LOC108677995 cDNA ORF clone, Hyalella azteca

Gene
Clones
gRNAs

Summary

Gene Symbol	LOC108677995
Entrez Gene ID	108677995
Full Name	uncharacterized LOC108677995
Gene Type	protein-coding
Organism	Hyalella azteca

mRNA and Protein(s)

mRNA	Protein	Name
XM_018166319.1	XP_018021808.1	uncharacterized protein LOC108677995

Pathways from BioSystems
Gene Ontology

The following LOC108677995 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LOC108677995 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHy07551	XM_018166319.1 Latest version!	Hyalella azteca uncharacterized LOC108677995 (LOC108677995), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$713.30 $1019.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LOC108677995 ( XM_018166319.1 ) cDNA ORF clone, Hyalella azteca -> XP_018021808.1 Hyalella azteca uncharacterized LOC108677995 (LOC108677995), mRNA.

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CloneID	OHy07551
Clone ID Related Accession (Same CDS sequence)	XM_018166319.1
Accession Version	XM_018166319.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-09-15
Organism	Hyalella azteca
Product	uncharacterized protein LOC108677995
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_017248129.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Hyalella azteca Annotation Release 100 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACCC TCACTGGAGA TGTCAGAGTC TGGAGTCTAA GAGAAGATGT TGTTGTGAGA 
GATGCTGATT TTTCAGCTGT CAGATATCAA GACAAGACTG CTGTTAGGAA GGAGCGTATC 
TATTATGAAG AAAAAAAGCG GTACATTGAG GCAAGAGGAG GCTGTGCTGC TCCTAAAAAC 
AGTCGCCCCA CTCGTCTCAG AGATGCCATA AAAGAGTTTG AGGAATTGCT GGGAGCAGAA 
CAGGTGGTGT GGAGTAGCTG GGGTGCTACT AGCACCGAGT TTGCCACACC ATCTGATGAC 
GCACATGAAG CTCTGGCTCA GCATCATGAA CCTTGCAGAG TTTATTATAT GGTGCTGGCG 
TCTGGTGTTG TGTGTACAGC TCTGCTCAGT GCCGTGTCAG GCGATCTGCG TGGTCTGACT 
TCTGACAAGT ACATGACTGG CAAGCTGCTC TCTGAACACC CTGCTCATGC TGCTATCACA 
TCAAACCATC TGGTGATCAC TTACAATGAC TCCCGCGTGT CAGTGCTCCA CATGGATGCC 
TACACTCCTC CATGTGCCTT GCCACTGCCA CTCTCCCAGA CCGGGGACTC CACGACAGGC 
TACACGGCGC CTTTATTCTC TTCACGACAT CCTGCCCTTT ACACTGCGCA GCTCGCTGGC 
CCTCATGGCC GCCGCTTTCA GAGGAAAATT TCTGCTAACT CTACGGGAGA CATGATTGCT 
GTGTGGTGGG AGCGATCCGA AGACGAAGTT TATCCTTGGT CTCCTCTGGA GCGTGACTGC 
AGGGACAGAG CAAACATTCT TATTTATGGT CTTCGTTGCG GTCAGCTGTC TTTGTTCGGG 
CATGCGCGGT CACACTTGCC GCCCCTCAGT GTTGCGTTCA GCGCGAGAGA CGCCAATGTT 
