MRPL39 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MRPL39
Entrez Gene ID	54148
Full Name	mitochondrial ribosomal protein L39
Synonyms	C21orf92,L39mt,MRP-L5,MRPL5,MSTP003,PRED22,PRED66,RPML5
General protein information	Preferred Names mitochondrial ribosomal protein L39 Names 39S ribosomal protein L39, mitochondrial 39S ribosomal protein L5, mitochondrial L5mt MRP-L39 mitochondrial large ribosomal subunit protein mL39
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 21 Map Location: 21q21.3
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Jul 2008].
Disorder MIM:	611845

mRNA and Protein(s)

mRNA	Protein	Name
NM_080794.4	NP_542984.3	39S ribosomal protein L39, mitochondrial isoform b
XM_006724026.3	XP_006724089.1	39S ribosomal protein L39, mitochondrial isoform X2
XM_006724026.4	XP_006724089.1	39S ribosomal protein L39, mitochondrial isoform X2
NM_080794.3	NP_542984.2	39S ribosomal protein L39, mitochondrial isoform b
NM_017446.3	NP_059142.2	39S ribosomal protein L39, mitochondrial isoform a
NM_017446.4	NP_059142.3	39S ribosomal protein L39, mitochondrial isoform a
XM_011529651.2	XP_011527953.1	39S ribosomal protein L39, mitochondrial isoform X1

Pathways from BioSystems

Homologies

	MRPL39	XP_001105710.1
Xenopus tropicalis (tropical clawed frog)	mrpl39	NP_001011362.1
Pan troglodytes (chimpanzee)	MRPL39	XP_001158002.1
Canis lupus familiaris (dog)	MRPL39	XP_005638836.1
Drosophila melanogaster (fruit fly)	mRpL39	NP_524075.2
Mus musculus (house mouse)	Mrpl39	NP_059100.3
Rattus norvegicus (Norway rat)	Mrpl39	XP_006248076.1
Danio rerio (zebrafish)	mrpl39	NP_956209.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010644	XP_311362.3
Homo sapiens (human)	MRPL39	NP_542984.2
Bos taurus (cattle)	MRPL39	NP_001074199.1
Gallus gallus (chicken)	MRPL39	XP_416683.1

Gene Ontology
Bibliography

Related articles in PubMed

Structures of the human mitochondrial ribosome in native states of assembly.
Brown A, Rathore S, Kimanius D, Aibara S, Bai XC, Rorbach J, Amunts A, Ramakrishnan V
Nature structural & molecular biology24(10)866-869(2017 Oct)

Structure of the large ribosomal subunit from human mitochondria.
Brown A, Amunts A, Bai XC, Sugimoto Y, Edwards PC, Murshudov G, Scheres SHW, Ramakrishnan V
Science (New York, N.Y.)346(6210)718-722(2014 Nov)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following MRPL39 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MRPL39 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13490	NM_017446.3 Latest version!	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$144.50-$202.30 $289.00
OHu30940	NM_080794.3 Latest version!	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu53281	XM_006724026.4 Latest version!	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu68277	XM_011529651.2 Latest version!	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu108831	NM_017446.4 Latest version!	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu53281	NM_080794.4 Latest version!	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu53281	XM_006724026.3	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MRPL39 ( NM_017446.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_059142.2 Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13490
Clone ID Related Accession (Same CDS sequence)	NM_017446.3
Accession Version	NM_017446.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Homo sapiens(human)
Product	39S ribosomal protein L39, mitochondrial isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BQ719968.1, BC107719.1 and CD368044.1. On Jul 21, 2006 this sequence version replaced NM_017446.2. Transcript Variant: This variant (1) encodes the predominant isoform (a). ##Evidence-Data-START## Transcript exon combination :: SRR1163655.188997.1, SRR1163655.666368.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG CCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGG TAACTGAAGA TCAAAGTAAA GCAACAGAGG AATGTACATC TACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059142.2
CDS	15..1031
Translation	MEALAMGSRALRLWLVAPGGGIKWRFIATSPASQLSPTELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMVTEDQSKATEECTST

Target ORF information:

RefSeq Version	NM_017446.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017446.3

ORF Insert Sequence:

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG CCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGG TAACTGAAGA TCAAAGTAAA GCAACAGAGG AATGTACATC TACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MRPL39 ( NM_080794.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_542984.2 Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30940
Clone ID Related Accession (Same CDS sequence)	NM_080794.3
Accession Version	NM_080794.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Homo sapiens(human)
Product	39S ribosomal protein L39, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BQ719968.1, BC107719.1, CD368044.1 and AF270511.1. On Jul 21, 2006 this sequence version replaced NM_080794.2. Transcript Variant: This variant (2), also known as MRP-L5V1 or the heart-specific transcript variant, includes an alternate segment, when compared to variant 1, that causes a frameshift. The encoded isoform (b) has a distinct and longer C-terminus, compared to isoform a. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG CCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGA CTCCATTTCC CATTCTCCTT CTATTTACTA CGCAGTCATT CTTCACTACC 
TCGCCTGAGT CGTACCTCCT CCATGGAACA GTCTCAGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542984.2
CDS	15..1076
Translation	MEALAMGSRALRLWLVAPGGGIKWRFIATSPASQLSPTELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMTPFPILLLFTTQSFFTTSPESYLLHGTVSE

Target ORF information:

RefSeq Version	NM_080794.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080794.3

ORF Insert Sequence:

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG CCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGA CTCCATTTCC CATTCTCCTT CTATTTACTA CGCAGTCATT CTTCACTACC 
TCGCCTGAGT CGTACCTCCT CCATGGAACA GTCTCAGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MRPL39 ( XM_006724026.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006724089.1 Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu53281
Clone ID Related Accession (Same CDS sequence)	NM_080794.4 , XM_006724026.3 , XM_006724026.4
Accession Version	XM_006724026.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	39S ribosomal protein L39, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006724026.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG TCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGA CTCCATTTCC CATTCTCCTT CTATTTACTA CGCAGTCATT CTTCACTACC 
TCGCCTGAGT CGTACCTCCT CCATGGAACA GTCTCAGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006724089.1
CDS	7..1068
Translation	MEALAMGSRALRLWLVAPGGGIKWRFIATSSASQLSPTELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMTPFPILLLFTTQSFFTTSPESYLLHGTVSE

Target ORF information:

RefSeq Version	XM_006724026.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006724026.3

ORF Insert Sequence:

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG TCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGA CTCCATTTCC CATTCTCCTT CTATTTACTA CGCAGTCATT CTTCACTACC 
TCGCCTGAGT CGTACCTCCT CCATGGAACA GTCTCAGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MRPL39 ( XM_006724026.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006724089.1 Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu53281
Clone ID Related Accession (Same CDS sequence)	NM_080794.4 , XM_006724026.3 , XM_006724026.4
Accession Version	XM_006724026.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	39S ribosomal protein L39, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006724026.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG TCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGA CTCCATTTCC CATTCTCCTT CTATTTACTA CGCAGTCATT CTTCACTACC 
TCGCCTGAGT CGTACCTCCT CCATGGAACA GTCTCAGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006724089.1
CDS	7..1068
Translation	MEALAMGSRALRLWLVAPGGGIKWRFIATSSASQLSPTELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMTPFPILLLFTTQSFFTTSPESYLLHGTVSE

Target ORF information:

RefSeq Version	XM_006724026.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006724026.4

ORF Insert Sequence:

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG TCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGA CTCCATTTCC CATTCTCCTT CTATTTACTA CGCAGTCATT CTTCACTACC 
TCGCCTGAGT CGTACCTCCT CCATGGAACA GTCTCAGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MRPL39 ( XM_011529651.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011527953.1 Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X1, mRNA.

