PLA2G4F cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLA2G4F
Entrez Gene ID	255189
Full Name	phospholipase A2 group IVF
Synonyms	PLA2G4FZ
General protein information	Preferred Names phospholipase A2 group IVF Names cytosolic phospholipase A2 zeta cPLA2-zeta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q15.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_213600.3	NP_998765.3	cytosolic phospholipase A2 zeta precursor
NM_213600.4	NP_998765.3	cytosolic phospholipase A2 zeta precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PLA2G4F	XP_510329.2
Mus musculus (house mouse)	Pla2g4f	NP_001019316.1
Rattus norvegicus (Norway rat)	Pla2g4f	XP_006234872.1
Gallus gallus (chicken)	PLA2G4F	XP_426428.2
Homo sapiens (human)	PLA2G4F	NP_998765.3
	PLA2G4F	XP_001102615.2
Bos taurus (cattle)	PLA2G4F	NP_001179498.1
Canis lupus familiaris (dog)	PLA2G4F	XP_005638347.1
Danio rerio (zebrafish)	LOC798864	XP_001920867.2
Danio rerio (zebrafish)	LOC565386	XP_693755.4
Xenopus tropicalis (tropical clawed frog)	pla2g4f	XP_002932885.2

Gene Ontology
Bibliography

Related articles in PubMed

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
Deng X, Sabino EC, Cunha-Neto E, Ribeiro AL, Ianni B, Mady C, Busch MP, Seielstad M,
PloS one8(11)e79629(2013)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, , ,
American journal of human genetics85(5)628-42(2009 Nov)

Analysis of the DNA sequence and duplication history of human chromosome 15.
Zody MC, Garber M, Sharpe T, Young SK, Rowen L, O'Neill K, Whittaker CA, Kamal M, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Kodira CD, Madan A, Qin S, Yang X, Abbasi N, Abouelleil A, Arachchi HM, Baradarani L, Birditt B, Bloom S, Bloom T, Borowsky ML, Burke J, Butler J, Cook A, DeArellano K, DeCaprio D, Dorris L 3rd, Dors M, Eichler EE, Engels R, Fahey J, Fleetwood P, Friedman C, Gearin G, Hall JL, Hensley G, Johnson E, Jones C, Kamat A, Kaur A, Locke DP, Madan A, Munson G, Jaffe DB, Lui A, Macdonald P, Mauceli E, Naylor JW, Nesbitt R, Nicol R, O'Leary SB, Ratcliffe A, Rounsley S, She X, Sneddon KM, Stewart S, Sougnez C, Stone SM, Topham K, Vincent D, Wang S, Zimmer AR, Birren BW, Hood L, Lander ES, Nusbaum C
Nature440(7084)671-5(2006 Mar)

Identification of novel cytosolic phospholipase A(2)s, murine cPLA(2){delta}, {epsilon}, and {zeta}, which form a gene cluster with cPLA(2){beta}.
Ohto T, Uozumi N, Hirabayashi T, Shimizu T
The Journal of biological chemistry280(26)24576-83(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following PLA2G4F gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLA2G4F cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12417	NM_213600.4 Latest version!	Homo sapiens phospholipase A2 group IVF (PLA2G4F), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu12417	NM_213600.3	Homo sapiens phospholipase A2 group IVF (PLA2G4F), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLA2G4F ( NM_213600.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_998765.3 Homo sapiens phospholipase A2 group IVF (PLA2G4F), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12417
Clone ID Related Accession (Same CDS sequence)	NM_213600.3 , NM_213600.4
Accession Version	NM_213600.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2550bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	cytosolic phospholipase A2 zeta precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK172836.1, BC142682.1 and AC036103.8. On Dec 18, 2009 this sequence version replaced NM_213600.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK304368.1, BC146648.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END##

