BRINP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BRINP1
Entrez Gene ID	1620
Full Name	BMP/retinoic acid inducible neural specific 1
Synonyms	DBC1,DBCCR1,FAM5A
General protein information	Preferred Names BMP/retinoic acid inducible neural specific 1 Names BMP/retinoic acid-inducible neural-specific protein 1 bA574M5.1 (deleted in bladder cancer chromosome region candidate 1 (IB3089A)) bone morphogenetic protein/retinoic acid inducible neural-specific 1 bone morphogenic protein/retinoic acid inducible neural-specific 1 deleted in bladder cancer 1 deleted in bladder cancer chromosome region candidate 1 deleted in bladder cancer protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q33.1
Summary	This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers. [provided by RefSeq, Jul 2008].
Disorder MIM:	602865

mRNA and Protein(s)

mRNA	Protein	Name
NM_014618.2	NP_055433.2	BMP/retinoic acid-inducible neural-specific protein 1 precursor
NM_014618.3	NP_055433.2	BMP/retinoic acid-inducible neural-specific protein 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	BRINP1	NP_055433.2
Bos taurus (cattle)	BRINP1	NP_001015669.1
	DBC1	XP_002800043.1
Danio rerio (zebrafish)	LOC100334375	XP_002662264.3
Mus musculus (house mouse)	Brinp1	NP_064351.2
Xenopus tropicalis (tropical clawed frog)	dbc1	XP_002935252.2
Pan troglodytes (chimpanzee)	DBC1	XP_520219.2
Canis lupus familiaris (dog)	BRINP1	XP_538815.2
Rattus norvegicus (Norway rat)	Brinp1	NP_536730.1
Gallus gallus (chicken)	BRINP1	NP_989780.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of DBCCR1 as a suppressor in the development of lung cancer that is associated with increased DNA methyltransferase 1.
Zhou G, Ye J, Fang Y, Zhang Z, Zhang J, Sun L, Feng J
Oncotarget8(20)32821-32832(2017 May)

DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erb?.
Chini CC, Escande C, Nin V, Chini EN
The Biochemical journal451(3)453-61(2013 May)

The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response.
Raynes R, Pombier KM, Nguyen K, Brunquell J, Mendez JE, Westerheide SD
PloS one8(1)e54364(2013)

Regulation of SIRT1 activity by genotoxic stress.
Yuan J, Luo K, Liu T, Lou Z
Genes & development26(8)791-6(2012 Apr)

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.
Close P, East P, Dirac-Svejstrup AB, Hartmann H, Heron M, Maslen S, Chariot A, S?ding J, Skehel M, Svejstrup JQ
Nature484(7394)386-9(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DBC1 modulates the stability and function of the nuclear receptor Rev-erb-alpha.
Title: DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erb?.

we found that the SIRT1 modulators AROS and DBC1 have an impact on hsp70 transcription, HSF1 acetylation status, and HSF1 recruitment to the hsp70 promoter
Title: The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response.

the stress-induced DBC1-SIRT1 interaction is important for cell fate determination following genotoxic stress.
Title: Regulation of SIRT1 activity by genotoxic stress.

Rxpression of DBC1 and SIRT1 is a significant prognostic indicator for breast carcinoma patients.
Title: Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma.

High DBC1 expression is associated with breast and lung cancer..
Title: Deleted in breast cancer 1 (DBC1) is a dynamically regulated protein.

The following BRINP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BRINP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30795	NM_014618.3 Latest version!	Homo sapiens BMP/retinoic acid inducible neural specific 1 (BRINP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
View Old Accession Versions >>
OHu30795	NM_014618.2	Homo sapiens BMP/retinoic acid inducible neural specific 1 (BRINP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BRINP1 ( NM_014618.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055433.2 Homo sapiens BMP/retinoic acid inducible neural specific 1 (BRINP1), mRNA.

