MS4A4A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MS4A4A
Entrez Gene ID	51338
Full Name	membrane spanning 4-domains A4A
Synonyms	4SPAN1,CD20-L1,CD20L1,HDCME31P,MS4A4,MS4A7
General protein information	Preferred Names membrane spanning 4-domains A4A Names membrane-spanning 4-domains subfamily A member 4A CD20 antigen-like 1 Fc epsilon receptor beta subunit homolog four-span transmembrane protein 1 membrane-spanning 4-domains, subfamily A, member 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q12.2
Summary	This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features, similar intron/exon splice boundaries, and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
Disorder MIM:	606547

mRNA and Protein(s)

mRNA	Protein	Name
XM_017017909.1	XP_016873398.1	membrane-spanning 4-domains subfamily A member 4A isoform X1
NM_001243266.2	NP_001230195.1	membrane-spanning 4-domains subfamily A member 4A isoform 3
NM_148975.3	NP_683876.1	membrane-spanning 4-domains subfamily A member 4A isoform 1
NM_024021.4	NP_076926.2	membrane-spanning 4-domains subfamily A member 4A isoform 2
NM_001243266.1	NP_001230195.1	membrane-spanning 4-domains subfamily A member 4A isoform 3
NM_024021.3	NP_076926.2	membrane-spanning 4-domains subfamily A member 4A isoform 2
NM_148975.2	NP_683876.1	membrane-spanning 4-domains subfamily A member 4A isoform 1
XM_017017909.2	XP_016873398.1	membrane-spanning 4-domains subfamily A member 4A isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MS4A4A	XP_001138329.1
Mus musculus (house mouse)	Ms4a4a	XP_992035.2
Homo sapiens (human)	MS4A4A	NP_683876.1
	MS4A4A	XP_001086681.2
Canis lupus familiaris (dog)	LOC476900	XP_534104.4

Gene Ontology
Bibliography

Related articles in PubMed

MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells.
Sanyal R, Polyak MJ, Zuccolo J, Puri M, Deng L, Roberts L, Zuba A, Storek J, Luider JM, Sundberg EM, Mansoor A, Baigorri E, Chu MP, Belch AR, Pilarski LM, Deans JP
Immunology and cell biology95(7)611-619(2017 Aug)

Human gingiva transcriptome during wound healing.
Wang Y, Tatakis DN
Journal of clinical periodontology44(4)394-402(2017 Apr)

The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling.
Cruse G, Beaven MA, Music SC, Bradding P, Gilfillan AM, Metcalfe DD
Molecular biology of the cell26(9)1711-27(2015 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MS4A4A expression is significantly upregulated in human masticatory mucosa during wound healing
Title: Human gingiva transcriptome during wound healing.

MS4A4 in human mast cells effects ligand-induced KIT endocytosis pathways and reduced receptor recycling to the cell surface, thus promoting KIT signaling in the endosomes while reducing that in the plasma membrane.
Title: The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling.

Single nucleotide polymorphisms in APOE-epsilon4, CLU and MS4A4A influence both Alzheimer disease risk and cerebrospinal fluid Amyloid-beta1-42 levels.
Title: Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Title: Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

