DEFB109B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DEFB109B
Entrez Gene ID	641517
Full Name	defensin beta 109B
Synonyms	DEF109P1B,DEFB109,DEFB109P1B,HBD9
General protein information	Preferred Names defensin beta 109B Names putative beta-defensin 109B defensin beta 109 pseudogene 1B defensin, beta 9 pseudogene
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p23.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001037380.1	NP_001032457.1	putative beta-defensin 109B precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).
Dua HS, Otri AM, Hopkinson A, Mohammed I
Transactions of the American Ophthalmological Society11250-73(2014 Jul)

Cigarette smoke extract induces differential expression levels of beta-defensin peptides in human alveolar epithelial cells.
Pierson T, Learmonth-Pierson S, Pinto D, van Hoek ML
Tobacco induced diseases11(1)10(2013 Apr)

Variable expression of human Beta defensins 3 and 9 at the human ocular surface in infectious keratitis.
Otri AM, Mohammed I, Al-Aqaba MA, Fares U, Peng C, Hopkinson A, Dua HS
Investigative ophthalmology & visual science53(2)757-61(2012 Feb)

Localization and gene expression of human beta-defensin 9 at the human ocular surface epithelium.
Mohammed I, Suleman H, Otri AM, Kulkarni BB, Chen P, Hopkinson A, Dua HS
Investigative ophthalmology & visual science51(9)4677-82(2010 Sep)

Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms.
Alekseeva L, Huet D, F?m?nia F, Mouyna I, Abdelouahab M, Cagna A, Guerrier D, Tichann?-Seltzer V, Baeza-Squiban A, Chermette R, Latg? JP, Berkova N
BMC microbiology933(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DEFB109B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DEFB109B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu103222	NM_001037380.1 Latest version!	Homo sapiens defensin beta 109B (DEFB109B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DEFB109B ( NM_001037380.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001032457.1 Homo sapiens defensin beta 109B (DEFB109B), mRNA.

Price & Availability↑

CloneID	OHu103222
Clone ID Related Accession (Same CDS sequence)	NM_001037380.1
Accession Version	NM_001037380.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 264bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	putative beta-defensin 109B precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF228730.8. On Oct 6, 2017 this sequence version replaced XR_001756298.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: DQ012013.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAGACTCC ATTTGCTTCT CCTTATTCTC CTTCTTTTTT CAATTCTCTT ATCCCCAGTA 
AGAGGTGGTT TGGGTCCTGC GGAAGGTCAT TGTCTCAATT TGTTTGGTGT TTGCAGAACA 
GATGTCTGCA ACATAGTAGA AGATCAAATT GGTGCCTGCC GAAGAAGGAT GAAGTGCTGT 
AGAGCATGGT GGATTTTAAT GCCAATTCCA ACACCACTTA TCATGTCAGA TTATCAAGAA 
CCCCTTAAAC CTAACTTGAA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032457.1
CDS	1..264
Translation	MRLHLLLLILLLFSILLSPVRGGLGPAEGHCLNLFGVCRTDVCNIVEDQIGACRRRMKCCRAWWILMPIPTPLIMSDYQEPLKPNLK

Target ORF information:

RefSeq Version	NM_001037380.1
Organism	Homo sapiens(human)
Definition	Homo sapiens defensin beta 109B (DEFB109B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037380.1

ORF Insert Sequence:

ATGAGACTCC ATTTGCTTCT CCTTATTCTC CTTCTTTTTT CAATTCTCTT ATCCCCAGTA 
AGAGGTGGTT TGGGTCCTGC GGAAGGTCAT TGTCTCAATT TGTTTGGTGT TTGCAGAACA 
GATGTCTGCA ACATAGTAGA AGATCAAATT GGTGCCTGCC GAAGAAGGAT GAAGTGCTGT 
AGAGCATGGT GGATTTTAAT GCCAATTCCA ACACCACTTA TCATGTCAGA TTATCAAGAA 
CCCCTTAAAC CTAACTTGAA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).
Transactions of the American Ophthalmological Society11250-73(2014 Jul)
Dua HS,Otri AM,Hopkinson A,Mohammed I

Cigarette smoke extract induces differential expression levels of beta-defensin peptides in human alveolar epithelial cells.
Tobacco induced diseases11(1)10(2013 Apr)
Pierson T,Learmonth-Pierson S,Pinto D,van Hoek ML

Variable expression of human Beta defensins 3 and 9 at the human ocular surface in infectious keratitis.
Investigative ophthalmology & visual science53(2)757-61(2012 Feb)
Otri AM,Mohammed I,Al-Aqaba MA,Fares U,Peng C,Hopkinson A,Dua HS

Localization and gene expression of human beta-defensin 9 at the human ocular surface epithelium.
Investigative ophthalmology & visual science51(9)4677-82(2010 Sep)
Mohammed I,Suleman H,Otri AM,Kulkarni BB,Chen P,Hopkinson A,Dua HS

Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms.
BMC microbiology933(2009 Feb)
Alekseeva L,Huet D,F?m?nia F,Mouyna I,Abdelouahab M,Cagna A,Guerrier D,Tichann?-Seltzer V,Baeza-Squiban A,Chermette R,Latg? JP,Berkova N