Price & Availability↑

CloneID	OHu30795
Clone ID Related Accession (Same CDS sequence)	NM_014618.2 , NM_014618.3
Accession Version	NM_014618.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2286bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	BMP/retinoic acid-inducible neural-specific protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL138894.11, BC065196.1 and Z41452.1. On Jun 1, 2007 this sequence version replaced NM_014618.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF027734.1, SRR1803611.118999.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTGGA GGTTTGTTGA GCTCCTCTAC TTCCTGTTTA TATGGGGCCG TATCTCAGTG 
CAGCCCTCCC ACCAGGAACC AGCTGGGACA GACCAACATG TCTCCAAGGA ATTTGATTGG 
CTCATTTCAG ACAGGGGGCC TTTCCACCAC TCCAGGAGCT ACCTATCCTT TGTGGAAAGA 
CACCGTCAAG GATTTACAAC CAGATATAAA ATATACAGGG AGTTTGCCCG TTGGAAGGTG 
AGGAACACAG CCATCGAGAG GAGAGATCTG GTCCGCCATC CAGTGCCCCT CATGCCGGAG 
TTTCAAAGGA GCATCCGCCT GCTTGGCAGG AGACCTACCA CTCAGCAGTT CATCGATACC 
ATCATCAAAA AGTACGGCAC CCACCTGCTC ATCTCAGCCA CATTGGGAGG GGAGGAGGCT 
TTGACCATGT ATATGGACAA AAGTCGCCTC GACAGGAAGT CAGGGAATGC CACTCAAAGT 
GTTGAAGCTC TGCACCAGCT CGCATCATCC TACTTTGTTG ACCGTGATGG TACCATGAGG 
AGGCTTCATG AGATCCAGAT ATCAACTGGA GCAATCAAGG TCACAGAGAC ACGCACTGGG 
CCTCTGGGCT GTAACAGCTA TGACAATCTG GACTCTGTGA GTTCCGTCCT TCTGCAAAGC 
ACGGAGAGCA AACTGCACCT TCAAGGTCTT CAGATAATCT TTCCTCAGTA TCTGCAAGAG 
AAGTTTGTCC AGTCGGCCTT GAGCTATATC ATGTGCAATG GGGAGGGGGA GTACCTGTGC 
CAGAACAGCC AGTGTCGCTG CCAATGTGCC GAGGAGTTTC CGCAGTGCAA CTGCCCCATC 
ACGGACATCC AGATCATGGA GTACACGCTG GCCAACATGG CCAAGTCTTG GGCCGAAGCT 
TATAAGGACC TGGAGAATTC AGATGAGTTT AAATCATTTA TGAAGCGCCT CCCCAGCAAC 
CACTTCCTGA CCATCGGAAG CATCCATCAG CACTGGGGCA ATGACTGGGA CCTGCAGAAC 
CGCTACAAGC TCCTGCAGAG TGCCACGGAG GCACAGAGAC AAAAGATCCA ACGCACTGCC 
CGCAAGCTTT TCGGCCTCAG TGTACGCTGT CGCCACAATC CCAACCACCA GCTGCCTAGA 
GAGAGGACAA TTCAGCAGTG GCTTGCAAGG GTCCAGTCAC TCCTCTACTG TAATGAGAAT 
GGGTTTTGGG GAACCTTCCT GGAGAGCCAG CGGAGCTGCG TGTGCCACGG CAGCACCACG 