The following MS4A4A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MS4A4A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55862	NM_001243266.1 Latest version!	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu55911	NM_148975.2 Latest version!	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu55975	NM_024021.3 Latest version!	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu107841	NM_148975.3 Latest version!	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu108164	NM_001243266.2 Latest version!	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu92309	NM_024021.4 Latest version!	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu92309	XM_017017909.2 Latest version!	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu92309	XM_017017909.1	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MS4A4A ( NM_001243266.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001230195.1 Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu55862
Clone ID Related Accession (Same CDS sequence)	NM_001243266.1
Accession Version	NM_001243266.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-08
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 4A isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG538851.1, CB046393.1, BC020648.1 and AF237912.1. Transcript Variant: This variant (3) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (3) missing an internal protein segment compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.358203.1, CB046393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCATCAGA CCTACAGCAG ACATTGCAGG CCTGAAGAAA GCACCTTTTC TGCTGCCATG 
ACAACCATGC AAGGAATGGA ACAGGCCATG CCAGGGGCTG GCCCTGGTGT GCCCCAGCTG 
GGAAACATGG CTGTCATACA TTCACATCTG TGGAAAGGAT TGCAAGAGAA GTTCTTGAAG 
GGAGAACCCA AAGTCCTTGG GGTTGTGCAG ATTCTGACTG CCCTGATGAG CCTTAGCATG 
GGAATAACAA TGATGTGTAT GGCATCTAAT ACTTATGGAA GTAACCCTAT TTCCGTGTAT 
ATCGGGTACA CAATTTGGGG GTCAGTAATG TTTATTATTT CAGGATCCTT GTCAATTGCA 
GCAGGAATTA GAACTACAAA AGGCCTGGGT CTGGATGGCA TGGTGCTCCT CTTAAGTGTG 
CTGGAATTCT GCATTGCTGT GTCCCTCTCT GCCTTTGGAT GTAAAGTGCT CTGTTGTACC 
CCTGGTGGGG TTGTGTTAAT TCTGCCATCA CATTCTCACA TGGCAGAAAC AGCATCTCCC 
ACACCACTTA ATGAGGTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001230195.1
CDS	136..696
Translation	MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV

Target ORF information:

RefSeq Version	NM_001243266.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001243266.1

ORF Insert Sequence:

ATGCATCAGA CCTACAGCAG ACATTGCAGG CCTGAAGAAA GCACCTTTTC TGCTGCCATG 
ACAACCATGC AAGGAATGGA ACAGGCCATG CCAGGGGCTG GCCCTGGTGT GCCCCAGCTG 
GGAAACATGG CTGTCATACA TTCACATCTG TGGAAAGGAT TGCAAGAGAA GTTCTTGAAG 
GGAGAACCCA AAGTCCTTGG GGTTGTGCAG ATTCTGACTG CCCTGATGAG CCTTAGCATG 
GGAATAACAA TGATGTGTAT GGCATCTAAT ACTTATGGAA GTAACCCTAT TTCCGTGTAT 
ATCGGGTACA CAATTTGGGG GTCAGTAATG TTTATTATTT CAGGATCCTT GTCAATTGCA 
GCAGGAATTA GAACTACAAA AGGCCTGGGT CTGGATGGCA TGGTGCTCCT CTTAAGTGTG 
CTGGAATTCT GCATTGCTGT GTCCCTCTCT GCCTTTGGAT GTAAAGTGCT CTGTTGTACC 
CCTGGTGGGG TTGTGTTAAT TCTGCCATCA CATTCTCACA TGGCAGAAAC AGCATCTCCC 
ACACCACTTA ATGAGGTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A4A ( NM_148975.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_683876.1 Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55911
Clone ID Related Accession (Same CDS sequence)	NM_148975.2
Accession Version	NM_148975.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 4A isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG538851.1, BC020648.1 and AF237912.1. On Aug 6, 2011 this sequence version replaced NM_148975.1. Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803614.73161.1, SRR1660805.164202.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCATCAGA CCTACAGCAG ACATTGCAGG CCTGAAGAAA GCACCTTTTC TGCTGCCATG 
ACAACCATGC AAGGAATGGA ACAGGCCATG CCAGGGGCTG GCCCTGGTGT GCCCCAGCTG 
GGAAACATGG CTGTCATACA TTCACATCTG TGGAAAGGAT TGCAAGAGAA GTTCTTGAAG 
GGAGAACCCA AAGTCCTTGG GGTTGTGCAG ATTCTGACTG CCCTGATGAG CCTTAGCATG 
GGAATAACAA TGATGTGTAT GGCATCTAAT ACTTATGGAA GTAACCCTAT TTCCGTGTAT 
ATCGGGTACA CAATTTGGGG GTCAGTAATG TTTATTATTT CAGGATCCTT GTCAATTGCA 
GCAGGAATTA GAACTACAAA AGGCCTGGTC CGAGGTAGTC TAGGAATGAA TATCACCAGC 
TCTGTACTGG CTGCATCAGG GATCTTAATC AACACATTTA GCTTGGCGTT TTATTCATTC 
CATCACCCTT ACTGTAACTA CTATGGCAAC TCAAATAATT GTCATGGGAC TATGTCCATC 
TTAATGGGTC TGGATGGCAT GGTGCTCCTC TTAAGTGTGC TGGAATTCTG CATTGCTGTG 
TCCCTCTCTG CCTTTGGATG TAAAGTGCTC TGTTGTACCC CTGGTGGGGT TGTGTTAATT 
CTGCCATCAC ATTCTCACAT GGCAGAAACA GCATCTCCCA CACCACTTAA TGAGGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683876.1
CDS	136..855
Translation	MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV

Target ORF information:

RefSeq Version	NM_148975.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148975.2

ORF Insert Sequence:

ATGCATCAGA CCTACAGCAG ACATTGCAGG CCTGAAGAAA GCACCTTTTC TGCTGCCATG 
ACAACCATGC AAGGAATGGA ACAGGCCATG CCAGGGGCTG GCCCTGGTGT GCCCCAGCTG 
GGAAACATGG CTGTCATACA TTCACATCTG TGGAAAGGAT TGCAAGAGAA GTTCTTGAAG 
GGAGAACCCA AAGTCCTTGG GGTTGTGCAG ATTCTGACTG CCCTGATGAG CCTTAGCATG 
GGAATAACAA TGATGTGTAT GGCATCTAAT ACTTATGGAA GTAACCCTAT TTCCGTGTAT 
ATCGGGTACA CAATTTGGGG GTCAGTAATG TTTATTATTT CAGGATCCTT GTCAATTGCA 
GCAGGAATTA GAACTACAAA AGGCCTGGTC CGAGGTAGTC TAGGAATGAA TATCACCAGC 
TCTGTACTGG CTGCATCAGG GATCTTAATC AACACATTTA GCTTGGCGTT TTATTCATTC 
CATCACCCTT ACTGTAACTA CTATGGCAAC TCAAATAATT GTCATGGGAC TATGTCCATC 
TTAATGGGTC TGGATGGCAT GGTGCTCCTC TTAAGTGTGC TGGAATTCTG CATTGCTGTG 
TCCCTCTCTG CCTTTGGATG TAAAGTGCTC TGTTGTACCC CTGGTGGGGT TGTGTTAATT 
CTGCCATCAC ATTCTCACAT GGCAGAAACA GCATCTCCCA CACCACTTAA TGAGGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A4A ( NM_024021.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_076926.2 Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu55975
Clone ID Related Accession (Same CDS sequence)	NM_024021.3
Accession Version	NM_024021.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-08
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 4A isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG538851.1, AK075081.1, BC020648.1 and AF237912.1. On Aug 6, 2011 this sequence version replaced NM_024021.2. Transcript Variant: This variant (2) contains an additional exon at the 5' end compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (2) with a shorter N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK075081.1, SRR1803614.255632.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAACCA TGCAAGGAAT GGAACAGGCC ATGCCAGGGG CTGGCCCTGG TGTGCCCCAG 
CTGGGAAACA TGGCTGTCAT ACATTCACAT CTGTGGAAAG GATTGCAAGA GAAGTTCTTG 
AAGGGAGAAC CCAAAGTCCT TGGGGTTGTG CAGATTCTGA CTGCCCTGAT GAGCCTTAGC 
ATGGGAATAA CAATGATGTG TATGGCATCT AATACTTATG GAAGTAACCC TATTTCCGTG 
TATATCGGGT ACACAATTTG GGGGTCAGTA ATGTTTATTA TTTCAGGATC CTTGTCAATT 
GCAGCAGGAA TTAGAACTAC AAAAGGCCTG GTCCGAGGTA GTCTAGGAAT GAATATCACC 
AGCTCTGTAC TGGCTGCATC AGGGATCTTA ATCAACACAT TTAGCTTGGC GTTTTATTCA 
TTCCATCACC CTTACTGTAA CTACTATGGC AACTCAAATA ATTGTCATGG GACTATGTCC 
ATCTTAATGG GTCTGGATGG CATGGTGCTC CTCTTAAGTG TGCTGGAATT CTGCATTGCT 
GTGTCCCTCT CTGCCTTTGG ATGTAAAGTG CTCTGTTGTA CCCCTGGTGG GGTTGTGTTA 
ATTCTGCCAT CACATTCTCA CATGGCAGAA ACAGCATCTC CCACACCACT TAATGAGGTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076926.2
CDS	339..1001
Translation	MTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV

Target ORF information:

RefSeq Version	NM_024021.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024021.3

ORF Insert Sequence:

ATGACAACCA TGCAAGGAAT GGAACAGGCC ATGCCAGGGG CTGGCCCTGG TGTGCCCCAG 
CTGGGAAACA TGGCTGTCAT ACATTCACAT CTGTGGAAAG GATTGCAAGA GAAGTTCTTG 
AAGGGAGAAC CCAAAGTCCT TGGGGTTGTG CAGATTCTGA CTGCCCTGAT GAGCCTTAGC 
ATGGGAATAA CAATGATGTG TATGGCATCT AATACTTATG GAAGTAACCC TATTTCCGTG 
TATATCGGGT ACACAATTTG GGGGTCAGTA ATGTTTATTA TTTCAGGATC CTTGTCAATT 
GCAGCAGGAA TTAGAACTAC AAAAGGCCTG GTCCGAGGTA GTCTAGGAAT GAATATCACC 
AGCTCTGTAC TGGCTGCATC AGGGATCTTA ATCAACACAT TTAGCTTGGC GTTTTATTCA 
TTCCATCACC CTTACTGTAA CTACTATGGC AACTCAAATA ATTGTCATGG GACTATGTCC 
ATCTTAATGG GTCTGGATGG CATGGTGCTC CTCTTAAGTG TGCTGGAATT CTGCATTGCT 
GTGTCCCTCT CTGCCTTTGG ATGTAAAGTG CTCTGTTGTA CCCCTGGTGG GGTTGTGTTA 
ATTCTGCCAT CACATTCTCA CATGGCAGAA ACAGCATCTC CCACACCACT TAATGAGGTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A4A ( NM_148975.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_683876.1 Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu107841
Clone ID Related Accession (Same CDS sequence)	NM_148975.3
Accession Version	NM_148975.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 4A isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003970.3 and AP003127.2. On Nov 23, 2018 this sequence version replaced NM_148975.2. Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC020648.1, SRR5189655.122554.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000337908.5/ ENSP00000338648.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCATCAGA CCTACAGCAG ACATTGCAGG CCTGAAGAAA GCACCTTTTC TGCTGCCATG 
ACAACCATGC AAGGAATGGA ACAGGCCATG CCAGGGGCTG GCCCTGGTGT GCCCCAGCTG 
GGAAACATGG CTGTCATACA TTCACATCTG TGGAAAGGAT TGCAAGAGAA GTTCTTGAAG 
GGAGAACCCA AAGTCCTTGG GGTTGTGCAG ATTCTGACTG CCCTGATGAG CCTTAGCATG 
GGAATAACAA TGATGTGTAT GGCATCTAAT ACTTATGGAA GTAACCCTAT TTCCGTGTAT 
ATCGGGTACA CAATTTGGGG GTCAGTAATG TTTATTATTT CAGGATCCTT GTCAATTGCA 
GCAGGAATTA GAACTACAAA AGGCCTGGTC CGAGGTAGTC TAGGAATGAA TATCACCAGC 
TCTGTACTGG CTGCATCAGG GATCTTAATC AACACATTTA GCTTGGCGTT TTATTCATTC 
CATCACCCTT ACTGTAACTA CTATGGCAAC TCAAATAATT GTCATGGGAC TATGTCCATC 
TTAATGGGTC TGGATGGCAT GGTGCTCCTC CTAAGTGTGC TGGAATTCTG CATTGCTGTG 
TCCCTCTCTG CCTTTGGATG TAAAGTGCTC TGTTGTACCC CTGGTGGGGT TGTGTTAATT 
CTGCCATCAC ATTCTCACAT GGCAGAAACA GCATCTCCCA CACCACTTAA TGAGGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683876.1
CDS	11..730
Translation	MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV

Target ORF information:

RefSeq Version	NM_148975.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148975.3