TTGCTTAGTG TTGAGCAAGG CTTTGACAAG AAGGGTGGCG TCAGTGTTCT CTCTGTGGTT 
TATAAGGTTG GAGATAGCAA GGTAGAGCGT GTTTCCGTCA CAACCATCCC GTTGGAGGCA 
CCGGTAGCAA GCCACAGCTA CAGCCCAAAG GAGGACCGAC TGTTTTTGGC ATGCAACAAC 
GGCGTCCTTG CGCTGCACTC GCATGCATCC ACGCACCTCA CGAGAGCCGC TCTCAGCCCC 
ACGCACGTCA CCTGGCTGCA GCCTGGGGCT TTACTTGCTG TTGCTAATGA CAGAGGACAA 
GTCCAGTTCT TTGACATGGC TCTGAGTCTT GTCAGGGTGC AACTTGGAGG AGAAGATGGG 
CTGCCACTTC GTCTGCTCGA CTTTGCTGAC TATTTTTGCC ACCAGCCATC TCTTCGAGAT 
ATTTCTTGGG CTCCCGCTCC GGTCGTCTTC AGTTGTAGTG ACACAAAACG AAACTACAAC 
GCTAATGTGA AGCGCTACTT GGACGTCCGG GAGCAACATT CTTCCTTATT ACTGGTGTTG 
CAGTACGTGC GAGGTCCGTT GCTTTGCATT CGTTTCAATG CTCCTCACTT TTCACTCACT 
CATCCCGTGT CCAACCCTCG GCTGGATGAC CTCAGCTTCT CGTCTTCACT AAGCCCAAAC 
ACCGAGGACT CGGATTCGCA CAACACCTCG CAGATATCTT ACGGCACAAC CACGTCCAAT 
TCTTCGGGCT CTATTGCTAC CAAGAGTTCA GTTAATAACC AAAATAGTTC TCAGAATACT 
ACAGGAAATT CATCTGGTCA TGCATCAAAG GACGACCAAG GCTTGACTGC TCATTACTGC 
AGCATTTGTC CGGACGTCCT AGTTGGCGAG TATCTTCGTC ACGGCCAAGT AGAAGAAGCC 
ATCAACCTCA GCAGGTCTCT GTGCTGGGAA CAAGATGGTG GTGCTGCTCT GAAATGCATC 
AGCAGTGTCG TCAACTACAT CATTAGACGA GGACAAATAT CCCGACCTTC AAATAGTGTA 
ACTCCGCATT CTCCAGCACA AGATGACGGG CAAGACAGAA CATCCGCTCT CACGGTACCA 
TCACTAAATT CGTCTCCTGG GCTTTGGGAA ACTCGTATCT TGAATGCGGC CGCTGTTTTA 
TCCTCGGGCT TTCTCTCACC ATCGGCACAC CTCACGCCTG CCACTGAAGA GCTCTACGGC 
CCTCCTGTGC GAGCGCTTGC CCGACGATTG TTCTTCAAGT TACTCAGGAG TGCGTGCCTG 
CAGTCTGCGT TCTCTCTGGC CCAGGATCTG GGTGACCCCG ACTGCTTTGT CAGGCTGCAC 
CGGTCCGCTG AGCGGGCGGG CTTACCGCAG CTCGCAGCGC AGTCTCTGCG ACACGCAAAC 
AGCCTCCGCT CCTCATCAAC GTCTTCTTGC TCTGGCAGCT GCTCGCACAG CGGCAGCTCG 
TATTCTGGCA GCAGCAGCGG CAGCTCGTGC TGCGATGAGG ACTGTTCACA TTCCAGCTGT 
ACAGACGGCA GCACCAGCAG CAGTGGCTCT GAGTCTTGCT CCACCTGCTC CGACTCTTCC 
AGTGACTCAG ACTCACATGA AGGGTTGGAG GAGCGTGGAG AACGCCAGGG TGGGGATGGG 
CGCGAAAGTG AAGGCCCTGG AAGTTCGCAA CACGACGGAG TTTCCAGAAC CCCTGACGAC 
GCTCGCGCTA TTCCCGACCG ACCATTGTTC GTCCAGCAGC CCACGAGTGT TCCTCCGCCT 
GTCCCTGCCC CCATCCTGCC GAGAGACTCG AATATTTCTT CAGTAGAGGC CGTAGCCTCG 
TCCACTATGA CTTACTATGA CCCGCCACCC TACACTTCCC ATAATTTCAC TCGTACCGCT 
TCTGTAATTA ATCCTTCTGG AACCTCAAAT GATGTCACGG AATTCACTTC GAACTCTGGC 
ACTTTGAAAG CAGCTAATGT TCCGAAGCCA GAAAATGTGA TTCGTGGCCT CAAACCTACG 
CTTTCCCATA CTACGGTTTT GAAAAACTCG ACCAAGTCTT CTCAACTTCA TGACATGAAT 
TTTAAAATCG ATCTAAAAGA TGATCTTCAA ACCACACGCG CCGTTCCAAC CACACAATAT 