ATGCTTTGGG CACTCTGGCC AAGGTGGCTG GCAGACAAGA TGCTGCCCCT CCTGGGGGCA 
GTGCTGCTTC AGAAGAGAGA GAAGAGGGGC CCTCTGTGGA GGCACTGGCG GCGGGAAACC 
TACCCATACT ATGACCTCCA GGTGAAGGTG CTGAGGGCCA CAAACATCCG GGGCACAGAC 
CTGCTGTCCA AAGCCGACTG CTATGTGCAA CTGTGGCTGC CCACGGCGTC CCCAAGCCCT 
GCCCAGACTA GGATAGTGGC CAACTGCAGT GACCCCGAGT GGAATGAGAC CTTCCACTAC 
CAGATCCATG GTGCTGTGAA GAACGTCCTG GAGCTCACCC TCTATGACAA GGACATCCTG 
GGCAGCGACC AGCTCTCTCT GCTCCTGTTT GACCTGAGAA GCCTCAAGTG TGGCCAACCT 
CACAAACACA CCTTCCCACT CAACCACCAG GATTCACAAG AGCTGCAGGT GGAATTTGTT 
CTGGAGAAGA GCCAGGTGCC TGCATCTGAA GTCATCACCA ACGGGGTTCT GGTGGCTCAC 
CCCTGTCTGA GAATCCAGGG CACGCTCCGG GGAGATGGGA CAGCCCCACG GGAAGAGTAC 
GGCTCTAGGC AGCTCCAGCT GGCAGTGCCT GGAGCCTACG AGAAGCCACA GCTCTTGCCC 
CTGCAGCCTC CCACAGAGCC AGGCCTCCCA CCCACCTTTA CCTTCCACGT GAACCCAGTG 
CTGAGCTCCA GGCTACACGT GGAGCTGATG GAGCTGCTGG CAGCTGTGCA GAGTGGCCCC 
AGCGCAGAGT TGGAGGCTCA GACCAGCAAG CTGGGCGAGG GGGGCATCCT GCTCTCCTCT 
CTGCCCCTAG GCCAGGAGGA ACAGTGTTCT GTGGCCCTGG GGGAGGGCCA GGAGGTGGCT 
CTGAGCATGA AGGTGGAAAT GAGCTCCGGG GACCTAGACC TACGCCTTGG CTTTGACCTC 
TCTGACGGGG AGCAGGAGTT TCTGGACAGG AGGAAGCAGG TCGTGTCCAA GGCCCTGCAG 
CAAGTGCTGG GATTGAGTGA GGCTCTGGAC AGTGGCCAGG TGCCTGTAGT GGCTGTGTTG 
GGTTCCGGGG GTGGAACCCG AGCCATGTCT TCTCTGTACG GCAGCCTGGC AGGGTTGCAG 
GAGCTCGGCC TTCTAGACAC TGTGACCTAC CTGAGTGGGG TCTCTGGGTC TACCTGGTGC 
ATCTCCACAC TCTACAGGGA CCCAGCCTGG TCCCAGGTGG CCTTGCAGGG CCCCATTGAG 
CGTGCCCAGG TTCACGTCTG CAGCAGTAAG ATGGGAGCTT TGTCCACGGA GCGGCTACAG 
TACTACACTC AGGAACTGGG GGTCCGGGAG CGCAGTGGCC ACAGCGTGTC CCTCATCGAC 
CTCTGGGGCC TCCTTGTTGA GTATCTCCTG TACCAGGAGG AGAACCCTGC CAAGCTGTCT 
GACCAACAGG AGGCGGTCCG CCAGGGTCAG AACCCTTACC CCATTTACAC CAGTGTCAAC 
GTCCGCACCA ACTTGAGTGG GGAAGATTTT GCAGAGTGGT GCGAGTTCAC GCCCTATGAG 
GTTGGCTTCC CCAAGTACGG GGCTTATGTT CCCACCGAGC TCTTCGGCTC AGAACTCTTC 
ATGGGACGAT TGCTGCAGCT CCAGCCTGAA CCCCGGATCT GTTACCTGCA AGGTATGTGG 
GGCAGCGCCT TTGCCACCAG CCTGGATGAG ATCTTCCTAA AGACCGCCGG CTCGGGCCTC 
