TUBE1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TUBE1
Entrez Gene ID	51175
Full Name	tubulin epsilon 1
Synonyms	TUBE,dJ142L7.2
General protein information	Preferred Names tubulin epsilon 1 Names tubulin epsilon chain epsilon-tubulin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q21
Summary	This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Jan 2009].
Disorder MIM:	607345

mRNA and Protein(s)

mRNA	Protein	Name
NM_016262.4	NP_057346.1	tubulin epsilon chain
NM_016262.5	NP_057346.1	tubulin epsilon chain
XM_011535875.2	XP_011534177.1	tubulin epsilon chain isoform X2
XM_017010918.1	XP_016866407.1	tubulin epsilon chain isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TUBE1	NP_057346.1
Canis lupus familiaris (dog)	TUBE1	XP_855214.2
Danio rerio (zebrafish)	tube1	NP_957279.2
Pan troglodytes (chimpanzee)	TUBE1	NP_001233321.1
Mus musculus (house mouse)	Tube1	NP_082282.1
	TUBE1	XP_001085410.2
Xenopus tropicalis (tropical clawed frog)	tube1	NP_001016136.1
Rattus norvegicus (Norway rat)	Tube1	NP_001102006.1
Gallus gallus (chicken)	TUBE1	XP_419781.2

Gene Ontology
Bibliography

Related articles in PubMed

Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells.
Wang JT, Kong D, Hoerner CR, Loncarek J, Stearns T
eLife6(2017 Sep)

Centrosome-related genes, genetic variation, and risk of breast cancer.
Olson JE, Wang X, Pankratz VS, Fredericksen ZS, Vachon CM, Vierkant RA, Cerhan JR, Couch FJ
Breast cancer research and treatment125(1)221-8(2011 Jan)

EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.
Zanic M, Stear JH, Hyman AA, Howard J
PloS one4(10)e7585(2009 Oct)

Epsilon-tubulin is required for centriole duplication and microtubule organization.
Chang P, Giddings TH Jr, Winey M, Stearns T
Nature cell biology5(1)71-6(2003 Jan)

Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function.
Chang P, Stearns T
Nature cell biology2(1)30-5(2000 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Centrosome-related genes, genetic variation, and risk of breast cancer.

EB1 recognizes the nucleotide state of tubulin in the microtubule lattice
Title: EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.

The following TUBE1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TUBE1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07243	NM_016262.5 Latest version!	Homo sapiens tubulin epsilon 1 (TUBE1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu67739	XM_011535875.2 Latest version!	Homo sapiens tubulin epsilon 1 (TUBE1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu67738	XM_017010918.1 Latest version!	Homo sapiens tubulin epsilon 1 (TUBE1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu07243	NM_016262.4	Homo sapiens tubulin epsilon 1 (TUBE1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TUBE1 ( NM_016262.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057346.1 Homo sapiens tubulin epsilon 1 (TUBE1), mRNA.