AATGACGCTT ACGTTCCAAG CTCTGCTCAC CAGCTCGTCG CCAACCAGTA TAGTAACTCA 
AGAAATGTTA CAGTTCTTAA CACCCAATCA AATGCGATGC GTCACTATGG GCCTCTGGAA 
AATTCTGGGA CATCTTCTGA TCAAACTGGT GATCCTTACT CGAAATCGTC CGGTAATCCA 
GTGAGCGCAA TAACGTCTAT GGACGGTAAA GTAACTATCA ACATAACTCA GAACGAGAGC 
CTCATAAATG TCCATCGCAA CACTAAACGG TCGAGCCACC GCAAGAGCAA AACAAACTCT 
CGCAAACGCA ACGAAAGCTC GTCCGTGAGC GAAGAGTTTT TTCTAGAAAA CAAGAGCGCC 
GTGTCTGAGC ATCGTCATTC GGGGAAAGAG ATAGAAGTAT GTCACTTCGA ACATAGTCAT 
GTGGCCGCTC CCAAGTCTCG GCATGACAAG AAAAAACAGG AAGTCAATAT TCCATTTAAA 
AATCGTCGGT CCCAACGAAA TCTTACGGAT GCTATGGATG CCGCCGATTC TGCTATTGCA 
GCATTACATT CTGTCAGGAA ATCCATGGCC AATGAGCCTG ACTTAAAAGC TGTTCCAACG 
ACTGTGGGGT CAAATGTTTT TCAAAATTCC GATCCAAAAA ACCACACCCT TAGTATTGCT 
GAGAGTAGTC AAAATACAAC AGGGGCTTCC CACAATCTTG CATTAAGAAC TCTGCAGTCA 
GTGCCTAATA CCTTTGAAAA ATCCTCATTT GTCCCCAAAG AGACTCTTCC TATGGATGTT 
GGTTATTACA ATGAAGATAC TATTGACGAA GAAATGAACA GGAGCCTGTA TCAAGATCTT 
TCAACGGAAG AAGAGGAGGG CGGAGGTACC GTTAAAGTTG TTCATTTTGG CGTCGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_018021808.1
CDS	83..3982
Translation	MATLTGDVRVWSLREDVVVRDADFSAVRYQDKTAVRKERIYYEEKKRYIEARGGCAAPKNSRPTRLRDAIKEFEELLGAEQVVWSSWGATSTEFATPSDDAHEALAQHHEPCRVYYMVLASGVVCTALLSAVSGDLRGLTSDKYMTGKLLSEHPAHAAITSNHLVITYNDSRVSVLHMDAYTPPCALPLPLSQTGDSTTGYTAPLFSSRHPALYTAQLAGPHGRRFQRKISANSTGDMIAVWWERSEDEVYPWSPLERDCRDRANILIYGLRCGQLSLFGHARSHLPPLSVAFSARDANVLLSVEQGFDKKGGVSVLSVVYKVGDSKVERVSVTTIPLEAPVASHSYSPKEDRLFLACNNGVLALHSHASTHLTRAALSPTHVTWLQPGALLAVANDRGQVQFFDMALSLVRVQLGGEDGLPLRLLDFADYFCHQPSLRDISWAPAPVVFSCSDTKRNYNANVKRYLDVREQHSSLLLVLQYVRGPLLCIRFNAPHFSLTHPVSNPRLDDLSFSSSLSPNTEDSDSHNTSQISYGTTTSNSSGSIATKSSVNNQNSSQNTTGNSSGHASKDDQGLTAHYCSICPDVLVGEYLRHGQVEEAINLSRSLCWEQDGGAALKCISSVVNYIIRRGQISRPSNSVTPHSPAQDDGQDRTSALTVPSLNSSPGLWETRILNAAAVLSSGFLSPSAHLTPATEELYGPPVRALARRLFFKLLRSACLQSAFSLAQDLGDPDCFVRLHRSAERAGLPQLAAQSLRHANSLRSSSTSSCSGSCSHSGSSYSGSSSGSSCCDEDCSHSSCTDGSTSSSGSESCSTCSDSSSDSDSHEGLEERGERQGGDGRESEGPGSSQHDGVSRTPDDARAIPDRPLFVQQPTSVPPPVPAPILPRDSNISSVEAVASSTMTYYDPPPYTSHNFTRTASVINPSGTSNDVTEFTSNSGTLKAANVPKPENVIRGLKPTLSHTTVLKNSTKSSQLHDMNFKIDLKDDLQTTRAVPTTQYNDAYVPSSAHQLVANQYSNSRNVTVLNTQSNAMRHYGPLENSGTSSDQTGDPYSKSSGNPVSAITSMDGKVTINITQNESLINVHRNTKRSSHRKSKTNSRKRNESSSVSEEFFLENKSAVSEHRHSGKEIEVCHFEHSHVAAPKSRHDKKKQEVNIPFKNRRSQRNLTDAMDAADSAIAALHSVRKSMANEPDLKAVPTTVGSNVFQNSDPKNHTLSIAESSQNTTGASHNLALRTLQSVPNTFEKSSFVPKETLPMDVGYYNEDTIDEEMNRSLYQDLSTEEEEGGGTVKVVHFGVV