AGCTTCCTGG AGTGGTACAG AGGCAGTGTG AATATCACAG ACGACTGCCA GAAGCCTCAG 
CTGCACAACC CCTCGAGGCT GCGAACGAGG CTCCTCACCC CACAGGGGCC CTTCTCCCAG 
GCTGTGCTGG ACATATTCAC CTCCCGCTTC ACTTCCGCCC AGAGCTTTAA CTTCACCCGG 
GGTCTCTGCT TGCACAAGGA CTATGTGGCT GGCAGGGAGT TCGTGGCCTG GAAAGACACA 
CACCCGGACG CCTTCCCCAA CCAGCTCACC CCCATGCGGG ACTGCCTGTA CCTGGTGGAC 
GGAGGCTTTG CCATCAACTC TCCGTTCCCA CTGGCTCTGC TGCCTCAGAG AGCAGTGGAC 
CTCATTCTGT CCTTTGACTA TTCCTTGGAA GCCCCTTTTG AGGTCTTGAA GATGACAGAG 
AAGTACTGCC TGGACCGAGG AATCCCCTTC CCTAGCATCG AGGTGGGCCC TGAGGACATG 
GAGGAGGCCC GTGAGTGCTA TCTGTTTGCC AAGGCTGAGG ACCCCCGCTC CCCCATTGTG 
CTGCACTTCC CCCTGGTTAA CCGTACCTTC CGCACACACC TGGCCCCAGG TGTGGAGCGA 
CAAACAGCTG AGGAGAAGGC CTTTGGGGAC TTTGTCATCA ACAGGCCAGA CACCCCCTAT 
GGCATGATGA ACTTCACCTA TGAGCCCCAG GACTTTTATC GGCTGGTGGC CCTCAGTCGA 
TACAACGTCC TGAACAACGT GGAGACCTTG AAGTGCGCCC TCCAGCTGGC TCTGGACCGG 
CACCAGGCTC GGGAGAGGGC AGGGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998765.3
CDS	93..2642
Translation	MLWALWPRWLADKMLPLLGAVLLQKREKRGPLWRHWRRETYPYYDLQVKVLRATNIRGTDLLSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGAVKNVLELTLYDKDILGSDQLSLLLFDLRSLKCGQPHKHTFPLNHQDSQELQVEFVLEKSQVPASEVITNGVLVAHPCLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEKPQLLPLQPPTEPGLPPTFTFHVNPVLSSRLHVELMELLAAVQSGPSAELEAQTSKLGEGGILLSSLPLGQEEQCSVALGEGQEVALSMKVEMSSGDLDLRLGFDLSDGEQEFLDRRKQVVSKALQQVLGLSEALDSGQVPVVAVLGSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYRDPAWSQVALQGPIERAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLWGLLVEYLLYQEENPAKLSDQQEAVRQGQNPYPIYTSVNVRTNLSGEDFAEWCEFTPYEVGFPKYGAYVPTELFGSELFMGRLLQLQPEPRICYLQGMWGSAFATSLDEIFLKTAGSGLSFLEWYRGSVNITDDCQKPQLHNPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRGLCLHKDYVAGREFVAWKDTHPDAFPNQLTPMRDCLYLVDGGFAINSPFPLALLPQRAVDLILSFDYSLEAPFEVLKMTEKYCLDRGIPFPSIEVGPEDMEEARECYLFAKAEDPRSPIVLHFPLVNRTFRTHLAPGVERQTAEEKAFGDFVINRPDTPYGMMNFTYEPQDFYRLVALSRYNVLNNVETLKCALQLALDRHQARERAGA

