IFNA17 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IFNA17
Entrez Gene ID	3451
Full Name	interferon alpha 17
Synonyms	IFN-alphaI,IFNA,INFA,LEIF2C1
General protein information	Preferred Names interferon alpha 17 Names interferon alpha-17 IFN-alpha-17 interferon alpha-88 interferon alpha-I' interferon alpha-T interferon alpha-WA leIF I
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p21.3
Disorder MIM:	147583

mRNA and Protein(s)

mRNA	Protein	Name
NM_021268.2	NP_067091.1	interferon alpha-17 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC473191	XP_001152078.1
	LOC710848	XP_001107817.1
	LOC710931	XP_001107884.1
	LOC711170	XP_001107999.1
Homo sapiens (human)	IFNA17	NP_067091.1
	LOC711088	XP_001107940.1
	LOC710751	XP_001107754.1

Gene Ontology
Bibliography

Related articles in PubMed

Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.
Yang XR, Liang X, Pfeiffer RM, Wheeler W, Maeder D, Burdette L, Yeager M, Chanock S, Tucker MA, Goldstein AM
Familial cancer9(4)625-33(2010 Dec)

Dengue hemorrhagic fever is associated with polymorphisms in JAK1.
Silva LK, Blanton RE, Parrado AR, Melo PS, Morato VG, Reis EA, Dias JP, Castro JM, Vasconcelos PF, Goddard KA, Barreto ML, Reis MG, Teixeira MG
European journal of human genetics : EJHG18(11)1221-7(2010 Nov)

Cystic fibrosis conductance regulator, tumor necrosis factor, interferon alpha-10, interferon alpha-17, and interferon gamma genotyping as potential risk markers in pulmonary sarcoidosis pathogenesis in Greek patients.
Makrythanasis P, Tzetis M, Rapti A, Papatheodorou A, Tsipi M, Kitsiou S, Tsiamouri A, Poulou M, Roussos C, Kanavakis E
Genetic testing and molecular biomarkers14(4)577-84(2010 Aug)

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.
Mosbruger TL, Duggal P, Goedert JJ, Kirk GD, Hoots WK, Tobler LH, Busch M, Peters MG, Rosen HR, Thomas DL, Thio CL
The Journal of infectious diseases201(9)1371-80(2010 May)

Efficient expression in Escherichia coli of two species of human interferon-alpha and their hybrid molecules.
Mizoguchi J, Pitha PM, Raj NB
DNA (Mary Ann Liebert, Inc.)4(3)221-32(1985 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results show that IFNA1 rs1332190 and IFNA17 rs9298814 SNPs may play an important role in Crimean-Congo hemorrhagic fever susceptibility
Title: Relationship between IFNA1, IFNA5, IFNA10, and IFNA17 gene polymorphisms and Crimean-Congo hemorrhagic fever prognosis in a Turkish population range.

Observational study of gene-disease association. (HuGE Navigator)
Title: Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.

Observational study of gene-disease association. (HuGE Navigator)
Title: Dengue hemorrhagic fever is associated with polymorphisms in JAK1.

Observational study of gene-disease association. (HuGE Navigator)
Title: Cystic fibrosis conductance regulator, tumor necrosis factor, interferon alpha-10, interferon alpha-17, and interferon gamma genotyping as potential risk markers in pulmonary sarcoidosis pathogenesis in Greek patients.

Observational study of gene-disease association. (HuGE Navigator)
Title: Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.

The following IFNA17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IFNA17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu12610	NM_021268.2 Latest version!	Homo sapiens interferon alpha 17 (IFNA17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IFNA17 ( NM_021268.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_067091.1 Homo sapiens interferon alpha 17 (IFNA17), mRNA.