Price & Availability↑

CloneID	OHu07243
Clone ID Related Accession (Same CDS sequence)	NM_016262.4 , NM_016262.5
Accession Version	NM_016262.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	tubulin epsilon chain
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA160210.1, AK026242.1, BC025405.2 and CA411886.1. On Feb 11, 2009 this sequence version replaced NM_016262.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.66413.1, SRR1660805.124440.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCCAGT CGGTGGTCGT ACAGGTCGGC CAGTGCGGAA ACCAGATCGG CTGCTGCTTC 
TGGGACCTGG CACTAAGGGA GCACGCCGCG GTCAACCAGA AAGGAATTTA TGATGAGGCA 
ATAAGCAGCT TCTTTAGAAA TGTGGACACC AGAGTGGTTG GTGATGGTGG AAGTATTTCC 
AAGGGAAAAA TATGTTCTTT AAAAGCACGA GCAGTCTTGA TTGATATGGA AGAAGGGGTA 
GTGAATGAAA TTCTGCAGGG ACCACTGAGA GATGTATTTG ATACGAAACA GCTCATCACT 
GATATTTCTG GCTCAGGAAA TAATTGGGCC GTGGGTCACA AAGTTTTCGG CAGTCTTTAC 
CAAGACCAGA TTTTAGAGAA ATTCAGAAAG TCGGCAGAGC ACTGTGATTG CTTGCAGTGT 
TTCTTTATAA TACATTCCAT GGGAGGAGGA ACAGGATCTG GACTTGGCAC ATTTCTTTTA 
AAGGTGCTTG AAGACGAATT CCCAGAAGTA TACAGATTTG TGACTTCCAT TTATCCTTCT 
GGTGAGGATG ATGTCATAAC CTCACCTTAT AATAGCATCT TGGCAATGAA GGAACTTAAT 
GAGCATGCAG ACTGTGTATT GCCCATTGAC AATCAATCTT TATTTGACAT CATTAGCAAA 
ATCGACCTCA TGGTGAATTC TGGAAAGTTG GGTACAACTG TGAAGCCAAA GAGTCTGGTT 
ACTTCAAGTT CTGGGGCTTT AAAAAAGCAG CATAAGAAGC CCTTTGATGC AATGAATAAC 
ATTGTGGCAA ATTTGCTCCT CAACCTAACG AGCTCTGCAA GATTTGAAGG GTCCCTTAAT 
ATGGACCTTA ATGAAATCAG CATGAATTTA GTTCCTTTTC CTCAACTTCA TTATCTCGTG 
TCAAGCCTAA CACCTCTGTA TACACTGACA GATGTTAACA TTCCTCCTAG AAGATTGGAT 
CAGATGTTTT CAGATGCCTT TAGTAAAGAT CACCAGCTGC TTCGGGCAGA CCCCAAACAC 
AGTCTTTACC TCGCCTGTGC ACTCATGGTT AGAGGAAATG TACAAATTTC AGATCTTCGT 
AGAAATATTG AAAGATTAAA ACCATCTCTA CAATTTGTCT CCTGGAATCA AGAAGGCTGG 
AAGACCAGCC TGTGTTCCGT ACCTCCTGTG GGCCATTCTC ATTCGTTATT AGCTTTAGCA 
AATAACACAT GTGTGAAGCC CACCTTCATG GAACTGAAAG AGAGATTCAT GAGGCTCTAC 
AAGAAAAAGG CTCACCTTCA TCACTATCTA CAAGTTGAAG GGATGGAAGA AAGCTGTTTC 
ACAGAAGCTG TGTCATCTTT ATCAGCACTC ATACAGGAAT ATGACCAACT GGACGCCACA 
AAAAACATGC CTGTGCAGGA TTTACCCAGA CTAAGCATAG CTATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057346.1
CDS	115..1542
Translation	MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLRRNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQDLPRLSIAM

Target ORF information:

RefSeq Version	NM_016262.4
Organism	Homo sapiens(human)
Definition	Homo sapiens tubulin epsilon 1 (TUBE1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016262.4

ORF Insert Sequence:

ATGACCCAGT CGGTGGTCGT ACAGGTCGGC CAGTGCGGAA ACCAGATCGG CTGCTGCTTC 
TGGGACCTGG CACTAAGGGA GCACGCCGCG GTCAACCAGA AAGGAATTTA TGATGAGGCA 
ATAAGCAGCT TCTTTAGAAA TGTGGACACC AGAGTGGTTG GTGATGGTGG AAGTATTTCC 
AAGGGAAAAA TATGTTCTTT AAAAGCACGA GCAGTCTTGA TTGATATGGA AGAAGGGGTA 
GTGAATGAAA TTCTGCAGGG ACCACTGAGA GATGTATTTG ATACGAAACA GCTCATCACT 
GATATTTCTG GCTCAGGAAA TAATTGGGCC GTGGGTCACA AAGTTTTCGG CAGTCTTTAC 
CAAGACCAGA TTTTAGAGAA ATTCAGAAAG TCGGCAGAGC ACTGTGATTG CTTGCAGTGT 
TTCTTTATAA TACATTCCAT GGGAGGAGGA ACAGGATCTG GACTTGGCAC ATTTCTTTTA 
AAGGTGCTTG AAGACGAATT CCCAGAAGTA TACAGATTTG TGACTTCCAT TTATCCTTCT 
GGTGAGGATG ATGTCATAAC CTCACCTTAT AATAGCATCT TGGCAATGAA GGAACTTAAT 
GAGCATGCAG ACTGTGTATT GCCCATTGAC AATCAATCTT TATTTGACAT CATTAGCAAA 
ATCGACCTCA TGGTGAATTC TGGAAAGTTG GGTACAACTG TGAAGCCAAA GAGTCTGGTT 
ACTTCAAGTT CTGGGGCTTT AAAAAAGCAG CATAAGAAGC CCTTTGATGC AATGAATAAC 
ATTGTGGCAA ATTTGCTCCT CAACCTAACG AGCTCTGCAA GATTTGAAGG GTCCCTTAAT 
ATGGACCTTA ATGAAATCAG CATGAATTTA GTTCCTTTTC CTCAACTTCA TTATCTCGTG 
TCAAGCCTAA CACCTCTGTA TACACTGACA GATGTTAACA TTCCTCCTAG AAGATTGGAT 
CAGATGTTTT CAGATGCCTT TAGTAAAGAT CACCAGCTGC TTCGGGCAGA CCCCAAACAC 
AGTCTTTACC TCGCCTGTGC ACTCATGGTT AGAGGAAATG TACAAATTTC AGATCTTCGT 
AGAAATATTG AAAGATTAAA ACCATCTCTA CAATTTGTCT CCTGGAATCA AGAAGGCTGG 
AAGACCAGCC TGTGTTCCGT ACCTCCTGTG GGCCATTCTC ATTCGTTATT AGCTTTAGCA 
AATAACACAT GTGTGAAGCC CACCTTCATG GAACTGAAAG AGAGATTCAT GAGGCTCTAC 
AAGAAAAAGG CTCACCTTCA TCACTATCTA CAAGTTGAAG GGATGGAAGA AAGCTGTTTC 
ACAGAAGCTG TGTCATCTTT ATCAGCACTC ATACAGGAAT ATGACCAACT GGACGCCACA 
AAAAACATGC CTGTGCAGGA TTTACCCAGA CTAAGCATAG CTATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TUBE1 ( NM_016262.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_057346.1 Homo sapiens tubulin epsilon 1 (TUBE1), mRNA.

