CHP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CHP1
Entrez Gene ID	11261
Full Name	calcineurin like EF-hand protein 1
Synonyms	CHP,SLC9A1BP,Sid470p,p22,p24
General protein information	Preferred Names calcineurin like EF-hand protein 1 Names calcineurin B homologous protein 1 EF-hand calcium-binding domain-containing protein p22 SLC9A1 binding protein calcineurin B homolog calcineurin B-like protein calcineurin homologous protein calcium binding protein P22 calcium-binding protein CHP calcium-binding protein p22
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q15.1
Summary	This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity. [provided by RefSeq, Jul 2008].
Disorder MIM:	606988

mRNA and Protein(s)

mRNA	Protein	Name
NM_007236.5	NP_009167.1	calcineurin B homologous protein 1
XM_017021879.2	XP_016877368.1	calcineurin B homologous protein 1 isoform X1
XM_017021879.1	XP_016877368.1	calcineurin B homologous protein 1 isoform X1
NM_007236.4	NP_009167.1	calcineurin B homologous protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CHP1	NP_009167.1
	CHP1	XP_001099956.1
Rattus norvegicus (Norway rat)	Chp1	NP_077053.1
Gallus gallus (chicken)	CHP1	NP_001007931.1
Canis lupus familiaris (dog)	CHP1	XP_535438.1
Pan troglodytes (chimpanzee)	CHP1	XP_523056.2
Bos taurus (cattle)	CHP1	NP_001069044.1
Danio rerio (zebrafish)	chp1	NP_956009.1
Drosophila melanogaster (fruit fly)	elm	NP_001262295.1
Caenorhabditis elegans (roundworm)	F59D6.7	NP_503830.2
Xenopus tropicalis (tropical clawed frog)	chp1	NP_001004859.1
Mus musculus (house mouse)	Chp1	NP_062743.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001760	XP_321323.3
Caenorhabditis elegans (roundworm)	ZK856.8	NP_505623.1

Gene Ontology
Bibliography

Related articles in PubMed

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, B?ning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, , Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH
Nature491(7422)119-24(2012 Nov)

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)

SNPs in axon guidance pathway genes and susceptibility for Parkinson's disease in the Korean population.
Kim JM, Park SK, Yang JJ, Shin ES, Lee JY, Yun JY, Kim JS, Park SS, Jeon BS
Journal of human genetics56(2)125-9(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: SNPs in axon guidance pathway genes and susceptibility for Parkinson's disease in the Korean population.

Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
Title: Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.

CHP2 has a role in tumorigenesis and as an activator of the calcineurin/NFAT signaling pathway
Title: CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.

helix formation of the cytoplasmic region of NHE1 by calcineurin B homologous protein 1 is a prerequisite for generating the active form of NHE1
Title: Solution structure of the cytoplasmic region of Na+/H+ exchanger 1 complexed with essential cofactor calcineurin B homologous protein 1.

The following CHP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CHP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12532	NM_007236.5 Latest version!	Homo sapiens calcineurin like EF-hand protein 1 (CHP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu48088	XM_017021879.2 Latest version!	Homo sapiens calcineurin like EF-hand protein 1 (CHP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu48088	XM_017021879.1	Homo sapiens calcineurin like EF-hand protein 1 (CHP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu12532	NM_007236.4	Homo sapiens calcineurin like EF-hand protein 1 (CHP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CHP1 ( NM_007236.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_009167.1 Homo sapiens calcineurin like EF-hand protein 1 (CHP1), mRNA.