Target ORF information:

RefSeq Version	XM_018166319.1
Organism	Hyalella azteca
Definition	Hyalella azteca uncharacterized LOC108677995 (LOC108677995), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_018166319.1

ORF Insert Sequence:

ATGGCTACCC TCACTGGAGA TGTCAGAGTC TGGAGTCTAA GAGAAGATGT TGTTGTGAGA 
GATGCTGATT TTTCAGCTGT CAGATATCAA GACAAGACTG CTGTTAGGAA GGAGCGTATC 
TATTATGAAG AAAAAAAGCG GTACATTGAG GCAAGAGGAG GCTGTGCTGC TCCTAAAAAC 
AGTCGCCCCA CTCGTCTCAG AGATGCCATA AAAGAGTTTG AGGAATTGCT GGGAGCAGAA 
CAGGTGGTGT GGAGTAGCTG GGGTGCTACT AGCACCGAGT TTGCCACACC ATCTGATGAC 
GCACATGAAG CTCTGGCTCA GCATCATGAA CCTTGCAGAG TTTATTATAT GGTGCTGGCG 
TCTGGTGTTG TGTGTACAGC TCTGCTCAGT GCCGTGTCAG GCGATCTGCG TGGTCTGACT 
TCTGACAAGT ACATGACTGG CAAGCTGCTC TCTGAACACC CTGCTCATGC TGCTATCACA 
TCAAACCATC TGGTGATCAC TTACAATGAC TCCCGCGTGT CAGTGCTCCA CATGGATGCC 
TACACTCCTC CATGTGCCTT GCCACTGCCA CTCTCCCAGA CCGGGGACTC CACGACAGGC 
TACACGGCGC CTTTATTCTC TTCACGACAT CCTGCCCTTT ACACTGCGCA GCTCGCTGGC 
CCTCATGGCC GCCGCTTTCA GAGGAAAATT TCTGCTAACT CTACGGGAGA CATGATTGCT 
GTGTGGTGGG AGCGATCCGA AGACGAAGTT TATCCTTGGT CTCCTCTGGA GCGTGACTGC 
AGGGACAGAG CAAACATTCT TATTTATGGT CTTCGTTGCG GTCAGCTGTC TTTGTTCGGG 
CATGCGCGGT CACACTTGCC GCCCCTCAGT GTTGCGTTCA GCGCGAGAGA CGCCAATGTT 
TTGCTTAGTG TTGAGCAAGG CTTTGACAAG AAGGGTGGCG TCAGTGTTCT CTCTGTGGTT 
TATAAGGTTG GAGATAGCAA GGTAGAGCGT GTTTCCGTCA CAACCATCCC GTTGGAGGCA 
CCGGTAGCAA GCCACAGCTA CAGCCCAAAG GAGGACCGAC TGTTTTTGGC ATGCAACAAC 
GGCGTCCTTG CGCTGCACTC GCATGCATCC ACGCACCTCA CGAGAGCCGC TCTCAGCCCC 
ACGCACGTCA CCTGGCTGCA GCCTGGGGCT TTACTTGCTG TTGCTAATGA CAGAGGACAA 
GTCCAGTTCT TTGACATGGC TCTGAGTCTT GTCAGGGTGC AACTTGGAGG AGAAGATGGG 
CTGCCACTTC GTCTGCTCGA CTTTGCTGAC TATTTTTGCC ACCAGCCATC TCTTCGAGAT 
ATTTCTTGGG CTCCCGCTCC GGTCGTCTTC AGTTGTAGTG ACACAAAACG AAACTACAAC 
GCTAATGTGA AGCGCTACTT GGACGTCCGG GAGCAACATT CTTCCTTATT ACTGGTGTTG 
CAGTACGTGC GAGGTCCGTT GCTTTGCATT CGTTTCAATG CTCCTCACTT TTCACTCACT 
CATCCCGTGT CCAACCCTCG GCTGGATGAC CTCAGCTTCT CGTCTTCACT AAGCCCAAAC 
ACCGAGGACT CGGATTCGCA CAACACCTCG CAGATATCTT ACGGCACAAC CACGTCCAAT 
TCTTCGGGCT CTATTGCTAC CAAGAGTTCA GTTAATAACC AAAATAGTTC TCAGAATACT 
ACAGGAAATT CATCTGGTCA TGCATCAAAG GACGACCAAG GCTTGACTGC TCATTACTGC 
AGCATTTGTC CGGACGTCCT AGTTGGCGAG TATCTTCGTC ACGGCCAAGT AGAAGAAGCC 
ATCAACCTCA GCAGGTCTCT GTGCTGGGAA CAAGATGGTG GTGCTGCTCT GAAATGCATC 
