HOXD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HOXD1
Entrez Gene ID	3231
Full Name	homeobox D1
Synonyms	HOX4,HOX4G,Hox-4.7
General protein information	Preferred Names homeobox D1 Names homeobox protein Hox-D1 homeo box 4G homeo box D1 homeobox protein Hox-GG
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q31.1
Summary	This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008].
Disorder MIM:	142987

mRNA and Protein(s)

mRNA	Protein	Name
XM_005246507.3	XP_005246564.1	homeobox protein Hox-D1 isoform X1
NM_024501.2	NP_078777.1	homeobox protein Hox-D1
NM_024501.3	NP_078777.1	homeobox protein Hox-D1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Hoxd1	NP_001099354.1
Mus musculus (house mouse)	Hoxd1	NP_034597.2
Pan troglodytes (chimpanzee)	HOXD1	XP_001144367.2
Canis lupus familiaris (dog)	HOXD1	XP_852467.3
Xenopus tropicalis (tropical clawed frog)	hoxd1	NP_001016678.1
Homo sapiens (human)	HOXD1	NP_078777.1
Bos taurus (cattle)	HOXD1	XP_002685353.1

Gene Ontology
Bibliography

Related articles in PubMed

Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties.
Swaminathan S, Hu X, Zheng X, Kriga Y, Shetty J, Zhao Y, Stephens R, Tran B, Baseler MW, Yang J, Lempicki RA, Huang D, Lane HC, Imamichi T
Biochemical and biophysical research communications434(2)228-34(2013 May)

Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.
Faryna M, Konermann C, Aulmann S, Bermejo JL, Brugger M, Diederichs S, Rom J, Weichenhan D, Claus R, Rehli M, Schirmacher P, Sinn HP, Plass C, Gerhauser C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology26(12)4937-50(2012 Dec)

Homeobox D1 regulates angiogenic functions of endothelial cells via integrin ?1 expression.
Park H, Choi HJ, Kim J, Kim M, Rho SS, Hwang D, Kim YM, Kwon YG
Biochemical and biophysical research communications408(1)186-92(2011 Apr)

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
Goode EL, Chenevix-Trench G, Song H, Ramus SJ, Notaridou M, Lawrenson K, Widschwendter M, Vierkant RA, Larson MC, Kjaer SK, Birrer MJ, Berchuck A, Schildkraut J, Tomlinson I, Kiemeney LA, Cook LS, Gronwald J, Garcia-Closas M, Gore ME, Campbell I, Whittemore AS, Sutphen R, Phelan C, Anton-Culver H, Pearce CL, Lambrechts D, Rossing MA, Chang-Claude J, Moysich KB, Goodman MT, D?rk T, Nevanlinna H, Ness RB, Rafnar T, Hogdall C, Hogdall E, Fridley BL, Cunningham JM, Sieh W, McGuire V, Godwin AK, Cramer DW, Hernandez D, Levine D, Lu K, Iversen ES, Palmieri RT, Houlston R, van Altena AM, Aben KK, Massuger LF, Brooks-Wilson A, Kelemen LE, Le ND, Jakubowska A, Lubinski J, Medrek K, Stafford A, Easton DF, Tyrer J, Bolton KL, Harrington P, Eccles D, Chen A, Molina AN, Davila BN, Arango H, Tsai YY, Chen Z, Risch HA, McLaughlin J, Narod SA, Ziogas A, Brewster W, Gentry-Maharaj A, Menon U, Wu AH, Stram DO, Pike MC, , Beesley J, Webb PM, , , , Chen X, Ekici AB, Thiel FC, Beckmann MW, Yang H, Wentzensen N, Lissowska J, Fasching PA, Despierre E, Amant F, Vergote I, Doherty J, Hein R, Wang-Gohrke S, Lurie G, Carney ME, Thompson PJ, Runnebaum I, Hillemanns P, D?rst M, Antonenkova N, Bogdanova N, Leminen A, Butzow R, Heikkinen T, Stefansson K, Sulem P, Besenbacher S, Sellers TA, Gayther SA, Pharoah PD,
Nature genetics42(10)874-9(2010 Oct)

Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.
Ester AR, Weymouth KS, Burt A, Wise CA, Scott A, Gurnett CA, Dobbs MB, Blanton SH, Hecht JT
American journal of medical genetics. Part A149A(12)2745-52(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that median methylation levels of BCAN, HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.
Title: Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.

