Krtap8-1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Krtap8-1
Entrez Gene ID	16703
Full Name	keratin associated protein 8-1
Synonyms	AI326176
General protein information	Preferred Names keratin associated protein 8-1 Names keratin-associated protein 8-1 HGT keratin HGTp type I F HGTpI F high-glycine/tyrosine protein keratin keratin-associated protein 8.1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 C3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_010675.1	NP_034805.1	keratin-associated protein 8-1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.
Wu DD, Irwin DM, Zhang YP
BMC evolutionary biology8241(2008 Aug)

Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment.
Habtezion A, Toivola DM, Butcher EC, Omary MB
Journal of cell science118(Pt 9)1971-80(2005 May)

Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13.
Pruett ND, Tkatchenko TV, Jave-Suarez L, Jacobs DF, Potter CS, Tkatchenko AV, Schweizer J, Awgulewitsch A
The Journal of biological chemistry279(49)51524-33(2004 Dec)

Isolation and characterization of mouse high-glycine/tyrosine proteins.
Aoki N, Ito K, Ito M
The Journal of biological chemistry272(48)30512-8(1997 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Keratin-8 has a role in development of chronic spontaneous Th2 colitis
Title: Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment.

Krtap16 is a hair keratin-associated protein gene complex regulated by Hoxc13; localized to chromosome 16
Title: Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13.

The following Krtap8-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Krtap8-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58516	NM_010675.1 Latest version!	Mus musculus keratin associated protein 8-1 (Krtap8-1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Krtap8-1 ( NM_010675.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034805.1 Mus musculus keratin associated protein 8-1 (Krtap8-1), mRNA.

Price & Availability↑

CloneID	OMu58516
Clone ID Related Accession (Same CDS sequence)	NM_010675.1
Accession Version	NM_010675.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 186bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	keratin-associated protein 8-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK133727.1 and AC140433.3. On Jul 23, 2009 this sequence version replaced XM_917709.3.

ATGTACTACA CCGGCGCTGA GGGCTCTGTC TTCCCAGGAT GCTACTGGGG CAGCTATGGC 
TACCCTCTGG GGTACAGTGT TGGCTGTGGC TATGGTAGCA CCTACTCTCC AGTTGGCTAT 
GGCCTTGGCT ATGGCTACAA TGGCTGCGGG GCTTACAGAA GATACTGGCC ATTTGCTCTC 
TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034805.1
CDS	46..231
Translation	MYYTGAEGSVFPGCYWGSYGYPLGYSVGCGYGSTYSPVGYGLGYGYNGCGAYRRYWPFALY

Target ORF information:

RefSeq Version	NM_010675.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus keratin associated protein 8-1 (Krtap8-1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010675.1

ORF Insert Sequence:

ATGTACTACA CCGGCGCTGA GGGCTCTGTC TTCCCAGGAT GCTACTGGGG CAGCTATGGC 
TACCCTCTGG GGTACAGTGT TGGCTGTGGC TATGGTAGCA CCTACTCTCC AGTTGGCTAT 
GGCCTTGGCT ATGGCTACAA TGGCTGCGGG GCTTACAGAA GATACTGGCC ATTTGCTCTC 
TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.
BMC evolutionary biology8241(2008 Aug)
Wu DD,Irwin DM,Zhang YP

Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment.
Journal of cell science118(Pt 9)1971-80(2005 May)
Habtezion A,Toivola DM,Butcher EC,Omary MB

Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13.
The Journal of biological chemistry279(49)51524-33(2004 Dec)
Pruett ND,Tkatchenko TV,Jave-Suarez L,Jacobs DF,Potter CS,Tkatchenko AV,Schweizer J,Awgulewitsch A

Isolation and characterization of mouse high-glycine/tyrosine proteins.
The Journal of biological chemistry272(48)30512-8(1997 Nov)
Aoki N,Ito K,Ito M