Pabpc2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pabpc2
Entrez Gene ID	18459
Full Name	poly(A) binding protein, cytoplasmic 2
Synonyms	Pabp,Pabp+,Pabp2
General protein information	Preferred Names poly(A) binding protein, cytoplasmic 2 Names poly A binding protein, cytoplasmic 2 poly A binding protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_011033.2	NP_035163.1	poly A binding protein, cytoplasmic 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pabpc2	NP_035163.1
Rattus norvegicus (Norway rat)	Pabpc2	NP_001099621.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.
Kashiwabara S, Tsuruta S, Okada K, Saegusa A, Miyagaki Y, Baba T
The Journal of reproduction and development62(3)305-10(2016 Jun)

Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.
Kimura M, Ishida K, Kashiwabara S, Baba T
Biology of reproduction80(3)545-54(2009 Mar)

Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.
Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H
The Journal of cell biology181(4)639-53(2008 May)

Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.
de Melo Neto OP, Walker JA, Martins de Sa CM, Standart N
Nucleic acids research28(17)3346-53(2000 Sep)

The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.
Kleene KC, Mastrangelo MA
Genomics61(2)194-200(1999 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

analysis of functional compensation for the loss of mouse PABPC2 in spermatogenic cells
Title: Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.

PABPC2 was present in pachytene spermatocytes and round spermatids, whereas elongating spermatids still included PABPC1.
Title: Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.

Poly(A) binding protein (PABP) is identified as an Msi1-binding protein, and Msi1 competes with eIF4G for PABP binding.
Title: Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.

The following Pabpc2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pabpc2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu24015	NM_011033.2 Latest version!	Mus musculus poly(A) binding protein, cytoplasmic 2 (Pabpc2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pabpc2 ( NM_011033.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035163.1 Mus musculus poly(A) binding protein, cytoplasmic 2 (Pabpc2), mRNA.

Price & Availability↑

CloneID	OMu24015
Clone ID Related Accession (Same CDS sequence)	NM_011033.2
Accession Version	NM_011033.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1887bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-26
Organism	Mus musculus(house mouse)
Product	poly A binding protein, cytoplasmic 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK077154.1, BC051134.1, CN837699.1 and AV259277.1. On or before May 4, 2006 this sequence version replaced XM_988736.1, NM_011033.1. COMPLETENESS: complete on the 3' end.

