SP7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SP7
Entrez Gene ID	121340
Full Name	Sp7 transcription factor
Synonyms	OI11,OI12,OSX,osterix
General protein information	Preferred Names Sp7 transcription factor Names transcription factor Sp7 zinc finger protein osterix
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.13
Summary	This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010].
Disorder MIM:	606633
Disorder Html:	?Osteogenesis imperfecta, type XII, 613849 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001300837.1	NP_001287766.1	transcription factor Sp7 isoform b
XM_011537900.2	XP_011536202.1	transcription factor Sp7 isoform X1
NM_152860.2	NP_690599.1	transcription factor Sp7 isoform a
NM_001173467.2	NP_001166938.1	transcription factor Sp7 isoform a
NM_001173467.3	NP_001166938.1	transcription factor Sp7 isoform a
NM_152860.1	NP_690599.1	transcription factor Sp7 isoform a

Pathways from BioSystems

Homologies

Homo sapiens (human)	SP7	NP_690599.1
Canis lupus familiaris (dog)	SP7	XP_849781.2
Pan troglodytes (chimpanzee)	SP7	XP_001138751.1
Bos taurus (cattle)	SP7	NP_001095612.1
Mus musculus (house mouse)	Sp7	NP_569725.1
Rattus norvegicus (Norway rat)	Sp7	NP_852039.2
Xenopus tropicalis (tropical clawed frog)	sp7	NP_001128590.1
Danio rerio (zebrafish)	sp7	NP_998028.1
	SP7	XP_001104653.1

Gene Ontology
Bibliography

Related articles in PubMed

MiR-96 regulates bone metabolism by targeting osterix.
Liu H, Liu Q, Wu XP, He HB, Fu L
Clinical and experimental pharmacology & physiology(2017 Dec)

Osterix Decreases the Chemosensitivity of Breast Cancer Cells by Upregulating GALNT14.
Wu J, Chen X, Bao Q, Duan R, Jin Y, Shui Y, Yao B, Lu X, Wang Y, Cui H, Li L, Yuan H, Ma C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology44(3)998-1010(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

dissection of these interconnected epigenetic mechanisms that govern Sp7 gene activation reveals a hierarchical process where regulatory components mediating DNA demethylation play a leading role
Title: Tet-Mediated DNA Demethylation Is Required for SWI/SNF-Dependent Chromatin Remodeling and Histone-Modifying Activities That Trigger Expression of the Sp7 Osteoblast Master Gene during Mesenchymal Lineage Commitment.

SP7 gene promoter is robustly enriched in epigenetic repressive marks that may explain its poor transcriptional response to osteoblast differentiating media in umbilical cord derived mesenchymal stem cells.
Title: Epigenetic Signatures at the RUNX2-P1 and Sp7 Gene Promoters Control Osteogenic Lineage Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells.

Eight and five of the nine samples were negative for cell adhesion molecule 1 and Osterix respectively. The other markers showed no statistical significance(CD151,ALP). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 could be a useful marker for identifying this phenomenon in carcinoma tissues
Title: Manifestation of osteoblastic phenotypes in the sarcomatous component of epithelial carcinoma and sarcomatoid carcinoma.

Osterix decreased the chemosensitivity of breast cancer cells by upregulating the expression of GALNT14, which eventually suppressed the apoptosis of breast cancer cells.
Title: Osterix Decreases the Chemosensitivity of Breast Cancer Cells by Upregulating GALNT14.

TP(thymidine phosphorylase ) curbed the expression of three proteins-IRF8, RUNX2, and osterix. This downregulation was epigenetically driven: High levels of 2DDR, a product of TP secreted by myeloma cells, activated PI3K/AKT signaling and increased the methyltransferase DNMT3A's expression
Title: Pinpointing a Factor in Myeloma Bone Disease.