CTGTGCCAGC GCCCCATCCC CTGCGTGATA GGCGGGAACA ACAGCTGCGC CATGTGCAGC 
CTGGCCAACA TCTCCCTCTG CGGCTCCTGC AACAAGGGCT ACAAGCTGTA TCGAGGCCGC 
TGTGAACCAC AGAACGTGGA CTCGGAGCGG AGCGAGCAGT TCATCAGCTT TGAGACTGAC 
CTGGACTTCC AGGACCTGGA GCTGAAGTAC CTGCTGCAGA AGATGGACTC ACGCCTCTAC 
GTCCACACCA CCTTCATCAG CAACGAGATC CGCCTCGACA CCTTCTTTGA CCCTCGGTGG 
CGCAAGCGCA TGTCCCTCAC TCTCAAGAGC AACAAGAACC GCATGGACTT CATCCACATG 
GTGATCGGCA TGTCCATGCG CATCTGCCAG ATGCGCAACA GCAGCCTGGA CCCCATGTTC 
TTTGTCTATG TCAACCCCTT TAGCGGGAGC CATTCGGAGG GCTGGAACAT GCCCTTCGGG 
GAATTTGGCT ACCCACGCTG GGAGAAGATC CGTCTCCAAA ACAGCCAGTG CTACAACTGG 
ACTCTTTTGC TGGGCAATCG GTGGAAAACA TTTTTCGAGA CGGTCCACAT CTACCTACGT 
AGTCGGACTC GGCTACCTAC CCTACTGCGA AATGAGACTG GCCAGGGCCC CGTGGACCTG 
TCGGATCCCT CCAAGAGGCA GTTCTACATC AAGATCTCAG ACGTGCAGGT GTTTGGGTAT 
AGCCTGAGGT TCAACGCCGA CCTCCTGCGC AGTGCAGTGC AGCAGGTCAA CCAGTCCTAC 
ACACAGGGCG GCCAGTTCTA TTCCTCTTCG TCAGTGATGC TCCTCTTGTT GGATATTCGG 
GACCGAATTA ATCGCCTGGC CCCTCCTGTG GCCCCGGGGA AACCCCAGCT GGACTTGTTC 
TCCTGTATGC TGAAACACCG CCTGAAACTG ACCAACAGCG AGATCATCAG GGTGAACCAC 
GCCTTGGACC TGTACAACAC GGAGATCCTC AAACAGTCGG ACCAGATGAC AGCCAAACTC 
TGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055433.2
CDS	457..2742
Translation	MNWRFVELLYFLFIWGRISVQPSHQEPAGTDQHVSKEFDWLISDRGPFHHSRSYLSFVERHRQGFTTRYKIYREFARWKVRNTAIERRDLVRHPVPLMPEFQRSIRLLGRRPTTQQFIDTIIKKYGTHLLISATLGGEEALTMYMDKSRLDRKSGNATQSVEALHQLASSYFVDRDGTMRRLHEIQISTGAIKVTETRTGPLGCNSYDNLDSVSSVLLQSTESKLHLQGLQIIFPQYLQEKFVQSALSYIMCNGEGEYLCQNSQCRCQCAEEFPQCNCPITDIQIMEYTLANMAKSWAEAYKDLENSDEFKSFMKRLPSNHFLTIGSIHQHWGNDWDLQNRYKLLQSATEAQRQKIQRTARKLFGLSVRCRHNPNHQLPRERTIQQWLARVQSLLYCNENGFWGTFLESQRSCVCHGSTTLCQRPIPCVIGGNNSCAMCSLANISLCGSCNKGYKLYRGRCEPQNVDSERSEQFISFETDLDFQDLELKYLLQKMDSRLYVHTTFISNEIRLDTFFDPRWRKRMSLTLKSNKNRMDFIHMVIGMSMRICQMRNSSLDPMFFVYVNPFSGSHSEGWNMPFGEFGYPRWEKIRLQNSQCYNWTLLLGNRWKTFFETVHIYLRSRTRLPTLLRNETGQGPVDLSDPSKRQFYIKISDVQVFGYSLRFNADLLRSAVQQVNQSYTQGGQFYSSSSVMLLLLDIRDRINRLAPPVAPGKPQLDLFSCMLKHRLKLTNSEIIRVNHALDLYNTEILKQSDQMTAKLC

