ERMN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ERMN
Entrez Gene ID	57471
Full Name	ermin
Synonyms	JN,KIAA1189
General protein information	Preferred Names ermin Names ermin ermin, ERM-like protein juxtanodin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q24.1
Disorder MIM:	610072

mRNA and Protein(s)

mRNA	Protein	Name
NM_001304346.2	NP_001291275.1	ermin isoform c
NM_001304345.1	NP_001291274.1	ermin isoform b
NM_001009959.2	NP_001009959.1	ermin isoform a
NM_001304346.1	NP_001291275.1	ermin isoform c
NM_001009959.3	NP_001009959.1	ermin isoform a
NM_020711.3	NP_065762.1	ermin isoform b
NM_020711.2	NP_065762.1	ermin isoform b
NM_001304344.1	NP_001291273.1	ermin isoform b

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ERMN	NP_001230833.1
Bos taurus (cattle)	ERMN	NP_001029971.1
Mus musculus (house mouse)	Ermn	NP_084248.2
Homo sapiens (human)	ERMN	NP_001009959.1
	ERMN	XP_001088029.1
Canis lupus familiaris (dog)	ERMN	XP_849476.1
Rattus norvegicus (Norway rat)	Ermn	NP_001008312.1

Gene Ontology
Bibliography

Related articles in PubMed

Human Ermin (hErmin), a new oligodendrocyte-specific cytoskeletal protein related to epileptic seizure.
Wang T, Jia L, Lv B, Liu B, Wang W, Wang F, Yang G, Bu X, Yao L, Zhang B
Brain research136777-84(2011 Jan)

Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.
Dick DM, Meyers J, Aliev F, Nurnberger J Jr, Kramer J, Kuperman S, Porjesz B, Tischfield J, Edenberg HJ, Foroud T, Schuckit M, Goate A, Hesselbrock V, Bierut L
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics153B(6)1179-88(2010 Sep)

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Maccarrone G, Dias-Neto E, Turck CW
European archives of psychiatry and clinical neuroscience259(3)151-63(2009 Apr)

Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis.
Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Marangoni S, Novello JC, Maccarrone G, Turck CW, Dias-Neto E
Journal of neural transmission (Vienna, Austria : 1996)116(3)275-89(2009 Mar)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study suggested a role for hErmin as a novel cytoskeleton-related oligodendroglial protein in human brain myelination and human epileptogenesis, and provide new evidence for the relationship between oligodendrocytes and epilepsy.
Title: Human Ermin (hErmin), a new oligodendrocyte-specific cytoskeletal protein related to epileptic seizure.

Observational study of gene-disease association. (HuGE Navigator)
Title: Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.

Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
Title: Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.

This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia.
Title: Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis.

The following ERMN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERMN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03429	NM_020711.3 Latest version!	Homo sapiens ermin (ERMN), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu03429	NM_001304344.1 Latest version!	Homo sapiens ermin (ERMN), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu03429	NM_001304345.1 Latest version!	Homo sapiens ermin (ERMN), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu03935	NM_001009959.3 Latest version!	Homo sapiens ermin (ERMN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu70484	NM_001304346.2 Latest version!	Homo sapiens ermin (ERMN), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu70484	NM_001304346.1	Homo sapiens ermin (ERMN), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03935	NM_001009959.2	Homo sapiens ermin (ERMN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03429	NM_020711.2	Homo sapiens ermin (ERMN), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ERMN ( NM_001304345.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291274.1 Homo sapiens ermin (ERMN), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu03429
Clone ID Related Accession (Same CDS sequence)	NM_001304345.1 , NM_020711.3 , NM_020711.2 , NM_001304344.1
Accession Version	NM_001304345.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	ermin isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA248817.1, AB033015.1, DB576268.1 and AA736604.1. Transcript Variant: This variant (4) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode the same isoform (b). ##Evidence-Data-START## Transcript exon combination :: DA248817.1, SRR1803615.15784.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2154665 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAAACCCAG AAGAGAAACT CTTTATTGTT CATAAGGCTA TCACAGATCT TTCTCTCCAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291274.1
CDS	134..988
Translation	MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL

Target ORF information:

RefSeq Version	NM_001304345.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ermin (ERMN), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304345.1

ORF Insert Sequence:

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAAACCCAG AAGAGAAACT CTTTATTGTT CATAAGGCTA TCACAGATCT TTCTCTCCAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERMN ( NM_020711.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065762.1 Homo sapiens ermin (ERMN), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03429
Clone ID Related Accession (Same CDS sequence)	NM_001304345.1 , NM_020711.3 , NM_020711.2 , NM_001304344.1
Accession Version	NM_020711.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	ermin isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC343891.1, AB033015.1 and DB576268.1. On Jun 2, 2019 this sequence version replaced NM_020711.2. Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode the same isoform (b). ##Evidence-Data-START## Transcript exon combination :: SRR1803617.215049.1, SRR1803615.67765.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAAACCCAG AAGAGAAACT CTTTATTGTT CATAAGGCTA TCACAGATCT TTCTCTCCAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065762.1
CDS	183..1037
Translation	MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL

Target ORF information:

RefSeq Version	NM_020711.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ermin (ERMN), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020711.3

ORF Insert Sequence:

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAAACCCAG AAGAGAAACT CTTTATTGTT CATAAGGCTA TCACAGATCT TTCTCTCCAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERMN ( NM_020711.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_065762.1 Homo sapiens ermin (ERMN), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03429
Clone ID Related Accession (Same CDS sequence)	NM_001304345.1 , NM_020711.3 , NM_020711.2 , NM_001304344.1
Accession Version	NM_020711.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	ermin isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC331726.1, DC343891.1, AB033015.1, DB576268.1 and AA736604.1. On Jan 16, 2015 this sequence version replaced NM_020711.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode the same isoform (b). ##Evidence-Data-START## Transcript exon combination :: SRR1803611.237356.1, SRR1803617.251426.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAAACCCAG AAGAGAAACT CTTTATTGTT CATAAGGCTA TCACAGATCT TTCTCTCCAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065762.1
CDS	307..1161
Translation	MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL

Target ORF information:

RefSeq Version	NM_020711.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ermin (ERMN), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020711.2

ORF Insert Sequence:

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAAACCCAG AAGAGAAACT CTTTATTGTT CATAAGGCTA TCACAGATCT TTCTCTCCAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERMN ( NM_001304344.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291273.1 Homo sapiens ermin (ERMN), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu03429
Clone ID Related Accession (Same CDS sequence)	NM_001304345.1 , NM_020711.3 , NM_020711.2 , NM_001304344.1
Accession Version	NM_001304344.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	ermin isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA248817.1, DA288720.1, AB033015.1, DB576268.1 and AA736604.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode the same isoform (b). ##Evidence-Data-START## Transcript exon combination :: SRR1803615.112308.1, DA288720.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2154665 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAAACCCAG AAGAGAAACT CTTTATTGTT CATAAGGCTA TCACAGATCT TTCTCTCCAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291273.1
CDS	122..976
Translation	MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL

Target ORF information:

RefSeq Version	NM_001304344.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ermin (ERMN), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304344.1

ORF Insert Sequence:

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAAACCCAG AAGAGAAACT CTTTATTGTT CATAAGGCTA TCACAGATCT TTCTCTCCAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERMN ( NM_001009959.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001009959.1 Homo sapiens ermin (ERMN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu03935
Clone ID Related Accession (Same CDS sequence)	NM_001009959.2 , NM_001009959.3
Accession Version	NM_001009959.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	ermin isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC322056.1, AK296477.1, AB033015.1, DB576268.1 and AA736604.1. On Jan 16, 2015 this sequence version replaced NM_001009959.1. Transcript Variant: This variant (1) encodes the longest isoform (a). ##Evidence-Data-START## Transcript exon combination :: SRR1660807.124788.1, SRR1803617.15884.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGACTC TCTCTCCAGA TCGGATTCAA CCGCACATCA TGACAGATGT TCCGGCTACA 
TTTACCCAGG CTGAGTGTAA TGGGGATAAA CCACCTGAAA ACGGTCAACA AACAATCACT 
AAAATCAGTG AGGAATTGAC TGATGTGGAC AGCCCCCTGC CACACTACAG GGTAGAACCC 
AGTCTGGAAG GTGCACTCAC CAAAGGAAGT CAGGAGGAAA GAAGAAAATT ACAAGGGAAC 
ATGCTGCTCA ACTCATCCAT GGAGGACAAA ATGCTAAAAG AAAACCCAGA AGAGAAACTC 
TTTATTGTTC ATAAGGCTAT CACAGATCTT TCTCTCCAAG AAACTAGTGC TGATGAAATG 
ACATTCAGAG AAGGGCATCA GTGGGAGAAG ATTCCTCTGA GTGGCAGTAA CCAGGAAATA 
AGAAGACAGA AGGAGAGGAT TACTGAGCAG CCTCTCAAAG AGGAAGAAGA TGAGGACAGG 
AAGAACAAAG GTCACCAGGC AGCTGAAATT GAATGGCTGG GATTTCGAAA ACCTAGCCAA 
GCTGACATGT TACATTCTAA ACATGATGAG GAGCAGAAGG TTTGGGATGA AGAAATTGAT 
GATGATGATG ATGATAATTG CAATAATGAT GAAGATGAAG TTCGAGTGAT AGAATTTAAG 
AAAAAACATG AAGAGGTTTC TCAATTTAAA GAGGAAGGTG ATGCAAGTGA GGACTCCCCA 
CTGAGCAGTG CCAGTTCCCA AGCTGTGACA CCTGATGAGC AGCCAACCTT AGGGAAGAAG 
AGTGATATCT CCAGAAATGC TTATTCCAGA TACAATACAA TATCCTATCG GAAAATCAGA 
AAGGGAAATA CCAAGCAAAG AATTGATGAA TTCGAGTCTA TGATGCATTT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009959.1
CDS	235..1128
Translation	MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL

Target ORF information:

RefSeq Version	NM_001009959.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ermin (ERMN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009959.2

ORF Insert Sequence:

ATGAAGACTC TCTCTCCAGA TCGGATTCAA CCGCACATCA TGACAGATGT TCCGGCTACA 
TTTACCCAGG CTGAGTGTAA TGGGGATAAA CCACCTGAAA ACGGTCAACA AACAATCACT 
AAAATCAGTG AGGAATTGAC TGATGTGGAC AGCCCCCTGC CACACTACAG GGTAGAACCC 
AGTCTGGAAG GTGCACTCAC CAAAGGAAGT CAGGAGGAAA GAAGAAAATT ACAAGGGAAC 
ATGCTGCTCA ACTCATCCAT GGAGGACAAA ATGCTAAAAG AAAACCCAGA AGAGAAACTC 
TTTATTGTTC ATAAGGCTAT CACAGATCTT TCTCTCCAAG AAACTAGTGC TGATGAAATG 
ACATTCAGAG AAGGGCATCA GTGGGAGAAG ATTCCTCTGA GTGGCAGTAA CCAGGAAATA 
AGAAGACAGA AGGAGAGGAT TACTGAGCAG CCTCTCAAAG AGGAAGAAGA TGAGGACAGG 
AAGAACAAAG GTCACCAGGC AGCTGAAATT GAATGGCTGG GATTTCGAAA ACCTAGCCAA 
GCTGACATGT TACATTCTAA ACATGATGAG GAGCAGAAGG TTTGGGATGA AGAAATTGAT 
GATGATGATG ATGATAATTG CAATAATGAT GAAGATGAAG TTCGAGTGAT AGAATTTAAG 
AAAAAACATG AAGAGGTTTC TCAATTTAAA GAGGAAGGTG ATGCAAGTGA GGACTCCCCA 
CTGAGCAGTG CCAGTTCCCA AGCTGTGACA CCTGATGAGC AGCCAACCTT AGGGAAGAAG 
AGTGATATCT CCAGAAATGC TTATTCCAGA TACAATACAA TATCCTATCG GAAAATCAGA 
AAGGGAAATA CCAAGCAAAG AATTGATGAA TTCGAGTCTA TGATGCATTT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERMN ( NM_001009959.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001009959.1 Homo sapiens ermin (ERMN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu03935
Clone ID Related Accession (Same CDS sequence)	NM_001009959.2 , NM_001009959.3
Accession Version	NM_001009959.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	ermin isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC322056.1, AK296477.1, AB033015.1 and DB576268.1. On Jun 2, 2019 this sequence version replaced NM_001009959.2. Transcript Variant: This variant (1) encodes the longest isoform (a). ##Evidence-Data-START## Transcript exon combination :: SRR1660807.124788.1, SRR1803611.178301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGACTC TCTCTCCAGA TCGGATTCAA CCGCACATCA TGACAGATGT TCCGGCTACA 
TTTACCCAGG CTGAGTGTAA TGGGGATAAA CCACCTGAAA ACGGTCAACA AACAATCACT 
AAAATCAGTG AGGAATTGAC TGATGTGGAC AGCCCCCTGC CACACTACAG GGTAGAACCC 
AGTCTGGAAG GTGCACTCAC CAAAGGAAGT CAGGAGGAAA GAAGAAAATT ACAAGGGAAC 
ATGCTGCTCA ACTCATCCAT GGAGGACAAA ATGCTAAAAG AAAACCCAGA AGAGAAACTC 
TTTATTGTTC ATAAGGCTAT CACAGATCTT TCTCTCCAAG AAACTAGTGC TGATGAAATG 
ACATTCAGAG AAGGGCATCA GTGGGAGAAG ATTCCTCTGA GTGGCAGTAA CCAGGAAATA 
AGAAGACAGA AGGAGAGGAT TACTGAGCAG CCTCTCAAAG AGGAAGAAGA TGAGGACAGG 
AAGAACAAAG GTCACCAGGC AGCTGAAATT GAATGGCTGG GATTTCGAAA ACCTAGCCAA 
GCTGACATGT TACATTCTAA ACATGATGAG GAGCAGAAGG TTTGGGATGA AGAAATTGAT 
GATGATGATG ATGATAATTG CAATAATGAT GAAGATGAAG TTCGAGTGAT AGAATTTAAG 
AAAAAACATG AAGAGGTTTC TCAATTTAAA GAGGAAGGTG ATGCAAGTGA GGACTCCCCA 
CTGAGCAGTG CCAGTTCCCA AGCTGTGACA CCTGATGAGC AGCCAACCTT AGGGAAGAAG 
AGTGATATCT CCAGAAATGC TTATTCCAGA TACAATACAA TATCCTATCG GAAAATCAGA 
AAGGGAAATA CCAAGCAAAG AATTGATGAA TTCGAGTCTA TGATGCATTT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009959.1
CDS	234..1127
Translation	MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL

Target ORF information:

RefSeq Version	NM_001009959.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ermin (ERMN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009959.3

ORF Insert Sequence:

ATGAAGACTC TCTCTCCAGA TCGGATTCAA CCGCACATCA TGACAGATGT TCCGGCTACA 
TTTACCCAGG CTGAGTGTAA TGGGGATAAA CCACCTGAAA ACGGTCAACA AACAATCACT 
AAAATCAGTG AGGAATTGAC TGATGTGGAC AGCCCCCTGC CACACTACAG GGTAGAACCC 
AGTCTGGAAG GTGCACTCAC CAAAGGAAGT CAGGAGGAAA GAAGAAAATT ACAAGGGAAC 
ATGCTGCTCA ACTCATCCAT GGAGGACAAA ATGCTAAAAG AAAACCCAGA AGAGAAACTC 
TTTATTGTTC ATAAGGCTAT CACAGATCTT TCTCTCCAAG AAACTAGTGC TGATGAAATG 
ACATTCAGAG AAGGGCATCA GTGGGAGAAG ATTCCTCTGA GTGGCAGTAA CCAGGAAATA 
AGAAGACAGA AGGAGAGGAT TACTGAGCAG CCTCTCAAAG AGGAAGAAGA TGAGGACAGG 
AAGAACAAAG GTCACCAGGC AGCTGAAATT GAATGGCTGG GATTTCGAAA ACCTAGCCAA 
GCTGACATGT TACATTCTAA ACATGATGAG GAGCAGAAGG TTTGGGATGA AGAAATTGAT 
GATGATGATG ATGATAATTG CAATAATGAT GAAGATGAAG TTCGAGTGAT AGAATTTAAG 
AAAAAACATG AAGAGGTTTC TCAATTTAAA GAGGAAGGTG ATGCAAGTGA GGACTCCCCA 
CTGAGCAGTG CCAGTTCCCA AGCTGTGACA CCTGATGAGC AGCCAACCTT AGGGAAGAAG 
AGTGATATCT CCAGAAATGC TTATTCCAGA TACAATACAA TATCCTATCG GAAAATCAGA 
AAGGGAAATA CCAAGCAAAG AATTGATGAA TTCGAGTCTA TGATGCATTT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERMN ( NM_001304346.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291275.1 Homo sapiens ermin (ERMN), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu70484
Clone ID Related Accession (Same CDS sequence)	NM_001304346.2 , NM_001304346.1
Accession Version	NM_001304346.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	ermin isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK295844.1, AB033015.1 and DB576268.1. On Jun 2, 2019 this sequence version replaced NM_001304346.1. Transcript Variant: This variant (5) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (c) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: AK295844.1, DC335604.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291275.1
CDS	183..977
Translation	MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL

Target ORF information:

RefSeq Version	NM_001304346.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ermin (ERMN), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304346.2

ORF Insert Sequence:

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERMN ( NM_001304346.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291275.1 Homo sapiens ermin (ERMN), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu70484
Clone ID Related Accession (Same CDS sequence)	NM_001304346.2 , NM_001304346.1
Accession Version	NM_001304346.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	ermin isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC331726.1, DC343891.1, AK295844.1, AB033015.1, DB576268.1 and AA736604.1. Transcript Variant: This variant (5) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (c) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: AK295844.1, DC335604.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291275.1
CDS	307..1101
Translation	MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL

Target ORF information:

RefSeq Version	NM_001304346.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ermin (ERMN), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304346.1

ORF Insert Sequence:

ATGACAGATG TTCCGGCTAC ATTTACCCAG GCTGAGTGTA ATGGGGATAA ACCACCTGAA 
AACGGTCAAC AAACAATCAC TAAAATCAGT GAGGAATTGA CTGATGTGGA CAGCCCCCTG 
CCACACTACA GGGTAGAACC CAGTCTGGAA GGTGCACTCA CCAAAGGAAG TCAGGAGGAA 
AGAAGAAAAT TACAAGGGAA CATGCTGCTC AACTCATCCA TGGAGGACAA AATGCTAAAA 
GAAACTAGTG CTGATGAAAT GACATTCAGA GAAGGGCATC AGTGGGAGAA GATTCCTCTG 
AGTGGCAGTA ACCAGGAAAT AAGAAGACAG AAGGAGAGGA TTACTGAGCA GCCTCTCAAA 
GAGGAAGAAG ATGAGGACAG GAAGAACAAA GGTCACCAGG CAGCTGAAAT TGAATGGCTG 
GGATTTCGAA AACCTAGCCA AGCTGACATG TTACATTCTA AACATGATGA GGAGCAGAAG 
GTTTGGGATG AAGAAATTGA TGATGATGAT GATGATAATT GCAATAATGA TGAAGATGAA 
GTTCGAGTGA TAGAATTTAA GAAAAAACAT GAAGAGGTTT CTCAATTTAA AGAGGAAGGT 
GATGCAAGTG AGGACTCCCC ACTGAGCAGT GCCAGTTCCC AAGCTGTGAC ACCTGATGAG 
CAGCCAACCT TAGGGAAGAA GAGTGATATC TCCAGAAATG CTTATTCCAG ATACAATACA 
ATATCCTATC GGAAAATCAG AAAGGGAAAT ACCAAGCAAA GAATTGATGA ATTCGAGTCT 
ATGATGCATT TATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human Ermin (hErmin), a new oligodendrocyte-specific cytoskeletal protein related to epileptic seizure.
Brain research136777-84(2011 Jan)
Wang T,Jia L,Lv B,Liu B,Wang W,Wang F,Yang G,Bu X,Yao L,Zhang B

Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics153B(6)1179-88(2010 Sep)
Dick DM,Meyers J,Aliev F,Nurnberger J Jr,Kramer J,Kuperman S,Porjesz B,Tischfield J,Edenberg HJ,Foroud T,Schuckit M,Goate A,Hesselbrock V,Bierut L

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
European archives of psychiatry and clinical neuroscience259(3)151-63(2009 Apr)
Martins-de-Souza D,Gattaz WF,Schmitt A,Rewerts C,Maccarrone G,Dias-Neto E,Turck CW

Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis.
Journal of neural transmission (Vienna, Austria : 1996)116(3)275-89(2009 Mar)
Martins-de-Souza D,Gattaz WF,Schmitt A,Rewerts C,Marangoni S,Novello JC,Maccarrone G,Turck CW,Dias-Neto E

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

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ERMN cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

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