ATGAACTCCA GCGACCCAGG CTGTCCCATG GCCTCGCTCT ATGTGGGGGA CCTGCACCCT 
GATGTGACTG AGGCGATGCT CTATGAGAAG TTCAGCTCTG CCGGGCCCAT CCTTTCCATC 
CGGGTATACA GGGACGTGAT CACACGCCGT TCCCTGGGCT ATGCTTCCGT GAACTTTGAG 
CAGCCTGCTG ATGCAGAGCG AGCTTTGGAC ACCATGAATT TTGATGTCAT CAAGGGCAAG 
CCGGTCCGCA TCATGTGGTC TCAGCGTGAT CCATCACTTC GCAGGAGTGG AGTAGGCAAT 
GTGTTCATTA AAAATTTGAA CAAGACCATT GATAATAAAG CACTGTATGA TACATTCTCT 
GCTTTTGGCA ATATCCTTTC CTGCAAGGTG GTTAGCGATG AGAATGGCTC CAAGGGCCAC 
GGATTTGTAC ATTTTGAGAC AGAGGAGGCA GCAGAAAGAG CCATCGAGAA AATGAACGGG 
ATGCTTCTGA ATGACCGCAA AGTGTTTGTT GGACGGTTTA AGTCTCAGAA AGAACGAGAA 
GCCGAGCTTG GAACGGGGAC CAAGGAGTTT ACCAACGTTT ACATCAAGAA CTTTGGGGAC 
CGCATGGATG ACGAGACCCT GAATGGCCTC TTTGGCAGGT TTGGACAGAT CTTAAGTGTG 
AAAGTCATGA CCGATGAAGG TGGGAAATCG AAAGGATTCG GGTTCGTCAG CTTTGAAAGG 
CATGAAGATG CGCAGAAAGC GGTGGACGAG ATGAATGGTA AAGAACTCAA TGGAAAACAC 
ATTTATGTTG GTCGAGCGCA GAAAAAAGAT GACCGTCACA CAGAACTTAA ACACAAATTT 
GAACAGGTGA CACAAGATAA GAGCATCAGA TATCAGGGCA TTAACCTTTA TGTGAAAAAT 
CTTGATGATG GCATTGATGA TGAACGGCTC CAGAAAGAAT TTTCTCCATT TGGAACAATC 
ACCAGTACAA AGGTTATGAC AGAGGGTGGT CGCAGTAAAG GATTCGGTTT TGTGTGTTTC 
TCCTCCCCGG AAGAAGCCAC AAAAGCTGTT TCAGAAATGA ATGGGAGAAT TGTGGCCACG 
AAACCACTTT ATGTAGCTTT AGCCCAGCGC AAAGAAGAAC GTCAGGCTCA CCTCACTAAC 
CAATATATTC AAAGAATGGC AAGTGTACGA TCTGGGCCGA ACCCTGTTAA CCCCTACCAA 
CCAGCATCTT CCAGTTACTC TGTGGCCGCT GTCCCACAGA CTCAGAACTG CGTTCCATGC 
TGCCCTAGCC AAATTGCTCA ACCAAGGCCA AGTGCTCGCT GGATTGCTCA GGGTTCCCGG 
CCTCATCCAT TCCCCAATGT GCCTGGTGCT ATCCACCCAG CTGCTCCTAG ATCGTCGTTG 
ACTACTGTAA GACCAAGCTC TTCACACGTT CAAGTCACGA CAGCACATCG CATTACTAAC 
ACATCAGCAC AGATAACAGG TCAGCGTCCT GCCCCAGCCT CTTCAGCTAC AGCGACTCCT 
GTTCACTCGA TTCCACAGTA CAAGTATGCT GCAGGAGTCC AGAACTCCCA GCAACATCTT 
AATGCCCAGC TGGCGCAACA GCCCGCTGTT TGCATACAGG GTCAGGAACC TTGGACTGCT 
TCCATGTTAG TAACCGCTCC TCAAGAGCCG AAGCAAATGC TGGGTGAAAG GCTATTCCCT 
CTCATCCAAG CCATGCACCC GACTCTGGCT GGTAAGATCA CGGGCATGTT GCTGGACATT 
GATAACTCGG AACCACTTCG TATGCTTGAA TCTCCAGTGT CTCGGTGTTC TAGGGCTGAG 
GAAGCCGTGG CCACACTCCA AGCCCACCAA GTTAAAGAGG CTGCCCAGAA AGCTGTTGGC 
AGTACCTCTG GTGTCCCAAC TGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035163.1
CDS	188..2074
Translation	MNSSDPGCPMASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRRSGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMNGMLLNDRKVFVGRFKSQKEREAELGTGTKEFTNVYIKNFGDRMDDETLNGLFGRFGQILSVKVMTDEGGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKHIYVGRAQKKDDRHTELKHKFEQVTQDKSIRYQGINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVSEMNGRIVATKPLYVALAQRKEERQAHLTNQYIQRMASVRSGPNPVNPYQPASSSYSVAAVPQTQNCVPCCPSQIAQPRPSARWIAQGSRPHPFPNVPGAIHPAAPRSSLTTVRPSSSHVQVTTAHRITNTSAQITGQRPAPASSATATPVHSIPQYKYAAGVQNSQQHLNAQLAQQPAVCIQGQEPWTASMLVTAPQEPKQMLGERLFPLIQAMHPTLAGKITGMLLDIDNSEPLRMLESPVSRCSRAEEAVATLQAHQVKEAAQKAVGSTSGVPTV

Target ORF information:

RefSeq Version	NM_011033.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus poly(A) binding protein, cytoplasmic 2 (Pabpc2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011033.2

ORF Insert Sequence:

ATGAACTCCA GCGACCCAGG CTGTCCCATG GCCTCGCTCT ATGTGGGGGA CCTGCACCCT 
GATGTGACTG AGGCGATGCT CTATGAGAAG TTCAGCTCTG CCGGGCCCAT CCTTTCCATC 
CGGGTATACA GGGACGTGAT CACACGCCGT TCCCTGGGCT ATGCTTCCGT GAACTTTGAG 
CAGCCTGCTG ATGCAGAGCG AGCTTTGGAC ACCATGAATT TTGATGTCAT CAAGGGCAAG 
CCGGTCCGCA TCATGTGGTC TCAGCGTGAT CCATCACTTC GCAGGAGTGG AGTAGGCAAT 
GTGTTCATTA AAAATTTGAA CAAGACCATT GATAATAAAG CACTGTATGA TACATTCTCT 
GCTTTTGGCA ATATCCTTTC CTGCAAGGTG GTTAGCGATG AGAATGGCTC CAAGGGCCAC 
GGATTTGTAC ATTTTGAGAC AGAGGAGGCA GCAGAAAGAG CCATCGAGAA AATGAACGGG 
ATGCTTCTGA ATGACCGCAA AGTGTTTGTT GGACGGTTTA AGTCTCAGAA AGAACGAGAA 
GCCGAGCTTG GAACGGGGAC CAAGGAGTTT ACCAACGTTT ACATCAAGAA CTTTGGGGAC 
CGCATGGATG ACGAGACCCT GAATGGCCTC TTTGGCAGGT TTGGACAGAT CTTAAGTGTG 
AAAGTCATGA CCGATGAAGG TGGGAAATCG AAAGGATTCG GGTTCGTCAG CTTTGAAAGG 
CATGAAGATG CGCAGAAAGC GGTGGACGAG ATGAATGGTA AAGAACTCAA TGGAAAACAC 
ATTTATGTTG GTCGAGCGCA GAAAAAAGAT GACCGTCACA CAGAACTTAA ACACAAATTT 
GAACAGGTGA CACAAGATAA GAGCATCAGA TATCAGGGCA TTAACCTTTA TGTGAAAAAT 
CTTGATGATG GCATTGATGA TGAACGGCTC CAGAAAGAAT TTTCTCCATT TGGAACAATC 
ACCAGTACAA AGGTTATGAC AGAGGGTGGT CGCAGTAAAG GATTCGGTTT TGTGTGTTTC 
TCCTCCCCGG AAGAAGCCAC AAAAGCTGTT TCAGAAATGA ATGGGAGAAT TGTGGCCACG 
AAACCACTTT ATGTAGCTTT AGCCCAGCGC AAAGAAGAAC GTCAGGCTCA CCTCACTAAC 
CAATATATTC AAAGAATGGC AAGTGTACGA TCTGGGCCGA ACCCTGTTAA CCCCTACCAA 
CCAGCATCTT CCAGTTACTC TGTGGCCGCT GTCCCACAGA CTCAGAACTG CGTTCCATGC 
TGCCCTAGCC AAATTGCTCA ACCAAGGCCA AGTGCTCGCT GGATTGCTCA GGGTTCCCGG 
CCTCATCCAT TCCCCAATGT GCCTGGTGCT ATCCACCCAG CTGCTCCTAG ATCGTCGTTG 
ACTACTGTAA GACCAAGCTC TTCACACGTT CAAGTCACGA CAGCACATCG CATTACTAAC 
ACATCAGCAC AGATAACAGG TCAGCGTCCT GCCCCAGCCT CTTCAGCTAC AGCGACTCCT 
GTTCACTCGA TTCCACAGTA CAAGTATGCT GCAGGAGTCC AGAACTCCCA GCAACATCTT 
AATGCCCAGC TGGCGCAACA GCCCGCTGTT TGCATACAGG GTCAGGAACC TTGGACTGCT 
TCCATGTTAG TAACCGCTCC TCAAGAGCCG AAGCAAATGC TGGGTGAAAG GCTATTCCCT 
CTCATCCAAG CCATGCACCC GACTCTGGCT GGTAAGATCA CGGGCATGTT GCTGGACATT 
GATAACTCGG AACCACTTCG TATGCTTGAA TCTCCAGTGT CTCGGTGTTC TAGGGCTGAG 
GAAGCCGTGG CCACACTCCA AGCCCACCAA GTTAAAGAGG CTGCCCAGAA AGCTGTTGGC 
AGTACCTCTG GTGTCCCAAC TGTTTAA