TRIM56 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRIM56
Entrez Gene ID	81844
Full Name	tripartite motif containing 56
Synonyms	RNF109
General protein information	Preferred Names tripartite motif containing 56 Names E3 ubiquitin-protein ligase TRIM56 RING finger protein 109 RING-type E3 ubiquitin transferase TRIM56 tripartite motif-containing protein 56
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q22.1
Disorder MIM:	616996

mRNA and Protein(s)

mRNA	Protein	Name
XM_011516589.3	XP_011514891.1	E3 ubiquitin-protein ligase TRIM56 isoform X1
XM_011516589.2	XP_011514891.1	E3 ubiquitin-protein ligase TRIM56 isoform X1
NM_030961.3	NP_112223.1	E3 ubiquitin-protein ligase TRIM56
NM_030961.2	NP_112223.1	E3 ubiquitin-protein ligase TRIM56

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Trim56	NP_958761.1
	TRIM56	XP_001107405.1
Canis lupus familiaris (dog)	TRIM56	XP_005621064.1
Pan troglodytes (chimpanzee)	TRIM56	XP_527840.4
Bos taurus (cattle)	TRIM56	NP_001193503.1
Homo sapiens (human)	TRIM56	NP_112223.1

Gene Ontology
Bibliography

Related articles in PubMed

The ubiquitin ligase TRIM56 inhibits ovarian cancer progression by targeting vimentin.
Zhao L, Zhang P, Su XJ, Zhang B
Journal of cellular physiology233(3)2420-2425(2018 Mar)

TRIM56 Suppresses Multiple Myeloma Progression by Activating TLR3/TRIF Signaling.
Chen Y, Zhao J, Li D, Hao J, He P, Wang H, Zhang M
Yonsei medical journal59(1)43-50(2018 Jan)

Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA.
Fiskin E, Bhogaraju S, Herhaus L, Kalayil S, Hahn M, Dikic I
Nature communications814004(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TRIM56 is the ubiquitin ligase that is degrading vimentin in ovarian cancer cells, regulation cell migration and neoplasm invasiveness.
Title: The ubiquitin ligase TRIM56 inhibits ovarian cancer progression by targeting vimentin.

The C-Terminal Tail of TRIM56 Dictates Antiviral Restriction of Influenza A and B Viruses by Impeding Viral RNA Synthesis
Title: The C-Terminal Tail of TRIM56 Dictates Antiviral Restriction of Influenza A and B Viruses by Impeding Viral RNA Synthesis.

Altogether, TRIM56 is a versatile antiviral host factor that confers resistance to yellow fever virus, dengue virus serotype 2, and human coronavirus OC43 through overlapping and distinct molecular determinants
Title: Overlapping and distinct molecular determinants dictating the antiviral activities of TRIM56 against flaviviruses and coronavirus.

TRIM56 is an essential component of the TLR3 antiviral signaling pathway and reveal a novel role for TRIM56 in innate antiviral immunity.
Title: TRIM56 is an essential component of the TLR3 antiviral signaling pathway.

TRIM56 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.
Title: The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.

The following TRIM56 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRIM56 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu72997	NM_030961.3 Latest version!	Homo sapiens tripartite motif containing 56 (TRIM56), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu72997	XM_011516589.3 Latest version!	Homo sapiens tripartite motif containing 56 (TRIM56), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
View Old Accession Versions >>
OHu72997	XM_011516589.2	Homo sapiens tripartite motif containing 56 (TRIM56), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu72997	NM_030961.2	Homo sapiens tripartite motif containing 56 (TRIM56), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRIM56 ( NM_030961.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_112223.1 Homo sapiens tripartite motif containing 56 (TRIM56), mRNA.