HOXD1 plays a significant role in endothelial cells functions by regulating the expression of ITGB1.
Title: Homeobox D1 regulates angiogenic functions of endothelial cells via integrin ?1 expression.

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

Observational study of gene-disease association. (HuGE Navigator)
Title: High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.

The following HOXD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HOXD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55999	NM_024501.3 Latest version!	Homo sapiens homeobox D1 (HOXD1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu36174	XM_005246507.3 Latest version!	Homo sapiens homeobox D1 (HOXD1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu55999	NM_024501.2	Homo sapiens homeobox D1 (HOXD1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HOXD1 ( NM_024501.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078777.1 Homo sapiens homeobox D1 (HOXD1), mRNA.

Price & Availability↑

CloneID	OHu55999
Clone ID Related Accession (Same CDS sequence)	NM_024501.2 , NM_024501.3
Accession Version	NM_024501.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	homeobox protein Hox-D1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF241528.1 and BC014477.1. On Nov 22, 2018 this sequence version replaced NM_024501.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF241528.1, SRR1660803.20725.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000331462.6/ ENSP00000328598.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCTCCT ACCTGGAGTA CGTGTCATGC AGCAGCAGCG GCGGGGTCGG CGGCGACGTG 
CTCAGCTTGG CACCCAAGTT CTGCCGCTCC GACGCCCGGC CCGTGGCTCT GCAGCCCGCC 
TTCCCTCTGG GCAACGGCGA CGGCGCCTTC GTCAGCTGTC TGCCCCTGGC CGCCGCCCGA 
CCCTCGCCTT CGCCCCCGGC CGCCCCCGCG CGGCCGTCCG TACCGCCTCC GGCCGCGCCC 
CAGTACGCGC AGTGCACCCT GGAGGGGGCC TACGAACCTG GTGCCGCACC TGCCGCGGCA 
GCTGGGGGCG CGGACTACGG CTTCCTGGGG TCCGGGCCGG CGTACGACTT CCCGGGCGTG 
CTGGGGCGGG CGGCCGACGA CGGCGGGTCT CACGTCCACT ACGCCACCTC GGCCGTCTTC 
TCGGGCGGCG GCTCTTTCCT CCTCAGCGGC CAGGTGGATT ACGCGGCCTT CGGCGAACCC 
GGCCCTTTTC CGGCTTGTCT CAAAGCGTCA GCCGACGGCC ACCCTGGTGC TTTCCAGACC 
GCATCCCCGG CCCCAGGCAC CTACCCCAAG TCCGTCTCTC CCGCCTCCGG CCTCCCTGCC 
GCCTTCAGCA CGTTCGAGTG GATGAAAGTG AAGAGGAATG CCTCTAAGAA AGGCAAACTC 
GCCGAGTATG GGGCCGCTAG CCCCTCCAGC GCGATCCGCA CGAATTTCAG CACCAAGCAA 
CTGACAGAAC TGGAAAAAGA GTTTCATTTC AATAAGTACT TAACTCGAGC CCGGCGCATC 
GAGATAGCCA ACTGCTTGCA CCTGAATGAC ACGCAAGTCA AAATCTGGTT CCAGAACCGC 
AGGATGAAAC AGAAGAAAAG GGAACGAGAA GGGCTTCTGG CCACGGCCAT TCCTGTGGCT 
CCCCTCCAAC TTCCCCTCTC TGGAACAACC CCCACTAAGT TTATCAAGAA CCCCGGCAGC 
CCTTCTCAGT CCCAAGAGCC TTCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078777.1
CDS	135..1121
Translation	MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVAPLQLPLSGTTPTKFIKNPGSPSQSQEPS

Target ORF information:

RefSeq Version	NM_024501.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeobox D1 (HOXD1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024501.3

ORF Insert Sequence:

ATGAGCTCCT ACCTGGAGTA CGTGTCATGC AGCAGCAGCG GCGGGGTCGG CGGCGACGTG 
CTCAGCTTGG CACCCAAGTT CTGCCGCTCC GACGCCCGGC CCGTGGCTCT GCAGCCCGCC 
TTCCCTCTGG GCAACGGCGA CGGCGCCTTC GTCAGCTGTC TGCCCCTGGC CGCCGCCCGA 
CCCTCGCCTT CGCCCCCGGC CGCCCCCGCG CGGCCGTCCG TACCGCCTCC GGCCGCGCCC 
CAGTACGCGC AGTGCACCCT GGAGGGGGCC TACGAACCTG GTGCCGCACC TGCCGCGGCA 
GCTGGGGGCG CGGACTACGG CTTCCTGGGG TCCGGGCCGG CGTACGACTT CCCGGGCGTG 
CTGGGGCGGG CGGCCGACGA CGGCGGGTCT CACGTCCACT ACGCCACCTC GGCCGTCTTC 
TCGGGCGGCG GCTCTTTCCT CCTCAGCGGC CAGGTGGATT ACGCGGCCTT CGGCGAACCC 
GGCCCTTTTC CGGCTTGTCT CAAAGCGTCA GCCGACGGCC ACCCTGGTGC TTTCCAGACC 
GCATCCCCGG CCCCAGGCAC CTACCCCAAG TCCGTCTCTC CCGCCTCCGG CCTCCCTGCC 
GCCTTCAGCA CGTTCGAGTG GATGAAAGTG AAGAGGAATG CCTCTAAGAA AGGCAAACTC 
GCCGAGTATG GGGCCGCTAG CCCCTCCAGC GCGATCCGCA CGAATTTCAG CACCAAGCAA 
CTGACAGAAC TGGAAAAAGA GTTTCATTTC AATAAGTACT TAACTCGAGC CCGGCGCATC 
GAGATAGCCA ACTGCTTGCA CCTGAATGAC ACGCAAGTCA AAATCTGGTT CCAGAACCGC 
AGGATGAAAC AGAAGAAAAG GGAACGAGAA GGGCTTCTGG CCACGGCCAT TCCTGTGGCT 
CCCCTCCAAC TTCCCCTCTC TGGAACAACC CCCACTAAGT TTATCAAGAA CCCCGGCAGC 
CCTTCTCAGT CCCAAGAGCC TTCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOXD1 ( NM_024501.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_078777.1 Homo sapiens homeobox D1 (HOXD1), mRNA.

Price & Availability↑

CloneID	OHu55999
Clone ID Related Accession (Same CDS sequence)	NM_024501.2 , NM_024501.3
Accession Version	NM_024501.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	homeobox protein Hox-D1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF241528.1 and BC014477.1. On Aug 2, 2012 this sequence version replaced NM_024501.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF241528.1, SRR1660803.20725.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCTCCT ACCTGGAGTA CGTGTCATGC AGCAGCAGCG GCGGGGTCGG CGGCGACGTG 
CTCAGCTTGG CACCCAAGTT CTGCCGCTCC GACGCCCGGC CCGTGGCTCT GCAGCCCGCC 
TTCCCTCTGG GCAACGGCGA CGGCGCCTTC GTCAGCTGTC TGCCCCTGGC CGCCGCCCGA 
CCCTCGCCTT CGCCCCCGGC CGCCCCCGCG CGGCCGTCCG TACCGCCTCC GGCCGCGCCC 
CAGTACGCGC AGTGCACCCT GGAGGGGGCC TACGAACCTG GTGCCGCACC TGCCGCGGCA 
GCTGGGGGCG CGGACTACGG CTTCCTGGGG TCCGGGCCGG CGTACGACTT CCCGGGCGTG 
CTGGGGCGGG CGGCCGACGA CGGCGGGTCT CACGTCCACT ACGCCACCTC GGCCGTCTTC 
TCGGGCGGCG GCTCTTTCCT CCTCAGCGGC CAGGTGGATT ACGCGGCCTT CGGCGAACCC 
GGCCCTTTTC CGGCTTGTCT CAAAGCGTCA GCCGACGGCC ACCCTGGTGC TTTCCAGACC 
GCATCCCCGG CCCCAGGCAC CTACCCCAAG TCCGTCTCTC CCGCCTCCGG CCTCCCTGCC 
GCCTTCAGCA CGTTCGAGTG GATGAAAGTG AAGAGGAATG CCTCTAAGAA AGGCAAACTC 
GCCGAGTATG GGGCCGCTAG CCCCTCCAGC GCGATCCGCA CGAATTTCAG CACCAAGCAA 
CTGACAGAAC TGGAAAAAGA GTTTCATTTC AATAAGTACT TAACTCGAGC CCGGCGCATC 
GAGATAGCCA ACTGCTTGCA CCTGAATGAC ACGCAAGTCA AAATCTGGTT CCAGAACCGC 
AGGATGAAAC AGAAGAAAAG GGAACGAGAA GGGCTTCTGG CCACGGCCAT TCCTGTGGCT 
CCCCTCCAAC TTCCCCTCTC TGGAACAACC CCCACTAAGT TTATCAAGAA CCCCGGCAGC 
CCTTCTCAGT CCCAAGAGCC TTCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078777.1
CDS	224..1210
Translation	MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVAPLQLPLSGTTPTKFIKNPGSPSQSQEPS