Target ORF information:

RefSeq Version	NM_213600.3
Organism	Homo sapiens(human)
Definition	Homo sapiens phospholipase A2 group IVF (PLA2G4F), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213600.3

ORF Insert Sequence:

ATGCTTTGGG CACTCTGGCC AAGGTGGCTG GCAGACAAGA TGCTGCCCCT CCTGGGGGCA 
GTGCTGCTTC AGAAGAGAGA GAAGAGGGGC CCTCTGTGGA GGCACTGGCG GCGGGAAACC 
TACCCATACT ATGACCTCCA GGTGAAGGTG CTGAGGGCCA CAAACATCCG GGGCACAGAC 
CTGCTGTCCA AAGCCGACTG CTATGTGCAA CTGTGGCTGC CCACGGCGTC CCCAAGCCCT 
GCCCAGACTA GGATAGTGGC CAACTGCAGT GACCCCGAGT GGAATGAGAC CTTCCACTAC 
CAGATCCATG GTGCTGTGAA GAACGTCCTG GAGCTCACCC TCTATGACAA GGACATCCTG 
GGCAGCGACC AGCTCTCTCT GCTCCTGTTT GACCTGAGAA GCCTCAAGTG TGGCCAACCT 
CACAAACACA CCTTCCCACT CAACCACCAG GATTCACAAG AGCTGCAGGT GGAATTTGTT 
CTGGAGAAGA GCCAGGTGCC TGCATCTGAA GTCATCACCA ACGGGGTTCT GGTGGCTCAC 
CCCTGTCTGA GAATCCAGGG CACGCTCCGG GGAGATGGGA CAGCCCCACG GGAAGAGTAC 
GGCTCTAGGC AGCTCCAGCT GGCAGTGCCT GGAGCCTACG AGAAGCCACA GCTCTTGCCC 
CTGCAGCCTC CCACAGAGCC AGGCCTCCCA CCCACCTTTA CCTTCCACGT GAACCCAGTG 
CTGAGCTCCA GGCTACACGT GGAGCTGATG GAGCTGCTGG CAGCTGTGCA GAGTGGCCCC 
AGCGCAGAGT TGGAGGCTCA GACCAGCAAG CTGGGCGAGG GGGGCATCCT GCTCTCCTCT 
CTGCCCCTAG GCCAGGAGGA ACAGTGTTCT GTGGCCCTGG GGGAGGGCCA GGAGGTGGCT 
CTGAGCATGA AGGTGGAAAT GAGCTCCGGG GACCTAGACC TACGCCTTGG CTTTGACCTC 
TCTGACGGGG AGCAGGAGTT TCTGGACAGG AGGAAGCAGG TCGTGTCCAA GGCCCTGCAG 
CAAGTGCTGG GATTGAGTGA GGCTCTGGAC AGTGGCCAGG TGCCTGTAGT GGCTGTGTTG 
GGTTCCGGGG GTGGAACCCG AGCCATGTCT TCTCTGTACG GCAGCCTGGC AGGGTTGCAG 
GAGCTCGGCC TTCTAGACAC TGTGACCTAC CTGAGTGGGG TCTCTGGGTC TACCTGGTGC 
ATCTCCACAC TCTACAGGGA CCCAGCCTGG TCCCAGGTGG CCTTGCAGGG CCCCATTGAG 
CGTGCCCAGG TTCACGTCTG CAGCAGTAAG ATGGGAGCTT TGTCCACGGA GCGGCTACAG 
TACTACACTC AGGAACTGGG GGTCCGGGAG CGCAGTGGCC ACAGCGTGTC CCTCATCGAC 
CTCTGGGGCC TCCTTGTTGA GTATCTCCTG TACCAGGAGG AGAACCCTGC CAAGCTGTCT 
GACCAACAGG AGGCGGTCCG CCAGGGTCAG AACCCTTACC CCATTTACAC CAGTGTCAAC 
GTCCGCACCA ACTTGAGTGG GGAAGATTTT GCAGAGTGGT GCGAGTTCAC GCCCTATGAG 
GTTGGCTTCC CCAAGTACGG GGCTTATGTT CCCACCGAGC TCTTCGGCTC AGAACTCTTC 
ATGGGACGAT TGCTGCAGCT CCAGCCTGAA CCCCGGATCT GTTACCTGCA AGGTATGTGG 
GGCAGCGCCT TTGCCACCAG CCTGGATGAG ATCTTCCTAA AGACCGCCGG CTCGGGCCTC 
AGCTTCCTGG AGTGGTACAG AGGCAGTGTG AATATCACAG ACGACTGCCA GAAGCCTCAG 
CTGCACAACC CCTCGAGGCT GCGAACGAGG CTCCTCACCC CACAGGGGCC CTTCTCCCAG 
GCTGTGCTGG ACATATTCAC CTCCCGCTTC ACTTCCGCCC AGAGCTTTAA CTTCACCCGG 
GGTCTCTGCT TGCACAAGGA CTATGTGGCT GGCAGGGAGT TCGTGGCCTG GAAAGACACA 
CACCCGGACG CCTTCCCCAA CCAGCTCACC CCCATGCGGG ACTGCCTGTA CCTGGTGGAC 
GGAGGCTTTG CCATCAACTC TCCGTTCCCA CTGGCTCTGC TGCCTCAGAG AGCAGTGGAC 
