BNIP3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BNIP3
Entrez Gene ID	664
Full Name	BCL2 interacting protein 3
Synonyms	NIP3
General protein information	Preferred Names BCL2 interacting protein 3 Names BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BCL2/adenovirus E1B 19kDa interacting protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q26.3
Summary	This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014].
Disorder MIM:	603293

mRNA and Protein(s)

mRNA	Protein	Name
NM_004052.3	NP_004043.3	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LOC607408	XP_849147.4
Pan troglodytes (chimpanzee)	BNIP3	XP_508116.2
Bos taurus (cattle)	BNIP3	NP_001069834.1
Rattus norvegicus (Norway rat)	Bnip3	NP_445872.1
Danio rerio (zebrafish)	bnip3	NP_001012245.1
Mus musculus (house mouse)	Bnip3	NP_033890.1
Gallus gallus (chicken)	BNIP3	XP_421829.3
Homo sapiens (human)	BNIP3	NP_004043.2
Xenopus tropicalis (tropical clawed frog)	bnip3	NP_001015859.1

Gene Ontology

The following BNIP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BNIP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu56510	NM_004052.3 Latest version!	Homo sapiens BCL2 interacting protein 3 (BNIP3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BNIP3 ( NM_004052.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004043.3 Homo sapiens BCL2 interacting protein 3 (BNIP3), mRNA.

Price & Availability↑

CloneID	OHu56510
Clone ID Related Accession (Same CDS sequence)	NM_004052.3
Accession Version	NM_004052.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Homo sapiens(human)
Product	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY049371.1, BC067818.1, AF002697.1 and BX647339.1. On Dec 19, 2014 this sequence version replaced NM_004052.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.420192.1, SRR1803613.284408.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267751 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCGACG CGGCCGCAGA TCCGCCCGGC CCCGCCCTGC CCTGTGAGTT CCTCCGGCCG 
GGCTGCGGGG CTCCGCTCAG TCCGGGAGCG CAGCTGGGCC GCGGCGCTCC GACCTCCGCT 
TTCCCACCGC CCGCAGCTGA AGCACATCCC GCAGCCCGGC GCGGACTCCG ATCGCCGCAG 
TTGCCCTCTG GCGCCATGTC GCAGAACGGA GCGCCCGGGA TGCAGGAGGA GAGCCTGCAG 
GGCTCCTGGG TAGAACTGCA CTTCAGCAAT AATGGGAACG GGGGCAGCGT TCCAGCCTCG 
GTTTCTATTT ATAATGGAGA CATGGAAAAA ATACTGCTGG ACGCACAGCA TGAGTCTGGA 
CGGAGTAGCT CCAAGAGCTC TCACTGTGAC AGCCCACCTC GCTCGCAGAC ACCACAAGAT 
ACCAACAGAG CTTCTGAAAC AGATACCCAT AGCATTGGAG AGAAAAACAG CTCACAGTCT 
GAGGAAGATG ATATTGAAAG AAGGAAAGAA GTTGAAAGCA TCTTGAAGAA AAACTCAGAT 
TGGATATGGG ATTGGTCAAG TCGGCCGGAA AATATTCCCC CCAAGGAGTT CCTCTTTAAA 
CACCCGAAGC GCACGGCCAC CCTCAGCATG AGGAACACGA GCGTCATGAA GAAAGGGGGC 
ATATTCTCTG CAGAATTTCT GAAAGTTTTC CTTCCATCTC TGCTGCTCTC TCATTTGCTG 
GCCATCGGAT TGGGGATCTA TATTGGAAGG CGTCTGACAA CCTCCACCAG CACCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004043.3
CDS	13..792
Translation	MGDAAADPPGPALPCEFLRPGCGAPLSPGAQLGRGAPTSAFPPPAAEAHPAARRGLRSPQLPSGAMSQNGAPGMQEESLQGSWVELHFSNNGNGGSVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRASETDTHSIGEKNSSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSAEFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF

Target ORF information:

RefSeq Version	NM_004052.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BCL2 interacting protein 3 (BNIP3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004052.3

ORF Insert Sequence:

ATGGGCGACG CGGCCGCAGA TCCGCCCGGC CCCGCCCTGC CCTGTGAGTT CCTCCGGCCG 
GGCTGCGGGG CTCCGCTCAG TCCGGGAGCG CAGCTGGGCC GCGGCGCTCC GACCTCCGCT 
TTCCCACCGC CCGCAGCTGA AGCACATCCC GCAGCCCGGC GCGGACTCCG ATCGCCGCAG 
TTGCCCTCTG GCGCCATGTC GCAGAACGGA GCGCCCGGGA TGCAGGAGGA GAGCCTGCAG 
GGCTCCTGGG TAGAACTGCA CTTCAGCAAT AATGGGAACG GGGGCAGCGT TCCAGCCTCG 
GTTTCTATTT ATAATGGAGA CATGGAAAAA ATACTGCTGG ACGCACAGCA TGAGTCTGGA 
CGGAGTAGCT CCAAGAGCTC TCACTGTGAC AGCCCACCTC GCTCGCAGAC ACCACAAGAT 
ACCAACAGAG CTTCTGAAAC AGATACCCAT AGCATTGGAG AGAAAAACAG CTCACAGTCT 
GAGGAAGATG ATATTGAAAG AAGGAAAGAA GTTGAAAGCA TCTTGAAGAA AAACTCAGAT 
TGGATATGGG ATTGGTCAAG TCGGCCGGAA AATATTCCCC CCAAGGAGTT CCTCTTTAAA 
CACCCGAAGC GCACGGCCAC CCTCAGCATG AGGAACACGA GCGTCATGAA GAAAGGGGGC 
ATATTCTCTG CAGAATTTCT GAAAGTTTTC CTTCCATCTC TGCTGCTCTC TCATTTGCTG 
GCCATCGGAT TGGGGATCTA TATTGGAAGG CGTCTGACAA CCTCCACCAG CACCTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.