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CloneID	OHu68277
Clone ID Related Accession (Same CDS sequence)	XM_011529651.2
Accession Version	XM_011529651.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	39S ribosomal protein L39, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529651.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGAATG ATCTCTTTAA TAAAGAGAAA GCCAGGCAGT TATCATTAAC TCCCCGAACT 
GAGAAGATAG AAGTTAAGCA TGTTGGGAAA ACTGACCCCG GTACTGTCTT CGTGATGAAT 
AAAAACATTT CAACTCCCTA CAGTTGTGCC ATGCATTTAA GCGAGTGGTA TTGCAGGAAG 
TCCATTCTGG CTCTGGTGGA TGGACAGCCT TGGGACATGT ATAAGCCTTT AACAAAGTCC 
TGTGAAATTA AATTTCTTAC TTTCAAAGAT TGTGATCCAG GAGAAGTGAA TAAGGCATAT 
TGGCGTTCCT GTGCTATGAT GATGGGCTGT GTGATAGAGA GGGCATTCAA AGATGAATAT 
ATGGTCAATT TGGTCAGAGC TCCAGAAGTT CCTGTAATTT CTGGTGCCTT CTGTTATGAC 
GTAGTTTTGG ATAGCAAACT TGATGAGTGG ATGCCAACAA AAGAGAACTT ACGTTCCTTC 
ACAAAAGATG CTCATGCTTT AATTTATAAA GATCTTCCAT TTGAAACTCT GGAAGTTGAA 
GCAAAAGTGG CATTGGAAAT ATTTCAACAC AGCAAGTACA AAGTAGATTT CATAGAAGAG 
AAGGCATCTC AGAACCCTGA GAGAATAGTC AAGCTACACA GAATAGGTGA CTTCATTGAT 
GTGAGTGAGG GCCCTCTTAT TCCAAGAACA AGTATTTGTT TCCAGTATGA AGTATCAGCA 
GTTCACAATC TTCAACCCAC CCAGCCAAGT CTCATACGAA GATTCCAGGG CGTGTCTTTA 
CCTGTTCACT TAAGAGCACA TTTTACAATA TGGGATAAGC TATTGGAAAG ATCTCGGAAA 
ATGGTAACTG AAGATCAAAG TAAAGCAACA GAGGAATGTA CATCTACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011527953.1
CDS	212..1102
Translation	MRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMVTEDQSKATEECTST

Target ORF information:

RefSeq Version	XM_011529651.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529651.2

ORF Insert Sequence:

ATGCGGAATG ATCTCTTTAA TAAAGAGAAA GCCAGGCAGT TATCATTAAC TCCCCGAACT 
GAGAAGATAG AAGTTAAGCA TGTTGGGAAA ACTGACCCCG GTACTGTCTT CGTGATGAAT 
AAAAACATTT CAACTCCCTA CAGTTGTGCC ATGCATTTAA GCGAGTGGTA TTGCAGGAAG 
TCCATTCTGG CTCTGGTGGA TGGACAGCCT TGGGACATGT ATAAGCCTTT AACAAAGTCC 
TGTGAAATTA AATTTCTTAC TTTCAAAGAT TGTGATCCAG GAGAAGTGAA TAAGGCATAT 
TGGCGTTCCT GTGCTATGAT GATGGGCTGT GTGATAGAGA GGGCATTCAA AGATGAATAT 
ATGGTCAATT TGGTCAGAGC TCCAGAAGTT CCTGTAATTT CTGGTGCCTT CTGTTATGAC 
GTAGTTTTGG ATAGCAAACT TGATGAGTGG ATGCCAACAA AAGAGAACTT ACGTTCCTTC 
ACAAAAGATG CTCATGCTTT AATTTATAAA GATCTTCCAT TTGAAACTCT GGAAGTTGAA 
GCAAAAGTGG CATTGGAAAT ATTTCAACAC AGCAAGTACA AAGTAGATTT CATAGAAGAG 
AAGGCATCTC AGAACCCTGA GAGAATAGTC AAGCTACACA GAATAGGTGA CTTCATTGAT 
GTGAGTGAGG GCCCTCTTAT TCCAAGAACA AGTATTTGTT TCCAGTATGA AGTATCAGCA 
GTTCACAATC TTCAACCCAC CCAGCCAAGT CTCATACGAA GATTCCAGGG CGTGTCTTTA 
CCTGTTCACT TAAGAGCACA TTTTACAATA TGGGATAAGC TATTGGAAAG ATCTCGGAAA 
ATGGTAACTG AAGATCAAAG TAAAGCAACA GAGGAATGTA CATCTACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MRPL39 ( NM_017446.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_059142.3 Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 1, mRNA.

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CloneID	OHu108831
Clone ID Related Accession (Same CDS sequence)	NM_017446.4
Accession Version	NM_017446.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	39S ribosomal protein L39, mitochondrial isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000223.1. On Aug 6, 2019 this sequence version replaced NM_017446.3. Transcript Variant: This variant (1) encodes the predominant isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC107719.1, SRR7346977.16798.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG TCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGG TAACTGAAGA TCAAAGTAAA GCAACAGAGG AATGTACATC TACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059142.3
CDS	7..1023
Translation	MEALAMGSRALRLWLVAPGGGIKWRFIATSSASQLSPTELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMVTEDQSKATEECTST

Target ORF information:

RefSeq Version	NM_017446.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017446.4

ORF Insert Sequence:

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG TCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGG TAACTGAAGA TCAAAGTAAA GCAACAGAGG AATGTACATC TACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MRPL39 ( NM_080794.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_542984.3 Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 2, mRNA.