Target ORF information:

RefSeq Version	NM_024501.2
Organism	Homo sapiens(human)
Definition	Homo sapiens homeobox D1 (HOXD1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024501.2

ORF Insert Sequence:

ATGAGCTCCT ACCTGGAGTA CGTGTCATGC AGCAGCAGCG GCGGGGTCGG CGGCGACGTG 
CTCAGCTTGG CACCCAAGTT CTGCCGCTCC GACGCCCGGC CCGTGGCTCT GCAGCCCGCC 
TTCCCTCTGG GCAACGGCGA CGGCGCCTTC GTCAGCTGTC TGCCCCTGGC CGCCGCCCGA 
CCCTCGCCTT CGCCCCCGGC CGCCCCCGCG CGGCCGTCCG TACCGCCTCC GGCCGCGCCC 
CAGTACGCGC AGTGCACCCT GGAGGGGGCC TACGAACCTG GTGCCGCACC TGCCGCGGCA 
GCTGGGGGCG CGGACTACGG CTTCCTGGGG TCCGGGCCGG CGTACGACTT CCCGGGCGTG 
CTGGGGCGGG CGGCCGACGA CGGCGGGTCT CACGTCCACT ACGCCACCTC GGCCGTCTTC 
TCGGGCGGCG GCTCTTTCCT CCTCAGCGGC CAGGTGGATT ACGCGGCCTT CGGCGAACCC 
GGCCCTTTTC CGGCTTGTCT CAAAGCGTCA GCCGACGGCC ACCCTGGTGC TTTCCAGACC 
GCATCCCCGG CCCCAGGCAC CTACCCCAAG TCCGTCTCTC CCGCCTCCGG CCTCCCTGCC 
GCCTTCAGCA CGTTCGAGTG GATGAAAGTG AAGAGGAATG CCTCTAAGAA AGGCAAACTC 
GCCGAGTATG GGGCCGCTAG CCCCTCCAGC GCGATCCGCA CGAATTTCAG CACCAAGCAA 
CTGACAGAAC TGGAAAAAGA GTTTCATTTC AATAAGTACT TAACTCGAGC CCGGCGCATC 
GAGATAGCCA ACTGCTTGCA CCTGAATGAC ACGCAAGTCA AAATCTGGTT CCAGAACCGC 
AGGATGAAAC AGAAGAAAAG GGAACGAGAA GGGCTTCTGG CCACGGCCAT TCCTGTGGCT 
CCCCTCCAAC TTCCCCTCTC TGGAACAACC CCCACTAAGT TTATCAAGAA CCCCGGCAGC 
CCTTCTCAGT CCCAAGAGCC TTCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOXD1 ( XM_005246507.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005246564.1 Homo sapiens homeobox D1 (HOXD1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu36174
Clone ID Related Accession (Same CDS sequence)	XM_005246507.3
Accession Version	XM_005246507.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	homeobox protein Hox-D1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005246507.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTCCT ACCTGGAGTA CGTGTCATGC AGCAGCAGCG GCGGGGTCGG CGGCGACGTG 
CTCAGCTTGG CACCCAAGTT CTGCCGCTCC GACGCCCGGC CCGTGGCTCT GCAGCCCGCC 
TTCCCTCTGG GCAACGGCGA CGGCGCCTTC GTCAGCTGTC TGCCCCTGGC CGCCGCCCGA 
CCCTCGCCTT CGCCCCCGGC CGCCCCCGCG CGGCCGTCCG TACCGCCTCC GGCCGCGCCC 
CAGTACGCGC AGTGCACCCT GGAGGGGGCC TACGAACCTG GTGCCGCACC TGCCGCGGCA 
GCTGGGGGCG CGGACTACGG CTTCCTGGGG TCCGGGCCGG CGTACGACTT CCCGGGCGTG 
CTGGGGCGGG CGGCCGACGA CGGCGGGTCT CACGTCCACT ACGCCACCTC GGCCGTCTTC 
TCGGGCGGCG GCTCTTTCCT CCTCAGCGGC CAGGTGGATT ACGCGGCCTT CGGCGAACCC 
GGCCCTTTTC CGGCTTGTCT CAAAGCGTCA GCCGACGGCC ACCCTGGTGC TTTCCAGACC 
GCATCCCCGG CCCCAGGCAC CTACCCCAAG TCCGTCTCTC CCGCCTCCGG CCTCCCTGCC 
GCCTTCAGCA CGTTCGAGTG GATGAAAGTG AAGAGGAATG CCTCTAAGAA AGACAGCGGT 
TTGGGTTTTG TGGAGGAGAC GCGTTCCCGG GCGAATTCCA TGGAGTCTGC CTCGAGTACA 
GATTCGGAAA ATGTGCCAGG CATTGAGAAA ATTTCAGGAA GGAGCTCTCC GTGGAACTTC 
TCCTGGCAAA CTCGCCGAGT ATGGGGCCGC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005246564.1
CDS	132..944
Translation	MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKDSGLGFVEETRSRANSMESASSTDSENVPGIEKISGRSSPWNFSWQTRRVWGR