Price & Availability↑

CloneID	OHu72997
Clone ID Related Accession (Same CDS sequence)	XM_011516589.3 , XM_011516589.2 , NM_030961.3 , NM_030961.2
Accession Version	NM_030961.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2268bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase TRIM56
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC005847.2, BC048194.1 and AC105446.4. On Nov 24, 2018 this sequence version replaced NM_030961.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC048194.1, SRR1660803.9512.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000306085.11/ ENSP00000305161.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTTTCCC ACGGGTCCTC GCCCTCCCTC CTGGAGGCCC TGAGCAGCGA CTTCCTGGCC 
TGTAAAATCT GCCTGGAGCA GCTGCGGGCA CCCAAGACAC TGCCCTGCCT GCATACCTAC 
TGCCAAGACT GCCTGGCACA GCTGGCGGAT GGCGGCCGCG TCCGCTGCCC CGAGTGCCGC 
GAGACAGTGC CTGTGCCGCC CGAGGGTGTG GCCTCCTTCA AGACCAACTT CTTCGTCAAT 
GGGCTGCTGG ACCTGGTGAA GGCCCGGGCC TGTGGAGACC TGCGTGCCGG GAAGCCAGCC 
TGTGCCCTGT GTCCCCTGGT GGGTGGCACC AGCACCGGGG GGCCGGCCAC GGCCCGGTGC 
CTGGACTGTG CCGATGACTT GTGCCAGGCC TGTGCCGACG GGCACCGCTG CACCCGCCAG 
ACCCACACCC ACCGCGTGGT GGACCTGGTG GGCTACAGGG CCGGGTGGTA TGATGAGGAG 
GCCCGGGAGC GCCAAGCGGC CCAGTGTCCC CAGCACCCCG GGGAGGCACT GCGCTTCCTG 
TGCCAGCCCT GCTCACAGTT GCTGTGCAGA GAGTGCCGCC TAGACCCCCA CCTGGACCAC 
CCCTGCCTGC CTCTGGCTGA AGCTGTGCGT GCCCGGAGGC CGGGCCTGGA GGGACTGCTG 
GCCGGTGTGG ACAATAACCT GGTGGAGCTG GAGGCAGCGC GGAGGGTGGA GAAGGAGGCG 
CTAGCCCGGC TGCGGGAGCA GGCGGCCCGG GTGGGGACTC AGGTGGAGGA GGCGGCTGAG 
GGCGTCCTCC GGGCCCTGCT GGCCCAGAAG CAGGAGGTGC TGGGGCAGCT ACGAGCCCAC 
GTGGAGGCTG CCGAAGAAGC TGCTCGGGAG AGGCTGGCGG AGCTTGAGGG CCGGGAGCAG 
GTGGCCAGGG CCGCAGCCGC CTTCGCCCGC CGGGTACTCA GCCTGGGGCG AGAGGCCGAG 
ATCCTCTCCC TGGAAGGGGC GATCGCACAG CGGCTCAGGC AGCTGCAGGG CTGCCCCTGG 
GCACCAGGCC CGGCCCCCTG CCTGCTCCCA CAGCTGGAGC TCCATCCTGG GCTCCTGGAC 
AAGAACTGCC ACCTTCTTCG GCTGTCCTTT GAGGAGCAGC AGCCCCAGAA GGATGGTGGG 
AAAGACGGAG CTGGTACCCA GGGAGGTGAG GAGAGCCAGA GCCGGAGGGA GGATGAGCCG 
AAGACTGAGA GACAGGGTGG AGTCCAGCCC CAGGCTGGAG ATGGAGCCCA GACCCCAAAA 
GAGGAAAAAG CCCAGACAAC CCGAGAAGAG GGAGCCCAGA CCTTGGAGGA GGACAGGGCC 
CAGACACCCC ACGAGGATGG AGGACCCCAG CCCCACAGGG GTGGCAGACC CAACAAGAAG 
AAAAAGTTCA AAGGCAGGCT CAAGTCAATT TCCCGGGAGC CCAGCCCAGC CCTGGGGCCG 
AATCTGGACG GCTCTGGCCT CCTCCCCAGA CCCATCTTTT ACTGCAGTTT CCCCACGCGG 
ATGCCTGGAG ACAAGCGGTC CCCCCGGATC ACCGGGCTCT GTCCCTTCGG TCCCCGGGAG 
ATCCTGGTGG CGGATGAGCA GAACCGGGCA CTGAAACGCT TCTCCCTCAA CGGCGACTAC 
AAGGGCACCG TGCCGGTCCC TGAGGGCTGC TCCCCTTGCA GCGTGGCCGC CCTGCAGAGC 
GCGGTGGCCT TCTCCGCTAG CGCACGGCTC TATCTCATCA ACCCCAACGG CGAAGTGCAG 
TGGCGCAGGG CCCTGAGCCT CTCCCAGGCC AGCCACGCGG TGGCGGCACT GCCTAGCGGG 
GACCGCGTGG CTGTCAGCGT GGCGGGCCAC GTGGAGGTGT ACAATATGGA AGGCAGCCTG 
GCCACCCGGT TCATTCCTGG AGGCAAGGCC AGCCGGGGCC TGCGGGCGCT GGTGTTTCTG 
ACCACCAGCC CCCAGGGGCA TTTCGTGGGG TCGGACTGGC AGCAGAATAG TGTGGTAATC 
TGTGATGGGC TGGGCCAGGT GGTTGGGGAG TACAAGGGGC CAGGCCTGCA TGGCTGCCAG 
CCGGGCTCCG TGTCTGTGGA TAAGAAGGGC TACATCTTTC TGACCCTTCG AGAAGTCAAC 
AAGGTGGTGA TCCTGGACCC GAAGGGGTCC CTCCTTGGAG ACTTCCTGAC AGCCTACCAC 
GGCCTGGAAA AGCCCCGGGT TACCACCATG GTGGATGGCA GGTACCTGGT CGTGTCCCTC 
AGTAACGGGA CCATCCACAT CTTTCGGGTC CGTTCTCCGG ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112223.1
CDS	256..2523
Translation	MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSGDRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS

Target ORF information:

RefSeq Version	NM_030961.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tripartite motif containing 56 (TRIM56), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030961.3

ORF Insert Sequence:

ATGGTTTCCC ACGGGTCCTC GCCCTCCCTC CTGGAGGCCC TGAGCAGCGA CTTCCTGGCC 
TGTAAAATCT GCCTGGAGCA GCTGCGGGCA CCCAAGACAC TGCCCTGCCT GCATACCTAC 
TGCCAAGACT GCCTGGCACA GCTGGCGGAT GGCGGCCGCG TCCGCTGCCC CGAGTGCCGC 
GAGACAGTGC CTGTGCCGCC CGAGGGTGTG GCCTCCTTCA AGACCAACTT CTTCGTCAAT 
GGGCTGCTGG ACCTGGTGAA GGCCCGGGCC TGTGGAGACC TGCGTGCCGG GAAGCCAGCC 
TGTGCCCTGT GTCCCCTGGT GGGTGGCACC AGCACCGGGG GGCCGGCCAC GGCCCGGTGC 
CTGGACTGTG CCGATGACTT GTGCCAGGCC TGTGCCGACG GGCACCGCTG CACCCGCCAG 
ACCCACACCC ACCGCGTGGT GGACCTGGTG GGCTACAGGG CCGGGTGGTA TGATGAGGAG 
GCCCGGGAGC GCCAAGCGGC CCAGTGTCCC CAGCACCCCG GGGAGGCACT GCGCTTCCTG 
TGCCAGCCCT GCTCACAGTT GCTGTGCAGA GAGTGCCGCC TAGACCCCCA CCTGGACCAC 
CCCTGCCTGC CTCTGGCTGA AGCTGTGCGT GCCCGGAGGC CGGGCCTGGA GGGACTGCTG 
GCCGGTGTGG ACAATAACCT GGTGGAGCTG GAGGCAGCGC GGAGGGTGGA GAAGGAGGCG 
CTAGCCCGGC TGCGGGAGCA GGCGGCCCGG GTGGGGACTC AGGTGGAGGA GGCGGCTGAG 
GGCGTCCTCC GGGCCCTGCT GGCCCAGAAG CAGGAGGTGC TGGGGCAGCT ACGAGCCCAC 
GTGGAGGCTG CCGAAGAAGC TGCTCGGGAG AGGCTGGCGG AGCTTGAGGG CCGGGAGCAG 
GTGGCCAGGG CCGCAGCCGC CTTCGCCCGC CGGGTACTCA GCCTGGGGCG AGAGGCCGAG 
ATCCTCTCCC TGGAAGGGGC GATCGCACAG CGGCTCAGGC AGCTGCAGGG CTGCCCCTGG 
GCACCAGGCC CGGCCCCCTG CCTGCTCCCA CAGCTGGAGC TCCATCCTGG GCTCCTGGAC 
AAGAACTGCC ACCTTCTTCG GCTGTCCTTT GAGGAGCAGC AGCCCCAGAA GGATGGTGGG 
AAAGACGGAG CTGGTACCCA GGGAGGTGAG GAGAGCCAGA GCCGGAGGGA GGATGAGCCG 
AAGACTGAGA GACAGGGTGG AGTCCAGCCC CAGGCTGGAG ATGGAGCCCA GACCCCAAAA 
GAGGAAAAAG CCCAGACAAC CCGAGAAGAG GGAGCCCAGA CCTTGGAGGA GGACAGGGCC 
CAGACACCCC ACGAGGATGG AGGACCCCAG CCCCACAGGG GTGGCAGACC CAACAAGAAG 
AAAAAGTTCA AAGGCAGGCT CAAGTCAATT TCCCGGGAGC CCAGCCCAGC CCTGGGGCCG 
AATCTGGACG GCTCTGGCCT CCTCCCCAGA CCCATCTTTT ACTGCAGTTT CCCCACGCGG 
ATGCCTGGAG ACAAGCGGTC CCCCCGGATC ACCGGGCTCT GTCCCTTCGG TCCCCGGGAG 
ATCCTGGTGG CGGATGAGCA GAACCGGGCA CTGAAACGCT TCTCCCTCAA CGGCGACTAC 
AAGGGCACCG TGCCGGTCCC TGAGGGCTGC TCCCCTTGCA GCGTGGCCGC CCTGCAGAGC 
GCGGTGGCCT TCTCCGCTAG CGCACGGCTC TATCTCATCA ACCCCAACGG CGAAGTGCAG 
TGGCGCAGGG CCCTGAGCCT CTCCCAGGCC AGCCACGCGG TGGCGGCACT GCCTAGCGGG 
GACCGCGTGG CTGTCAGCGT GGCGGGCCAC GTGGAGGTGT ACAATATGGA AGGCAGCCTG 
GCCACCCGGT TCATTCCTGG AGGCAAGGCC AGCCGGGGCC TGCGGGCGCT GGTGTTTCTG 
ACCACCAGCC CCCAGGGGCA TTTCGTGGGG TCGGACTGGC AGCAGAATAG TGTGGTAATC 
TGTGATGGGC TGGGCCAGGT GGTTGGGGAG TACAAGGGGC CAGGCCTGCA TGGCTGCCAG 
CCGGGCTCCG TGTCTGTGGA TAAGAAGGGC TACATCTTTC TGACCCTTCG AGAAGTCAAC 
AAGGTGGTGA TCCTGGACCC GAAGGGGTCC CTCCTTGGAG ACTTCCTGAC AGCCTACCAC 
GGCCTGGAAA AGCCCCGGGT TACCACCATG GTGGATGGCA GGTACCTGGT CGTGTCCCTC 
AGTAACGGGA CCATCCACAT CTTTCGGGTC CGTTCTCCGG ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIM56 ( NM_030961.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_112223.1 Homo sapiens tripartite motif containing 56 (TRIM56), mRNA.