Price & Availability↑

CloneID	OHu12532
Clone ID Related Accession (Same CDS sequence)	NM_007236.5 , NM_007236.4
Accession Version	NM_007236.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-22
Organism	Homo sapiens(human)
Product	calcineurin B homologous protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC012652.7. On Nov 22, 2018 this sequence version replaced NM_007236.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.250687.1, SRR1803615.154487.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000334660.10/ ENSP00000335632.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGTTCTC GGGCCTCCAC GTTACTGCGG GACGAAGAGC TCGAGGAGAT CAAGAAGGAG 
ACCGGCTTTT CCCACAGTCA AATCACTCGC CTCTACAGCC GGTTCACCAG CCTGGACAAA 
GGAGAGAATG GGACTCTCAG CCGGGAAGAT TTCCAGAGGA TTCCAGAACT TGCCATCAAC 
CCACTGGGGG ACCGGATCAT CAATGCCTTC TTTCCAGAGG GAGAGGACCA GGTAAACTTC 
CGTGGATTCA TGCGAACTTT GGCTCATTTC CGCCCCATTG AGGATAATGA AAAGAGCAAA 
GATGTGAATG GACCCGAACC ACTCAACAGC CGAAGCAACA AACTGCACTT TGCTTTTCGA 
CTATATGATT TGGATAAAGA TGAAAAGATC TCCCGTGATG AGCTGTTACA GGTGCTACGC 
ATGATGGTCG GAGTAAATAT CTCAGATGAG CAGCTGGGCA GCATCGCAGA CAGGACCATT 
CAGGAGGCTG ATCAGGATGG GGACAGTGCC ATATCTTTCA CAGAATTTGT TAAGGTTTTG 
GAGAAGGTGG ATGTAGAACA GAAAATGAGC ATCCGATTTC TTCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009167.1
CDS	116..703
Translation	MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH

Target ORF information:

RefSeq Version	NM_007236.5
Organism	Homo sapiens(human)
Definition	Homo sapiens calcineurin like EF-hand protein 1 (CHP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007236.5

ORF Insert Sequence:

ATGGGTTCTC GGGCCTCCAC GTTACTGCGG GACGAAGAGC TCGAGGAGAT CAAGAAGGAG 
ACCGGCTTTT CCCACAGTCA AATCACTCGC CTCTACAGCC GGTTCACCAG CCTGGACAAA 
GGAGAGAATG GGACTCTCAG CCGGGAAGAT TTCCAGAGGA TTCCAGAACT TGCCATCAAC 
CCACTGGGGG ACCGGATCAT CAATGCCTTC TTTCCAGAGG GAGAGGACCA GGTAAACTTC 
CGTGGATTCA TGCGAACTTT GGCTCATTTC CGCCCCATTG AGGATAATGA AAAGAGCAAA 
GATGTGAATG GACCCGAACC ACTCAACAGC CGAAGCAACA AACTGCACTT TGCTTTTCGA 
CTATATGATT TGGATAAAGA TGAAAAGATC TCCCGTGATG AGCTGTTACA GGTGCTACGC 
ATGATGGTCG GAGTAAATAT CTCAGATGAG CAGCTGGGCA GCATCGCAGA CAGGACCATT 
CAGGAGGCTG ATCAGGATGG GGACAGTGCC ATATCTTTCA CAGAATTTGT TAAGGTTTTG 
GAGAAGGTGG ATGTAGAACA GAAAATGAGC ATCCGATTTC TTCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHP1 ( NM_007236.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_009167.1 Homo sapiens calcineurin like EF-hand protein 1 (CHP1), mRNA.

Price & Availability↑

CloneID	OHu12532
Clone ID Related Accession (Same CDS sequence)	NM_007236.5 , NM_007236.4
Accession Version	NM_007236.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	calcineurin B homologous protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC012652.7. On Aug 16, 2007 this sequence version replaced NM_007236.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.154487.1, SRR1803616.189895.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTTCTC GGGCCTCCAC GTTACTGCGG GACGAAGAGC TCGAGGAGAT CAAGAAGGAG 
ACCGGCTTTT CCCACAGTCA AATCACTCGC CTCTACAGCC GGTTCACCAG CCTGGACAAA 
GGAGAGAATG GGACTCTCAG CCGGGAAGAT TTCCAGAGGA TTCCAGAACT TGCCATCAAC 
CCACTGGGGG ACCGGATCAT CAATGCCTTC TTTCCAGAGG GAGAGGACCA GGTAAACTTC 
CGTGGATTCA TGCGAACTTT GGCTCATTTC CGCCCCATTG AGGATAATGA AAAGAGCAAA 
GATGTGAATG GACCCGAACC ACTCAACAGC CGAAGCAACA AACTGCACTT TGCTTTTCGA 
CTATATGATT TGGATAAAGA TGAAAAGATC TCCCGTGATG AGCTGTTACA GGTGCTACGC 
ATGATGGTCG GAGTAAATAT CTCAGATGAG CAGCTGGGCA GCATCGCAGA CAGGACCATT 
CAGGAGGCTG ATCAGGATGG GGACAGTGCC ATATCTTTCA CAGAATTTGT TAAGGTTTTG 
GAGAAGGTGG ATGTAGAACA GAAAATGAGC ATCCGATTTC TTCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009167.1
CDS	145..732
Translation	MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH

Target ORF information:

RefSeq Version	NM_007236.4
Organism	Homo sapiens(human)
Definition	Homo sapiens calcineurin like EF-hand protein 1 (CHP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007236.4

ORF Insert Sequence:

ATGGGTTCTC GGGCCTCCAC GTTACTGCGG GACGAAGAGC TCGAGGAGAT CAAGAAGGAG 
ACCGGCTTTT CCCACAGTCA AATCACTCGC CTCTACAGCC GGTTCACCAG CCTGGACAAA 
GGAGAGAATG GGACTCTCAG CCGGGAAGAT TTCCAGAGGA TTCCAGAACT TGCCATCAAC 
CCACTGGGGG ACCGGATCAT CAATGCCTTC TTTCCAGAGG GAGAGGACCA GGTAAACTTC 
CGTGGATTCA TGCGAACTTT GGCTCATTTC CGCCCCATTG AGGATAATGA AAAGAGCAAA 
GATGTGAATG GACCCGAACC ACTCAACAGC CGAAGCAACA AACTGCACTT TGCTTTTCGA 
CTATATGATT TGGATAAAGA TGAAAAGATC TCCCGTGATG AGCTGTTACA GGTGCTACGC 
ATGATGGTCG GAGTAAATAT CTCAGATGAG CAGCTGGGCA GCATCGCAGA CAGGACCATT 
CAGGAGGCTG ATCAGGATGG GGACAGTGCC ATATCTTTCA CAGAATTTGT TAAGGTTTTG 
GAGAAGGTGG ATGTAGAACA GAAAATGAGC ATCCGATTTC TTCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHP1 ( XM_017021879.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877368.1 Homo sapiens calcineurin like EF-hand protein 1 (CHP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu48088
Clone ID Related Accession (Same CDS sequence)	XM_017021879.2 , XM_017021879.1
Accession Version	XM_017021879.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	calcineurin B homologous protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017021879.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTCTC GGGCCTCCAC GTTACTGCGG GACGAAGAGC TCGAGGAGAT CAAGAAGGAG 
ACCGGCTTTT CCCACAGTCA AATCACTCGC CTCTACAGCC GGTTCACCAG CCTGGACAAA 
GGAGAGAATG GGACTCTCAG CCGGGAAGAT TTCCAGAGGA TTCCAGAACT TGCCATCAAC 
CCACTGGGGG ACCGGATCAT CAATGCCTTC TTTCCAGAGG GAGAGGACCA GGTAAACTTC 
CGTGGATTCA TGCGAACTTT GGCTCATTTC CGCCCCATTG AGGATAATGA AAAGAGCAAA 
GATGTGAATG GACCCGAACC ACTCAACAGC CGAAGCAACA AACTGCACTT AGAGGAAGAG 
AGATATATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877368.1
CDS	228..599
Translation	MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHLEEERYI

Target ORF information:

RefSeq Version	XM_017021879.2
Organism	Homo sapiens(human)
Definition	Homo sapiens calcineurin like EF-hand protein 1 (CHP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017021879.2

ORF Insert Sequence:

ATGGGTTCTC GGGCCTCCAC GTTACTGCGG GACGAAGAGC TCGAGGAGAT CAAGAAGGAG 
ACCGGCTTTT CCCACAGTCA AATCACTCGC CTCTACAGCC GGTTCACCAG CCTGGACAAA 
GGAGAGAATG GGACTCTCAG CCGGGAAGAT TTCCAGAGGA TTCCAGAACT TGCCATCAAC 
CCACTGGGGG ACCGGATCAT CAATGCCTTC TTTCCAGAGG GAGAGGACCA GGTAAACTTC 
CGTGGATTCA TGCGAACTTT GGCTCATTTC CGCCCCATTG AGGATAATGA AAAGAGCAAA 
GATGTGAATG GACCCGAACC ACTCAACAGC CGAAGCAACA AACTGCACTT AGAGGAAGAG 
AGATATATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHP1 ( XM_017021879.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877368.1 Homo sapiens calcineurin like EF-hand protein 1 (CHP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu48088
Clone ID Related Accession (Same CDS sequence)	XM_017021879.2 , XM_017021879.1
Accession Version	XM_017021879.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	calcineurin B homologous protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTCTC GGGCCTCCAC GTTACTGCGG GACGAAGAGC TCGAGGAGAT CAAGAAGGAG 
ACCGGCTTTT CCCACAGTCA AATCACTCGC CTCTACAGCC GGTTCACCAG CCTGGACAAA 
GGAGAGAATG GGACTCTCAG CCGGGAAGAT TTCCAGAGGA TTCCAGAACT TGCCATCAAC 
CCACTGGGGG ACCGGATCAT CAATGCCTTC TTTCCAGAGG GAGAGGACCA GGTAAACTTC 
CGTGGATTCA TGCGAACTTT GGCTCATTTC CGCCCCATTG AGGATAATGA AAAGAGCAAA 
GATGTGAATG GACCCGAACC ACTCAACAGC CGAAGCAACA AACTGCACTT AGAGGAAGAG 
AGATATATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877368.1
CDS	235..606
Translation	MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHLEEERYI

Target ORF information:

RefSeq Version	XM_017021879.1
Organism	Homo sapiens(human)
Definition	Homo sapiens calcineurin like EF-hand protein 1 (CHP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017021879.1

ORF Insert Sequence:

ATGGGTTCTC GGGCCTCCAC GTTACTGCGG GACGAAGAGC TCGAGGAGAT CAAGAAGGAG 
ACCGGCTTTT CCCACAGTCA AATCACTCGC CTCTACAGCC GGTTCACCAG CCTGGACAAA 
GGAGAGAATG GGACTCTCAG CCGGGAAGAT TTCCAGAGGA TTCCAGAACT TGCCATCAAC 
CCACTGGGGG ACCGGATCAT CAATGCCTTC TTTCCAGAGG GAGAGGACCA GGTAAACTTC 
CGTGGATTCA TGCGAACTTT GGCTCATTTC CGCCCCATTG AGGATAATGA AAAGAGCAAA 
GATGTGAATG GACCCGAACC ACTCAACAGC CGAAGCAACA AACTGCACTT AGAGGAAGAG 
AGATATATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Nature491(7422)119-24(2012 Nov)
Jostins L,Ripke S,Weersma RK,Duerr RH,McGovern DP,Hui KY,Lee JC,Schumm LP,Sharma Y,Anderson CA,Essers J,Mitrovic M,Ning K,Cleynen I,Theatre E,Spain SL,Raychaudhuri S,Goyette P,Wei Z,Abraham C,Achkar JP,Ahmad T,Amininejad L,Ananthakrishnan AN,Andersen V,Andrews JM,Baidoo L,Balschun T,Bampton PA,Bitton A,Boucher G,Brand S,B?ning C,Cohain A,Cichon S,D'Amato M,De Jong D,Devaney KL,Dubinsky M,Edwards C,Ellinghaus D,Ferguson LR,Franchimont D,Fransen K,Gearry R,Georges M,Gieger C,Glas J,Haritunians T,Hart A,Hawkey C,Hedl M,Hu X,Karlsen TH,Kupcinskas L,Kugathasan S,Latiano A,Laukens D,Lawrance IC,Lees CW,Louis E,Mahy G,Mansfield J,Morgan AR,Mowat C,Newman W,Palmieri O,Ponsioen CY,Potocnik U,Prescott NJ,Regueiro M,Rotter JI,Russell RK,Sanderson JD,Sans M,Satsangi J,Schreiber S,Simms LA,Sventoraityte J,Targan SR,Taylor KD,Tremelling M,Verspaget HW,De Vos M,Wijmenga C,Wilson DC,Winkelmann J,Xavier RJ,Zeissig S,Zhang B,Zhang CK,Zhao H,,Silverberg MS,Annese V,Hakonarson H,Brant SR,Radford-Smith G,Mathew CG,Rioux JD,Schadt EE,Daly MJ,Franke A,Parkes M,Vermeire S,Barrett JC,Cho JH

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Nature cell biology13(4)383-93(2011 Apr)
Kuo JC,Han X,Hsiao CT,Yates JR 3rd,Waterman CM

SNPs in axon guidance pathway genes and susceptibility for Parkinson's disease in the Korean population.
Journal of human genetics56(2)125-9(2011 Feb)
Kim JM,Park SK,Yang JJ,Shin ES,Lee JY,Yun JY,Kim JS,Park SS,Jeon BS

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CHP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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