The following SP7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SP7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19040	NM_152860.2 Latest version!	Homo sapiens Sp7 transcription factor (SP7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu19040	NM_001173467.3 Latest version!	Homo sapiens Sp7 transcription factor (SP7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu46319	NM_001300837.1 Latest version!	Homo sapiens Sp7 transcription factor (SP7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu46319	XM_011537900.2 Latest version!	Homo sapiens Sp7 transcription factor (SP7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu19040	NM_001173467.2	Homo sapiens Sp7 transcription factor (SP7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu19040	NM_152860.1	Homo sapiens Sp7 transcription factor (SP7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SP7 ( NM_152860.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_690599.1 Homo sapiens Sp7 transcription factor (SP7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu19040
Clone ID Related Accession (Same CDS sequence)	NM_152860.2 , NM_001173467.2 , NM_001173467.3 , NM_152860.1
Accession Version	NM_152860.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	transcription factor Sp7 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073611.29 and AF477981.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_152860.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF477981.1, AF466179.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCT CCCTGCTTGA GGAGGAAGTT CACTATGGCT CCAGTCCCCT GGCCATGCTG 
ACGGCAGCGT GCAGCAAATT TGGTGGCTCT AGCCCTCTGC GGGACTCAAC AACTCTGGGC 
AAAGCAGGCA CAAAGAAGCC GTACTCTGTG GGCAGTGACC TTTCAGCCTC CAAAACCATG 
GGGGATGCTT ATCCAGCCCC CTTTACAAGC ACTAATGGGC TCCTTTCACC TGCAGGCAGT 
CCTCCAGCAC CCACCTCAGG CTATGCTAAT GATTACCCTC CCTTTTCCCA CTCATTCCCT 
GGGCCCACAG GCACCCAGGA CCCTGGGCTA CTAGTGCCCA AGGGGCACAG CTCTTCTGAC 
TGTCTGCCCA GTGTCTACAC CTCTCTGGAC ATGACACACC CCTATGGCTC CTGGTACAAG 
GCAGGCATCC ATGCAGGCAT TTCACCAGGC CCAGGCAACA CTCCTACTCC ATGGTGGGAT 
ATGCACCCTG GAGGCAACTG GCTAGGTGGT GGGCAGGGCC AGGGTGATGG GCTGCAAGGG 
ACACTGCCCA CAGGTCCAGC TCAGCCTCCA CTGAACCCCC AGCTGCCCAC CTACCCATCT 
GACTTTGCTC CCCTTAATCC AGCCCCCTAC CCAGCTCCCC ACCTCTTGCA ACCAGGGCCC 
CAGCATGTCT TGCCCCAAGA TGTCTATAAA CCCAAGGCAG TGGGAAATAG TGGGCAGCTA 
GAAGGGAGTG GTGGAGCCAA ACCCCCACGG GGTGCAAGCA CTGGGGGTAG TGGTGGATAT 
GGGGGCAGTG GGGCAGGGCG CTCCTCCTGC GACTGCCCTA ATTGCCAGGA GCTAGAGCGG 
CTGGGAGCAG CAGCGGCTGG GCTGCGGAAG AAGCCCATCC ACAGCTGCCA CATCCCTGGC 
TGCGGCAAGG TGTATGGCAA GGCTTCGCAC CTGAAGGCCC ACTTGCGCTG GCACACAGGC 
GAGAGGCCCT TCGTCTGCAA CTGGCTCTTC TGCGGCAAGA GGTTCACTCG TTCGGATGAG 
CTGGAGCGTC ATGTGCGCAC TCACACCCGG GAGAAGAAGT TCACCTGCCT GCTCTGCTCC 
AAGCGCTTTA CCCGAAGCGA CCACCTGAGC AAACACCAGC GCACCCATGG AGAACCAGGC 
CCGGGTCCCC CTCCCAGTGG CCCCAAGGAG CTGGGGGAGG GCCGCAGCAC GGGGGAAGAG 
GAGGCCAGTC AGACGCCCCG ACCTTCTGCC TCGCCAGCAA CCCCAGAGAA AGCCCCTGGA 
GGCAGCCCTG AGCAGAGCAA CTTGCTGGAG ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690599.1
CDS	131..1426
Translation	MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQLEGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSPEQSNLLEI

Target ORF information:

RefSeq Version	NM_152860.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp7 transcription factor (SP7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152860.2

ORF Insert Sequence:

ATGGCGTCCT CCCTGCTTGA GGAGGAAGTT CACTATGGCT CCAGTCCCCT GGCCATGCTG 
ACGGCAGCGT GCAGCAAATT TGGTGGCTCT AGCCCTCTGC GGGACTCAAC AACTCTGGGC 
AAAGCAGGCA CAAAGAAGCC GTACTCTGTG GGCAGTGACC TTTCAGCCTC CAAAACCATG 
GGGGATGCTT ATCCAGCCCC CTTTACAAGC ACTAATGGGC TCCTTTCACC TGCAGGCAGT 
CCTCCAGCAC CCACCTCAGG CTATGCTAAT GATTACCCTC CCTTTTCCCA CTCATTCCCT 
GGGCCCACAG GCACCCAGGA CCCTGGGCTA CTAGTGCCCA AGGGGCACAG CTCTTCTGAC 
TGTCTGCCCA GTGTCTACAC CTCTCTGGAC ATGACACACC CCTATGGCTC CTGGTACAAG 
GCAGGCATCC ATGCAGGCAT TTCACCAGGC CCAGGCAACA CTCCTACTCC ATGGTGGGAT 
ATGCACCCTG GAGGCAACTG GCTAGGTGGT GGGCAGGGCC AGGGTGATGG GCTGCAAGGG 
ACACTGCCCA CAGGTCCAGC TCAGCCTCCA CTGAACCCCC AGCTGCCCAC CTACCCATCT 
GACTTTGCTC CCCTTAATCC AGCCCCCTAC CCAGCTCCCC ACCTCTTGCA ACCAGGGCCC 
CAGCATGTCT TGCCCCAAGA TGTCTATAAA CCCAAGGCAG TGGGAAATAG TGGGCAGCTA 
GAAGGGAGTG GTGGAGCCAA ACCCCCACGG GGTGCAAGCA CTGGGGGTAG TGGTGGATAT 
GGGGGCAGTG GGGCAGGGCG CTCCTCCTGC GACTGCCCTA ATTGCCAGGA GCTAGAGCGG 
CTGGGAGCAG CAGCGGCTGG GCTGCGGAAG AAGCCCATCC ACAGCTGCCA CATCCCTGGC 
TGCGGCAAGG TGTATGGCAA GGCTTCGCAC CTGAAGGCCC ACTTGCGCTG GCACACAGGC 
GAGAGGCCCT TCGTCTGCAA CTGGCTCTTC TGCGGCAAGA GGTTCACTCG TTCGGATGAG 
CTGGAGCGTC ATGTGCGCAC TCACACCCGG GAGAAGAAGT TCACCTGCCT GCTCTGCTCC 
AAGCGCTTTA CCCGAAGCGA CCACCTGAGC AAACACCAGC GCACCCATGG AGAACCAGGC 
CCGGGTCCCC CTCCCAGTGG CCCCAAGGAG CTGGGGGAGG GCCGCAGCAC GGGGGAAGAG 
GAGGCCAGTC AGACGCCCCG ACCTTCTGCC TCGCCAGCAA CCCCAGAGAA AGCCCCTGGA 
GGCAGCCCTG AGCAGAGCAA CTTGCTGGAG ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SP7 ( NM_001173467.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001166938.1 Homo sapiens Sp7 transcription factor (SP7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19040
Clone ID Related Accession (Same CDS sequence)	NM_152860.2 , NM_001173467.2 , NM_001173467.3 , NM_152860.1
Accession Version	NM_001173467.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-11
Organism	Homo sapiens(human)
Product	transcription factor Sp7 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073611.29, AK128520.1 and AF477981.1. On Jul 15, 2014 this sequence version replaced NM_001173467.1. Transcript Variant: This variant (1) encodes the longer isoform (a). Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK128520.1, CN287220.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145240, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCT CCCTGCTTGA GGAGGAAGTT CACTATGGCT CCAGTCCCCT GGCCATGCTG 
ACGGCAGCGT GCAGCAAATT TGGTGGCTCT AGCCCTCTGC GGGACTCAAC AACTCTGGGC 
AAAGCAGGCA CAAAGAAGCC GTACTCTGTG GGCAGTGACC TTTCAGCCTC CAAAACCATG 
GGGGATGCTT ATCCAGCCCC CTTTACAAGC ACTAATGGGC TCCTTTCACC TGCAGGCAGT 
CCTCCAGCAC CCACCTCAGG CTATGCTAAT GATTACCCTC CCTTTTCCCA CTCATTCCCT 
GGGCCCACAG GCACCCAGGA CCCTGGGCTA CTAGTGCCCA AGGGGCACAG CTCTTCTGAC 
TGTCTGCCCA GTGTCTACAC CTCTCTGGAC ATGACACACC CCTATGGCTC CTGGTACAAG 
GCAGGCATCC ATGCAGGCAT TTCACCAGGC CCAGGCAACA CTCCTACTCC ATGGTGGGAT 
ATGCACCCTG GAGGCAACTG GCTAGGTGGT GGGCAGGGCC AGGGTGATGG GCTGCAAGGG 
ACACTGCCCA CAGGTCCAGC TCAGCCTCCA CTGAACCCCC AGCTGCCCAC CTACCCATCT 
GACTTTGCTC CCCTTAATCC AGCCCCCTAC CCAGCTCCCC ACCTCTTGCA ACCAGGGCCC 
CAGCATGTCT TGCCCCAAGA TGTCTATAAA CCCAAGGCAG TGGGAAATAG TGGGCAGCTA 
GAAGGGAGTG GTGGAGCCAA ACCCCCACGG GGTGCAAGCA CTGGGGGTAG TGGTGGATAT 
GGGGGCAGTG GGGCAGGGCG CTCCTCCTGC GACTGCCCTA ATTGCCAGGA GCTAGAGCGG 
CTGGGAGCAG CAGCGGCTGG GCTGCGGAAG AAGCCCATCC ACAGCTGCCA CATCCCTGGC 
TGCGGCAAGG TGTATGGCAA GGCTTCGCAC CTGAAGGCCC ACTTGCGCTG GCACACAGGC 
GAGAGGCCCT TCGTCTGCAA CTGGCTCTTC TGCGGCAAGA GGTTCACTCG TTCGGATGAG 
CTGGAGCGTC ATGTGCGCAC TCACACCCGG GAGAAGAAGT TCACCTGCCT GCTCTGCTCC 
AAGCGCTTTA CCCGAAGCGA CCACCTGAGC AAACACCAGC GCACCCATGG AGAACCAGGC 
CCGGGTCCCC CTCCCAGTGG CCCCAAGGAG CTGGGGGAGG GCCGCAGCAC GGGGGAAGAG 
GAGGCCAGTC AGACGCCCCG ACCTTCTGCC TCGCCAGCAA CCCCAGAGAA AGCCCCTGGA 
GGCAGCCCTG AGCAGAGCAA CTTGCTGGAG ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166938.1
CDS	286..1581
Translation	MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQLEGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSPEQSNLLEI

Target ORF information:

RefSeq Version	NM_001173467.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp7 transcription factor (SP7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001173467.2

ORF Insert Sequence:

ATGGCGTCCT CCCTGCTTGA GGAGGAAGTT CACTATGGCT CCAGTCCCCT GGCCATGCTG 
ACGGCAGCGT GCAGCAAATT TGGTGGCTCT AGCCCTCTGC GGGACTCAAC AACTCTGGGC 
AAAGCAGGCA CAAAGAAGCC GTACTCTGTG GGCAGTGACC TTTCAGCCTC CAAAACCATG 
GGGGATGCTT ATCCAGCCCC CTTTACAAGC ACTAATGGGC TCCTTTCACC TGCAGGCAGT 
CCTCCAGCAC CCACCTCAGG CTATGCTAAT GATTACCCTC CCTTTTCCCA CTCATTCCCT 
GGGCCCACAG GCACCCAGGA CCCTGGGCTA CTAGTGCCCA AGGGGCACAG CTCTTCTGAC 
TGTCTGCCCA GTGTCTACAC CTCTCTGGAC ATGACACACC CCTATGGCTC CTGGTACAAG 
GCAGGCATCC ATGCAGGCAT TTCACCAGGC CCAGGCAACA CTCCTACTCC ATGGTGGGAT 
ATGCACCCTG GAGGCAACTG GCTAGGTGGT GGGCAGGGCC AGGGTGATGG GCTGCAAGGG 
ACACTGCCCA CAGGTCCAGC TCAGCCTCCA CTGAACCCCC AGCTGCCCAC CTACCCATCT 
GACTTTGCTC CCCTTAATCC AGCCCCCTAC CCAGCTCCCC ACCTCTTGCA ACCAGGGCCC 
CAGCATGTCT TGCCCCAAGA TGTCTATAAA CCCAAGGCAG TGGGAAATAG TGGGCAGCTA 
GAAGGGAGTG GTGGAGCCAA ACCCCCACGG GGTGCAAGCA CTGGGGGTAG TGGTGGATAT 
GGGGGCAGTG GGGCAGGGCG CTCCTCCTGC GACTGCCCTA ATTGCCAGGA GCTAGAGCGG 
CTGGGAGCAG CAGCGGCTGG GCTGCGGAAG AAGCCCATCC ACAGCTGCCA CATCCCTGGC 
TGCGGCAAGG TGTATGGCAA GGCTTCGCAC CTGAAGGCCC ACTTGCGCTG GCACACAGGC 
GAGAGGCCCT TCGTCTGCAA CTGGCTCTTC TGCGGCAAGA GGTTCACTCG TTCGGATGAG 
CTGGAGCGTC ATGTGCGCAC TCACACCCGG GAGAAGAAGT TCACCTGCCT GCTCTGCTCC 
AAGCGCTTTA CCCGAAGCGA CCACCTGAGC AAACACCAGC GCACCCATGG AGAACCAGGC 
CCGGGTCCCC CTCCCAGTGG CCCCAAGGAG CTGGGGGAGG GCCGCAGCAC GGGGGAAGAG 
GAGGCCAGTC AGACGCCCCG ACCTTCTGCC TCGCCAGCAA CCCCAGAGAA AGCCCCTGGA 
GGCAGCCCTG AGCAGAGCAA CTTGCTGGAG ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SP7 ( NM_001173467.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001166938.1 Homo sapiens Sp7 transcription factor (SP7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19040
Clone ID Related Accession (Same CDS sequence)	NM_152860.2 , NM_001173467.2 , NM_001173467.3 , NM_152860.1
Accession Version	NM_001173467.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	transcription factor Sp7 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK128520.1 and AF477981.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_001173467.2. Transcript Variant: This variant (1) encodes the longer isoform (a). Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK128520.1, CN287220.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145240, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000536324.4/ ENSP00000443827.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGTCCT CCCTGCTTGA GGAGGAAGTT CACTATGGCT CCAGTCCCCT GGCCATGCTG 
ACGGCAGCGT GCAGCAAATT TGGTGGCTCT AGCCCTCTGC GGGACTCAAC AACTCTGGGC 
AAAGCAGGCA CAAAGAAGCC GTACTCTGTG GGCAGTGACC TTTCAGCCTC CAAAACCATG 
GGGGATGCTT ATCCAGCCCC CTTTACAAGC ACTAATGGGC TCCTTTCACC TGCAGGCAGT 
CCTCCAGCAC CCACCTCAGG CTATGCTAAT GATTACCCTC CCTTTTCCCA CTCATTCCCT 
GGGCCCACAG GCACCCAGGA CCCTGGGCTA CTAGTGCCCA AGGGGCACAG CTCTTCTGAC 
TGTCTGCCCA GTGTCTACAC CTCTCTGGAC ATGACACACC CCTATGGCTC CTGGTACAAG 
GCAGGCATCC ATGCAGGCAT TTCACCAGGC CCAGGCAACA CTCCTACTCC ATGGTGGGAT 
ATGCACCCTG GAGGCAACTG GCTAGGTGGT GGGCAGGGCC AGGGTGATGG GCTGCAAGGG 
ACACTGCCCA CAGGTCCAGC TCAGCCTCCA CTGAACCCCC AGCTGCCCAC CTACCCATCT 
GACTTTGCTC CCCTTAATCC AGCCCCCTAC CCAGCTCCCC ACCTCTTGCA ACCAGGGCCC 
CAGCATGTCT TGCCCCAAGA TGTCTATAAA CCCAAGGCAG TGGGAAATAG TGGGCAGCTA 
GAAGGGAGTG GTGGAGCCAA ACCCCCACGG GGTGCAAGCA CTGGGGGTAG TGGTGGATAT 
GGGGGCAGTG GGGCAGGGCG CTCCTCCTGC GACTGCCCTA ATTGCCAGGA GCTAGAGCGG 
CTGGGAGCAG CAGCGGCTGG GCTGCGGAAG AAGCCCATCC ACAGCTGCCA CATCCCTGGC 
TGCGGCAAGG TGTATGGCAA GGCTTCGCAC CTGAAGGCCC ACTTGCGCTG GCACACAGGC 
GAGAGGCCCT TCGTCTGCAA CTGGCTCTTC TGCGGCAAGA GGTTCACTCG TTCGGATGAG 
CTGGAGCGTC ATGTGCGCAC TCACACCCGG GAGAAGAAGT TCACCTGCCT GCTCTGCTCC 
AAGCGCTTTA CCCGAAGCGA CCACCTGAGC AAACACCAGC GCACCCATGG AGAACCAGGC 
CCGGGTCCCC CTCCCAGTGG CCCCAAGGAG CTGGGGGAGG GCCGCAGCAC GGGGGAAGAG 
GAGGCCAGTC AGACGCCCCG ACCTTCTGCC TCGCCAGCAA CCCCAGAGAA AGCCCCTGGA 
GGCAGCCCTG AGCAGAGCAA CTTGCTGGAG ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166938.1
CDS	257..1552
Translation	MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQLEGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSPEQSNLLEI

Target ORF information:

RefSeq Version	NM_001173467.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp7 transcription factor (SP7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001173467.3

ORF Insert Sequence:

ATGGCGTCCT CCCTGCTTGA GGAGGAAGTT CACTATGGCT CCAGTCCCCT GGCCATGCTG 
ACGGCAGCGT GCAGCAAATT TGGTGGCTCT AGCCCTCTGC GGGACTCAAC AACTCTGGGC 
AAAGCAGGCA CAAAGAAGCC GTACTCTGTG GGCAGTGACC TTTCAGCCTC CAAAACCATG 
GGGGATGCTT ATCCAGCCCC CTTTACAAGC ACTAATGGGC TCCTTTCACC TGCAGGCAGT 
CCTCCAGCAC CCACCTCAGG CTATGCTAAT GATTACCCTC CCTTTTCCCA CTCATTCCCT 
GGGCCCACAG GCACCCAGGA CCCTGGGCTA CTAGTGCCCA AGGGGCACAG CTCTTCTGAC 
TGTCTGCCCA GTGTCTACAC CTCTCTGGAC ATGACACACC CCTATGGCTC CTGGTACAAG 
GCAGGCATCC ATGCAGGCAT TTCACCAGGC CCAGGCAACA CTCCTACTCC ATGGTGGGAT 
ATGCACCCTG GAGGCAACTG GCTAGGTGGT GGGCAGGGCC AGGGTGATGG GCTGCAAGGG 
ACACTGCCCA CAGGTCCAGC TCAGCCTCCA CTGAACCCCC AGCTGCCCAC CTACCCATCT 
GACTTTGCTC CCCTTAATCC AGCCCCCTAC CCAGCTCCCC ACCTCTTGCA ACCAGGGCCC 
CAGCATGTCT TGCCCCAAGA TGTCTATAAA CCCAAGGCAG TGGGAAATAG TGGGCAGCTA 
GAAGGGAGTG GTGGAGCCAA ACCCCCACGG GGTGCAAGCA CTGGGGGTAG TGGTGGATAT 
GGGGGCAGTG GGGCAGGGCG CTCCTCCTGC GACTGCCCTA ATTGCCAGGA GCTAGAGCGG 
CTGGGAGCAG CAGCGGCTGG GCTGCGGAAG AAGCCCATCC ACAGCTGCCA CATCCCTGGC 
TGCGGCAAGG TGTATGGCAA GGCTTCGCAC CTGAAGGCCC ACTTGCGCTG GCACACAGGC 
GAGAGGCCCT TCGTCTGCAA CTGGCTCTTC TGCGGCAAGA GGTTCACTCG TTCGGATGAG 
CTGGAGCGTC ATGTGCGCAC TCACACCCGG GAGAAGAAGT TCACCTGCCT GCTCTGCTCC 
AAGCGCTTTA CCCGAAGCGA CCACCTGAGC AAACACCAGC GCACCCATGG AGAACCAGGC 
CCGGGTCCCC CTCCCAGTGG CCCCAAGGAG CTGGGGGAGG GCCGCAGCAC GGGGGAAGAG 
GAGGCCAGTC AGACGCCCCG ACCTTCTGCC TCGCCAGCAA CCCCAGAGAA AGCCCCTGGA 
GGCAGCCCTG AGCAGAGCAA CTTGCTGGAG ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SP7 ( NM_152860.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_690599.1 Homo sapiens Sp7 transcription factor (SP7), transcript variant 2, mRNA.

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CloneID	OHu19040
Clone ID Related Accession (Same CDS sequence)	NM_152860.2 , NM_001173467.2 , NM_001173467.3 , NM_152860.1
Accession Version	NM_152860.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	transcription factor Sp7 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF477981.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF477981.1, AF466179.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144120, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCT CCCTGCTTGA GGAGGAAGTT CACTATGGCT CCAGTCCCCT GGCCATGCTG 
ACGGCAGCGT GCAGCAAATT TGGTGGCTCT AGCCCTCTGC GGGACTCAAC AACTCTGGGC 
AAAGCAGGCA CAAAGAAGCC GTACTCTGTG GGCAGTGACC TTTCAGCCTC CAAAACCATG 
GGGGATGCTT ATCCAGCCCC CTTTACAAGC ACTAATGGGC TCCTTTCACC TGCAGGCAGT 
CCTCCAGCAC CCACCTCAGG CTATGCTAAT GATTACCCTC CCTTTTCCCA CTCATTCCCT 
GGGCCCACAG GCACCCAGGA CCCTGGGCTA CTAGTGCCCA AGGGGCACAG CTCTTCTGAC 
TGTCTGCCCA GTGTCTACAC CTCTCTGGAC ATGACACACC CCTATGGCTC CTGGTACAAG 
GCAGGCATCC ATGCAGGCAT TTCACCAGGC CCAGGCAACA CTCCTACTCC ATGGTGGGAT 
ATGCACCCTG GAGGCAACTG GCTAGGTGGT GGGCAGGGCC AGGGTGATGG GCTGCAAGGG 
ACACTGCCCA CAGGTCCAGC TCAGCCTCCA CTGAACCCCC AGCTGCCCAC CTACCCATCT 
GACTTTGCTC CCCTTAATCC AGCCCCCTAC CCAGCTCCCC ACCTCTTGCA ACCAGGGCCC 
CAGCATGTCT TGCCCCAAGA TGTCTATAAA CCCAAGGCAG TGGGAAATAG TGGGCAGCTA 
GAAGGGAGTG GTGGAGCCAA ACCCCCACGG GGTGCAAGCA CTGGGGGTAG TGGTGGATAT 
GGGGGCAGTG GGGCAGGGCG CTCCTCCTGC GACTGCCCTA ATTGCCAGGA GCTAGAGCGG 
CTGGGAGCAG CAGCGGCTGG GCTGCGGAAG AAGCCCATCC ACAGCTGCCA CATCCCTGGC 
TGCGGCAAGG TGTATGGCAA GGCTTCGCAC CTGAAGGCCC ACTTGCGCTG GCACACAGGC 
GAGAGGCCCT TCGTCTGCAA CTGGCTCTTC TGCGGCAAGA GGTTCACTCG TTCGGATGAG 
CTGGAGCGTC ATGTGCGCAC TCACACCCGG GAGAAGAAGT TCACCTGCCT GCTCTGCTCC 
AAGCGCTTTA CCCGAAGCGA CCACCTGAGC AAACACCAGC GCACCCATGG AGAACCAGGC 
CCGGGTCCCC CTCCCAGTGG CCCCAAGGAG CTGGGGGAGG GCCGCAGCAC GGGGGAAGAG 
GAGGCCAGTC AGACGCCCCG ACCTTCTGCC TCGCCAGCAA CCCCAGAGAA AGCCCCTGGA 
GGCAGCCCTG AGCAGAGCAA CTTGCTGGAG ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690599.1
CDS	108..1403
Translation	MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQLEGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSPEQSNLLEI

Target ORF information:

RefSeq Version	NM_152860.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp7 transcription factor (SP7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152860.1

ORF Insert Sequence:

ATGGCGTCCT CCCTGCTTGA GGAGGAAGTT CACTATGGCT CCAGTCCCCT GGCCATGCTG 
ACGGCAGCGT GCAGCAAATT TGGTGGCTCT AGCCCTCTGC GGGACTCAAC AACTCTGGGC 
AAAGCAGGCA CAAAGAAGCC GTACTCTGTG GGCAGTGACC TTTCAGCCTC CAAAACCATG 
GGGGATGCTT ATCCAGCCCC CTTTACAAGC ACTAATGGGC TCCTTTCACC TGCAGGCAGT 
CCTCCAGCAC CCACCTCAGG CTATGCTAAT GATTACCCTC CCTTTTCCCA CTCATTCCCT 
GGGCCCACAG GCACCCAGGA CCCTGGGCTA CTAGTGCCCA AGGGGCACAG CTCTTCTGAC 
TGTCTGCCCA GTGTCTACAC CTCTCTGGAC ATGACACACC CCTATGGCTC CTGGTACAAG 
GCAGGCATCC ATGCAGGCAT TTCACCAGGC CCAGGCAACA CTCCTACTCC ATGGTGGGAT 
ATGCACCCTG GAGGCAACTG GCTAGGTGGT GGGCAGGGCC AGGGTGATGG GCTGCAAGGG 
ACACTGCCCA CAGGTCCAGC TCAGCCTCCA CTGAACCCCC AGCTGCCCAC CTACCCATCT 
GACTTTGCTC CCCTTAATCC AGCCCCCTAC CCAGCTCCCC ACCTCTTGCA ACCAGGGCCC 
CAGCATGTCT TGCCCCAAGA TGTCTATAAA CCCAAGGCAG TGGGAAATAG TGGGCAGCTA 
GAAGGGAGTG GTGGAGCCAA ACCCCCACGG GGTGCAAGCA CTGGGGGTAG TGGTGGATAT 
GGGGGCAGTG GGGCAGGGCG CTCCTCCTGC GACTGCCCTA ATTGCCAGGA GCTAGAGCGG 
CTGGGAGCAG CAGCGGCTGG GCTGCGGAAG AAGCCCATCC ACAGCTGCCA CATCCCTGGC 
TGCGGCAAGG TGTATGGCAA GGCTTCGCAC CTGAAGGCCC ACTTGCGCTG GCACACAGGC 
GAGAGGCCCT TCGTCTGCAA CTGGCTCTTC TGCGGCAAGA GGTTCACTCG TTCGGATGAG 
CTGGAGCGTC ATGTGCGCAC TCACACCCGG GAGAAGAAGT TCACCTGCCT GCTCTGCTCC 
AAGCGCTTTA CCCGAAGCGA CCACCTGAGC AAACACCAGC GCACCCATGG AGAACCAGGC 
CCGGGTCCCC CTCCCAGTGG CCCCAAGGAG CTGGGGGAGG GCCGCAGCAC GGGGGAAGAG 
GAGGCCAGTC AGACGCCCCG ACCTTCTGCC TCGCCAGCAA CCCCAGAGAA AGCCCCTGGA 
GGCAGCCCTG AGCAGAGCAA CTTGCTGGAG ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SP7 ( NM_001300837.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001287766.1 Homo sapiens Sp7 transcription factor (SP7), transcript variant 3, mRNA.

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CloneID	OHu46319
Clone ID Related Accession (Same CDS sequence)	NM_001300837.1 , XM_011537900.2
Accession Version	NM_001300837.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	transcription factor Sp7 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY020346.1, AC073611.29, AY150674.1 and AF477981.1. On Jul 15, 2014 this sequence version replaced XM_005268643.2. Transcript Variant: This variant (3) differs in the 5' structure, resulting in the use of a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HY020346.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2151119 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGACGG CAGCGTGCAG CAAATTTGGT GGCTCTAGCC CTCTGCGGGA CTCAACAACT 
CTGGGCAAAG CAGGCACAAA GAAGCCGTAC TCTGTGGGCA GTGACCTTTC AGCCTCCAAA 
ACCATGGGGG ATGCTTATCC AGCCCCCTTT ACAAGCACTA ATGGGCTCCT TTCACCTGCA 
GGCAGTCCTC CAGCACCCAC CTCAGGCTAT GCTAATGATT ACCCTCCCTT TTCCCACTCA 
TTCCCTGGGC CCACAGGCAC CCAGGACCCT GGGCTACTAG TGCCCAAGGG GCACAGCTCT 
TCTGACTGTC TGCCCAGTGT CTACACCTCT CTGGACATGA CACACCCCTA TGGCTCCTGG 
TACAAGGCAG GCATCCATGC AGGCATTTCA CCAGGCCCAG GCAACACTCC TACTCCATGG 
TGGGATATGC ACCCTGGAGG CAACTGGCTA GGTGGTGGGC AGGGCCAGGG TGATGGGCTG 
CAAGGGACAC TGCCCACAGG TCCAGCTCAG CCTCCACTGA ACCCCCAGCT GCCCACCTAC 
CCATCTGACT TTGCTCCCCT TAATCCAGCC CCCTACCCAG CTCCCCACCT CTTGCAACCA 
GGGCCCCAGC ATGTCTTGCC CCAAGATGTC TATAAACCCA AGGCAGTGGG AAATAGTGGG 
CAGCTAGAAG GGAGTGGTGG AGCCAAACCC CCACGGGGTG CAAGCACTGG GGGTAGTGGT 
GGATATGGGG GCAGTGGGGC AGGGCGCTCC TCCTGCGACT GCCCTAATTG CCAGGAGCTA 
GAGCGGCTGG GAGCAGCAGC GGCTGGGCTG CGGAAGAAGC CCATCCACAG CTGCCACATC 
CCTGGCTGCG GCAAGGTGTA TGGCAAGGCT TCGCACCTGA AGGCCCACTT GCGCTGGCAC 
ACAGGCGAGA GGCCCTTCGT CTGCAACTGG CTCTTCTGCG GCAAGAGGTT CACTCGTTCG 
GATGAGCTGG AGCGTCATGT GCGCACTCAC ACCCGGGAGA AGAAGTTCAC CTGCCTGCTC 
TGCTCCAAGC GCTTTACCCG AAGCGACCAC CTGAGCAAAC ACCAGCGCAC CCATGGAGAA 
CCAGGCCCGG GTCCCCCTCC CAGTGGCCCC AAGGAGCTGG GGGAGGGCCG CAGCACGGGG 
GAAGAGGAGG CCAGTCAGAC GCCCCGACCT TCTGCCTCGC CAGCAACCCC AGAGAAAGCC 
CCTGGAGGCA GCCCTGAGCA GAGCAACTTG CTGGAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287766.1
CDS	378..1619
Translation	MLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQLEGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSPEQSNLLEI

Target ORF information:

RefSeq Version	NM_001300837.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp7 transcription factor (SP7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300837.1

ORF Insert Sequence:

ATGCTGACGG CAGCGTGCAG CAAATTTGGT GGCTCTAGCC CTCTGCGGGA CTCAACAACT 
CTGGGCAAAG CAGGCACAAA GAAGCCGTAC TCTGTGGGCA GTGACCTTTC AGCCTCCAAA 
ACCATGGGGG ATGCTTATCC AGCCCCCTTT ACAAGCACTA ATGGGCTCCT TTCACCTGCA 
GGCAGTCCTC CAGCACCCAC CTCAGGCTAT GCTAATGATT ACCCTCCCTT TTCCCACTCA 
TTCCCTGGGC CCACAGGCAC CCAGGACCCT GGGCTACTAG TGCCCAAGGG GCACAGCTCT 
TCTGACTGTC TGCCCAGTGT CTACACCTCT CTGGACATGA CACACCCCTA TGGCTCCTGG 
TACAAGGCAG GCATCCATGC AGGCATTTCA CCAGGCCCAG GCAACACTCC TACTCCATGG 
TGGGATATGC ACCCTGGAGG CAACTGGCTA GGTGGTGGGC AGGGCCAGGG TGATGGGCTG 
CAAGGGACAC TGCCCACAGG TCCAGCTCAG CCTCCACTGA ACCCCCAGCT GCCCACCTAC 
CCATCTGACT TTGCTCCCCT TAATCCAGCC CCCTACCCAG CTCCCCACCT CTTGCAACCA 
GGGCCCCAGC ATGTCTTGCC CCAAGATGTC TATAAACCCA AGGCAGTGGG AAATAGTGGG 
CAGCTAGAAG GGAGTGGTGG AGCCAAACCC CCACGGGGTG CAAGCACTGG GGGTAGTGGT 
GGATATGGGG GCAGTGGGGC AGGGCGCTCC TCCTGCGACT GCCCTAATTG CCAGGAGCTA 
GAGCGGCTGG GAGCAGCAGC GGCTGGGCTG CGGAAGAAGC CCATCCACAG CTGCCACATC 
CCTGGCTGCG GCAAGGTGTA TGGCAAGGCT TCGCACCTGA AGGCCCACTT GCGCTGGCAC 
ACAGGCGAGA GGCCCTTCGT CTGCAACTGG CTCTTCTGCG GCAAGAGGTT CACTCGTTCG 
GATGAGCTGG AGCGTCATGT GCGCACTCAC ACCCGGGAGA AGAAGTTCAC CTGCCTGCTC 
TGCTCCAAGC GCTTTACCCG AAGCGACCAC CTGAGCAAAC ACCAGCGCAC CCATGGAGAA 
CCAGGCCCGG GTCCCCCTCC CAGTGGCCCC AAGGAGCTGG GGGAGGGCCG CAGCACGGGG 
GAAGAGGAGG CCAGTCAGAC GCCCCGACCT TCTGCCTCGC CAGCAACCCC AGAGAAAGCC 
CCTGGAGGCA GCCCTGAGCA GAGCAACTTG CTGGAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SP7 ( XM_011537900.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011536202.1 Homo sapiens Sp7 transcription factor (SP7), transcript variant X1, mRNA.