Price & Availability↑

CloneID	OHu07243
Clone ID Related Accession (Same CDS sequence)	NM_016262.4 , NM_016262.5
Accession Version	NM_016262.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	tubulin epsilon chain
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK026242.1, BC025405.2 and CA411886.1. On Nov 23, 2018 this sequence version replaced NM_016262.4. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.52898.1, SRR1660805.124440.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000368662.10/ ENSP00000357651.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACCCAGT CGGTGGTCGT ACAGGTCGGC CAGTGCGGAA ACCAGATCGG CTGCTGCTTC 
TGGGACCTGG CACTAAGGGA GCACGCCGCG GTCAACCAGA AAGGAATTTA TGATGAGGCA 
ATAAGCAGCT TCTTTAGAAA TGTGGACACC AGAGTGGTTG GTGATGGTGG AAGTATTTCC 
AAGGGAAAAA TATGTTCTTT AAAAGCACGA GCAGTCTTGA TTGATATGGA AGAAGGGGTA 
GTGAATGAAA TTCTGCAGGG ACCACTGAGA GATGTATTTG ATACGAAACA GCTCATCACT 
GATATTTCTG GCTCAGGAAA TAATTGGGCC GTGGGTCACA AAGTTTTCGG CAGTCTTTAC 
CAAGACCAGA TTTTAGAGAA ATTCAGAAAG TCGGCAGAGC ACTGTGATTG CTTGCAGTGT 
TTCTTTATAA TACATTCCAT GGGAGGAGGA ACAGGATCTG GACTTGGCAC ATTTCTTTTA 
AAGGTGCTTG AAGACGAATT CCCAGAAGTA TACAGATTTG TGACTTCCAT TTATCCTTCT 
GGTGAGGATG ATGTCATAAC CTCACCTTAT AATAGCATCT TGGCAATGAA GGAACTTAAT 
GAGCATGCAG ACTGTGTATT GCCCATTGAC AATCAATCTT TATTTGACAT CATTAGCAAA 
ATCGACCTCA TGGTGAATTC TGGAAAGTTG GGTACAACTG TGAAGCCAAA GAGTCTGGTT 
ACTTCAAGTT CTGGGGCTTT AAAAAAGCAG CATAAGAAGC CCTTTGATGC AATGAATAAC 
ATTGTGGCAA ATTTGCTCCT CAACCTAACG AGCTCTGCAA GATTTGAAGG GTCCCTTAAT 
ATGGACCTTA ATGAAATCAG CATGAATTTA GTTCCTTTTC CTCAACTTCA TTATCTCGTG 
TCAAGCCTAA CACCTCTGTA TACACTGACA GATGTTAACA TTCCTCCTAG AAGATTGGAT 
CAGATGTTTT CAGATGCCTT TAGTAAAGAT CACCAGCTGC TTCGGGCAGA CCCCAAACAC 
AGTCTTTACC TCGCCTGTGC ACTCATGGTT AGAGGAAATG TACAAATTTC AGATCTTCGT 
AGAAATATTG AAAGATTAAA ACCATCTCTA CAATTTGTCT CCTGGAATCA AGAAGGCTGG 
AAGACCAGCC TGTGTTCCGT ACCTCCTGTG GGCCATTCTC ATTCGTTATT AGCTTTAGCA 
AATAACACAT GTGTGAAGCC CACCTTCATG GAACTGAAAG AGAGATTCAT GAGGCTCTAC 
AAGAAAAAGG CTCACCTTCA TCACTATCTA CAAGTTGAAG GGATGGAAGA AAGCTGTTTC 
ACAGAAGCTG TGTCATCTTT ATCAGCACTC ATACAGGAAT ATGACCAACT GGACGCCACA 
AAAAACATGC CTGTGCAGGA TTTACCCAGA CTAAGCATAG CTATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057346.1
CDS	49..1476
Translation	MTQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISSFFRNVDTRVVGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLRRNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQDLPRLSIAM

Target ORF information:

RefSeq Version	NM_016262.5
Organism	Homo sapiens(human)
Definition	Homo sapiens tubulin epsilon 1 (TUBE1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016262.5

ORF Insert Sequence:

ATGACCCAGT CGGTGGTCGT ACAGGTCGGC CAGTGCGGAA ACCAGATCGG CTGCTGCTTC 
TGGGACCTGG CACTAAGGGA GCACGCCGCG GTCAACCAGA AAGGAATTTA TGATGAGGCA 
ATAAGCAGCT TCTTTAGAAA TGTGGACACC AGAGTGGTTG GTGATGGTGG AAGTATTTCC 
AAGGGAAAAA TATGTTCTTT AAAAGCACGA GCAGTCTTGA TTGATATGGA AGAAGGGGTA 
GTGAATGAAA TTCTGCAGGG ACCACTGAGA GATGTATTTG ATACGAAACA GCTCATCACT 
GATATTTCTG GCTCAGGAAA TAATTGGGCC GTGGGTCACA AAGTTTTCGG CAGTCTTTAC 
CAAGACCAGA TTTTAGAGAA ATTCAGAAAG TCGGCAGAGC ACTGTGATTG CTTGCAGTGT 
TTCTTTATAA TACATTCCAT GGGAGGAGGA ACAGGATCTG GACTTGGCAC ATTTCTTTTA 
AAGGTGCTTG AAGACGAATT CCCAGAAGTA TACAGATTTG TGACTTCCAT TTATCCTTCT 
GGTGAGGATG ATGTCATAAC CTCACCTTAT AATAGCATCT TGGCAATGAA GGAACTTAAT 
GAGCATGCAG ACTGTGTATT GCCCATTGAC AATCAATCTT TATTTGACAT CATTAGCAAA 
ATCGACCTCA TGGTGAATTC TGGAAAGTTG GGTACAACTG TGAAGCCAAA GAGTCTGGTT 
ACTTCAAGTT CTGGGGCTTT AAAAAAGCAG CATAAGAAGC CCTTTGATGC AATGAATAAC 
ATTGTGGCAA ATTTGCTCCT CAACCTAACG AGCTCTGCAA GATTTGAAGG GTCCCTTAAT 
ATGGACCTTA ATGAAATCAG CATGAATTTA GTTCCTTTTC CTCAACTTCA TTATCTCGTG 
TCAAGCCTAA CACCTCTGTA TACACTGACA GATGTTAACA TTCCTCCTAG AAGATTGGAT 
CAGATGTTTT CAGATGCCTT TAGTAAAGAT CACCAGCTGC TTCGGGCAGA CCCCAAACAC 
AGTCTTTACC TCGCCTGTGC ACTCATGGTT AGAGGAAATG TACAAATTTC AGATCTTCGT 
AGAAATATTG AAAGATTAAA ACCATCTCTA CAATTTGTCT CCTGGAATCA AGAAGGCTGG 
AAGACCAGCC TGTGTTCCGT ACCTCCTGTG GGCCATTCTC ATTCGTTATT AGCTTTAGCA 
AATAACACAT GTGTGAAGCC CACCTTCATG GAACTGAAAG AGAGATTCAT GAGGCTCTAC 
AAGAAAAAGG CTCACCTTCA TCACTATCTA CAAGTTGAAG GGATGGAAGA AAGCTGTTTC 
ACAGAAGCTG TGTCATCTTT ATCAGCACTC ATACAGGAAT ATGACCAACT GGACGCCACA 
AAAAACATGC CTGTGCAGGA TTTACCCAGA CTAAGCATAG CTATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TUBE1 ( XM_011535875.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534177.1 Homo sapiens tubulin epsilon 1 (TUBE1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu67739
Clone ID Related Accession (Same CDS sequence)	XM_011535875.2
Accession Version	XM_011535875.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tubulin epsilon chain isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535875.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAAG GGGTAGTGAA TGAAATTCTG CAGGGACCAC TGAGAGATGT ATTTGATACG 
AAACAGCTCA TCACTGATAT TTCTGGCTCA GGAAATAATT GGGCCGTGGG TCACAAAGTT 
TTCGGCAGTC TTTACCAAGA CCAGATTTTA GAGAAATTCA GAAAGTCGGC AGAGCACTGT 
GATTGCTTGC AGTGTTTCTT TATAATACAT TCCATGGGAG GAGGAACAGG ATCTGGACTT 
GGCACATTTC TTTTAAAGGT GCTTGAAGAC GAATTCCCAG AAGTATACAG ATTTGTGACT 
TCCATTTATC CTTCTGGTGA GGATGATGTC ATAACCTCAC CTTATAATAG CATCTTGGCA 
ATGAAGGAAC TTAATGAGCA TGCAGACTGT GTATTGCCCA TTGACAATCA ATCTTTATTT 
GACATCATTA GCAAAATCGA CCTCATGGTG AATTCTGGAA AGTTGGGTAC AACTGTGAAG 
CCAAAGAGTC TGGTTACTTC AAGTTCTGGG GCTTTAAAAA AGCAGCATAA GAAGCCCTTT 
GATGCAATGA ATAACATTGT GGCAAATTTG CTCCTCAACC TAACGAGCTC TGCAAGATTT 
GAAGGGTCCC TTAATATGGA CCTTAATGAA ATCAGCATGA ATTTAGTTCC TTTTCCTCAA 
CTTCATTATC TCGTGTCAAG CCTAACACCT CTGTATACAC TGACAGATGT TAACATTCCT 
CCTAGAAGAT TGGATCAGAT GTTTTCAGAT GCCTTTAGTA AAGATCACCA GCTGCTTCGG 
GCAGACCCCA AACACAGTCT TTACCTCGCC TGTGCACTCA TGGTTAGAGG AAATGTACAA 
ATTTCAGATC TTCGTAGAAA TATTGAAAGA TTAAAACCAT CTCTACAATT TGTCTCCTGG 
AATCAAGAAG GCTGGAAGAC CAGCCTGTGT TCCGTACCTC CTGTGGGCCA TTCTCATTCG 
TTATTAGCTT TAGCAAATAA CACATGTGTG AAGCCCACCT TCATGGAACT GAAAGAGAGA 
TTCATGAGGC TCTACAAGAA AAAGGCTCAC CTTCATCACT ATCTACAAGT TGAAGGGATG 
GAAGAAAGCT GTTTCACAGA AGCTGTGTCA TCTTTATCAG CACTCATACA GGAATATGAC 
CAACTGGACG CCACAAAAAA CATGCCTGTG CAGGATTTAC CCAGACTAAG CATAGCTATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534177.1
CDS	263..1465
Translation	MEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLRRNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQDLPRLSIAM

Target ORF information:

RefSeq Version	XM_011535875.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tubulin epsilon 1 (TUBE1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535875.2

ORF Insert Sequence:

ATGGAAGAAG GGGTAGTGAA TGAAATTCTG CAGGGACCAC TGAGAGATGT ATTTGATACG 
AAACAGCTCA TCACTGATAT TTCTGGCTCA GGAAATAATT GGGCCGTGGG TCACAAAGTT 
TTCGGCAGTC TTTACCAAGA CCAGATTTTA GAGAAATTCA GAAAGTCGGC AGAGCACTGT 
GATTGCTTGC AGTGTTTCTT TATAATACAT TCCATGGGAG GAGGAACAGG ATCTGGACTT 
GGCACATTTC TTTTAAAGGT GCTTGAAGAC GAATTCCCAG AAGTATACAG ATTTGTGACT 
TCCATTTATC CTTCTGGTGA GGATGATGTC ATAACCTCAC CTTATAATAG CATCTTGGCA 
ATGAAGGAAC TTAATGAGCA TGCAGACTGT GTATTGCCCA TTGACAATCA ATCTTTATTT 
GACATCATTA GCAAAATCGA CCTCATGGTG AATTCTGGAA AGTTGGGTAC AACTGTGAAG 
CCAAAGAGTC TGGTTACTTC AAGTTCTGGG GCTTTAAAAA AGCAGCATAA GAAGCCCTTT 
GATGCAATGA ATAACATTGT GGCAAATTTG CTCCTCAACC TAACGAGCTC TGCAAGATTT 
GAAGGGTCCC TTAATATGGA CCTTAATGAA ATCAGCATGA ATTTAGTTCC TTTTCCTCAA 
CTTCATTATC TCGTGTCAAG CCTAACACCT CTGTATACAC TGACAGATGT TAACATTCCT 
CCTAGAAGAT TGGATCAGAT GTTTTCAGAT GCCTTTAGTA AAGATCACCA GCTGCTTCGG 
GCAGACCCCA AACACAGTCT TTACCTCGCC TGTGCACTCA TGGTTAGAGG AAATGTACAA 
ATTTCAGATC TTCGTAGAAA TATTGAAAGA TTAAAACCAT CTCTACAATT TGTCTCCTGG 
AATCAAGAAG GCTGGAAGAC CAGCCTGTGT TCCGTACCTC CTGTGGGCCA TTCTCATTCG 
TTATTAGCTT TAGCAAATAA CACATGTGTG AAGCCCACCT TCATGGAACT GAAAGAGAGA 
TTCATGAGGC TCTACAAGAA AAAGGCTCAC CTTCATCACT ATCTACAAGT TGAAGGGATG 
GAAGAAAGCT GTTTCACAGA AGCTGTGTCA TCTTTATCAG CACTCATACA GGAATATGAC 
CAACTGGACG CCACAAAAAA CATGCCTGTG CAGGATTTAC CCAGACTAAG CATAGCTATG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TUBE1 ( XM_017010918.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016866407.1 Homo sapiens tubulin epsilon 1 (TUBE1), transcript variant X1, mRNA.