Price & Availability↑

CloneID	OHu72997
Clone ID Related Accession (Same CDS sequence)	XM_011516589.3 , XM_011516589.2 , NM_030961.3 , NM_030961.2
Accession Version	NM_030961.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2268bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase TRIM56
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC005847.2, BC048194.1 and AC105446.4. On Dec 16, 2014 this sequence version replaced NM_030961.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC005847.2, BC048194.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGTTTCCC ACGGGTCCTC GCCCTCCCTC CTGGAGGCCC TGAGCAGCGA CTTCCTGGCC 
TGTAAAATCT GCCTGGAGCA GCTGCGGGCA CCCAAGACAC TGCCCTGCCT GCATACCTAC 
TGCCAAGACT GCCTGGCACA GCTGGCGGAT GGCGGCCGCG TCCGCTGCCC CGAGTGCCGC 
GAGACAGTGC CTGTGCCGCC CGAGGGTGTG GCCTCCTTCA AGACCAACTT CTTCGTCAAT 
GGGCTGCTGG ACCTGGTGAA GGCCCGGGCC TGTGGAGACC TGCGTGCCGG GAAGCCAGCC 
TGTGCCCTGT GTCCCCTGGT GGGTGGCACC AGCACCGGGG GGCCGGCCAC GGCCCGGTGC 
CTGGACTGTG CCGATGACTT GTGCCAGGCC TGTGCCGACG GGCACCGCTG CACCCGCCAG 
ACCCACACCC ACCGCGTGGT GGACCTGGTG GGCTACAGGG CCGGGTGGTA TGATGAGGAG 
GCCCGGGAGC GCCAAGCGGC CCAGTGTCCC CAGCACCCCG GGGAGGCACT GCGCTTCCTG 
TGCCAGCCCT GCTCACAGTT GCTGTGCAGA GAGTGCCGCC TAGACCCCCA CCTGGACCAC 
CCCTGCCTGC CTCTGGCTGA AGCTGTGCGT GCCCGGAGGC CGGGCCTGGA GGGACTGCTG 
GCCGGTGTGG ACAATAACCT GGTGGAGCTG GAGGCAGCGC GGAGGGTGGA GAAGGAGGCG 
CTAGCCCGGC TGCGGGAGCA GGCGGCCCGG GTGGGGACTC AGGTGGAGGA GGCGGCTGAG 
GGCGTCCTCC GGGCCCTGCT GGCCCAGAAG CAGGAGGTGC TGGGGCAGCT ACGAGCCCAC 
GTGGAGGCTG CCGAAGAAGC TGCTCGGGAG AGGCTGGCGG AGCTTGAGGG CCGGGAGCAG 
GTGGCCAGGG CCGCAGCCGC CTTCGCCCGC CGGGTACTCA GCCTGGGGCG AGAGGCCGAG 
ATCCTCTCCC TGGAAGGGGC GATCGCACAG CGGCTCAGGC AGCTGCAGGG CTGCCCCTGG 
GCACCAGGCC CGGCCCCCTG CCTGCTCCCA CAGCTGGAGC TCCATCCTGG GCTCCTGGAC 
AAGAACTGCC ACCTTCTTCG GCTGTCCTTT GAGGAGCAGC AGCCCCAGAA GGATGGTGGG 
AAAGACGGAG CTGGTACCCA GGGAGGTGAG GAGAGCCAGA GCCGGAGGGA GGATGAGCCG 
AAGACTGAGA GACAGGGTGG AGTCCAGCCC CAGGCTGGAG ATGGAGCCCA GACCCCAAAA 
GAGGAAAAAG CCCAGACAAC CCGAGAAGAG GGAGCCCAGA CCTTGGAGGA GGACAGGGCC 
CAGACACCCC ACGAGGATGG AGGACCCCAG CCCCACAGGG GTGGCAGACC CAACAAGAAG 
AAAAAGTTCA AAGGCAGGCT CAAGTCAATT TCCCGGGAGC CCAGCCCAGC CCTGGGGCCG 
AATCTGGACG GCTCTGGCCT CCTCCCCAGA CCCATCTTTT ACTGCAGTTT CCCCACGCGG 
ATGCCTGGAG ACAAGCGGTC CCCCCGGATC ACCGGGCTCT GTCCCTTCGG TCCCCGGGAG 
ATCCTGGTGG CGGATGAGCA GAACCGGGCA CTGAAACGCT TCTCCCTCAA CGGCGACTAC 
AAGGGCACCG TGCCGGTCCC TGAGGGCTGC TCCCCTTGCA GCGTGGCCGC CCTGCAGAGC 
GCGGTGGCCT TCTCCGCTAG CGCACGGCTC TATCTCATCA ACCCCAACGG CGAAGTGCAG 
TGGCGCAGGG CCCTGAGCCT CTCCCAGGCC AGCCACGCGG TGGCGGCACT GCCTAGCGGG 
GACCGCGTGG CTGTCAGCGT GGCGGGCCAC GTGGAGGTGT ACAATATGGA AGGCAGCCTG 
GCCACCCGGT TCATTCCTGG AGGCAAGGCC AGCCGGGGCC TGCGGGCGCT GGTGTTTCTG 
ACCACCAGCC CCCAGGGGCA TTTCGTGGGG TCGGACTGGC AGCAGAATAG TGTGGTAATC 
TGTGATGGGC TGGGCCAGGT GGTTGGGGAG TACAAGGGGC CAGGCCTGCA TGGCTGCCAG 
CCGGGCTCCG TGTCTGTGGA TAAGAAGGGC TACATCTTTC TGACCCTTCG AGAAGTCAAC 
AAGGTGGTGA TCCTGGACCC GAAGGGGTCC CTCCTTGGAG ACTTCCTGAC AGCCTACCAC 
GGCCTGGAAA AGCCCCGGGT TACCACCATG GTGGATGGCA GGTACCTGGT CGTGTCCCTC 
AGTAACGGGA CCATCCACAT CTTTCGGGTC CGTTCTCCGG ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112223.1
CDS	298..2565
Translation	MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSGDRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS

Target ORF information:

RefSeq Version	NM_030961.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tripartite motif containing 56 (TRIM56), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030961.2

ORF Insert Sequence:

ATGGTTTCCC ACGGGTCCTC GCCCTCCCTC CTGGAGGCCC TGAGCAGCGA CTTCCTGGCC 
TGTAAAATCT GCCTGGAGCA GCTGCGGGCA CCCAAGACAC TGCCCTGCCT GCATACCTAC 
TGCCAAGACT GCCTGGCACA GCTGGCGGAT GGCGGCCGCG TCCGCTGCCC CGAGTGCCGC 
GAGACAGTGC CTGTGCCGCC CGAGGGTGTG GCCTCCTTCA AGACCAACTT CTTCGTCAAT 
GGGCTGCTGG ACCTGGTGAA GGCCCGGGCC TGTGGAGACC TGCGTGCCGG GAAGCCAGCC 
TGTGCCCTGT GTCCCCTGGT GGGTGGCACC AGCACCGGGG GGCCGGCCAC GGCCCGGTGC 
CTGGACTGTG CCGATGACTT GTGCCAGGCC TGTGCCGACG GGCACCGCTG CACCCGCCAG 
ACCCACACCC ACCGCGTGGT GGACCTGGTG GGCTACAGGG CCGGGTGGTA TGATGAGGAG 
GCCCGGGAGC GCCAAGCGGC CCAGTGTCCC CAGCACCCCG GGGAGGCACT GCGCTTCCTG 
TGCCAGCCCT GCTCACAGTT GCTGTGCAGA GAGTGCCGCC TAGACCCCCA CCTGGACCAC 
CCCTGCCTGC CTCTGGCTGA AGCTGTGCGT GCCCGGAGGC CGGGCCTGGA GGGACTGCTG 
GCCGGTGTGG ACAATAACCT GGTGGAGCTG GAGGCAGCGC GGAGGGTGGA GAAGGAGGCG 
CTAGCCCGGC TGCGGGAGCA GGCGGCCCGG GTGGGGACTC AGGTGGAGGA GGCGGCTGAG 
GGCGTCCTCC GGGCCCTGCT GGCCCAGAAG CAGGAGGTGC TGGGGCAGCT ACGAGCCCAC 
GTGGAGGCTG CCGAAGAAGC TGCTCGGGAG AGGCTGGCGG AGCTTGAGGG CCGGGAGCAG 
GTGGCCAGGG CCGCAGCCGC CTTCGCCCGC CGGGTACTCA GCCTGGGGCG AGAGGCCGAG 
ATCCTCTCCC TGGAAGGGGC GATCGCACAG CGGCTCAGGC AGCTGCAGGG CTGCCCCTGG 
GCACCAGGCC CGGCCCCCTG CCTGCTCCCA CAGCTGGAGC TCCATCCTGG GCTCCTGGAC 
AAGAACTGCC ACCTTCTTCG GCTGTCCTTT GAGGAGCAGC AGCCCCAGAA GGATGGTGGG 
AAAGACGGAG CTGGTACCCA GGGAGGTGAG GAGAGCCAGA GCCGGAGGGA GGATGAGCCG 
AAGACTGAGA GACAGGGTGG AGTCCAGCCC CAGGCTGGAG ATGGAGCCCA GACCCCAAAA 
GAGGAAAAAG CCCAGACAAC CCGAGAAGAG GGAGCCCAGA CCTTGGAGGA GGACAGGGCC 
CAGACACCCC ACGAGGATGG AGGACCCCAG CCCCACAGGG GTGGCAGACC CAACAAGAAG 
AAAAAGTTCA AAGGCAGGCT CAAGTCAATT TCCCGGGAGC CCAGCCCAGC CCTGGGGCCG 
AATCTGGACG GCTCTGGCCT CCTCCCCAGA CCCATCTTTT ACTGCAGTTT CCCCACGCGG 
ATGCCTGGAG ACAAGCGGTC CCCCCGGATC ACCGGGCTCT GTCCCTTCGG TCCCCGGGAG 
ATCCTGGTGG CGGATGAGCA GAACCGGGCA CTGAAACGCT TCTCCCTCAA CGGCGACTAC 
AAGGGCACCG TGCCGGTCCC TGAGGGCTGC TCCCCTTGCA GCGTGGCCGC CCTGCAGAGC 
GCGGTGGCCT TCTCCGCTAG CGCACGGCTC TATCTCATCA ACCCCAACGG CGAAGTGCAG 
TGGCGCAGGG CCCTGAGCCT CTCCCAGGCC AGCCACGCGG TGGCGGCACT GCCTAGCGGG 
GACCGCGTGG CTGTCAGCGT GGCGGGCCAC GTGGAGGTGT ACAATATGGA AGGCAGCCTG 
GCCACCCGGT TCATTCCTGG AGGCAAGGCC AGCCGGGGCC TGCGGGCGCT GGTGTTTCTG 
ACCACCAGCC CCCAGGGGCA TTTCGTGGGG TCGGACTGGC AGCAGAATAG TGTGGTAATC 
TGTGATGGGC TGGGCCAGGT GGTTGGGGAG TACAAGGGGC CAGGCCTGCA TGGCTGCCAG 
CCGGGCTCCG TGTCTGTGGA TAAGAAGGGC TACATCTTTC TGACCCTTCG AGAAGTCAAC 
AAGGTGGTGA TCCTGGACCC GAAGGGGTCC CTCCTTGGAG ACTTCCTGAC AGCCTACCAC 
GGCCTGGAAA AGCCCCGGGT TACCACCATG GTGGATGGCA GGTACCTGGT CGTGTCCCTC 
AGTAACGGGA CCATCCACAT CTTTCGGGTC CGTTCTCCGG ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIM56 ( XM_011516589.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514891.1 Homo sapiens tripartite motif containing 56 (TRIM56), transcript variant X1, mRNA.

