Tas2r116 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tas2r116
Entrez Gene ID	112408
Full Name	taste receptor, type 2, member 116
Synonyms	T2R16,TRB1,TRB4,Tas2r14,Tas2r16,Tas2r7,mGR16,mt2r56
General protein information	Preferred Names taste receptor, type 2, member 116 Names taste receptor type 2 member 116 T2R116 candidate taste receptor mt2r56 tas2r116 taste receptor, type 2, member 14 taste receptor, type 2, member 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 G1\|6 64.03 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_053212.1	NP_444442.1	taste receptor type 2 member 116

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tas2r116	NP_444442.1
Rattus norvegicus (Norway rat)	Tas2r116	NP_001160151.1

Gene Ontology
Bibliography

Related articles in PubMed

?2-Adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function.
Kim D, Pauer SH, Yong HM, An SS, Liggett SB
The Journal of biological chemistry291(34)17616-28(2016 08)

Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.
Nelson TM, Munger SD, Boughter JD Jr
BMC genetics632(2005 Jun)

Evolutionary relationships of the Tas2r receptor gene families in mouse and human.
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ
Physiological genomics14(1)73-82(2003 Jun)

Adaptive diversification of bitter taste receptor genes in Mammalian evolution.
Shi P, Zhang J, Yang H, Zhang YP
Molecular biology and evolution20(5)805-14(2003 May)

A family of candidate taste receptors in human and mouse.
Matsunami H, Montmayeur JP, Buck LB
Nature404(6778)601-4(2000 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Thus the beta2AR acts as a double-edged sword: increasing TAS2R14 cell surface expression, but when activated by beta-agonist, partially offsetting the expression phenotype by direct receptor:receptor desensitization of TAS2R14 function.
Title: ?2-Adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function.

The following Tas2r116 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tas2r116 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58134	NM_053212.1 Latest version!	Mus musculus taste receptor, type 2, member 116 (Tas2r116), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tas2r116 ( NM_053212.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_444442.1 Mus musculus taste receptor, type 2, member 116 (Tas2r116), mRNA.

Price & Availability↑

CloneID	OMu58134
Clone ID Related Accession (Same CDS sequence)	NM_053212.1
Accession Version	NM_053212.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	taste receptor type 2 member 116
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BK001084.1.

ATGAATGGTG TCCTACAGGT TACATTTATA GTCATTTTGA GTGTGGAATT TATAATTGGC 
ATCTTTGGCA ATGGATTCAT AGCGGTGGTG AACATAAAGG ACTTGGTCAA GGGAAGGAAG 
ATCTCTTCAG TGGATCAGAT CCTCACTGCT CTGGCCATCT CCAGAATTGC ACTGCTGTGG 
TTAATATTAG TAAGTTGGTG GATATTTGTG CTTTACCCAG GACAATGGAT GACTGATAGA 
AGAGTTAGCA TAATGCACAG TATATGGACA ACATTCAACC AGAGTAGTCT CTGGTTTGCT 
ACAAGTCTCA GCATCTTTTA TTTTTTCAAG ATAGCAAATT TTTCCAACCC TATTTTTCTT 
TATTTAAAGG TCAGACTTAA AAAAGTCATG ATAGGGACAT TGATAATGTC TTTGATTCTC 
TTTTGTTTAA ATATTATCAT TATGAATGCA CCTGAGAACA TTTTAATCAC TGAATATAAT 
GTATCTATGT CTTACAGCTT GATTTTGAAT AACACACAGC TTTCTATGCT GTTTCCATTT 
GCCAACACCA TGTTTGGGTT CATACCTTTT GCTGTGTCAC TGGTCACTTT TGTCCTTCTT 
GTTTTCTCCC TGTGGAAACA TCAGAGAAAG ATGCAACACA GTGCCCATGG ATGCAGAGAT 
GCCAGCACTA AGGCCCACAT CAGAGCCTTG CAGACATTGA TTGCCTCCCT CCTCCTGTAT 
TCCATTTTCT TCCTGTCTCA TGTTATGAAG GTTTGGAGTG CTCTGCTTCT GGAGAGGACA 
CTCCTGCTTT TGATCACACA GGTTGCAAGA ACAGCTTTTC CGTCAGTGCA CTCCTGGGTC 
CTGATTCTGG GCAATGCTAA GATGAGAAAG GCTTCTCTCT ATGTATTCCT GTGGCTGAGG 
TGCAGGCACA AAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444442.1
CDS	1..918
Translation	MNGVLQVTFIVILSVEFIIGIFGNGFIAVVNIKDLVKGRKISSVDQILTALAISRIALLWLILVSWWIFVLYPGQWMTDRRVSIMHSIWTTFNQSSLWFATSLSIFYFFKIANFSNPIFLYLKVRLKKVMIGTLIMSLILFCLNIIIMNAPENILITEYNVSMSYSLILNNTQLSMLFPFANTMFGFIPFAVSLVTFVLLVFSLWKHQRKMQHSAHGCRDASTKAHIRALQTLIASLLLYSIFFLSHVMKVWSALLLERTLLLLITQVARTAFPSVHSWVLILGNAKMRKASLYVFLWLRCRHKE

Target ORF information:

RefSeq Version	NM_053212.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus taste receptor, type 2, member 116 (Tas2r116), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053212.1

ORF Insert Sequence:

ATGAATGGTG TCCTACAGGT TACATTTATA GTCATTTTGA GTGTGGAATT TATAATTGGC 
ATCTTTGGCA ATGGATTCAT AGCGGTGGTG AACATAAAGG ACTTGGTCAA GGGAAGGAAG 
ATCTCTTCAG TGGATCAGAT CCTCACTGCT CTGGCCATCT CCAGAATTGC ACTGCTGTGG 
TTAATATTAG TAAGTTGGTG GATATTTGTG CTTTACCCAG GACAATGGAT GACTGATAGA 
AGAGTTAGCA TAATGCACAG TATATGGACA ACATTCAACC AGAGTAGTCT CTGGTTTGCT 
ACAAGTCTCA GCATCTTTTA TTTTTTCAAG ATAGCAAATT TTTCCAACCC TATTTTTCTT 
TATTTAAAGG TCAGACTTAA AAAAGTCATG ATAGGGACAT TGATAATGTC TTTGATTCTC 
TTTTGTTTAA ATATTATCAT TATGAATGCA CCTGAGAACA TTTTAATCAC TGAATATAAT 
GTATCTATGT CTTACAGCTT GATTTTGAAT AACACACAGC TTTCTATGCT GTTTCCATTT 
GCCAACACCA TGTTTGGGTT CATACCTTTT GCTGTGTCAC TGGTCACTTT TGTCCTTCTT 
GTTTTCTCCC TGTGGAAACA TCAGAGAAAG ATGCAACACA GTGCCCATGG ATGCAGAGAT 
GCCAGCACTA AGGCCCACAT CAGAGCCTTG CAGACATTGA TTGCCTCCCT CCTCCTGTAT 
TCCATTTTCT TCCTGTCTCA TGTTATGAAG GTTTGGAGTG CTCTGCTTCT GGAGAGGACA 
CTCCTGCTTT TGATCACACA GGTTGCAAGA ACAGCTTTTC CGTCAGTGCA CTCCTGGGTC 
CTGATTCTGG GCAATGCTAA GATGAGAAAG GCTTCTCTCT ATGTATTCCT GTGGCTGAGG 
TGCAGGCACA AAGAATGA