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CloneID	OHu53281
Clone ID Related Accession (Same CDS sequence)	NM_080794.4 , XM_006724026.3 , XM_006724026.4
Accession Version	NM_080794.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	39S ribosomal protein L39, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000223.1. On Aug 6, 2019 this sequence version replaced NM_080794.3. Transcript Variant: This variant (2), also known as MRP-L5V1 or the heart-specific transcript variant, includes an alternate segment, when compared to variant 1, that causes a frameshift. The encoded isoform (b) has a distinct and longer C-terminus, compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG TCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGA CTCCATTTCC CATTCTCCTT CTATTTACTA CGCAGTCATT CTTCACTACC 
TCGCCTGAGT CGTACCTCCT CCATGGAACA GTCTCAGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542984.3
CDS	7..1068
Translation	MEALAMGSRALRLWLVAPGGGIKWRFIATSSASQLSPTELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMTPFPILLLFTTQSFFTTSPESYLLHGTVSE

Target ORF information:

RefSeq Version	NM_080794.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mitochondrial ribosomal protein L39 (MRPL39), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080794.4

ORF Insert Sequence:

ATGGAGGCGC TGGCCATGGG TTCCCGGGCG CTGCGGCTCT GGCTGGTCGC ACCCGGTGGC 
GGGATCAAAT GGAGATTTAT AGCAACATCG TCAGCTTCTC AGCTGTCACC GACAGAATTG 
ACAGAAATGC GGAATGATCT CTTTAATAAA GAGAAAGCCA GGCAGTTATC ATTAACTCCC 
CGAACTGAGA AGATAGAAGT TAAGCATGTT GGGAAAACTG ACCCCGGTAC TGTCTTCGTG 
ATGAATAAAA ACATTTCAAC TCCCTACAGT TGTGCCATGC ATTTAAGCGA GTGGTATTGC 
AGGAAGTCCA TTCTGGCTCT GGTGGATGGA CAGCCTTGGG ACATGTATAA GCCTTTAACA 
AAGTCCTGTG AAATTAAATT TCTTACTTTC AAAGATTGTG ATCCAGGAGA AGTGAATAAG 
GCATATTGGC GTTCCTGTGC TATGATGATG GGCTGTGTGA TAGAGAGGGC ATTCAAAGAT 
GAATATATGG TCAATTTGGT CAGAGCTCCA GAAGTTCCTG TAATTTCTGG TGCCTTCTGT 
TATGACGTAG TTTTGGATAG CAAACTTGAT GAGTGGATGC CAACAAAAGA GAACTTACGT 
TCCTTCACAA AAGATGCTCA TGCTTTAATT TATAAAGATC TTCCATTTGA AACTCTGGAA 
GTTGAAGCAA AAGTGGCATT GGAAATATTT CAACACAGCA AGTACAAAGT AGATTTCATA 
GAAGAGAAGG CATCTCAGAA CCCTGAGAGA ATAGTCAAGC TACACAGAAT AGGTGACTTC 
ATTGATGTGA GTGAGGGCCC TCTTATTCCA AGAACAAGTA TTTGTTTCCA GTATGAAGTA 
TCAGCAGTTC ACAATCTTCA ACCCACCCAG CCAAGTCTCA TACGAAGATT CCAGGGCGTG 
TCTTTACCTG TTCACTTAAG AGCACATTTT ACAATATGGG ATAAGCTATT GGAAAGATCT 
CGGAAAATGA CTCCATTTCC CATTCTCCTT CTATTTACTA CGCAGTCATT CTTCACTACC 
TCGCCTGAGT CGTACCTCCT CCATGGAACA GTCTCAGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structures of the human mitochondrial ribosome in native states of assembly.
Nature structural & molecular biology24(10)866-869(2017 Oct)
Brown A,Rathore S,Kimanius D,Aibara S,Bai XC,Rorbach J,Amunts A,Ramakrishnan V

Structure of the large ribosomal subunit from human mitochondria.
Science (New York, N.Y.)346(6210)718-722(2014 Nov)
Brown A,Amunts A,Bai XC,Sugimoto Y,Edwards PC,Murshudov G,Scheres SHW,Ramakrishnan V

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

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MRPL39 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

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