Price & Availability↑

CloneID	OHu12610
Clone ID Related Accession (Same CDS sequence)	NM_021268.2
Accession Version	NM_021268.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	interferon alpha-17 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL162420.13. On Mar 24, 2010 this sequence version replaced NM_021268.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: M11026.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000413767.2/ ENSP00000411940.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCCCTGT CCTTTTCTTT ACTGATGGCC GTGCTGGTGC TCAGCTACAA ATCCATCTGT 
TCTCTAGGCT GTGATCTGCC TCAGACCCAC AGCCTGGGTA ATAGGAGGGC CTTGATACTC 
CTGGCACAAA TGGGAAGAAT CTCTCCTTTC TCCTGCCTGA AGGACAGACA TGACTTTGGA 
CTTCCCCAGG AGGAGTTTGA TGGCAACCAG TTCCAGAAGA CTCAAGCCAT CTCTGTCCTC 
CATGAGATGA TCCAGCAGAC CTTCAATCTC TTCAGCACAG AGGACTCATC TGCTGCTTGG 
GAACAGAGCC TCCTAGAAAA ATTTTCCACT GAACTTTACC AGCAACTGAA TAACCTGGAA 
GCATGTGTGA TACAGGAGGT TGGGATGGAA GAGACTCCCC TGATGAATGA GGACTCCATC 
CTGGCTGTGA GGAAATACTT CCAAAGAATC ACTCTTTATC TAACAGAGAA GAAATACAGC 
CCTTGTGCCT GGGAGGTTGT CAGAGCAGAA ATCATGAGAT CTCTCTCTTT TTCAACAAAC 
TTGCAAAAAA TATTAAGGAG GAAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067091.1
CDS	50..619
Translation	MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFGLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKILRRKD

Target ORF information:

RefSeq Version	NM_021268.2
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon alpha 17 (IFNA17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021268.2

ORF Insert Sequence:

ATGGCCCTGT CCTTTTCTTT ACTGATGGCC GTGCTGGTGC TCAGCTACAA ATCCATCTGT 
TCTCTAGGCT GTGATCTGCC TCAGACCCAC AGCCTGGGTA ATAGGAGGGC CTTGATACTC 
CTGGCACAAA TGGGAAGAAT CTCTCCTTTC TCCTGCCTGA AGGACAGACA TGACTTTGGA 
CTTCCCCAGG AGGAGTTTGA TGGCAACCAG TTCCAGAAGA CTCAAGCCAT CTCTGTCCTC 
CATGAGATGA TCCAGCAGAC CTTCAATCTC TTCAGCACAG AGGACTCATC TGCTGCTTGG 
GAACAGAGCC TCCTAGAAAA ATTTTCCACT GAACTTTACC AGCAACTGAA TAACCTGGAA 
GCATGTGTGA TACAGGAGGT TGGGATGGAA GAGACTCCCC TGATGAATGA GGACTCCATC 
CTGGCTGTGA GGAAATACTT CCAAAGAATC ACTCTTTATC TAACAGAGAA GAAATACAGC 
CCTTGTGCCT GGGAGGTTGT CAGAGCAGAA ATCATGAGAT CTCTCTCTTT TTCAACAAAC 
TTGCAAAAAA TATTAAGGAG GAAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.
Familial cancer9(4)625-33(2010 Dec)
Yang XR,Liang X,Pfeiffer RM,Wheeler W,Maeder D,Burdette L,Yeager M,Chanock S,Tucker MA,Goldstein AM

Dengue hemorrhagic fever is associated with polymorphisms in JAK1.
European journal of human genetics : EJHG18(11)1221-7(2010 Nov)
Silva LK,Blanton RE,Parrado AR,Melo PS,Morato VG,Reis EA,Dias JP,Castro JM,Vasconcelos PF,Goddard KA,Barreto ML,Reis MG,Teixeira MG

Cystic fibrosis conductance regulator, tumor necrosis factor, interferon alpha-10, interferon alpha-17, and interferon gamma genotyping as potential risk markers in pulmonary sarcoidosis pathogenesis in Greek patients.
Genetic testing and molecular biomarkers14(4)577-84(2010 Aug)
Makrythanasis P,Tzetis M,Rapti A,Papatheodorou A,Tsipi M,Kitsiou S,Tsiamouri A,Poulou M,Roussos C,Kanavakis E

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.
The Journal of infectious diseases201(9)1371-80(2010 May)
Mosbruger TL,Duggal P,Goedert JJ,Kirk GD,Hoots WK,Tobler LH,Busch M,Peters MG,Rosen HR,Thomas DL,Thio CL

Efficient expression in Escherichia coli of two species of human interferon-alpha and their hybrid molecules.
DNA (Mary Ann Liebert, Inc.)4(3)221-32(1985 Jun)
Mizoguchi J,Pitha PM,Raj NB