CTCATTCTGT CCTTTGACTA TTCCTTGGAA GCCCCTTTTG AGGTCTTGAA GATGACAGAG 
AAGTACTGCC TGGACCGAGG AATCCCCTTC CCTAGCATCG AGGTGGGCCC TGAGGACATG 
GAGGAGGCCC GTGAGTGCTA TCTGTTTGCC AAGGCTGAGG ACCCCCGCTC CCCCATTGTG 
CTGCACTTCC CCCTGGTTAA CCGTACCTTC CGCACACACC TGGCCCCAGG TGTGGAGCGA 
CAAACAGCTG AGGAGAAGGC CTTTGGGGAC TTTGTCATCA ACAGGCCAGA CACCCCCTAT 
GGCATGATGA ACTTCACCTA TGAGCCCCAG GACTTTTATC GGCTGGTGGC CCTCAGTCGA 
TACAACGTCC TGAACAACGT GGAGACCTTG AAGTGCGCCC TCCAGCTGGC TCTGGACCGG 
CACCAGGCTC GGGAGAGGGC AGGGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLA2G4F ( NM_213600.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_998765.3 Homo sapiens phospholipase A2 group IVF (PLA2G4F), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12417
Clone ID Related Accession (Same CDS sequence)	NM_213600.3 , NM_213600.4
Accession Version	NM_213600.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2550bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	cytosolic phospholipase A2 zeta precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK172836.1, BC142682.1 and AC036103.8. On May 17, 2019 this sequence version replaced NM_213600.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK304368.1, BC142682.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000397272.7/ ENSP00000380442.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCTTTGGG CACTCTGGCC AAGGTGGCTG GCAGACAAGA TGCTGCCCCT CCTGGGGGCA 
GTGCTGCTTC AGAAGAGAGA GAAGAGGGGC CCTCTGTGGA GGCACTGGCG GCGGGAAACC 
TACCCATACT ATGACCTCCA GGTGAAGGTG CTGAGGGCCA CAAACATCCG GGGCACAGAC 
CTGCTGTCCA AAGCCGACTG CTATGTGCAA CTGTGGCTGC CCACGGCGTC CCCAAGCCCT 
GCCCAGACTA GGATAGTGGC CAACTGCAGT GACCCCGAGT GGAATGAGAC CTTCCACTAC 
CAGATCCATG GTGCTGTGAA GAACGTCCTG GAGCTCACCC TCTATGACAA GGACATCCTG 
GGCAGCGACC AGCTCTCTCT GCTCCTGTTT GACCTGAGAA GCCTCAAGTG TGGCCAACCT 
CACAAACACA CCTTCCCACT CAACCACCAG GATTCACAAG AGCTGCAGGT GGAATTTGTT 
CTGGAGAAGA GCCAGGTGCC TGCATCTGAA GTCATCACCA ACGGGGTTCT GGTGGCTCAC 
CCCTGTCTGA GAATCCAGGG CACGCTCCGG GGAGATGGGA CAGCCCCACG GGAAGAGTAC 
GGCTCTAGGC AGCTCCAGCT GGCAGTGCCT GGAGCCTACG AGAAGCCACA GCTCTTGCCC 
CTGCAGCCTC CCACAGAGCC AGGCCTCCCA CCCACCTTTA CCTTCCACGT GAACCCAGTG 
CTGAGCTCCA GGCTACACGT GGAGCTGATG GAGCTGCTGG CAGCTGTGCA GAGTGGCCCC 
AGCGCAGAGT TGGAGGCTCA GACCAGCAAG CTGGGCGAGG GGGGCATCCT GCTCTCCTCT 
CTGCCCCTAG GCCAGGAGGA ACAGTGTTCT GTGGCCCTGG GGGAGGGCCA GGAGGTGGCT 
CTGAGCATGA AGGTGGAAAT GAGCTCCGGG GACCTAGACC TACGCCTTGG CTTTGACCTC 
TCTGACGGGG AGCAGGAGTT TCTGGACAGG AGGAAGCAGG TCGTGTCCAA GGCCCTGCAG 
CAAGTGCTGG GATTGAGTGA GGCTCTGGAC AGTGGCCAGG TGCCTGTAGT GGCTGTGTTG 
GGTTCCGGGG GTGGAACCCG AGCCATGTCT TCTCTGTACG GCAGCCTGGC AGGGTTGCAG 
