C1QL3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	C1QL3
Entrez Gene ID	389941
Full Name	complement C1q like 3
Synonyms	C1QTNF13,C1ql,CTRP13,K100
General protein information	Preferred Names complement C1q like 3 Names complement C1q-like protein 3 C1q and tumor necrosis factor-related protein 13 C1q/TNF-related protein 13 complement component 1, q subcomponent-like 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10p13
Disorder MIM:	615227

mRNA and Protein(s)

mRNA	Protein	Name
NM_001010908.1	NP_001010908.1	complement C1q-like protein 3 precursor
NM_001010908.2	NP_001010908.1	complement C1q-like protein 3 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	C1QL3	NP_001010908.1
Xenopus tropicalis (tropical clawed frog)	c1ql3	XP_002939047.1
	C1QL3	XP_002805612.1
Canis lupus familiaris (dog)	C1QL3	XP_848586.2
Mus musculus (house mouse)	C1ql3	NP_694795.1
Rattus norvegicus (Norway rat)	C1ql3	NP_001102873.1
Danio rerio (zebrafish)	c1ql3a	XP_001923507.3
Pan troglodytes (chimpanzee)	C1QL3	XP_001149904.1
Bos taurus (cattle)	C1QL3	NP_001193093.1

Gene Ontology
Bibliography

Related articles in PubMed

The Circulating Levels of Complement-C1q/TNF-Related Protein 13 (CTRP13) in Patients with Type 2 Diabetes and its Association with Insulin Resistance.
Afrookhteh A, Emamgholipour S, Alipoor B, Moradi N, Meshkani R, Nasli-Esfahani E, Rahimipour A, Shanaki M
Clinical laboratory63(2)327-333(2017 Feb)

Association of C1q/TNF-Related Protein-3 (CTRP3) and CTRP13 Serum Levels with Coronary Artery Disease in Subjects with and without Type 2 Diabetes Mellitus.
Fadaei R, Moradi N, Baratchian M, Aghajani H, Malek M, Fazaeli AA, Fallah S
PloS one11(12)e0168773(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CTRP13 is a novel adipokine that is down-regulated in the serum of type 2 diabetics.
Title: The Circulating Levels of Complement-C1q/TNF-Related Protein 13 (CTRP13) in Patients with Type 2 Diabetes and its Association with Insulin Resistance.

decreased levels of CTRP3 and especially CTRP13 were associated with increased risk of T2DM and CAD
Title: Association of C1q/TNF-Related Protein-3 (CTRP3) and CTRP13 Serum Levels with Coronary Artery Disease in Subjects with and without Type 2 Diabetes Mellitus.

CTRP13 reduces glucose output in hepatocytes by inhibiting the mRNA expression of gluconeogenic enzymes, glucose-6-phosphatase and the cytosolic form of phosphoenolpyruvate carboxykinase.
Title: Metabolic regulation by C1q/TNF-related protein-13 (CTRP13): activation OF AMP-activated protein kinase and suppression of fatty acid-induced JNK signaling.

The following C1QL3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C1QL3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24409	NM_001010908.2 Latest version!	Homo sapiens complement C1q like 3 (C1QL3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
View Old Accession Versions >>
OHu24409	NM_001010908.1	Homo sapiens complement C1q like 3 (C1QL3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C1QL3 ( NM_001010908.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001010908.1 Homo sapiens complement C1q like 3 (C1QL3), mRNA.

