Bex2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bex2
Entrez Gene ID	12069
Full Name	brain expressed X-linked 2
Synonyms	AL024066,Bex1
General protein information	Preferred Names brain expressed X-linked 2 Names protein BEX2 brain-expressed X-linked protein 2 homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X F1\|X 57.37 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009749.2	NP_033879.1	protein BEX2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	BEX1	XP_003317633.1
Rattus norvegicus (Norway rat)	Bex2	NP_001070903.1
Mus musculus (house mouse)	Bex2	NP_033879.1
Homo sapiens (human)	BEX1	NP_060946.3

Gene Ontology
Bibliography

Related articles in PubMed

Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.
Hu Z, Wang Y, Huang F, Chen R, Li C, Wang F, Goto J, Kwiatkowski DJ, Wdzieczak-Bakala J, Tu P, Liu J, Zha X, Zhang H
The Journal of biological chemistry290(42)25756-65(2015 Oct)

Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
Ito K, Yamazaki S, Yamamoto R, Tajima Y, Yanagida A, Kobayashi T, Kato-Itoh M, Kakuta S, Iwakura Y, Nakauchi H, Kamiya A
The Journal of biological chemistry289(43)29892-911(2014 Oct)

A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice.
Zhou J, McCarrey JR, Wang PJ
Biology of reproduction88(6)159(2013 Jun)

Gene expression profiles in genetically different mice infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU.
Ismail HA, Quan JH, Wei Z, Choi IW, Cha GH, Shin DW, Lee YH, Song CJ
The Korean journal of parasitology50(1)7-13(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

enhanced STAT3/NF-kappaB-BEX2-VEGF signaling pathway contributes to hyperactive mTOR-induced tumorigenesis
Title: Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.

These results suggest the significance and potential applications of Bex2 in studies of endocrine and stem/progenitor cells.
Title: Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.

Expression of ALDH1A2, BEX2, EGR2, CCL3 and PLAU are upregulated in Toxoplasma gondiisusceptible C57BL/6 mice.
Title: Gene expression profiles in genetically different mice infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU.

Bex immunoreactivity (ir) was primarily localized to neuronal cells within the olfactory epithelium, bulb, peri/paraventricular nuclei, suprachiasmatic nucleus, hypothalamus, thalamus, hippocampus, and cerebellum.
Title: Immunolocalization of Bex protein in the mouse brain and olfactory system.

We report the identification of an olfactory marker protein binding partner, Bex2, by phage-display screening of an olfactory mucosal cDNA-library
Title: Identification of members of the Bex gene family as olfactory marker protein (OMP) binding partners.

The following Bex2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bex2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04763	NM_009749.2 Latest version!	Mus musculus brain expressed X-linked 2 (Bex2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bex2 ( NM_009749.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033879.1 Mus musculus brain expressed X-linked 2 (Bex2), mRNA.

Price & Availability↑

CloneID	OMu04763
Clone ID Related Accession (Same CDS sequence)	NM_009749.2
Accession Version	NM_009749.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	protein BEX2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY294227.1, AK132005.1 and AL671914.9. On Jun 17, 2010 this sequence version replaced NM_009749.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU560039.1, BU559835.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTCCA AAGTGGAACA AGGCGTGAAA AATCTCAACA TGGAGAATGA CCATCAGGAA 
AAGGAGGAAA AGGAAGAAAA GCCACAGGAT GCTAGCAAAA GGGATCCGAT TGTGGCCCTG 
CCTTTCGAAG CTGGAGACTA CTACGTGCCT AGAGGAGGTC GCAGGCGGTT CCGGGTTCGG 
CAGCCCATCG TGCACTACAG ATGGGACCTG ATGCATAGGG TTGGGGAGCC CCAGGGAAGG 
ATGAGAGAGG AGAACGTACA GAGGTTTGGG GATGATGTGA GACAGCTCAT GGAGAAGCTG 
AGGGAAAGGC AGCTGAGCCA CAGCCTGCGG GCGGTTAGCA CTGACCCGCC TCATCATGAC 
CACCATGATG AGTTTTGCCT TATGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033879.1
CDS	265..654
Translation	MESKVEQGVKNLNMENDHQEKEEKEEKPQDASKRDPIVALPFEAGDYYVPRGGRRRFRVRQPIVHYRWDLMHRVGEPQGRMREENVQRFGDDVRQLMEKLRERQLSHSLRAVSTDPPHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_009749.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus brain expressed X-linked 2 (Bex2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009749.2

ORF Insert Sequence:

ATGGAGTCCA AAGTGGAACA AGGCGTGAAA AATCTCAACA TGGAGAATGA CCATCAGGAA 
AAGGAGGAAA AGGAAGAAAA GCCACAGGAT GCTAGCAAAA GGGATCCGAT TGTGGCCCTG 
CCTTTCGAAG CTGGAGACTA CTACGTGCCT AGAGGAGGTC GCAGGCGGTT CCGGGTTCGG 
CAGCCCATCG TGCACTACAG ATGGGACCTG ATGCATAGGG TTGGGGAGCC CCAGGGAAGG 
ATGAGAGAGG AGAACGTACA GAGGTTTGGG GATGATGTGA GACAGCTCAT GGAGAAGCTG 
AGGGAAAGGC AGCTGAGCCA CAGCCTGCGG GCGGTTAGCA CTGACCCGCC TCATCATGAC 
CACCATGATG AGTTTTGCCT TATGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.
The Journal of biological chemistry290(42)25756-65(2015 Oct)
Hu Z,Wang Y,Huang F,Chen R,Li C,Wang F,Goto J,Kwiatkowski DJ,Wdzieczak-Bakala J,Tu P,Liu J,Zha X,Zhang H

Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
The Journal of biological chemistry289(43)29892-911(2014 Oct)
Ito K,Yamazaki S,Yamamoto R,Tajima Y,Yanagida A,Kobayashi T,Kato-Itoh M,Kakuta S,Iwakura Y,Nakauchi H,Kamiya A

A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice.
Biology of reproduction88(6)159(2013 Jun)
Zhou J,McCarrey JR,Wang PJ

Gene expression profiles in genetically different mice infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU.
The Korean journal of parasitology50(1)7-13(2012 Mar)
Ismail HA,Quan JH,Wei Z,Choi IW,Cha GH,Shin DW,Lee YH,Song CJ