Adprh cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adprh
Entrez Gene ID	11544
Full Name	ADP-ribosylarginine hydrolase
Synonyms	Arh1
General protein information	Preferred Names ADP-ribosylarginine hydrolase Names ADP-ribosylarginine hydrolase ADP-ribose-L-arginine cleaving enzyme [Protein ADP-ribosylarginine] hydrolase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 B4

mRNA and Protein(s)

mRNA	Protein	Name
NM_007414.3	NP_031440.1	ADP-ribosylarginine hydrolase

Pathways from BioSystems

Homologies

	ADPRH	XP_001109848.1
Canis lupus familiaris (dog)	ADPRH	XP_003640166.2
Gallus gallus (chicken)	ADPRH	NP_001265030.1
Rattus norvegicus (Norway rat)	Adprh	NP_899154.2
Xenopus tropicalis (tropical clawed frog)	adprh	NP_001107365.1
Homo sapiens (human)	ADPRH	NP_001116.1
Pan troglodytes (chimpanzee)	ADPRH	XP_001163408.1
Bos taurus (cattle)	ADPRH	NP_001033643.1
Mus musculus (house mouse)	Adprh	NP_031440.1

Gene Ontology
Bibliography

Related articles in PubMed

CD38 knockout suppresses tumorigenesis in mice and clonogenic growth of human lung cancer cells.
Bu X, Kato J, Hong JA, Merino MJ, Schrump DS, Lund FE, Moss J
Carcinogenesis(2017 Dec)

ADP-ribosylarginine hydrolase regulates cell proliferation and tumorigenesis.
Kato J, Zhu J, Liu C, Stylianou M, Hoffmann V, Lizak MJ, Glasgow CG, Moss J
Cancer research71(15)5327-35(2011 Aug)

Enhanced sensitivity to cholera toxin in ADP-ribosylarginine hydrolase-deficient mice.
Kato J, Zhu J, Liu C, Moss J
Molecular and cellular biology27(15)5534-43(2007 Aug)

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.
Li H, Bishop KM, O'Leary DD
Molecular and cellular neurosciences33(2)136-49(2006 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ARH1(-/-) and ARH1(+/-) mice spontaneously develop lymphomas, adenocarcinomas, & metastases more frequently than wild-type. Proper control of protein ADP-ribosylation levels affected by ARH1 is essential for cancer suppression.
Title: ADP-ribosylarginine hydrolase regulates cell proliferation and tumorigenesis.

Cholera toxin-catalyzed ADP-ribosylation of cell proteins can be counteracted by ADPRH, which could function as a modifier gene in disease.
Title: Enhanced sensitivity to cholera toxin in ADP-ribosylarginine hydrolase-deficient mice.

ADP-ribosylarginine hydrolase promoter activity pattern and involvement of Sp transcription factors are consistent with prior observations of widespread hydrolase expression in mammalian tissues.
Title: Genomic organization and promoter analysis of the mouse ADP-ribosylarginine hydrolase gene.

The following Adprh gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adprh cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00131	NM_007414.3 Latest version!	Mus musculus ADP-ribosylarginine hydrolase (Adprh), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adprh ( NM_007414.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031440.1 Mus musculus ADP-ribosylarginine hydrolase (Adprh), mRNA.