GAGCTCGGCC TTCTAGACAC TGTGACCTAC CTGAGTGGGG TCTCTGGGTC TACCTGGTGC 
ATCTCCACAC TCTACAGGGA CCCAGCCTGG TCCCAGGTGG CCTTGCAGGG CCCCATTGAG 
CGTGCCCAGG TTCACGTCTG CAGCAGTAAG ATGGGAGCTT TGTCCACGGA GCGGCTACAG 
TACTACACTC AGGAACTGGG GGTCCGGGAG CGCAGTGGCC ACAGCGTGTC CCTCATCGAC 
CTCTGGGGCC TCCTTGTTGA GTATCTCCTG TACCAGGAGG AGAACCCTGC CAAGCTGTCT 
GACCAACAGG AGGCGGTCCG CCAGGGTCAG AACCCTTACC CCATTTACAC CAGTGTCAAC 
GTCCGCACCA ACTTGAGTGG GGAAGATTTT GCAGAGTGGT GCGAGTTCAC GCCCTATGAG 
GTTGGCTTCC CCAAGTACGG GGCTTATGTT CCCACCGAGC TCTTCGGCTC AGAACTCTTC 
ATGGGACGAT TGCTGCAGCT CCAGCCTGAA CCCCGGATCT GTTACCTGCA AGGTATGTGG 
GGCAGCGCCT TTGCCACCAG CCTGGATGAG ATCTTCCTAA AGACCGCCGG CTCGGGCCTC 
AGCTTCCTGG AGTGGTACAG AGGCAGTGTG AATATCACAG ACGACTGCCA GAAGCCTCAG 
CTGCACAACC CCTCGAGGCT GCGAACGAGG CTCCTCACCC CACAGGGGCC CTTCTCCCAG 
GCTGTGCTGG ACATATTCAC CTCCCGCTTC ACTTCCGCCC AGAGCTTTAA CTTCACCCGG 
GGTCTCTGCT TGCACAAGGA CTATGTGGCT GGCAGGGAGT TCGTGGCCTG GAAAGACACA 
CACCCGGACG CCTTCCCCAA CCAGCTCACC CCCATGCGGG ACTGCCTGTA CCTGGTGGAC 
GGAGGCTTTG CCATCAACTC TCCGTTCCCA CTGGCTCTGC TGCCTCAGAG AGCAGTGGAC 
CTCATTCTGT CCTTTGACTA TTCCTTGGAA GCCCCTTTTG AGGTCTTGAA GATGACAGAG 
AAGTACTGCC TGGACCGAGG AATCCCCTTC CCTAGCATCG AGGTGGGCCC TGAGGACATG 
GAGGAGGCCC GTGAGTGCTA TCTGTTTGCC AAGGCTGAGG ACCCCCGCTC CCCCATTGTG 
CTGCACTTCC CCCTGGTTAA CCGTACCTTC CGCACACACC TGGCCCCAGG TGTGGAGCGA 
CAAACAGCTG AGGAGAAGGC CTTTGGGGAC TTTGTCATCA ACAGGCCAGA CACCCCCTAT 
GGCATGATGA ACTTCACCTA TGAGCCCCAG GACTTTTATC GGCTGGTGGC CCTCAGTCGA 
TACAACGTCC TGAACAACGT GGAGACCTTG AAGTGCGCCC TCCAGCTGGC TCTGGACCGG 
CACCAGGCTC GGGAGAGGGC AGGGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998765.3
CDS	88..2637
Translation	MLWALWPRWLADKMLPLLGAVLLQKREKRGPLWRHWRRETYPYYDLQVKVLRATNIRGTDLLSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGAVKNVLELTLYDKDILGSDQLSLLLFDLRSLKCGQPHKHTFPLNHQDSQELQVEFVLEKSQVPASEVITNGVLVAHPCLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEKPQLLPLQPPTEPGLPPTFTFHVNPVLSSRLHVELMELLAAVQSGPSAELEAQTSKLGEGGILLSSLPLGQEEQCSVALGEGQEVALSMKVEMSSGDLDLRLGFDLSDGEQEFLDRRKQVVSKALQQVLGLSEALDSGQVPVVAVLGSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYRDPAWSQVALQGPIERAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLWGLLVEYLLYQEENPAKLSDQQEAVRQGQNPYPIYTSVNVRTNLSGEDFAEWCEFTPYEVGFPKYGAYVPTELFGSELFMGRLLQLQPEPRICYLQGMWGSAFATSLDEIFLKTAGSGLSFLEWYRGSVNITDDCQKPQLHNPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRGLCLHKDYVAGREFVAWKDTHPDAFPNQLTPMRDCLYLVDGGFAINSPFPLALLPQRAVDLILSFDYSLEAPFEVLKMTEKYCLDRGIPFPSIEVGPEDMEEARECYLFAKAEDPRSPIVLHFPLVNRTFRTHLAPGVERQTAEEKAFGDFVINRPDTPYGMMNFTYEPQDFYRLVALSRYNVLNNVETLKCALQLALDRHQARERAGA