Target ORF information:

RefSeq Version	NM_014618.2
Organism	Homo sapiens(human)
Definition	Homo sapiens BMP/retinoic acid inducible neural specific 1 (BRINP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014618.2

ORF Insert Sequence:

ATGAACTGGA GGTTTGTTGA GCTCCTCTAC TTCCTGTTTA TATGGGGCCG TATCTCAGTG 
CAGCCCTCCC ACCAGGAACC AGCTGGGACA GACCAACATG TCTCCAAGGA ATTTGATTGG 
CTCATTTCAG ACAGGGGGCC TTTCCACCAC TCCAGGAGCT ACCTATCCTT TGTGGAAAGA 
CACCGTCAAG GATTTACAAC CAGATATAAA ATATACAGGG AGTTTGCCCG TTGGAAGGTG 
AGGAACACAG CCATCGAGAG GAGAGATCTG GTCCGCCATC CAGTGCCCCT CATGCCGGAG 
TTTCAAAGGA GCATCCGCCT GCTTGGCAGG AGACCTACCA CTCAGCAGTT CATCGATACC 
ATCATCAAAA AGTACGGCAC CCACCTGCTC ATCTCAGCCA CATTGGGAGG GGAGGAGGCT 
TTGACCATGT ATATGGACAA AAGTCGCCTC GACAGGAAGT CAGGGAATGC CACTCAAAGT 
GTTGAAGCTC TGCACCAGCT CGCATCATCC TACTTTGTTG ACCGTGATGG TACCATGAGG 
AGGCTTCATG AGATCCAGAT ATCAACTGGA GCAATCAAGG TCACAGAGAC ACGCACTGGG 
CCTCTGGGCT GTAACAGCTA TGACAATCTG GACTCTGTGA GTTCCGTCCT TCTGCAAAGC 
ACGGAGAGCA AACTGCACCT TCAAGGTCTT CAGATAATCT TTCCTCAGTA TCTGCAAGAG 
AAGTTTGTCC AGTCGGCCTT GAGCTATATC ATGTGCAATG GGGAGGGGGA GTACCTGTGC 
CAGAACAGCC AGTGTCGCTG CCAATGTGCC GAGGAGTTTC CGCAGTGCAA CTGCCCCATC 
ACGGACATCC AGATCATGGA GTACACGCTG GCCAACATGG CCAAGTCTTG GGCCGAAGCT 
TATAAGGACC TGGAGAATTC AGATGAGTTT AAATCATTTA TGAAGCGCCT CCCCAGCAAC 
CACTTCCTGA CCATCGGAAG CATCCATCAG CACTGGGGCA ATGACTGGGA CCTGCAGAAC 
CGCTACAAGC TCCTGCAGAG TGCCACGGAG GCACAGAGAC AAAAGATCCA ACGCACTGCC 
CGCAAGCTTT TCGGCCTCAG TGTACGCTGT CGCCACAATC CCAACCACCA GCTGCCTAGA 
GAGAGGACAA TTCAGCAGTG GCTTGCAAGG GTCCAGTCAC TCCTCTACTG TAATGAGAAT 
GGGTTTTGGG GAACCTTCCT GGAGAGCCAG CGGAGCTGCG TGTGCCACGG CAGCACCACG 
CTGTGCCAGC GCCCCATCCC CTGCGTGATA GGCGGGAACA ACAGCTGCGC CATGTGCAGC 
CTGGCCAACA TCTCCCTCTG CGGCTCCTGC AACAAGGGCT ACAAGCTGTA TCGAGGCCGC 
TGTGAACCAC AGAACGTGGA CTCGGAGCGG AGCGAGCAGT TCATCAGCTT TGAGACTGAC 
CTGGACTTCC AGGACCTGGA GCTGAAGTAC CTGCTGCAGA AGATGGACTC ACGCCTCTAC 
GTCCACACCA CCTTCATCAG CAACGAGATC CGCCTCGACA CCTTCTTTGA CCCTCGGTGG 
CGCAAGCGCA TGTCCCTCAC TCTCAAGAGC AACAAGAACC GCATGGACTT CATCCACATG 
GTGATCGGCA TGTCCATGCG CATCTGCCAG ATGCGCAACA GCAGCCTGGA CCCCATGTTC 
TTTGTCTATG TCAACCCCTT TAGCGGGAGC CATTCGGAGG GCTGGAACAT GCCCTTCGGG 
GAATTTGGCT ACCCACGCTG GGAGAAGATC CGTCTCCAAA ACAGCCAGTG CTACAACTGG 
ACTCTTTTGC TGGGCAATCG GTGGAAAACA TTTTTCGAGA CGGTCCACAT CTACCTACGT 
AGTCGGACTC GGCTACCTAC CCTACTGCGA AATGAGACTG GCCAGGGCCC CGTGGACCTG 
TCGGATCCCT CCAAGAGGCA GTTCTACATC AAGATCTCAG ACGTGCAGGT GTTTGGGTAT 
AGCCTGAGGT TCAACGCCGA CCTCCTGCGC AGTGCAGTGC AGCAGGTCAA CCAGTCCTAC 
ACACAGGGCG GCCAGTTCTA TTCCTCTTCG TCAGTGATGC TCCTCTTGTT GGATATTCGG 
GACCGAATTA ATCGCCTGGC CCCTCCTGTG GCCCCGGGGA AACCCCAGCT GGACTTGTTC 
TCCTGTATGC TGAAACACCG CCTGAAACTG ACCAACAGCG AGATCATCAG GGTGAACCAC 
GCCTTGGACC TGTACAACAC GGAGATCCTC AAACAGTCGG ACCAGATGAC AGCCAAACTC 
TGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BRINP1 ( NM_014618.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055433.2 Homo sapiens BMP/retinoic acid inducible neural specific 1 (BRINP1), mRNA.