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CloneID	OHu72997
Clone ID Related Accession (Same CDS sequence)	XM_011516589.3 , XM_011516589.2 , NM_030961.3 , NM_030961.2
Accession Version	XM_011516589.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2268bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase TRIM56 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011516589.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTTCCC ACGGGTCCTC GCCCTCCCTC CTGGAGGCCC TGAGCAGCGA CTTCCTGGCC 
TGTAAAATCT GCCTGGAGCA GCTGCGGGCA CCCAAGACAC TGCCCTGCCT GCATACCTAC 
TGCCAAGACT GCCTGGCACA GCTGGCGGAT GGCGGCCGCG TCCGCTGCCC CGAGTGCCGC 
GAGACAGTGC CTGTGCCGCC CGAGGGTGTG GCCTCCTTCA AGACCAACTT CTTCGTCAAT 
GGGCTGCTGG ACCTGGTGAA GGCCCGGGCC TGTGGAGACC TGCGTGCCGG GAAGCCAGCC 
TGTGCCCTGT GTCCCCTGGT GGGTGGCACC AGCACCGGGG GGCCGGCCAC GGCCCGGTGC 
CTGGACTGTG CCGATGACTT GTGCCAGGCC TGTGCCGACG GGCACCGCTG CACCCGCCAG 
ACCCACACCC ACCGCGTGGT GGACCTGGTG GGCTACAGGG CCGGGTGGTA TGATGAGGAG 
GCCCGGGAGC GCCAAGCGGC CCAGTGTCCC CAGCACCCCG GGGAGGCACT GCGCTTCCTG 
TGCCAGCCCT GCTCACAGTT GCTGTGCAGA GAGTGCCGCC TAGACCCCCA CCTGGACCAC 
CCCTGCCTGC CTCTGGCTGA AGCTGTGCGT GCCCGGAGGC CGGGCCTGGA GGGACTGCTG 
GCCGGTGTGG ACAATAACCT GGTGGAGCTG GAGGCAGCGC GGAGGGTGGA GAAGGAGGCG 
CTAGCCCGGC TGCGGGAGCA GGCGGCCCGG GTGGGGACTC AGGTGGAGGA GGCGGCTGAG 
GGCGTCCTCC GGGCCCTGCT GGCCCAGAAG CAGGAGGTGC TGGGGCAGCT ACGAGCCCAC 
GTGGAGGCTG CCGAAGAAGC TGCTCGGGAG AGGCTGGCGG AGCTTGAGGG CCGGGAGCAG 
GTGGCCAGGG CCGCAGCCGC CTTCGCCCGC CGGGTACTCA GCCTGGGGCG AGAGGCCGAG 
ATCCTCTCCC TGGAAGGGGC GATCGCACAG CGGCTCAGGC AGCTGCAGGG CTGCCCCTGG 
GCACCAGGCC CGGCCCCCTG CCTGCTCCCA CAGCTGGAGC TCCATCCTGG GCTCCTGGAC 
AAGAACTGCC ACCTTCTTCG GCTGTCCTTT GAGGAGCAGC AGCCCCAGAA GGATGGTGGG 
AAAGACGGAG CTGGTACCCA GGGAGGTGAG GAGAGCCAGA GCCGGAGGGA GGATGAGCCG 
AAGACTGAGA GACAGGGTGG AGTCCAGCCC CAGGCTGGAG ATGGAGCCCA GACCCCAAAA 
GAGGAAAAAG CCCAGACAAC CCGAGAAGAG GGAGCCCAGA CCTTGGAGGA GGACAGGGCC 
CAGACACCCC ACGAGGATGG AGGACCCCAG CCCCACAGGG GTGGCAGACC CAACAAGAAG 
AAAAAGTTCA AAGGCAGGCT CAAGTCAATT TCCCGGGAGC CCAGCCCAGC CCTGGGGCCG 
AATCTGGACG GCTCTGGCCT CCTCCCCAGA CCCATCTTTT ACTGCAGTTT CCCCACGCGG 
ATGCCTGGAG ACAAGCGGTC CCCCCGGATC ACCGGGCTCT GTCCCTTCGG TCCCCGGGAG 
ATCCTGGTGG CGGATGAGCA GAACCGGGCA CTGAAACGCT TCTCCCTCAA CGGCGACTAC 
AAGGGCACCG TGCCGGTCCC TGAGGGCTGC TCCCCTTGCA GCGTGGCCGC CCTGCAGAGC 
GCGGTGGCCT TCTCCGCTAG CGCACGGCTC TATCTCATCA ACCCCAACGG CGAAGTGCAG 
TGGCGCAGGG CCCTGAGCCT CTCCCAGGCC AGCCACGCGG TGGCGGCACT GCCTAGCGGG 
GACCGCGTGG CTGTCAGCGT GGCGGGCCAC GTGGAGGTGT ACAATATGGA AGGCAGCCTG 
GCCACCCGGT TCATTCCTGG AGGCAAGGCC AGCCGGGGCC TGCGGGCGCT GGTGTTTCTG 
ACCACCAGCC CCCAGGGGCA TTTCGTGGGG TCGGACTGGC AGCAGAATAG TGTGGTAATC 
TGTGATGGGC TGGGCCAGGT GGTTGGGGAG TACAAGGGGC CAGGCCTGCA TGGCTGCCAG 
CCGGGCTCCG TGTCTGTGGA TAAGAAGGGC TACATCTTTC TGACCCTTCG AGAAGTCAAC 
AAGGTGGTGA TCCTGGACCC GAAGGGGTCC CTCCTTGGAG ACTTCCTGAC AGCCTACCAC 
GGCCTGGAAA AGCCCCGGGT TACCACCATG GTGGATGGCA GGTACCTGGT CGTGTCCCTC 
AGTAACGGGA CCATCCACAT CTTTCGGGTC CGTTCTCCGG ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514891.1
CDS	150..2417
Translation	MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSGDRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS

Target ORF information:

RefSeq Version	XM_011516589.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tripartite motif containing 56 (TRIM56), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516589.3

ORF Insert Sequence:

ATGGTTTCCC ACGGGTCCTC GCCCTCCCTC CTGGAGGCCC TGAGCAGCGA CTTCCTGGCC 
TGTAAAATCT GCCTGGAGCA GCTGCGGGCA CCCAAGACAC TGCCCTGCCT GCATACCTAC 
TGCCAAGACT GCCTGGCACA GCTGGCGGAT GGCGGCCGCG TCCGCTGCCC CGAGTGCCGC 
GAGACAGTGC CTGTGCCGCC CGAGGGTGTG GCCTCCTTCA AGACCAACTT CTTCGTCAAT 
GGGCTGCTGG ACCTGGTGAA GGCCCGGGCC TGTGGAGACC TGCGTGCCGG GAAGCCAGCC 
TGTGCCCTGT GTCCCCTGGT GGGTGGCACC AGCACCGGGG GGCCGGCCAC GGCCCGGTGC 
CTGGACTGTG CCGATGACTT GTGCCAGGCC TGTGCCGACG GGCACCGCTG CACCCGCCAG 
ACCCACACCC ACCGCGTGGT GGACCTGGTG GGCTACAGGG CCGGGTGGTA TGATGAGGAG 
GCCCGGGAGC GCCAAGCGGC CCAGTGTCCC CAGCACCCCG GGGAGGCACT GCGCTTCCTG 
TGCCAGCCCT GCTCACAGTT GCTGTGCAGA GAGTGCCGCC TAGACCCCCA CCTGGACCAC 
CCCTGCCTGC CTCTGGCTGA AGCTGTGCGT GCCCGGAGGC CGGGCCTGGA GGGACTGCTG 
GCCGGTGTGG ACAATAACCT GGTGGAGCTG GAGGCAGCGC GGAGGGTGGA GAAGGAGGCG 
CTAGCCCGGC TGCGGGAGCA GGCGGCCCGG GTGGGGACTC AGGTGGAGGA GGCGGCTGAG 
GGCGTCCTCC GGGCCCTGCT GGCCCAGAAG CAGGAGGTGC TGGGGCAGCT ACGAGCCCAC 
GTGGAGGCTG CCGAAGAAGC TGCTCGGGAG AGGCTGGCGG AGCTTGAGGG CCGGGAGCAG 
GTGGCCAGGG CCGCAGCCGC CTTCGCCCGC CGGGTACTCA GCCTGGGGCG AGAGGCCGAG 
ATCCTCTCCC TGGAAGGGGC GATCGCACAG CGGCTCAGGC AGCTGCAGGG CTGCCCCTGG 
GCACCAGGCC CGGCCCCCTG CCTGCTCCCA CAGCTGGAGC TCCATCCTGG GCTCCTGGAC 
AAGAACTGCC ACCTTCTTCG GCTGTCCTTT GAGGAGCAGC AGCCCCAGAA GGATGGTGGG 
AAAGACGGAG CTGGTACCCA GGGAGGTGAG GAGAGCCAGA GCCGGAGGGA GGATGAGCCG 
AAGACTGAGA GACAGGGTGG AGTCCAGCCC CAGGCTGGAG ATGGAGCCCA GACCCCAAAA 
GAGGAAAAAG CCCAGACAAC CCGAGAAGAG GGAGCCCAGA CCTTGGAGGA GGACAGGGCC 
CAGACACCCC ACGAGGATGG AGGACCCCAG CCCCACAGGG GTGGCAGACC CAACAAGAAG 
AAAAAGTTCA AAGGCAGGCT CAAGTCAATT TCCCGGGAGC CCAGCCCAGC CCTGGGGCCG 
AATCTGGACG GCTCTGGCCT CCTCCCCAGA CCCATCTTTT ACTGCAGTTT CCCCACGCGG 
ATGCCTGGAG ACAAGCGGTC CCCCCGGATC ACCGGGCTCT GTCCCTTCGG TCCCCGGGAG 
ATCCTGGTGG CGGATGAGCA GAACCGGGCA CTGAAACGCT TCTCCCTCAA CGGCGACTAC 
AAGGGCACCG TGCCGGTCCC TGAGGGCTGC TCCCCTTGCA GCGTGGCCGC CCTGCAGAGC 
GCGGTGGCCT TCTCCGCTAG CGCACGGCTC TATCTCATCA ACCCCAACGG CGAAGTGCAG 
TGGCGCAGGG CCCTGAGCCT CTCCCAGGCC AGCCACGCGG TGGCGGCACT GCCTAGCGGG 
GACCGCGTGG CTGTCAGCGT GGCGGGCCAC GTGGAGGTGT ACAATATGGA AGGCAGCCTG 
GCCACCCGGT TCATTCCTGG AGGCAAGGCC AGCCGGGGCC TGCGGGCGCT GGTGTTTCTG 
ACCACCAGCC CCCAGGGGCA TTTCGTGGGG TCGGACTGGC AGCAGAATAG TGTGGTAATC 
TGTGATGGGC TGGGCCAGGT GGTTGGGGAG TACAAGGGGC CAGGCCTGCA TGGCTGCCAG 
CCGGGCTCCG TGTCTGTGGA TAAGAAGGGC TACATCTTTC TGACCCTTCG AGAAGTCAAC 
AAGGTGGTGA TCCTGGACCC GAAGGGGTCC CTCCTTGGAG ACTTCCTGAC AGCCTACCAC 
GGCCTGGAAA AGCCCCGGGT TACCACCATG GTGGATGGCA GGTACCTGGT CGTGTCCCTC 
AGTAACGGGA CCATCCACAT CTTTCGGGTC CGTTCTCCGG ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRIM56 ( XM_011516589.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514891.1 Homo sapiens tripartite motif containing 56 (TRIM56), transcript variant X1, mRNA.