Target ORF information:

RefSeq Version	NM_213600.4
Organism	Homo sapiens(human)
Definition	Homo sapiens phospholipase A2 group IVF (PLA2G4F), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213600.4

ORF Insert Sequence:

ATGCTTTGGG CACTCTGGCC AAGGTGGCTG GCAGACAAGA TGCTGCCCCT CCTGGGGGCA 
GTGCTGCTTC AGAAGAGAGA GAAGAGGGGC CCTCTGTGGA GGCACTGGCG GCGGGAAACC 
TACCCATACT ATGACCTCCA GGTGAAGGTG CTGAGGGCCA CAAACATCCG GGGCACAGAC 
CTGCTGTCCA AAGCCGACTG CTATGTGCAA CTGTGGCTGC CCACGGCGTC CCCAAGCCCT 
GCCCAGACTA GGATAGTGGC CAACTGCAGT GACCCCGAGT GGAATGAGAC CTTCCACTAC 
CAGATCCATG GTGCTGTGAA GAACGTCCTG GAGCTCACCC TCTATGACAA GGACATCCTG 
GGCAGCGACC AGCTCTCTCT GCTCCTGTTT GACCTGAGAA GCCTCAAGTG TGGCCAACCT 
CACAAACACA CCTTCCCACT CAACCACCAG GATTCACAAG AGCTGCAGGT GGAATTTGTT 
CTGGAGAAGA GCCAGGTGCC TGCATCTGAA GTCATCACCA ACGGGGTTCT GGTGGCTCAC 
CCCTGTCTGA GAATCCAGGG CACGCTCCGG GGAGATGGGA CAGCCCCACG GGAAGAGTAC 
GGCTCTAGGC AGCTCCAGCT GGCAGTGCCT GGAGCCTACG AGAAGCCACA GCTCTTGCCC 
CTGCAGCCTC CCACAGAGCC AGGCCTCCCA CCCACCTTTA CCTTCCACGT GAACCCAGTG 
CTGAGCTCCA GGCTACACGT GGAGCTGATG GAGCTGCTGG CAGCTGTGCA GAGTGGCCCC 
AGCGCAGAGT TGGAGGCTCA GACCAGCAAG CTGGGCGAGG GGGGCATCCT GCTCTCCTCT 
CTGCCCCTAG GCCAGGAGGA ACAGTGTTCT GTGGCCCTGG GGGAGGGCCA GGAGGTGGCT 
CTGAGCATGA AGGTGGAAAT GAGCTCCGGG GACCTAGACC TACGCCTTGG CTTTGACCTC 
TCTGACGGGG AGCAGGAGTT TCTGGACAGG AGGAAGCAGG TCGTGTCCAA GGCCCTGCAG 
CAAGTGCTGG GATTGAGTGA GGCTCTGGAC AGTGGCCAGG TGCCTGTAGT GGCTGTGTTG 
GGTTCCGGGG GTGGAACCCG AGCCATGTCT TCTCTGTACG GCAGCCTGGC AGGGTTGCAG 
GAGCTCGGCC TTCTAGACAC TGTGACCTAC CTGAGTGGGG TCTCTGGGTC TACCTGGTGC 
ATCTCCACAC TCTACAGGGA CCCAGCCTGG TCCCAGGTGG CCTTGCAGGG CCCCATTGAG 
CGTGCCCAGG TTCACGTCTG CAGCAGTAAG ATGGGAGCTT TGTCCACGGA GCGGCTACAG 
TACTACACTC AGGAACTGGG GGTCCGGGAG CGCAGTGGCC ACAGCGTGTC CCTCATCGAC 
CTCTGGGGCC TCCTTGTTGA GTATCTCCTG TACCAGGAGG AGAACCCTGC CAAGCTGTCT 
GACCAACAGG AGGCGGTCCG CCAGGGTCAG AACCCTTACC CCATTTACAC CAGTGTCAAC 
GTCCGCACCA ACTTGAGTGG GGAAGATTTT GCAGAGTGGT GCGAGTTCAC GCCCTATGAG 
GTTGGCTTCC CCAAGTACGG GGCTTATGTT CCCACCGAGC TCTTCGGCTC AGAACTCTTC 
ATGGGACGAT TGCTGCAGCT CCAGCCTGAA CCCCGGATCT GTTACCTGCA AGGTATGTGG 
GGCAGCGCCT TTGCCACCAG CCTGGATGAG ATCTTCCTAA AGACCGCCGG CTCGGGCCTC 
AGCTTCCTGG AGTGGTACAG AGGCAGTGTG AATATCACAG ACGACTGCCA GAAGCCTCAG 
CTGCACAACC CCTCGAGGCT GCGAACGAGG CTCCTCACCC CACAGGGGCC CTTCTCCCAG 
GCTGTGCTGG ACATATTCAC CTCCCGCTTC ACTTCCGCCC AGAGCTTTAA CTTCACCCGG 
GGTCTCTGCT TGCACAAGGA CTATGTGGCT GGCAGGGAGT TCGTGGCCTG GAAAGACACA 
CACCCGGACG CCTTCCCCAA CCAGCTCACC CCCATGCGGG ACTGCCTGTA CCTGGTGGAC 
GGAGGCTTTG CCATCAACTC TCCGTTCCCA CTGGCTCTGC TGCCTCAGAG AGCAGTGGAC 
CTCATTCTGT CCTTTGACTA TTCCTTGGAA GCCCCTTTTG AGGTCTTGAA GATGACAGAG 
AAGTACTGCC TGGACCGAGG AATCCCCTTC CCTAGCATCG AGGTGGGCCC TGAGGACATG 
GAGGAGGCCC GTGAGTGCTA TCTGTTTGCC AAGGCTGAGG ACCCCCGCTC CCCCATTGTG 
CTGCACTTCC CCCTGGTTAA CCGTACCTTC CGCACACACC TGGCCCCAGG TGTGGAGCGA 
CAAACAGCTG AGGAGAAGGC CTTTGGGGAC TTTGTCATCA ACAGGCCAGA CACCCCCTAT 
GGCATGATGA ACTTCACCTA TGAGCCCCAG GACTTTTATC GGCTGGTGGC CCTCAGTCGA 
TACAACGTCC TGAACAACGT GGAGACCTTG AAGTGCGCCC TCCAGCTGGC TCTGGACCGG 
CACCAGGCTC GGGAGAGGGC AGGGGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
PloS one8(11)e79629(2013)
Deng X,Sabino EC,Cunha-Neto E,Ribeiro AL,Ianni B,Mady C,Busch MP,Seielstad M,