Price & Availability↑

CloneID	OHu30795
Clone ID Related Accession (Same CDS sequence)	NM_014618.2 , NM_014618.3
Accession Version	NM_014618.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2286bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	BMP/retinoic acid-inducible neural-specific protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL138894.11, BC065196.1, Z41452.1 and AL353773.9. On Nov 22, 2018 this sequence version replaced NM_014618.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.100445.1, SRR1803617.54931.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265922.8/ ENSP00000265922.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAACTGGA GGTTTGTTGA GCTCCTCTAC TTCCTGTTTA TATGGGGCCG TATCTCAGTG 
CAGCCCTCCC ACCAGGAACC AGCTGGGACA GACCAACATG TCTCCAAGGA ATTTGATTGG 
CTCATTTCAG ACAGGGGGCC TTTCCACCAC TCCAGGAGCT ACCTATCCTT TGTGGAAAGA 
CACCGTCAAG GATTTACAAC CAGATATAAA ATATACAGGG AGTTTGCCCG TTGGAAGGTG 
AGGAACACAG CCATCGAGAG GAGAGATCTG GTCCGCCATC CAGTGCCCCT CATGCCGGAG 
TTTCAAAGGA GCATCCGCCT GCTTGGCAGG AGACCTACCA CTCAGCAGTT CATCGATACC 
ATCATCAAAA AGTACGGCAC CCACCTGCTC ATCTCAGCCA CATTGGGAGG GGAGGAGGCT 
TTGACCATGT ATATGGACAA AAGTCGCCTC GACAGGAAGT CAGGGAATGC CACTCAAAGT 
GTTGAAGCTC TGCACCAGCT CGCATCATCC TACTTTGTTG ACCGTGATGG TACCATGAGG 
AGGCTTCATG AGATCCAGAT ATCAACTGGA GCAATCAAGG TCACAGAGAC ACGCACTGGG 
CCTCTGGGCT GTAACAGCTA TGACAATCTG GACTCTGTGA GTTCCGTCCT TCTGCAAAGC 
ACGGAGAGCA AACTGCACCT TCAAGGTCTT CAGATAATCT TTCCTCAGTA TCTGCAAGAG 
AAGTTTGTCC AGTCGGCCTT GAGCTATATC ATGTGCAATG GGGAGGGGGA GTACCTGTGC 
CAGAACAGCC AGTGTCGCTG CCAATGTGCC GAGGAGTTTC CGCAGTGCAA CTGCCCCATC 
ACGGACATCC AGATCATGGA GTACACGCTG GCCAACATGG CCAAGTCTTG GGCCGAAGCT 
TATAAGGACC TGGAGAATTC AGATGAGTTT AAATCATTTA TGAAGCGCCT CCCCAGCAAC 
CACTTCCTGA CCATCGGAAG CATCCATCAG CACTGGGGCA ATGACTGGGA CCTGCAGAAC 
CGCTACAAGC TCCTGCAGAG TGCCACGGAG GCACAGAGAC AAAAGATCCA ACGCACTGCC 
CGCAAGCTTT TCGGCCTCAG TGTACGCTGT CGCCACAATC CCAACCACCA GCTGCCTAGA 
GAGAGGACAA TTCAGCAGTG GCTTGCAAGG GTCCAGTCAC TCCTCTACTG TAATGAGAAT 
