCACTG CTATGCCCTT 
TTTAATAAAC TAGAACATAC TTTTGATGGA GTGATGGGTG AAGAAAAAAT GCCCAGTAGT 
GGCCTCCTAA TGATTGTGCT GGGTGTGATA TTCATGAATG ATAACTGTGT CTCTGAAACT 
GAGATCTGGA ATGTGCTGAG TATGATGGGT GTATATGCTA ATAGAAAACA CTTCATCTAT 
GGAGATCCTA AGAAGGTCAT CACTGAAGAT ATGGTGCAGC TAAAGTACTT GGAGTACCAA 
CAAGTGCCCA ACAGCAATCC TCCATCCTTT GAATTCACGT GGGGTCCAAG AGCCTGTGCT 
GAAATCAGCA AGATGAAAAT CTTGGAGTTT TGGGCCAAGA TCCATGATAC TACACCAGAT 
TCCTTCCCAA CCTTGTATGA AGCAGCTCTG AAAGATGAAG AAGAGAGAGC CCAAGCCAGG 
GCTGTAGCCA GGGCTCACAC TGCTGCAATG GCCAGTCCAT ATTCAAGAGC CACGGTGTGC 
AGCTCCTCCC ATACTAATAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776144.1
CDS	405..1388
Translation	MPRGQKSKLRAREKRRQARAKNAQEKEASPGPFYGCPHQASPVASMPTSPNMPMGEQSTFSHSYTSTSDQNLDEKSSDDSEDTEDWCKDPINHKVVLLVQFLMEKYQKKEVITKADMLKYVIKTSKNHFNEILKRASEHMELAFGIDLKEVDPNRHCYALFNKLEHTFDGVMGEEKMPSSGLLMIVLGVIFMNDNCVSETEIWNVLSMMGVYANRKHFIYGDPKKVITEDMVQLKYLEYQQVPNSNPPSFEFTWGPRACAEISKMKILEFWAKIHDTTPDSFPTLYEAALKDEEERAQARAVARAHTAAMASPYSRATVCSSSHTNI

Target ORF information:

RefSeq Version	NM_173783.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus melanoma antigen family B, 18 (Mageb18), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173783.3

ORF Insert Sequence:

ATGCCCCGTG GCCAGAAAAG CAAACTCCGT GCCCGTGAGA AGCGCCGCCA GGCCCGTGCT 
AAAAATGCAC AGGAGAAAGA AGCCTCTCCA GGTCCTTTCT ATGGGTGTCC ACATCAGGCT 
AGTCCTGTTG CCAGTATGCC TACATCTCCC AACATGCCAA TGGGAGAGCA GTCTACCTTT 
TCACACTCAT ATACAAGTAC AAGTGACCAA AACCTAGATG AGAAAAGTTC AGATGACTCT 
GAGGACACTG AGGACTGGTG TAAAGATCCT ATTAACCACA AAGTAGTTTT ACTGGTGCAG 
TTCCTGATGG AGAAGTATCA AAAGAAAGAG GTTATTACTA AGGCAGATAT GCTGAAGTAT 
GTTATCAAAA CATCTAAAAA CCACTTCAAT GAGATCCTAA AGAGAGCCTC AGAGCACATG 
GAACTGGCAT TTGGTATTGA TCTGAAGGAA GTTGATCCAA ACAGGCACTG CTATGCCCTT 
TTTAATAAAC TAGAACATAC TTTTGATGGA GTGATGGGTG AAGAAAAAAT GCCCAGTAGT 
GGCCTCCTAA TGATTGTGCT GGGTGTGATA TTCATGAATG ATAACTGTGT CTCTGAAACT 
GAGATCTGGA ATGTGCTGAG TATGATGGGT GTATATGCTA ATAGAAAACA CTTCATCTAT 
GGAGATCCTA AGAAGGTCAT CACTGAAGAT ATGGTGCAGC TAAAGTACTT GGAGTACCAA 
CAAGTGCCCA ACAGCAATCC TCCATCCTTT GAATTCACGT GGGGTCCAAG AGCCTGTGCT 
GAAATCAGCA AGATGAAAAT CTTGGAGTTT TGGGCCAAGA TCCATGATAC TACACCAGAT 
TCCTTCCCAA CCTTGTATGA AGCAGCTCTG AAAGATGAAG AAGAGAGAGC CCAAGCCAGG 
GCTGTAGCCA GGGCTCACAC TGCTGCAATG GCCAGTCCAT ATTCAAGAGC CACGGTGTGC 
AGCTCCTCCC ATACTAATAT CTAA