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CloneID	OHu67738
Clone ID Related Accession (Same CDS sequence)	XM_017010918.1
Accession Version	XM_017010918.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tubulin epsilon chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCAG ACCAAAGGAA AGTGGTTGGT GATGGTGGAA GTATTTCCAA GGGAAAAATA 
TGTTCTTTAA AAGCACGAGC AGTCTTGATT GATATGGAAG AAGGGGTAGT GAATGAAATT 
CTGCAGGGAC CACTGAGAGA TGTATTTGAT ACGAAACAGC TCATCACTGA TATTTCTGGC 
TCAGGAAATA ATTGGGCCGT GGGTCACAAA GTTTTCGGCA GTCTTTACCA AGACCAGATT 
TTAGAGAAAT TCAGAAAGTC GGCAGAGCAC TGTGATTGCT TGCAGTGTTT CTTTATAATA 
CATTCCATGG GAGGAGGAAC AGGATCTGGA CTTGGCACAT TTCTTTTAAA GGTGCTTGAA 
GACGAATTCC CAGAAGTATA CAGATTTGTG ACTTCCATTT ATCCTTCTGG TGAGGATGAT 
GTCATAACCT CACCTTATAA TAGCATCTTG GCAATGAAGG AACTTAATGA GCATGCAGAC 
TGTGTATTGC CCATTGACAA TCAATCTTTA TTTGACATCA TTAGCAAAAT CGACCTCATG 
GTGAATTCTG GAAAGTTGGG TACAACTGTG AAGCCAAAGA GTCTGGTTAC TTCAAGTTCT 
GGGGCTTTAA AAAAGCAGCA TAAGAAGCCC TTTGATGCAA TGAATAACAT TGTGGCAAAT 
TTGCTCCTCA ACCTAACGAG CTCTGCAAGA TTTGAAGGGT CCCTTAATAT GGACCTTAAT 
GAAATCAGCA TGAATTTAGT TCCTTTTCCT CAACTTCATT ATCTCGTGTC AAGCCTAACA 
CCTCTGTATA CACTGACAGA TGTTAACATT CCTCCTAGAA GATTGGATCA GATGTTTTCA 
GATGCCTTTA GTAAAGATCA CCAGCTGCTT CGGGCAGACC CCAAACACAG TCTTTACCTC 
GCCTGTGCAC TCATGGTTAG AGGAAATGTA CAAATTTCAG ATCTTCGTAG AAATATTGAA 
AGATTAAAAC CATCTCTACA ATTTGTCTCC TGGAATCAAG AAGGCTGGAA GACCAGCCTG 
TGTTCCGTAC CTCCTGTGGG CCATTCTCAT TCGTTATTAG CTTTAGCAAA TAACACATGT 
GTGAAGCCCA CCTTCATGGA ACTGAAAGAG AGATTCATGA GGCTCTACAA GAAAAAGGCT 
CACCTTCATC ACTATCTACA AGTTGAAGGG ATGGAAGAAA GCTGTTTCAC AGAAGCTGTG 
TCATCTTTAT CAGCACTCAT ACAGGAATAT GACCAACTGG ACGCCACAAA AAACATGCCT 
GTGCAGGATT TACCCAGACT AAGCATAGCT ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016866407.1
CDS	261..1556
Translation	MESDQRKVVGDGGSISKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDISGSGNNWAVGHKVFGSLYQDQILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGEDDVITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALKKQHKKPFDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTLTDVNIPPRRLDQMFSDAFSKDHQLLRADPKHSLYLACALMVRGNVQISDLRRNIERLKPSLQFVSWNQEGWKTSLCSVPPVGHSHSLLALANNTCVKPTFMELKERFMRLYKKKAHLHHYLQVEGMEESCFTEAVSSLSALIQEYDQLDATKNMPVQDLPRLSIAM