Target ORF information:

RefSeq Version	XM_005246507.3
Organism	Homo sapiens(human)
Definition	Homo sapiens homeobox D1 (HOXD1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005246507.3

ORF Insert Sequence:

ATGAGCTCCT ACCTGGAGTA CGTGTCATGC AGCAGCAGCG GCGGGGTCGG CGGCGACGTG 
CTCAGCTTGG CACCCAAGTT CTGCCGCTCC GACGCCCGGC CCGTGGCTCT GCAGCCCGCC 
TTCCCTCTGG GCAACGGCGA CGGCGCCTTC GTCAGCTGTC TGCCCCTGGC CGCCGCCCGA 
CCCTCGCCTT CGCCCCCGGC CGCCCCCGCG CGGCCGTCCG TACCGCCTCC GGCCGCGCCC 
CAGTACGCGC AGTGCACCCT GGAGGGGGCC TACGAACCTG GTGCCGCACC TGCCGCGGCA 
GCTGGGGGCG CGGACTACGG CTTCCTGGGG TCCGGGCCGG CGTACGACTT CCCGGGCGTG 
CTGGGGCGGG CGGCCGACGA CGGCGGGTCT CACGTCCACT ACGCCACCTC GGCCGTCTTC 
TCGGGCGGCG GCTCTTTCCT CCTCAGCGGC CAGGTGGATT ACGCGGCCTT CGGCGAACCC 
GGCCCTTTTC CGGCTTGTCT CAAAGCGTCA GCCGACGGCC ACCCTGGTGC TTTCCAGACC 
GCATCCCCGG CCCCAGGCAC CTACCCCAAG TCCGTCTCTC CCGCCTCCGG CCTCCCTGCC 
GCCTTCAGCA CGTTCGAGTG GATGAAAGTG AAGAGGAATG CCTCTAAGAA AGACAGCGGT 
TTGGGTTTTG TGGAGGAGAC GCGTTCCCGG GCGAATTCCA TGGAGTCTGC CTCGAGTACA 
GATTCGGAAA ATGTGCCAGG CATTGAGAAA ATTTCAGGAA GGAGCTCTCC GTGGAACTTC 
TCCTGGCAAA CTCGCCGAGT ATGGGGCCGC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties.
Biochemical and biophysical research communications434(2)228-34(2013 May)
Swaminathan S,Hu X,Zheng X,Kriga Y,Shetty J,Zhao Y,Stephens R,Tran B,Baseler MW,Yang J,Lempicki RA,Huang D,Lane HC,Imamichi T

Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology26(12)4937-50(2012 Dec)
Faryna M,Konermann C,Aulmann S,Bermejo JL,Brugger M,Diederichs S,Rom J,Weichenhan D,Claus R,Rehli M,Schirmacher P,Sinn HP,Plass C,Gerhauser C

Homeobox D1 regulates angiogenic functions of endothelial cells via integrin ?1 expression.
Biochemical and biophysical research communications408(1)186-92(2011 Apr)
Park H,Choi HJ,Kim J,Kim M,Rho SS,Hwang D,Kim YM,Kwon YG

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
Nature genetics42(10)874-9(2010 Oct)
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Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.
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HOXD1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

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ORF Insert Sequence:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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