Price & Availability↑

CloneID	OHu24409
Clone ID Related Accession (Same CDS sequence)	NM_001010908.1 , NM_001010908.2
Accession Version	NM_001010908.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	complement C1q-like protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL353576.18 and AL360230.20. On Mar 22, 2005 this sequence version replaced XM_372305.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.186834.1, SRR1803611.209128.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGTGCTGC TGCTGGTGAT CCTCATCCCG GTGCTGGTGA GCTCGGCCGG CACGTCGGCG 
CACTACGAGA TGCTGGGCAC CTGCCGCATG GTCTGCGACC CCTACGGGGG CACCAAGGCG 
CCCAGCACCG CTGCCACGCC CGACCGCGGC CTCATGCAGT CCCTGCCCAC CTTCATCCAG 
GGCCCCAAAG GCGAGGCCGG CAGGCCCGGG AAGGCGGGTC CGCGCGGGCC CCCCGGAGAG 
CCCGGGCCAC CCGGCCCCAT GGGGCCCCCG GGCGAGAAGG GCGAGCCGGG CCGCCAAGGC 
CTGCCGGGCC CGCCCGGGGC GCCCGGCCTG AACGCGGCCG GGGCCATCAG CGCCGCCACC 
TACAGCACGG TGCCCAAGAT CGCCTTCTAC GCCGGCCTCA AGCGGCAGCA TGAAGGCTAC 
GAGGTGCTCA AGTTCGACGA CGTGGTCACC AACCTCGGAA ACCACTACGA CCCCACCACC 
GGCAAGTTCA CCTGCTCCAT CCCGGGCATC TACTTCTTCA CCTACCACGT CCTGATGCGC 
GGAGGGGACG GCACCAGCAT GTGGGCTGAT CTCTGCAAAA ACAACCAGGT GCGTGCTAGT 
GCAATTGCCC AAGATGCTGA TCAGAATTAC GACTATGCCA GTAACAGTGT GGTTCTTCAT 
TTGGAGCCGG GAGATGAAGT CTATATCAAA TTAGATGGCG GGAAAGCCCA TGGAGGAAAC 
AACAACAAAT ACAGCACGTT TTCTGGATTT ATTATTTATG CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001010908.1
CDS	941..1708
Translation	MVLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPMGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD

Target ORF information:

RefSeq Version	NM_001010908.1
Organism	Homo sapiens(human)
Definition	Homo sapiens complement C1q like 3 (C1QL3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001010908.1

ORF Insert Sequence:

ATGGTGCTGC TGCTGGTGAT CCTCATCCCG GTGCTGGTGA GCTCGGCCGG CACGTCGGCG 
CACTACGAGA TGCTGGGCAC CTGCCGCATG GTCTGCGACC CCTACGGGGG CACCAAGGCG 
CCCAGCACCG CTGCCACGCC CGACCGCGGC CTCATGCAGT CCCTGCCCAC CTTCATCCAG 
GGCCCCAAAG GCGAGGCCGG CAGGCCCGGG AAGGCGGGTC CGCGCGGGCC CCCCGGAGAG 
CCCGGGCCAC CCGGCCCCAT GGGGCCCCCG GGCGAGAAGG GCGAGCCGGG CCGCCAAGGC 
CTGCCGGGCC CGCCCGGGGC GCCCGGCCTG AACGCGGCCG GGGCCATCAG CGCCGCCACC 
TACAGCACGG TGCCCAAGAT CGCCTTCTAC GCCGGCCTCA AGCGGCAGCA TGAAGGCTAC 
GAGGTGCTCA AGTTCGACGA CGTGGTCACC AACCTCGGAA ACCACTACGA CCCCACCACC 
GGCAAGTTCA CCTGCTCCAT CCCGGGCATC TACTTCTTCA CCTACCACGT CCTGATGCGC 
GGAGGGGACG GCACCAGCAT GTGGGCTGAT CTCTGCAAAA ACAACCAGGT GCGTGCTAGT 
GCAATTGCCC AAGATGCTGA TCAGAATTAC GACTATGCCA GTAACAGTGT GGTTCTTCAT 
TTGGAGCCGG GAGATGAAGT CTATATCAAA TTAGATGGCG GGAAAGCCCA TGGAGGAAAC 
AACAACAAAT ACAGCACGTT TTCTGGATTT ATTATTTATG CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C1QL3 ( NM_001010908.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001010908.1 Homo sapiens complement C1q like 3 (C1QL3), mRNA.