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CloneID	OHu72997
Clone ID Related Accession (Same CDS sequence)	XM_011516589.3 , XM_011516589.2 , NM_030961.3 , NM_030961.2
Accession Version	XM_011516589.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2268bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase TRIM56 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516589.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTTCCC ACGGGTCCTC GCCCTCCCTC CTGGAGGCCC TGAGCAGCGA CTTCCTGGCC 
TGTAAAATCT GCCTGGAGCA GCTGCGGGCA CCCAAGACAC TGCCCTGCCT GCATACCTAC 
TGCCAAGACT GCCTGGCACA GCTGGCGGAT GGCGGCCGCG TCCGCTGCCC CGAGTGCCGC 
GAGACAGTGC CTGTGCCGCC CGAGGGTGTG GCCTCCTTCA AGACCAACTT CTTCGTCAAT 
GGGCTGCTGG ACCTGGTGAA GGCCCGGGCC TGTGGAGACC TGCGTGCCGG GAAGCCAGCC 
TGTGCCCTGT GTCCCCTGGT GGGTGGCACC AGCACCGGGG GGCCGGCCAC GGCCCGGTGC 
CTGGACTGTG CCGATGACTT GTGCCAGGCC TGTGCCGACG GGCACCGCTG CACCCGCCAG 
ACCCACACCC ACCGCGTGGT GGACCTGGTG GGCTACAGGG CCGGGTGGTA TGATGAGGAG 
GCCCGGGAGC GCCAAGCGGC CCAGTGTCCC CAGCACCCCG GGGAGGCACT GCGCTTCCTG 
TGCCAGCCCT GCTCACAGTT GCTGTGCAGA GAGTGCCGCC TAGACCCCCA CCTGGACCAC 
CCCTGCCTGC CTCTGGCTGA AGCTGTGCGT GCCCGGAGGC CGGGCCTGGA GGGACTGCTG 
GCCGGTGTGG ACAATAACCT GGTGGAGCTG GAGGCAGCGC GGAGGGTGGA GAAGGAGGCG 
CTAGCCCGGC TGCGGGAGCA GGCGGCCCGG GTGGGGACTC AGGTGGAGGA GGCGGCTGAG 
GGCGTCCTCC GGGCCCTGCT GGCCCAGAAG CAGGAGGTGC TGGGGCAGCT ACGAGCCCAC 
GTGGAGGCTG CCGAAGAAGC TGCTCGGGAG AGGCTGGCGG AGCTTGAGGG CCGGGAGCAG 
GTGGCCAGGG CCGCAGCCGC CTTCGCCCGC CGGGTACTCA GCCTGGGGCG AGAGGCCGAG 
ATCCTCTCCC TGGAAGGGGC GATCGCACAG CGGCTCAGGC AGCTGCAGGG CTGCCCCTGG 
GCACCAGGCC CGGCCCCCTG CCTGCTCCCA CAGCTGGAGC TCCATCCTGG GCTCCTGGAC 
AAGAACTGCC ACCTTCTTCG GCTGTCCTTT GAGGAGCAGC AGCCCCAGAA GGATGGTGGG 
AAAGACGGAG CTGGTACCCA GGGAGGTGAG GAGAGCCAGA GCCGGAGGGA GGATGAGCCG 
AAGACTGAGA GACAGGGTGG AGTCCAGCCC CAGGCTGGAG ATGGAGCCCA GACCCCAAAA 
GAGGAAAAAG CCCAGACAAC CCGAGAAGAG GGAGCCCAGA CCTTGGAGGA GGACAGGGCC 
CAGACACCCC ACGAGGATGG AGGACCCCAG CCCCACAGGG GTGGCAGACC CAACAAGAAG 
AAAAAGTTCA AAGGCAGGCT CAAGTCAATT TCCCGGGAGC CCAGCCCAGC CCTGGGGCCG 
AATCTGGACG GCTCTGGCCT CCTCCCCAGA CCCATCTTTT ACTGCAGTTT CCCCACGCGG 
ATGCCTGGAG ACAAGCGGTC CCCCCGGATC ACCGGGCTCT GTCCCTTCGG TCCCCGGGAG 
ATCCTGGTGG CGGATGAGCA GAACCGGGCA CTGAAACGCT TCTCCCTCAA CGGCGACTAC 
AAGGGCACCG TGCCGGTCCC TGAGGGCTGC TCCCCTTGCA GCGTGGCCGC CCTGCAGAGC 
GCGGTGGCCT TCTCCGCTAG CGCACGGCTC TATCTCATCA ACCCCAACGG CGAAGTGCAG 
TGGCGCAGGG CCCTGAGCCT CTCCCAGGCC AGCCACGCGG TGGCGGCACT GCCTAGCGGG 
GACCGCGTGG CTGTCAGCGT GGCGGGCCAC GTGGAGGTGT ACAATATGGA AGGCAGCCTG 
GCCACCCGGT TCATTCCTGG AGGCAAGGCC AGCCGGGGCC TGCGGGCGCT GGTGTTTCTG 
ACCACCAGCC CCCAGGGGCA TTTCGTGGGG TCGGACTGGC AGCAGAATAG TGTGGTAATC 
TGTGATGGGC TGGGCCAGGT GGTTGGGGAG TACAAGGGGC CAGGCCTGCA TGGCTGCCAG 
CCGGGCTCCG TGTCTGTGGA TAAGAAGGGC TACATCTTTC TGACCCTTCG AGAAGTCAAC 
AAGGTGGTGA TCCTGGACCC GAAGGGGTCC CTCCTTGGAG ACTTCCTGAC AGCCTACCAC 
GGCCTGGAAA AGCCCCGGGT TACCACCATG GTGGATGGCA GGTACCTGGT CGTGTCCCTC 
AGTAACGGGA CCATCCACAT CTTTCGGGTC CGTTCTCCGG ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514891.1
CDS	150..2417
Translation	MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSGDRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS

Target ORF information:

RefSeq Version	XM_011516589.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tripartite motif containing 56 (TRIM56), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516589.2

ORF Insert Sequence:

ATGGTTTCCC ACGGGTCCTC GCCCTCCCTC CTGGAGGCCC TGAGCAGCGA CTTCCTGGCC 
TGTAAAATCT GCCTGGAGCA GCTGCGGGCA CCCAAGACAC TGCCCTGCCT GCATACCTAC 
TGCCAAGACT GCCTGGCACA GCTGGCGGAT GGCGGCCGCG TCCGCTGCCC CGAGTGCCGC 
GAGACAGTGC CTGTGCCGCC CGAGGGTGTG GCCTCCTTCA AGACCAACTT CTTCGTCAAT 
GGGCTGCTGG ACCTGGTGAA GGCCCGGGCC TGTGGAGACC TGCGTGCCGG GAAGCCAGCC 
TGTGCCCTGT GTCCCCTGGT GGGTGGCACC AGCACCGGGG GGCCGGCCAC GGCCCGGTGC 
CTGGACTGTG CCGATGACTT GTGCCAGGCC TGTGCCGACG GGCACCGCTG CACCCGCCAG 
ACCCACACCC ACCGCGTGGT GGACCTGGTG GGCTACAGGG CCGGGTGGTA TGATGAGGAG 
GCCCGGGAGC GCCAAGCGGC CCAGTGTCCC CAGCACCCCG GGGAGGCACT GCGCTTCCTG 
TGCCAGCCCT GCTCACAGTT GCTGTGCAGA GAGTGCCGCC TAGACCCCCA CCTGGACCAC 
CCCTGCCTGC CTCTGGCTGA AGCTGTGCGT GCCCGGAGGC CGGGCCTGGA GGGACTGCTG 
GCCGGTGTGG ACAATAACCT GGTGGAGCTG GAGGCAGCGC GGAGGGTGGA GAAGGAGGCG 
CTAGCCCGGC TGCGGGAGCA GGCGGCCCGG GTGGGGACTC AGGTGGAGGA GGCGGCTGAG 
GGCGTCCTCC GGGCCCTGCT GGCCCAGAAG CAGGAGGTGC TGGGGCAGCT ACGAGCCCAC 
GTGGAGGCTG CCGAAGAAGC TGCTCGGGAG AGGCTGGCGG AGCTTGAGGG CCGGGAGCAG 
GTGGCCAGGG CCGCAGCCGC CTTCGCCCGC CGGGTACTCA GCCTGGGGCG AGAGGCCGAG 
ATCCTCTCCC TGGAAGGGGC GATCGCACAG CGGCTCAGGC AGCTGCAGGG CTGCCCCTGG 
GCACCAGGCC CGGCCCCCTG CCTGCTCCCA CAGCTGGAGC TCCATCCTGG GCTCCTGGAC 
AAGAACTGCC ACCTTCTTCG GCTGTCCTTT GAGGAGCAGC AGCCCCAGAA GGATGGTGGG 
AAAGACGGAG CTGGTACCCA GGGAGGTGAG GAGAGCCAGA GCCGGAGGGA GGATGAGCCG 
AAGACTGAGA GACAGGGTGG AGTCCAGCCC CAGGCTGGAG ATGGAGCCCA GACCCCAAAA 
GAGGAAAAAG CCCAGACAAC CCGAGAAGAG GGAGCCCAGA CCTTGGAGGA GGACAGGGCC 
CAGACACCCC ACGAGGATGG AGGACCCCAG CCCCACAGGG GTGGCAGACC CAACAAGAAG 
AAAAAGTTCA AAGGCAGGCT CAAGTCAATT TCCCGGGAGC CCAGCCCAGC CCTGGGGCCG 
AATCTGGACG GCTCTGGCCT CCTCCCCAGA CCCATCTTTT ACTGCAGTTT CCCCACGCGG 
ATGCCTGGAG ACAAGCGGTC CCCCCGGATC ACCGGGCTCT GTCCCTTCGG TCCCCGGGAG 
ATCCTGGTGG CGGATGAGCA GAACCGGGCA CTGAAACGCT TCTCCCTCAA CGGCGACTAC 
AAGGGCACCG TGCCGGTCCC TGAGGGCTGC TCCCCTTGCA GCGTGGCCGC CCTGCAGAGC 
GCGGTGGCCT TCTCCGCTAG CGCACGGCTC TATCTCATCA ACCCCAACGG CGAAGTGCAG 
TGGCGCAGGG CCCTGAGCCT CTCCCAGGCC AGCCACGCGG TGGCGGCACT GCCTAGCGGG 
GACCGCGTGG CTGTCAGCGT GGCGGGCCAC GTGGAGGTGT ACAATATGGA AGGCAGCCTG 
GCCACCCGGT TCATTCCTGG AGGCAAGGCC AGCCGGGGCC TGCGGGCGCT GGTGTTTCTG 
ACCACCAGCC CCCAGGGGCA TTTCGTGGGG TCGGACTGGC AGCAGAATAG TGTGGTAATC 
TGTGATGGGC TGGGCCAGGT GGTTGGGGAG TACAAGGGGC CAGGCCTGCA TGGCTGCCAG 
CCGGGCTCCG TGTCTGTGGA TAAGAAGGGC TACATCTTTC TGACCCTTCG AGAAGTCAAC 
AAGGTGGTGA TCCTGGACCC GAAGGGGTCC CTCCTTGGAG ACTTCCTGAC AGCCTACCAC 
GGCCTGGAAA AGCCCCGGGT TACCACCATG GTGGATGGCA GGTACCTGGT CGTGTCCCTC 
AGTAACGGGA CCATCCACAT CTTTCGGGTC CGTTCTCCGG ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The ubiquitin ligase TRIM56 inhibits ovarian cancer progression by targeting vimentin.
Journal of cellular physiology233(3)2420-2425(2018 Mar)
Zhao L,Zhang P,Su XJ,Zhang B

TRIM56 Suppresses Multiple Myeloma Progression by Activating TLR3/TRIF Signaling.
Yonsei medical journal59(1)43-50(2018 Jan)
Chen Y,Zhao J,Li D,Hao J,He P,Wang H,Zhang M

Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA.
Nature communications814004(2017 Jan)
Fiskin E,Bhogaraju S,Herhaus L,Kalayil S,Hahn M,Dikic I

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TRIM56 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

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FAX

オンラインフォーム