GGGTTTTGGG GAACCTTCCT GGAGAGCCAG CGGAGCTGCG TGTGCCACGG CAGCACCACG 
CTGTGCCAGC GCCCCATCCC CTGCGTGATA GGCGGGAACA ACAGCTGCGC CATGTGCAGC 
CTGGCCAACA TCTCCCTCTG CGGCTCCTGC AACAAGGGCT ACAAGCTGTA TCGAGGCCGC 
TGTGAACCAC AGAACGTGGA CTCGGAGCGG AGCGAGCAGT TCATCAGCTT TGAGACTGAC 
CTGGACTTCC AGGACCTGGA GCTGAAGTAC CTGCTGCAGA AGATGGACTC ACGCCTCTAC 
GTCCACACCA CCTTCATCAG CAACGAGATC CGCCTCGACA CCTTCTTTGA CCCTCGGTGG 
CGCAAGCGCA TGTCCCTCAC TCTCAAGAGC AACAAGAACC GCATGGACTT CATCCACATG 
GTGATCGGCA TGTCCATGCG CATCTGCCAG ATGCGCAACA GCAGCCTGGA CCCCATGTTC 
TTTGTCTATG TCAACCCCTT TAGCGGGAGC CATTCGGAGG GCTGGAACAT GCCCTTCGGG 
GAATTTGGCT ACCCACGCTG GGAGAAGATC CGTCTCCAAA ACAGCCAGTG CTACAACTGG 
ACTCTTTTGC TGGGCAATCG GTGGAAAACA TTTTTCGAGA CGGTCCACAT CTACCTACGT 
AGTCGGACTC GGCTACCTAC CCTACTGCGA AATGAGACTG GCCAGGGCCC CGTGGACCTG 
TCGGATCCCT CCAAGAGGCA GTTCTACATC AAGATCTCAG ACGTGCAGGT GTTTGGGTAT 
AGCCTGAGGT TCAACGCCGA CCTCCTGCGC AGTGCAGTGC AGCAGGTCAA CCAGTCCTAC 
ACACAGGGCG GCCAGTTCTA TTCCTCTTCG TCAGTGATGC TCCTCTTGTT GGATATTCGG 
GACCGAATTA ATCGCCTGGC CCCTCCTGTG GCCCCGGGGA AACCCCAGCT GGACTTGTTC 
TCCTGTATGC TGAAACACCG CCTGAAACTG ACCAACAGCG AGATCATCAG GGTGAACCAC 
GCCTTGGACC TGTACAACAC GGAGATCCTC AAACAGTCGG ACCAGATGAC AGCCAAACTC 
TGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055433.2
CDS	431..2716
Translation	MNWRFVELLYFLFIWGRISVQPSHQEPAGTDQHVSKEFDWLISDRGPFHHSRSYLSFVERHRQGFTTRYKIYREFARWKVRNTAIERRDLVRHPVPLMPEFQRSIRLLGRRPTTQQFIDTIIKKYGTHLLISATLGGEEALTMYMDKSRLDRKSGNATQSVEALHQLASSYFVDRDGTMRRLHEIQISTGAIKVTETRTGPLGCNSYDNLDSVSSVLLQSTESKLHLQGLQIIFPQYLQEKFVQSALSYIMCNGEGEYLCQNSQCRCQCAEEFPQCNCPITDIQIMEYTLANMAKSWAEAYKDLENSDEFKSFMKRLPSNHFLTIGSIHQHWGNDWDLQNRYKLLQSATEAQRQKIQRTARKLFGLSVRCRHNPNHQLPRERTIQQWLARVQSLLYCNENGFWGTFLESQRSCVCHGSTTLCQRPIPCVIGGNNSCAMCSLANISLCGSCNKGYKLYRGRCEPQNVDSERSEQFISFETDLDFQDLELKYLLQKMDSRLYVHTTFISNEIRLDTFFDPRWRKRMSLTLKSNKNRMDFIHMVIGMSMRICQMRNSSLDPMFFVYVNPFSGSHSEGWNMPFGEFGYPRWEKIRLQNSQCYNWTLLLGNRWKTFFETVHIYLRSRTRLPTLLRNETGQGPVDLSDPSKRQFYIKISDVQVFGYSLRFNADLLRSAVQQVNQSYTQGGQFYSSSSVMLLLLDIRDRINRLAPPVAPGKPQLDLFSCMLKHRLKLTNSEIIRVNHALDLYNTEILKQSDQMTAKLC