AGCAGTGTCG TCAACTACAT CATTAGACGA GGACAAATAT CCCGACCTTC AAATAGTGTA 
ACTCCGCATT CTCCAGCACA AGATGACGGG CAAGACAGAA CATCCGCTCT CACGGTACCA 
TCACTAAATT CGTCTCCTGG GCTTTGGGAA ACTCGTATCT TGAATGCGGC CGCTGTTTTA 
TCCTCGGGCT TTCTCTCACC ATCGGCACAC CTCACGCCTG CCACTGAAGA GCTCTACGGC 
CCTCCTGTGC GAGCGCTTGC CCGACGATTG TTCTTCAAGT TACTCAGGAG TGCGTGCCTG 
CAGTCTGCGT TCTCTCTGGC CCAGGATCTG GGTGACCCCG ACTGCTTTGT CAGGCTGCAC 
CGGTCCGCTG AGCGGGCGGG CTTACCGCAG CTCGCAGCGC AGTCTCTGCG ACACGCAAAC 
AGCCTCCGCT CCTCATCAAC GTCTTCTTGC TCTGGCAGCT GCTCGCACAG CGGCAGCTCG 
TATTCTGGCA GCAGCAGCGG CAGCTCGTGC TGCGATGAGG ACTGTTCACA TTCCAGCTGT 
ACAGACGGCA GCACCAGCAG CAGTGGCTCT GAGTCTTGCT CCACCTGCTC CGACTCTTCC 
AGTGACTCAG ACTCACATGA AGGGTTGGAG GAGCGTGGAG AACGCCAGGG TGGGGATGGG 
CGCGAAAGTG AAGGCCCTGG AAGTTCGCAA CACGACGGAG TTTCCAGAAC CCCTGACGAC 
GCTCGCGCTA TTCCCGACCG ACCATTGTTC GTCCAGCAGC CCACGAGTGT TCCTCCGCCT 
GTCCCTGCCC CCATCCTGCC GAGAGACTCG AATATTTCTT CAGTAGAGGC CGTAGCCTCG 
TCCACTATGA CTTACTATGA CCCGCCACCC TACACTTCCC ATAATTTCAC TCGTACCGCT 
TCTGTAATTA ATCCTTCTGG AACCTCAAAT GATGTCACGG AATTCACTTC GAACTCTGGC 
ACTTTGAAAG CAGCTAATGT TCCGAAGCCA GAAAATGTGA TTCGTGGCCT CAAACCTACG 
CTTTCCCATA CTACGGTTTT GAAAAACTCG ACCAAGTCTT CTCAACTTCA TGACATGAAT 
TTTAAAATCG ATCTAAAAGA TGATCTTCAA ACCACACGCG CCGTTCCAAC CACACAATAT 
AATGACGCTT ACGTTCCAAG CTCTGCTCAC CAGCTCGTCG CCAACCAGTA TAGTAACTCA 
AGAAATGTTA CAGTTCTTAA CACCCAATCA AATGCGATGC GTCACTATGG GCCTCTGGAA 
AATTCTGGGA CATCTTCTGA TCAAACTGGT GATCCTTACT CGAAATCGTC CGGTAATCCA 
GTGAGCGCAA TAACGTCTAT GGACGGTAAA GTAACTATCA ACATAACTCA GAACGAGAGC 
CTCATAAATG TCCATCGCAA CACTAAACGG TCGAGCCACC GCAAGAGCAA AACAAACTCT 
CGCAAACGCA ACGAAAGCTC GTCCGTGAGC GAAGAGTTTT TTCTAGAAAA CAAGAGCGCC 
GTGTCTGAGC ATCGTCATTC GGGGAAAGAG ATAGAAGTAT GTCACTTCGA ACATAGTCAT 
GTGGCCGCTC CCAAGTCTCG GCATGACAAG AAAAAACAGG AAGTCAATAT TCCATTTAAA 
AATCGTCGGT CCCAACGAAA TCTTACGGAT GCTATGGATG CCGCCGATTC TGCTATTGCA 
GCATTACATT CTGTCAGGAA ATCCATGGCC AATGAGCCTG ACTTAAAAGC TGTTCCAACG 
ACTGTGGGGT CAAATGTTTT TCAAAATTCC GATCCAAAAA ACCACACCCT TAGTATTGCT 
GAGAGTAGTC AAAATACAAC AGGGGCTTCC CACAATCTTG CATTAAGAAC TCTGCAGTCA 
GTGCCTAATA CCTTTGAAAA ATCCTCATTT GTCCCCAAAG AGACTCTTCC TATGGATGTT 
GGTTATTACA ATGAAGATAC TATTGACGAA GAAATGAACA GGAGCCTGTA TCAAGATCTT 
TCAACGGAAG AAGAGGAGGG CGGAGGTACC GTTAAAGTTG TTCATTTTGG CGTCGTGTAA