Price & Availability↑

CloneID	OMu00131
Clone ID Related Accession (Same CDS sequence)	NM_007414.3
Accession Version	NM_007414.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	ADP-ribosylarginine hydrolase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ155232.1, AK153498.1 and CAAA01037235.1. On Feb 15, 2006 this sequence version replaced NM_007414.2. ##Evidence-Data-START## Transcript exon combination :: AF244347.1, AK146280.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTGGGG GGCTGATTGA GAGGTATGTG GCTGCCATGG TGCTGAGCGC GGCTGGAGAT 
ACCTTGGGCT ACTTCAACGG GAAGTGGGAG TTCATTCGGG ATGGGGAGAC GATACACCAG 
CAGTTGGCCC AGATGGGTGA CTTGGAAGCC ATAGATGTGG CACGATGGAG AGTCAGTGAT 
GATACCGTCA TGCACCTGGC CACAGCGGAG GCCCTCATGG AAGCCGGCCA GTCCCCGGAT 
TTGCCTCGGC TGTATTCCCT ACTAGCCAAA CATTACCGGG ACTGCATGGG AGACATGGAT 
GGCCGGGCAC CAGGTGGTGC TTGCATGCAG AACGCCATGC TGCTACAGCC CAACAGGGCC 
GACGGCTATA GGATTCCCTT CAACAGTCAC GAGGGTGGCT GCGGGGCTGC CATGCGCGCC 
ATGTGCATCG GGCTGAGGTT CCCCCACCCC AGCCAACTGG ATCTGCTGAT CCAAGTGAGC 
ATCGAGAGCG GCCGGATGAC CCACCACCAC CCCACGGGCT ACCTCGGCAG CCTTGCGTCC 
GCTCTTTTTA CGGCATATGC CGTGAATGGC AAGTCACCAT GGCAGTGGGG AAAAGGGCTA 
ATGGAGGTGC TGCCTGAAGC CAAAAAGTAC ATCACTCAGT CAGGCTACTT TGTGAAGGAG 
AATCTTCAAC ACTGGTCCTA CTTCGAGAAA GAATGGGAAA AGTACCTGGA GCTTAGAGGA 
ATTTTGGACG GCAACTCGGC TCCCGTCTTC CCGCAGCCCT TTGGTGTGAA GGAAAGGGAT 
CAGTTCTACA TCGACGTGAG CTACTCGGGC TGGGGTGGCA GCAGCGGACA CGATGCCCCC 
ATGATTGCCT ACGATGCCCT CCTGGCCGCG GGGGATTCCT GGAAGGAGCT CGCACACAGA 
GCCTTCTTCC ACGGTGGAGA CAGTGATTCC ACGGCCGCCA TTGCTGGCTG CTGGTGGGGA 
GTTATGTACG GCTTTAAAGG CGTAAATCCC GCCAACTACG AGAAGCTCGA ATACCGACAG 
CGGCTAGAAG AGGCCGGAAG AGCTTTGTAT TCTCTCGGGT CAAAAGAAGA CCCTGTATTA 
GATCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031440.1
CDS	204..1292
Translation	MGGGLIERYVAAMVLSAAGDTLGYFNGKWEFIRDGETIHQQLAQMGDLEAIDVARWRVSDDTVMHLATAEALMEAGQSPDLPRLYSLLAKHYRDCMGDMDGRAPGGACMQNAMLLQPNRADGYRIPFNSHEGGCGAAMRAMCIGLRFPHPSQLDLLIQVSIESGRMTHHHPTGYLGSLASALFTAYAVNGKSPWQWGKGLMEVLPEAKKYITQSGYFVKENLQHWSYFEKEWEKYLELRGILDGNSAPVFPQPFGVKERDQFYIDVSYSGWGGSSGHDAPMIAYDALLAAGDSWKELAHRAFFHGGDSDSTAAIAGCWWGVMYGFKGVNPANYEKLEYRQRLEEAGRALYSLGSKEDPVLDP

Target ORF information:

RefSeq Version	NM_007414.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylarginine hydrolase (Adprh), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007414.3

ORF Insert Sequence:

ATGGGTGGGG GGCTGATTGA GAGGTATGTG GCTGCCATGG TGCTGAGCGC GGCTGGAGAT 
ACCTTGGGCT ACTTCAACGG GAAGTGGGAG TTCATTCGGG ATGGGGAGAC GATACACCAG 
CAGTTGGCCC AGATGGGTGA CTTGGAAGCC ATAGATGTGG CACGATGGAG AGTCAGTGAT 
GATACCGTCA TGCACCTGGC CACAGCGGAG GCCCTCATGG AAGCCGGCCA GTCCCCGGAT 
TTGCCTCGGC TGTATTCCCT ACTAGCCAAA CATTACCGGG ACTGCATGGG AGACATGGAT 
GGCCGGGCAC CAGGTGGTGC TTGCATGCAG AACGCCATGC TGCTACAGCC CAACAGGGCC 
GACGGCTATA GGATTCCCTT CAACAGTCAC GAGGGTGGCT GCGGGGCTGC CATGCGCGCC 
ATGTGCATCG GGCTGAGGTT CCCCCACCCC AGCCAACTGG ATCTGCTGAT CCAAGTGAGC 
ATCGAGAGCG GCCGGATGAC CCACCACCAC CCCACGGGCT ACCTCGGCAG CCTTGCGTCC 
GCTCTTTTTA CGGCATATGC CGTGAATGGC AAGTCACCAT GGCAGTGGGG AAAAGGGCTA 
ATGGAGGTGC TGCCTGAAGC CAAAAAGTAC ATCACTCAGT CAGGCTACTT TGTGAAGGAG 
AATCTTCAAC ACTGGTCCTA CTTCGAGAAA GAATGGGAAA AGTACCTGGA GCTTAGAGGA 
ATTTTGGACG GCAACTCGGC TCCCGTCTTC CCGCAGCCCT TTGGTGTGAA GGAAAGGGAT 
CAGTTCTACA TCGACGTGAG CTACTCGGGC TGGGGTGGCA GCAGCGGACA CGATGCCCCC 
ATGATTGCCT ACGATGCCCT CCTGGCCGCG GGGGATTCCT GGAAGGAGCT CGCACACAGA 
GCCTTCTTCC ACGGTGGAGA CAGTGATTCC ACGGCCGCCA TTGCTGGCTG CTGGTGGGGA 
GTTATGTACG GCTTTAAAGG CGTAAATCCC GCCAACTACG AGAAGCTCGA ATACCGACAG 
CGGCTAGAAG AGGCCGGAAG AGCTTTGTAT TCTCTCGGGT CAAAAGAAGA CCCTGTATTA 
GATCCCTAG