Target ORF information:

RefSeq Version	NM_014618.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BMP/retinoic acid inducible neural specific 1 (BRINP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014618.3

ORF Insert Sequence:

ATGAACTGGA GGTTTGTTGA GCTCCTCTAC TTCCTGTTTA TATGGGGCCG TATCTCAGTG 
CAGCCCTCCC ACCAGGAACC AGCTGGGACA GACCAACATG TCTCCAAGGA ATTTGATTGG 
CTCATTTCAG ACAGGGGGCC TTTCCACCAC TCCAGGAGCT ACCTATCCTT TGTGGAAAGA 
CACCGTCAAG GATTTACAAC CAGATATAAA ATATACAGGG AGTTTGCCCG TTGGAAGGTG 
AGGAACACAG CCATCGAGAG GAGAGATCTG GTCCGCCATC CAGTGCCCCT CATGCCGGAG 
TTTCAAAGGA GCATCCGCCT GCTTGGCAGG AGACCTACCA CTCAGCAGTT CATCGATACC 
ATCATCAAAA AGTACGGCAC CCACCTGCTC ATCTCAGCCA CATTGGGAGG GGAGGAGGCT 
TTGACCATGT ATATGGACAA AAGTCGCCTC GACAGGAAGT CAGGGAATGC CACTCAAAGT 
GTTGAAGCTC TGCACCAGCT CGCATCATCC TACTTTGTTG ACCGTGATGG TACCATGAGG 
AGGCTTCATG AGATCCAGAT ATCAACTGGA GCAATCAAGG TCACAGAGAC ACGCACTGGG 
CCTCTGGGCT GTAACAGCTA TGACAATCTG GACTCTGTGA GTTCCGTCCT TCTGCAAAGC 
ACGGAGAGCA AACTGCACCT TCAAGGTCTT CAGATAATCT TTCCTCAGTA TCTGCAAGAG 
AAGTTTGTCC AGTCGGCCTT GAGCTATATC ATGTGCAATG GGGAGGGGGA GTACCTGTGC 
CAGAACAGCC AGTGTCGCTG CCAATGTGCC GAGGAGTTTC CGCAGTGCAA CTGCCCCATC 
ACGGACATCC AGATCATGGA GTACACGCTG GCCAACATGG CCAAGTCTTG GGCCGAAGCT 
TATAAGGACC TGGAGAATTC AGATGAGTTT AAATCATTTA TGAAGCGCCT CCCCAGCAAC 
CACTTCCTGA CCATCGGAAG CATCCATCAG CACTGGGGCA ATGACTGGGA CCTGCAGAAC 
CGCTACAAGC TCCTGCAGAG TGCCACGGAG GCACAGAGAC AAAAGATCCA ACGCACTGCC 
CGCAAGCTTT TCGGCCTCAG TGTACGCTGT CGCCACAATC CCAACCACCA GCTGCCTAGA 
GAGAGGACAA TTCAGCAGTG GCTTGCAAGG GTCCAGTCAC TCCTCTACTG TAATGAGAAT 
GGGTTTTGGG GAACCTTCCT GGAGAGCCAG CGGAGCTGCG TGTGCCACGG CAGCACCACG 
CTGTGCCAGC GCCCCATCCC CTGCGTGATA GGCGGGAACA ACAGCTGCGC CATGTGCAGC 
CTGGCCAACA TCTCCCTCTG CGGCTCCTGC AACAAGGGCT ACAAGCTGTA TCGAGGCCGC 
TGTGAACCAC AGAACGTGGA CTCGGAGCGG AGCGAGCAGT TCATCAGCTT TGAGACTGAC 
CTGGACTTCC AGGACCTGGA GCTGAAGTAC CTGCTGCAGA AGATGGACTC ACGCCTCTAC 
GTCCACACCA CCTTCATCAG CAACGAGATC CGCCTCGACA CCTTCTTTGA CCCTCGGTGG 
CGCAAGCGCA TGTCCCTCAC TCTCAAGAGC AACAAGAACC GCATGGACTT CATCCACATG 
GTGATCGGCA TGTCCATGCG CATCTGCCAG ATGCGCAACA GCAGCCTGGA CCCCATGTTC 
TTTGTCTATG TCAACCCCTT TAGCGGGAGC CATTCGGAGG GCTGGAACAT GCCCTTCGGG 
GAATTTGGCT ACCCACGCTG GGAGAAGATC CGTCTCCAAA ACAGCCAGTG CTACAACTGG 
ACTCTTTTGC TGGGCAATCG GTGGAAAACA TTTTTCGAGA CGGTCCACAT CTACCTACGT 
AGTCGGACTC GGCTACCTAC CCTACTGCGA AATGAGACTG GCCAGGGCCC CGTGGACCTG 
TCGGATCCCT CCAAGAGGCA GTTCTACATC AAGATCTCAG ACGTGCAGGT GTTTGGGTAT 
AGCCTGAGGT TCAACGCCGA CCTCCTGCGC AGTGCAGTGC AGCAGGTCAA CCAGTCCTAC 
ACACAGGGCG GCCAGTTCTA TTCCTCTTCG TCAGTGATGC TCCTCTTGTT GGATATTCGG 
GACCGAATTA ATCGCCTGGC CCCTCCTGTG GCCCCGGGGA AACCCCAGCT GGACTTGTTC 
TCCTGTATGC TGAAACACCG CCTGAAACTG ACCAACAGCG AGATCATCAG GGTGAACCAC 
GCCTTGGACC TGTACAACAC GGAGATCCTC AAACAGTCGG ACCAGATGAC AGCCAAACTC 
TGCTAA