Price & Availability↑

CloneID	OHu24409
Clone ID Related Accession (Same CDS sequence)	NM_001010908.1 , NM_001010908.2
Accession Version	NM_001010908.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	complement C1q-like protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL353576.18 and AL360230.20. On Nov 22, 2018 this sequence version replaced NM_001010908.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.186834.1, SRR1803611.209128.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000298943.4/ ENSP00000298943.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGCTGC TGCTGGTGAT CCTCATCCCG GTGCTGGTGA GCTCGGCCGG CACGTCGGCG 
CACTACGAGA TGCTGGGCAC CTGCCGCATG GTCTGCGACC CCTACGGGGG CACCAAGGCG 
CCCAGCACCG CTGCCACGCC CGACCGCGGC CTCATGCAGT CCCTGCCCAC CTTCATCCAG 
GGCCCCAAAG GCGAGGCCGG CAGGCCCGGG AAGGCGGGTC CGCGCGGGCC CCCCGGAGAG 
CCCGGGCCAC CCGGCCCCAT GGGGCCCCCG GGCGAGAAGG GCGAGCCGGG CCGCCAAGGC 
CTGCCGGGCC CGCCCGGGGC GCCCGGCCTG AACGCGGCCG GGGCCATCAG CGCCGCCACC 
TACAGCACGG TGCCCAAGAT CGCCTTCTAC GCCGGCCTCA AGCGGCAGCA TGAAGGCTAC 
GAGGTGCTCA AGTTCGACGA CGTGGTCACC AACCTCGGAA ACCACTACGA CCCCACCACC 
GGCAAGTTCA CCTGCTCCAT CCCGGGCATC TACTTCTTCA CCTACCACGT CCTGATGCGC 
GGAGGGGACG GCACCAGCAT GTGGGCTGAT CTCTGCAAAA ACAACCAGGT GCGTGCTAGT 
GCAATTGCCC AAGATGCTGA TCAGAATTAC GACTATGCCA GTAACAGTGT GGTTCTTCAT 
TTGGAGCCGG GAGATGAAGT CTATATCAAA TTAGATGGCG GGAAAGCCCA TGGAGGAAAC 
AACAACAAAT ACAGCACGTT TTCTGGATTT ATTATTTATG CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001010908.1
CDS	815..1582
Translation	MVLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPMGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD

Target ORF information:

RefSeq Version	NM_001010908.2
Organism	Homo sapiens(human)
Definition	Homo sapiens complement C1q like 3 (C1QL3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001010908.2

ORF Insert Sequence:

ATGGTGCTGC TGCTGGTGAT CCTCATCCCG GTGCTGGTGA GCTCGGCCGG CACGTCGGCG 
CACTACGAGA TGCTGGGCAC CTGCCGCATG GTCTGCGACC CCTACGGGGG CACCAAGGCG 
CCCAGCACCG CTGCCACGCC CGACCGCGGC CTCATGCAGT CCCTGCCCAC CTTCATCCAG 
GGCCCCAAAG GCGAGGCCGG CAGGCCCGGG AAGGCGGGTC CGCGCGGGCC CCCCGGAGAG 
CCCGGGCCAC CCGGCCCCAT GGGGCCCCCG GGCGAGAAGG GCGAGCCGGG CCGCCAAGGC 
CTGCCGGGCC CGCCCGGGGC GCCCGGCCTG AACGCGGCCG GGGCCATCAG CGCCGCCACC 
TACAGCACGG TGCCCAAGAT CGCCTTCTAC GCCGGCCTCA AGCGGCAGCA TGAAGGCTAC 
GAGGTGCTCA AGTTCGACGA CGTGGTCACC AACCTCGGAA ACCACTACGA CCCCACCACC 
GGCAAGTTCA CCTGCTCCAT CCCGGGCATC TACTTCTTCA CCTACCACGT CCTGATGCGC 
GGAGGGGACG GCACCAGCAT GTGGGCTGAT CTCTGCAAAA ACAACCAGGT GCGTGCTAGT 
GCAATTGCCC AAGATGCTGA TCAGAATTAC GACTATGCCA GTAACAGTGT GGTTCTTCAT 
TTGGAGCCGG GAGATGAAGT CTATATCAAA TTAGATGGCG GGAAAGCCCA TGGAGGAAAC 
AACAACAAAT ACAGCACGTT TTCTGGATTT ATTATTTATG CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Circulating Levels of Complement-C1q/TNF-Related Protein 13 (CTRP13) in Patients with Type 2 Diabetes and its Association with Insulin Resistance.
Clinical laboratory63(2)327-333(2017 Feb)
Afrookhteh A,Emamgholipour S,Alipoor B,Moradi N,Meshkani R,Nasli-Esfahani E,Rahimipour A,Shanaki M

Association of C1q/TNF-Related Protein-3 (CTRP3) and CTRP13 Serum Levels with Coronary Artery Disease in Subjects with and without Type 2 Diabetes Mellitus.
PloS one11(12)e0168773(2016)
Fadaei R,Moradi N,Baratchian M,Aghajani H,Malek M,Fazaeli AA,Fallah S