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics85(5)628-42(2009 Nov)
Talmud PJ,Drenos F,Shah S,Shah T,Palmen J,Verzilli C,Gaunt TR,Pallas J,Lovering R,Li K,Casas JP,Sofat R,Kumari M,Rodriguez S,Johnson T,Newhouse SJ,Dominiczak A,Samani NJ,Caulfield M,Sever P,Stanton A,Shields DC,Padmanabhan S,Melander O,Hastie C,Delles C,Ebrahim S,Marmot MG,Smith GD,Lawlor DA,Munroe PB,Day IN,Kivimaki M,Whittaker J,Humphries SE,Hingorani AD,,,

Analysis of the DNA sequence and duplication history of human chromosome 15.
Nature440(7084)671-5(2006 Mar)
Zody MC,Garber M,Sharpe T,Young SK,Rowen L,O'Neill K,Whittaker CA,Kamal M,Chang JL,Cuomo CA,Dewar K,FitzGerald MG,Kodira CD,Madan A,Qin S,Yang X,Abbasi N,Abouelleil A,Arachchi HM,Baradarani L,Birditt B,Bloom S,Bloom T,Borowsky ML,Burke J,Butler J,Cook A,DeArellano K,DeCaprio D,Dorris L 3rd,Dors M,Eichler EE,Engels R,Fahey J,Fleetwood P,Friedman C,Gearin G,Hall JL,Hensley G,Johnson E,Jones C,Kamat A,Kaur A,Locke DP,Madan A,Munson G,Jaffe DB,Lui A,Macdonald P,Mauceli E,Naylor JW,Nesbitt R,Nicol R,O'Leary SB,Ratcliffe A,Rounsley S,She X,Sneddon KM,Stewart S,Sougnez C,Stone SM,Topham K,Vincent D,Wang S,Zimmer AR,Birren BW,Hood L,Lander ES,Nusbaum C

Identification of novel cytosolic phospholipase A(2)s, murine cPLA(2){delta}, {epsilon}, and {zeta}, which form a gene cluster with cPLA(2){beta}.
The Journal of biological chemistry280(26)24576-83(2005 Jul)
Ohto T,Uozumi N,Hirabayashi T,Shimizu T