ORF Insert Sequence:

ATGCATCAGA CCTACAGCAG ACATTGCAGG CCTGAAGAAA GCACCTTTTC TGCTGCCATG 
ACAACCATGC AAGGAATGGA ACAGGCCATG CCAGGGGCTG GCCCTGGTGT GCCCCAGCTG 
GGAAACATGG CTGTCATACA TTCACATCTG TGGAAAGGAT TGCAAGAGAA GTTCTTGAAG 
GGAGAACCCA AAGTCCTTGG GGTTGTGCAG ATTCTGACTG CCCTGATGAG CCTTAGCATG 
GGAATAACAA TGATGTGTAT GGCATCTAAT ACTTATGGAA GTAACCCTAT TTCCGTGTAT 
ATCGGGTACA CAATTTGGGG GTCAGTAATG TTTATTATTT CAGGATCCTT GTCAATTGCA 
GCAGGAATTA GAACTACAAA AGGCCTGGTC CGAGGTAGTC TAGGAATGAA TATCACCAGC 
TCTGTACTGG CTGCATCAGG GATCTTAATC AACACATTTA GCTTGGCGTT TTATTCATTC 
CATCACCCTT ACTGTAACTA CTATGGCAAC TCAAATAATT GTCATGGGAC TATGTCCATC 
TTAATGGGTC TGGATGGCAT GGTGCTCCTC CTAAGTGTGC TGGAATTCTG CATTGCTGTG 
TCCCTCTCTG CCTTTGGATG TAAAGTGCTC TGTTGTACCC CTGGTGGGGT TGTGTTAATT 
CTGCCATCAC ATTCTCACAT GGCAGAAACA GCATCTCCCA CACCACTTAA TGAGGTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A4A ( NM_001243266.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001230195.1 Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 3, mRNA.

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CloneID	OHu108164
Clone ID Related Accession (Same CDS sequence)	NM_001243266.2
Accession Version	NM_001243266.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 4A isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003970.3 and AP003127.2. On May 31, 2019 this sequence version replaced NM_001243266.1. Transcript Variant: This variant (3) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (3) missing an internal protein segment compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.358203.1, CB046393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCATCAGA CCTACAGCAG ACATTGCAGG CCTGAAGAAA GCACCTTTTC TGCTGCCATG 
ACAACCATGC AAGGAATGGA ACAGGCCATG CCAGGGGCTG GCCCTGGTGT GCCCCAGCTG 
GGAAACATGG CTGTCATACA TTCACATCTG TGGAAAGGAT TGCAAGAGAA GTTCTTGAAG 
GGAGAACCCA AAGTCCTTGG GGTTGTGCAG ATTCTGACTG CCCTGATGAG CCTTAGCATG 
GGAATAACAA TGATGTGTAT GGCATCTAAT ACTTATGGAA GTAACCCTAT TTCCGTGTAT 
ATCGGGTACA CAATTTGGGG GTCAGTAATG TTTATTATTT CAGGATCCTT GTCAATTGCA 
GCAGGAATTA GAACTACAAA AGGCCTGGGT CTGGATGGCA TGGTGCTCCT CCTAAGTGTG 
CTGGAATTCT GCATTGCTGT GTCCCTCTCT GCCTTTGGAT GTAAAGTGCT CTGTTGTACC 
CCTGGTGGGG TTGTGTTAAT TCTGCCATCA CATTCTCACA TGGCAGAAAC AGCATCTCCC 
ACACCACTTA ATGAGGTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001230195.1
CDS	11..571
Translation	MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV

Target ORF information:

RefSeq Version	NM_001243266.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001243266.2

ORF Insert Sequence:

ATGCATCAGA CCTACAGCAG ACATTGCAGG CCTGAAGAAA GCACCTTTTC TGCTGCCATG 
ACAACCATGC AAGGAATGGA ACAGGCCATG CCAGGGGCTG GCCCTGGTGT GCCCCAGCTG 
GGAAACATGG CTGTCATACA TTCACATCTG TGGAAAGGAT TGCAAGAGAA GTTCTTGAAG 
GGAGAACCCA AAGTCCTTGG GGTTGTGCAG ATTCTGACTG CCCTGATGAG CCTTAGCATG 
GGAATAACAA TGATGTGTAT GGCATCTAAT ACTTATGGAA GTAACCCTAT TTCCGTGTAT 
ATCGGGTACA CAATTTGGGG GTCAGTAATG TTTATTATTT CAGGATCCTT GTCAATTGCA 
GCAGGAATTA GAACTACAAA AGGCCTGGGT CTGGATGGCA TGGTGCTCCT CCTAAGTGTG 
CTGGAATTCT GCATTGCTGT GTCCCTCTCT GCCTTTGGAT GTAAAGTGCT CTGTTGTACC 
CCTGGTGGGG TTGTGTTAAT TCTGCCATCA CATTCTCACA TGGCAGAAAC AGCATCTCCC 
ACACCACTTA ATGAGGTTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A4A ( NM_024021.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_076926.2 Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 2, mRNA.

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CloneID	OHu92309
Clone ID Related Accession (Same CDS sequence)	XM_017017909.1 , NM_024021.4 , XM_017017909.2
Accession Version	NM_024021.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 4A isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003970.3 and AP003127.2. On Jun 1, 2019 this sequence version replaced NM_024021.3. Transcript Variant: This variant (2) contains an additional exon at the 5' end compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (2) with a shorter N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.255632.1, AK075081.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAACCA TGCAAGGAAT GGAACAGGCC ATGCCAGGGG CTGGCCCTGG TGTGCCCCAG 
CTGGGAAACA TGGCTGTCAT ACATTCACAT CTGTGGAAAG GATTGCAAGA GAAGTTCTTG 
AAGGGAGAAC CCAAAGTCCT TGGGGTTGTG CAGATTCTGA CTGCCCTGAT GAGCCTTAGC 
ATGGGAATAA CAATGATGTG TATGGCATCT AATACTTATG GAAGTAACCC TATTTCCGTG 
TATATCGGGT ACACAATTTG GGGGTCAGTA ATGTTTATTA TTTCAGGATC CTTGTCAATT 
GCAGCAGGAA TTAGAACTAC AAAAGGCCTG GTCCGAGGTA GTCTAGGAAT GAATATCACC 
AGCTCTGTAC TGGCTGCATC AGGGATCTTA ATCAACACAT TTAGCTTGGC GTTTTATTCA 
TTCCATCACC CTTACTGTAA CTACTATGGC AACTCAAATA ATTGTCATGG GACTATGTCC 
ATCTTAATGG GTCTGGATGG CATGGTGCTC CTCCTAAGTG TGCTGGAATT CTGCATTGCT 
GTGTCCCTCT CTGCCTTTGG ATGTAAAGTG CTCTGTTGTA CCCCTGGTGG GGTTGTGTTA 
ATTCTGCCAT CACATTCTCA CATGGCAGAA ACAGCATCTC CCACACCACT TAATGAGGTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076926.2
CDS	214..876
Translation	MTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV

Target ORF information:

RefSeq Version	NM_024021.4
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024021.4

ORF Insert Sequence:

ATGACAACCA TGCAAGGAAT GGAACAGGCC ATGCCAGGGG CTGGCCCTGG TGTGCCCCAG 
CTGGGAAACA TGGCTGTCAT ACATTCACAT CTGTGGAAAG GATTGCAAGA GAAGTTCTTG 
AAGGGAGAAC CCAAAGTCCT TGGGGTTGTG CAGATTCTGA CTGCCCTGAT GAGCCTTAGC 
ATGGGAATAA CAATGATGTG TATGGCATCT AATACTTATG GAAGTAACCC TATTTCCGTG 
TATATCGGGT ACACAATTTG GGGGTCAGTA ATGTTTATTA TTTCAGGATC CTTGTCAATT 
GCAGCAGGAA TTAGAACTAC AAAAGGCCTG GTCCGAGGTA GTCTAGGAAT GAATATCACC 
AGCTCTGTAC TGGCTGCATC AGGGATCTTA ATCAACACAT TTAGCTTGGC GTTTTATTCA 
TTCCATCACC CTTACTGTAA CTACTATGGC AACTCAAATA ATTGTCATGG GACTATGTCC 
ATCTTAATGG GTCTGGATGG CATGGTGCTC CTCCTAAGTG TGCTGGAATT CTGCATTGCT 
GTGTCCCTCT CTGCCTTTGG ATGTAAAGTG CTCTGTTGTA CCCCTGGTGG GGTTGTGTTA 
ATTCTGCCAT CACATTCTCA CATGGCAGAA ACAGCATCTC CCACACCACT TAATGAGGTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A4A ( XM_017017909.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873398.1 Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu92309
Clone ID Related Accession (Same CDS sequence)	XM_017017909.1 , NM_024021.4 , XM_017017909.2
Accession Version	XM_017017909.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 4A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAACCA TGCAAGGAAT GGAACAGGCC ATGCCAGGGG CTGGCCCTGG TGTGCCCCAG 
CTGGGAAACA TGGCTGTCAT ACATTCACAT CTGTGGAAAG GATTGCAAGA GAAGTTCTTG 
AAGGGAGAAC CCAAAGTCCT TGGGGTTGTG CAGATTCTGA CTGCCCTGAT GAGCCTTAGC 
ATGGGAATAA CAATGATGTG TATGGCATCT AATACTTATG GAAGTAACCC TATTTCCGTG 
TATATCGGGT ACACAATTTG GGGGTCAGTA ATGTTTATTA TTTCAGGATC CTTGTCAATT 
GCAGCAGGAA TTAGAACTAC AAAAGGCCTG GTCCGAGGTA GTCTAGGAAT GAATATCACC 
AGCTCTGTAC TGGCTGCATC AGGGATCTTA ATCAACACAT TTAGCTTGGC GTTTTATTCA 
TTCCATCACC CTTACTGTAA CTACTATGGC AACTCAAATA ATTGTCATGG GACTATGTCC 
ATCTTAATGG GTCTGGATGG CATGGTGCTC CTCCTAAGTG TGCTGGAATT CTGCATTGCT 
GTGTCCCTCT CTGCCTTTGG ATGTAAAGTG CTCTGTTGTA CCCCTGGTGG GGTTGTGTTA 
ATTCTGCCAT CACATTCTCA CATGGCAGAA ACAGCATCTC CCACACCACT TAATGAGGTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873398.1
CDS	206..868
Translation	MTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV

Target ORF information:

RefSeq Version	XM_017017909.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017909.1

ORF Insert Sequence:

ATGACAACCA TGCAAGGAAT GGAACAGGCC ATGCCAGGGG CTGGCCCTGG TGTGCCCCAG 
CTGGGAAACA TGGCTGTCAT ACATTCACAT CTGTGGAAAG GATTGCAAGA GAAGTTCTTG 
AAGGGAGAAC CCAAAGTCCT TGGGGTTGTG CAGATTCTGA CTGCCCTGAT GAGCCTTAGC 
ATGGGAATAA CAATGATGTG TATGGCATCT AATACTTATG GAAGTAACCC TATTTCCGTG 
TATATCGGGT ACACAATTTG GGGGTCAGTA ATGTTTATTA TTTCAGGATC CTTGTCAATT 
GCAGCAGGAA TTAGAACTAC AAAAGGCCTG GTCCGAGGTA GTCTAGGAAT GAATATCACC 
AGCTCTGTAC TGGCTGCATC AGGGATCTTA ATCAACACAT TTAGCTTGGC GTTTTATTCA 
TTCCATCACC CTTACTGTAA CTACTATGGC AACTCAAATA ATTGTCATGG GACTATGTCC 
ATCTTAATGG GTCTGGATGG CATGGTGCTC CTCCTAAGTG TGCTGGAATT CTGCATTGCT 
GTGTCCCTCT CTGCCTTTGG ATGTAAAGTG CTCTGTTGTA CCCCTGGTGG GGTTGTGTTA 
ATTCTGCCAT CACATTCTCA CATGGCAGAA ACAGCATCTC CCACACCACT TAATGAGGTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A4A ( XM_017017909.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016873398.1 Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu92309
Clone ID Related Accession (Same CDS sequence)	XM_017017909.1 , NM_024021.4 , XM_017017909.2
Accession Version	XM_017017909.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 4A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017017909.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAACCA TGCAAGGAAT GGAACAGGCC ATGCCAGGGG CTGGCCCTGG TGTGCCCCAG 
CTGGGAAACA TGGCTGTCAT ACATTCACAT CTGTGGAAAG GATTGCAAGA GAAGTTCTTG 
AAGGGAGAAC CCAAAGTCCT TGGGGTTGTG CAGATTCTGA CTGCCCTGAT GAGCCTTAGC 
ATGGGAATAA CAATGATGTG TATGGCATCT AATACTTATG GAAGTAACCC TATTTCCGTG 
TATATCGGGT ACACAATTTG GGGGTCAGTA ATGTTTATTA TTTCAGGATC CTTGTCAATT 
GCAGCAGGAA TTAGAACTAC AAAAGGCCTG GTCCGAGGTA GTCTAGGAAT GAATATCACC 
AGCTCTGTAC TGGCTGCATC AGGGATCTTA ATCAACACAT TTAGCTTGGC GTTTTATTCA 
TTCCATCACC CTTACTGTAA CTACTATGGC AACTCAAATA ATTGTCATGG GACTATGTCC 
ATCTTAATGG GTCTGGATGG CATGGTGCTC CTCCTAAGTG TGCTGGAATT CTGCATTGCT 
GTGTCCCTCT CTGCCTTTGG ATGTAAAGTG CTCTGTTGTA CCCCTGGTGG GGTTGTGTTA 
ATTCTGCCAT CACATTCTCA CATGGCAGAA ACAGCATCTC CCACACCACT TAATGAGGTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016873398.1
CDS	206..868
Translation	MTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV

Target ORF information:

RefSeq Version	XM_017017909.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A4A (MS4A4A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017909.2

ORF Insert Sequence:

ATGACAACCA TGCAAGGAAT GGAACAGGCC ATGCCAGGGG CTGGCCCTGG TGTGCCCCAG 
CTGGGAAACA TGGCTGTCAT ACATTCACAT CTGTGGAAAG GATTGCAAGA GAAGTTCTTG 
AAGGGAGAAC CCAAAGTCCT TGGGGTTGTG CAGATTCTGA CTGCCCTGAT GAGCCTTAGC 
ATGGGAATAA CAATGATGTG TATGGCATCT AATACTTATG GAAGTAACCC TATTTCCGTG 
TATATCGGGT ACACAATTTG GGGGTCAGTA ATGTTTATTA TTTCAGGATC CTTGTCAATT 
GCAGCAGGAA TTAGAACTAC AAAAGGCCTG GTCCGAGGTA GTCTAGGAAT GAATATCACC 
AGCTCTGTAC TGGCTGCATC AGGGATCTTA ATCAACACAT TTAGCTTGGC GTTTTATTCA 
TTCCATCACC CTTACTGTAA CTACTATGGC AACTCAAATA ATTGTCATGG GACTATGTCC 
ATCTTAATGG GTCTGGATGG CATGGTGCTC CTCCTAAGTG TGCTGGAATT CTGCATTGCT 
GTGTCCCTCT CTGCCTTTGG ATGTAAAGTG CTCTGTTGTA CCCCTGGTGG GGTTGTGTTA 
ATTCTGCCAT CACATTCTCA CATGGCAGAA ACAGCATCTC CCACACCACT TAATGAGGTT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells.
Immunology and cell biology95(7)611-619(2017 Aug)
Sanyal R,Polyak MJ,Zuccolo J,Puri M,Deng L,Roberts L,Zuba A,Storek J,Luider JM,Sundberg EM,Mansoor A,Baigorri E,Chu MP,Belch AR,Pilarski LM,Deans JP

Human gingiva transcriptome during wound healing.
Journal of clinical periodontology44(4)394-402(2017 Apr)
Wang Y,Tatakis DN

The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling.
Molecular biology of the cell26(9)1711-27(2015 May)
Cruse G,Beaven MA,Music SC,Bradding P,Gilfillan AM,Metcalfe DD

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MS4A4A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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