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CloneID	OHu46319
Clone ID Related Accession (Same CDS sequence)	NM_001300837.1 , XM_011537900.2
Accession Version	XM_011537900.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transcription factor Sp7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011537900.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGACGG CAGCGTGCAG CAAATTTGGT GGCTCTAGCC CTCTGCGGGA CTCAACAACT 
CTGGGCAAAG CAGGCACAAA GAAGCCGTAC TCTGTGGGCA GTGACCTTTC AGCCTCCAAA 
ACCATGGGGG ATGCTTATCC AGCCCCCTTT ACAAGCACTA ATGGGCTCCT TTCACCTGCA 
GGCAGTCCTC CAGCACCCAC CTCAGGCTAT GCTAATGATT ACCCTCCCTT TTCCCACTCA 
TTCCCTGGGC CCACAGGCAC CCAGGACCCT GGGCTACTAG TGCCCAAGGG GCACAGCTCT 
TCTGACTGTC TGCCCAGTGT CTACACCTCT CTGGACATGA CACACCCCTA TGGCTCCTGG 
TACAAGGCAG GCATCCATGC AGGCATTTCA CCAGGCCCAG GCAACACTCC TACTCCATGG 
TGGGATATGC ACCCTGGAGG CAACTGGCTA GGTGGTGGGC AGGGCCAGGG TGATGGGCTG 
CAAGGGACAC TGCCCACAGG TCCAGCTCAG CCTCCACTGA ACCCCCAGCT GCCCACCTAC 
CCATCTGACT TTGCTCCCCT TAATCCAGCC CCCTACCCAG CTCCCCACCT CTTGCAACCA 
GGGCCCCAGC ATGTCTTGCC CCAAGATGTC TATAAACCCA AGGCAGTGGG AAATAGTGGG 
CAGCTAGAAG GGAGTGGTGG AGCCAAACCC CCACGGGGTG CAAGCACTGG GGGTAGTGGT 
GGATATGGGG GCAGTGGGGC AGGGCGCTCC TCCTGCGACT GCCCTAATTG CCAGGAGCTA 
GAGCGGCTGG GAGCAGCAGC GGCTGGGCTG CGGAAGAAGC CCATCCACAG CTGCCACATC 
CCTGGCTGCG GCAAGGTGTA TGGCAAGGCT TCGCACCTGA AGGCCCACTT GCGCTGGCAC 
ACAGGCGAGA GGCCCTTCGT CTGCAACTGG CTCTTCTGCG GCAAGAGGTT CACTCGTTCG 
GATGAGCTGG AGCGTCATGT GCGCACTCAC ACCCGGGAGA AGAAGTTCAC CTGCCTGCTC 
TGCTCCAAGC GCTTTACCCG AAGCGACCAC CTGAGCAAAC ACCAGCGCAC CCATGGAGAA 
CCAGGCCCGG GTCCCCCTCC CAGTGGCCCC AAGGAGCTGG GGGAGGGCCG CAGCACGGGG 
GAAGAGGAGG CCAGTCAGAC GCCCCGACCT TCTGCCTCGC CAGCAACCCC AGAGAAAGCC 
CCTGGAGGCA GCCCTGAGCA GAGCAACTTG CTGGAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011536202.1
CDS	429..1670
Translation	MLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQLEGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSPEQSNLLEI

Target ORF information:

RefSeq Version	XM_011537900.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp7 transcription factor (SP7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537900.2

ORF Insert Sequence:

ATGCTGACGG CAGCGTGCAG CAAATTTGGT GGCTCTAGCC CTCTGCGGGA CTCAACAACT 
CTGGGCAAAG CAGGCACAAA GAAGCCGTAC TCTGTGGGCA GTGACCTTTC AGCCTCCAAA 
ACCATGGGGG ATGCTTATCC AGCCCCCTTT ACAAGCACTA ATGGGCTCCT TTCACCTGCA 
GGCAGTCCTC CAGCACCCAC CTCAGGCTAT GCTAATGATT ACCCTCCCTT TTCCCACTCA 
TTCCCTGGGC CCACAGGCAC CCAGGACCCT GGGCTACTAG TGCCCAAGGG GCACAGCTCT 
TCTGACTGTC TGCCCAGTGT CTACACCTCT CTGGACATGA CACACCCCTA TGGCTCCTGG 
TACAAGGCAG GCATCCATGC AGGCATTTCA CCAGGCCCAG GCAACACTCC TACTCCATGG 
TGGGATATGC ACCCTGGAGG CAACTGGCTA GGTGGTGGGC AGGGCCAGGG TGATGGGCTG 
CAAGGGACAC TGCCCACAGG TCCAGCTCAG CCTCCACTGA ACCCCCAGCT GCCCACCTAC 
CCATCTGACT TTGCTCCCCT TAATCCAGCC CCCTACCCAG CTCCCCACCT CTTGCAACCA 
GGGCCCCAGC ATGTCTTGCC CCAAGATGTC TATAAACCCA AGGCAGTGGG AAATAGTGGG 
CAGCTAGAAG GGAGTGGTGG AGCCAAACCC CCACGGGGTG CAAGCACTGG GGGTAGTGGT 
GGATATGGGG GCAGTGGGGC AGGGCGCTCC TCCTGCGACT GCCCTAATTG CCAGGAGCTA 
GAGCGGCTGG GAGCAGCAGC GGCTGGGCTG CGGAAGAAGC CCATCCACAG CTGCCACATC 
CCTGGCTGCG GCAAGGTGTA TGGCAAGGCT TCGCACCTGA AGGCCCACTT GCGCTGGCAC 
ACAGGCGAGA GGCCCTTCGT CTGCAACTGG CTCTTCTGCG GCAAGAGGTT CACTCGTTCG 
GATGAGCTGG AGCGTCATGT GCGCACTCAC ACCCGGGAGA AGAAGTTCAC CTGCCTGCTC 
TGCTCCAAGC GCTTTACCCG AAGCGACCAC CTGAGCAAAC ACCAGCGCAC CCATGGAGAA 
CCAGGCCCGG GTCCCCCTCC CAGTGGCCCC AAGGAGCTGG GGGAGGGCCG CAGCACGGGG 
GAAGAGGAGG CCAGTCAGAC GCCCCGACCT TCTGCCTCGC CAGCAACCCC AGAGAAAGCC 
CCTGGAGGCA GCCCTGAGCA GAGCAACTTG CTGGAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MiR-96 regulates bone metabolism by targeting osterix.
Clinical and experimental pharmacology & physiology(2017 Dec)
Liu H,Liu Q,Wu XP,He HB,Fu L

Osterix Decreases the Chemosensitivity of Breast Cancer Cells by Upregulating GALNT14.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology44(3)998-1010(2017)
Wu J,Chen X,Bao Q,Duan R,Jin Y,Shui Y,Yao B,Lu X,Wang Y,Cui H,Li L,Yuan H,Ma C

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SP7 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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