Target ORF information:

RefSeq Version	XM_017010918.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tubulin epsilon 1 (TUBE1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010918.1

ORF Insert Sequence:

ATGGAATCAG ACCAAAGGAA AGTGGTTGGT GATGGTGGAA GTATTTCCAA GGGAAAAATA 
TGTTCTTTAA AAGCACGAGC AGTCTTGATT GATATGGAAG AAGGGGTAGT GAATGAAATT 
CTGCAGGGAC CACTGAGAGA TGTATTTGAT ACGAAACAGC TCATCACTGA TATTTCTGGC 
TCAGGAAATA ATTGGGCCGT GGGTCACAAA GTTTTCGGCA GTCTTTACCA AGACCAGATT 
TTAGAGAAAT TCAGAAAGTC GGCAGAGCAC TGTGATTGCT TGCAGTGTTT CTTTATAATA 
CATTCCATGG GAGGAGGAAC AGGATCTGGA CTTGGCACAT TTCTTTTAAA GGTGCTTGAA 
GACGAATTCC CAGAAGTATA CAGATTTGTG ACTTCCATTT ATCCTTCTGG TGAGGATGAT 
GTCATAACCT CACCTTATAA TAGCATCTTG GCAATGAAGG AACTTAATGA GCATGCAGAC 
TGTGTATTGC CCATTGACAA TCAATCTTTA TTTGACATCA TTAGCAAAAT CGACCTCATG 
GTGAATTCTG GAAAGTTGGG TACAACTGTG AAGCCAAAGA GTCTGGTTAC TTCAAGTTCT 
GGGGCTTTAA AAAAGCAGCA TAAGAAGCCC TTTGATGCAA TGAATAACAT TGTGGCAAAT 
TTGCTCCTCA ACCTAACGAG CTCTGCAAGA TTTGAAGGGT CCCTTAATAT GGACCTTAAT 
GAAATCAGCA TGAATTTAGT TCCTTTTCCT CAACTTCATT ATCTCGTGTC AAGCCTAACA 
CCTCTGTATA CACTGACAGA TGTTAACATT CCTCCTAGAA GATTGGATCA GATGTTTTCA 
GATGCCTTTA GTAAAGATCA CCAGCTGCTT CGGGCAGACC CCAAACACAG TCTTTACCTC 
GCCTGTGCAC TCATGGTTAG AGGAAATGTA CAAATTTCAG ATCTTCGTAG AAATATTGAA 
AGATTAAAAC CATCTCTACA ATTTGTCTCC TGGAATCAAG AAGGCTGGAA GACCAGCCTG 
TGTTCCGTAC CTCCTGTGGG CCATTCTCAT TCGTTATTAG CTTTAGCAAA TAACACATGT 
GTGAAGCCCA CCTTCATGGA ACTGAAAGAG AGATTCATGA GGCTCTACAA GAAAAAGGCT 
CACCTTCATC ACTATCTACA AGTTGAAGGG ATGGAAGAAA GCTGTTTCAC AGAAGCTGTG 
TCATCTTTAT CAGCACTCAT ACAGGAATAT GACCAACTGG ACGCCACAAA AAACATGCCT 
GTGCAGGATT TACCCAGACT AAGCATAGCT ATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells.
eLife6(2017 Sep)
Wang JT,Kong D,Hoerner CR,Loncarek J,Stearns T

Centrosome-related genes, genetic variation, and risk of breast cancer.
Breast cancer research and treatment125(1)221-8(2011 Jan)
Olson JE,Wang X,Pankratz VS,Fredericksen ZS,Vachon CM,Vierkant RA,Cerhan JR,Couch FJ

EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.
PloS one4(10)e7585(2009 Oct)
Zanic M,Stear JH,Hyman AA,Howard J

Epsilon-tubulin is required for centriole duplication and microtubule organization.
Nature cell biology5(1)71-6(2003 Jan)
Chang P,Giddings TH Jr,Winey M,Stearns T

Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function.
Nature cell biology2(1)30-5(2000 Jan)
Chang P,Stearns T